antibiotics

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PREPARED BY:

Dr.MOHAMMAD SALAH QREA‘2008

The use of antibiotics in dentistry

• Antibiotics: a substance produced by microbes, or a semi-synthetic derivative of a natural substance, that inhibits the growth “bacteriostatic”, or lead to death of that microbe “bacteriocidal”.

Classification of ABs

• Cell wall synthesis inhibitors.

• Protein synthesis inhibitors.

• Folic acid synthesis inhibitors.

• Nucleic acid synthesis inhibitors.

DENACINE®• CAPSULES.• DENACINE 150 = clindamycin HCl (150 mg

clindamycin).• DENACINE 300 = clindamycin HCl (300 mg

clindamycin).• Antibacterial agent.• CONTRAINDICATIONS:• Clindamycin \ lincomycin sensitivity.• In the treatment of meningitis.• SIDE EFFECTS:• Abdominal pain, diarrhea, nausea, vomiting,

allergy, jaundice, colitis, and stools with blood.

Use precautions• Consultation needed in:• Pregnant, breast

feeding, severe renal or hepatic disorder, neuromuscular blocking agents, peptic ulcers, and colitis.

casemghour\day

adults150-300

61x4

More Severe

300-450

61x4

Max.dose1800 mg

MEGACARE®

• CAPSULES + SUSPENSION.• MEGACARE CAPSULES =250 mg flucloxacillin Na(

250 mg ampicillin base).

• MEGACARE CAPSULES forte =250 mg flucloxacillin Na (500 mg ampicillin base).

• MEGACARE suspension = 5 ml -125 mg flucloxacillin Na ( 250 mg ampicillin base).

• Broad-spectrum antibiotic.• CONTRAINDICATIONS:• Sensitivity.• SIDE EFFECTS:• Diarrhea, nausea, vomiting.

Use precautions• Consultation needed in:• Pregnant, breast feeding, severe renal or hepatic

disorder, kidney\UT, blood, peptic ulcers, penicillin sensitivity, and colitis.

• One capsule every 6 hours (1x4x4), before meals or 2 hours after meal.

• Suspension- water and shaking.

CEPROXX®

• CAPLETS + TABLETS .• CEPROXX 250 tab. = ciprofloxacin HCl 250 mg.• CEPROXX 500 capl. = ciprofloxacin HCl 500 mg.• CEPROXX 750 capl. = ciprofloxacin HCl 750 mg.• Broad-spectrum antibiotic.• CONTRAINDICATIONS:• ciprofloxacin sensitivity.• Under 18 years, pregnant and lactating mother.• SIDE EFFECTS:• Abdominal pain, diarrhea, nausea, vomiting,

tremor, blurred vision, and dizziness.

Use precautions• Consultation needed in:• Past epilepsy, liver impairment, kidney\nervous

system, and don’t take the drug with caffeine containing drinks.

• CEPROXX 250 = 20 tablets.• CEPROXX 500 = 10 caplets.• CEPROXX 750 = 10 caplets. "plastic jar”

ERYTHROTAB®

• Each tablet contains erythromycin stearate equivalent to 250 mg erythromycin base.

• Used as alternative to penicillin and in penicillin sensitive patients.

• CONTRAINDICATIONS:

• Sensitivity.

• SIDE EFFECTS:

• Abdominal pain, diarrhea, nausea, vomiting.

Use precautions

• Consultation needed in:

• Pregnant, breast feeding, hepatic disorder.

• 1 hour before, or 2 hours after the meal.• ERYTHROTAB® = box of 24 tablets.

MAGNACILLIN®

• MAGNACILLIN capsules = 250mg ampicillin, and flucloxacillin 250mg.

• MAGNACILLIN forte capsules = 250mg ampicillin, and flucloxacillin 500mg.

• MAGNACILLIN drops= 1ml, 60mg ampicillin, and flucloxacillin 30mg.

• MAGNACILLIN suspension = 5ml, 125mg ampicillin, and flucloxacillin 125mg.

• Broad-spectrum antibiotic.• SIDE EFFECTS:• Epigastric distress and skin rash.

Use precautions• Consultation needed in:• Pregnant and breast feeding.• 1 hour before, or 2 hours after the

meal.• MAGNACILLIN capsules = box of

16 capsules.• MAGNACILLIN forte capsules = jar

of 16 capsules.• MAGNACILLIN drops= glass

bottle of 15 ml.• MAGNACILLIN suspension =

plastic bottle of 60 mg powder or 100 ml.

AMOXITID®

• AMOXITID 250 capsules = amoxycillin 250 mg.• AMOXITID 500 capsules = amoxycillin 500 mg.• AMOXITID 750 capsules = amoxycillin 750 mg.• AMOXITID drops = 1ml, amoxycillin 50 mg.• AMOXITID 125\250\400 suspension = 5ml,

amoxycillin 125\250\400 mg.• Wide spectrum.• Contraindications: sensitivity to ß-lactams such

as cephalosporin.• SIDE EFFECTS:• Diarrhea, nausea, allergy, and change in the

tongue color.

Use precautions• Consultation needed in:• Pregnant and breast feeding.• AMOXITID 250\500 capsules = 16, 200,240 caps.• AMOXITID 750 capsules = 12 caps.• AMOXITID drops = powder\ 15 ml.• AMOXITID 125\250\400 suspension= 60-100 ml.

Ogmin®

• Ogmin 250 tablets = amoxycillin 250 mg, and clavulanic acid 125 mg.

• Ogmin 500 tablets = amoxycillin 500 mg, and clavulanic acid 125 mg.

• Ogmin 875 caplets = amoxycillin 875 mg, and clavulanic acid 125 mg.

• Ogmin 125 suspension = amoxycillin 125 mg, and clavulanic acid 31.25 mg.

• Ogmin 250 suspension = amoxycillin 250 mg, and clavulanic acid 62.5 mg.

• Ogmin 400 suspension = amoxycillin 400 mg, and clavulanic acid 57.1 mg.

• Contraindication as in amoxitid.• SIDE EFFECTS:• Diarrhea, nausea, allergy, and change in the tongue color.

Use precautions• Consultation needed in:• Pregnant and breast

feeding.• Ogmin 250 tablets = plastic

jar of 20 tablets.• Ogmin 500 tablets = plastic

jar of 10-20 tablets.• Ogmin 875 caplets = plastic

jar of 14 caplets.• Ogmin 125 suspension =

powder of 60-100ml.• Ogmin 250 suspension =

powder of 60-100ml.• Ogmin 400 suspension =

powder of 60 ml.

CEFADROX®• CEFADROX 1000 caplets = cefadroxil monohydrate,

1000 mg cefadroxil base.• CEFADROX 500 tablets = cefadroxil monohydrate, 500

mg cefadroxil base.• CEFADROX 125 suspension = 5ml, cefadroxil

monohydrate, 125 mg cefadroxil base.• CEFADROX 250 suspension = 5ml, cefadroxil

monohydrate, 250 mg cefadroxil base.• Used for skin infections, pharyngitis, tonsillitis, & UTI.• SIDE EFFECTS:• Diarrhea, nausea, allergy “urticaria”.

Use precautions• Consultation needed in:• Pregnant and breast feeding.• Dosage:- 25-50 mg\kg\day 1x1 or 1x2.• -1-2 g\kg\day in adults 1x1 or 1x2.• CEFADROX 1000 caplets = 10 caplets.• CEFADROX 500 tablets = 12 tablets.• CEFADROX 125 suspension = powder to 60 ml.• CEFADROX 250 suspension = powder to 60 ml.

BEPEN V.K®

• Each 5ml, contains 250 phenoxymethyl penicillin• Each tablet contains 250-500 mg of phenoxymethyl

penicillin.• Side effects:• Nausea, vomiting, and diarrhea.• Tablets : 20 tablets.• Bottles : powder for 100ml syrup.

ZITROCIN®

• Capsules: 250 mg azithromycin.• Suspension: 200 mg azithromycin.• Macrolide antibiotic.• Consultation needed in:• Pregnant and breast feeding.• Zitrocin 250: 6 capsules.• Zitrocin 200: 15\22.5 ml.

Jeflex®

• Jeflex 250 capsules: 250 mg cephalexin.

• Jeflex 500 capsules: 500 mg cephalexin.

• Jeflex 125 suspension: 5ml,125 mg cephalexin.

• Jeflex 250 suspension: 5ml,250 mg cephalexin.

• Cephalosporin.• Consultation needed in:• Pregnant and breast feeding, allergies.• Jeflex 250 capsules: 16 capsules.

• Jeflex 500 suspension: 60-80 ml.

• Jeflex 250 suspension: 60-80 ml.

CLOXABALPLUS®

• Each capsule contains 500 mg amoxycillic, and 250 mg cloxacillin.

• Boxes of 16 capsules

DOXYPHARM®

• Tablets: 100 mg doxycycline base.• Tetracycline.• Boxes of 10 tablets.

RAFAPEN®

• Rafapen V-K 500 tab.: phenoxymethylpenicillin 500mg.

• RafapenVKforte syrup:5ml, phenoxymethylpenicillin 250 mg.

• Rafapen mega 1000 capl.: phenoxymethylpenicillin 1000mg.

• Penicillin V.

KLACID XL®

• KLACID XL® 500 tab.: clarithromycin 500mg.

• Clarithromycin.

• Adults : 500mg tab. A day. 1x1 with food.

CEFALEX®

• CEFALEX 250 capsules: 250 mg cephalexin.

• CEFALEX 500 capsules: 500 mg cephalexin.

• CEFALEX 125 suspension: 5ml,125 mg cephalexin.

• CEFALEX 250 suspension: 5ml,250 mg cephalexin.

10 kg bw20 kg bw40 kg bw

CEFALEX susp. 125mg\5ml

.5-1 tsp q.i.d.

1-2 tsp b.i.d

1-2 tsp q.i.d

2-4 tsp b.i.d

2-4 tsp q.i.d

4-8 tsp b.i.d

CEFALEX susp. 250 mg\5ml

.25.-5 tsp 1x4

.5 -1 tsp 1x2

.5 -1 tsp 1x4

1-2 tsp 1x2

1-2 tsp 1x4

2-4 tsp 1x2

LARICID®

• LARICID 250 tablets: 250 mg clarithromycin.

• LARICID 500 tablets: 500 mg clarithromycin.

• LARICID 125 suspension: 5ml,125 mg clarithromycin.

• LARICID 250 suspension: 5ml, 250 mg clarithromycin.

• Clarithromycin • Laricid 250: box of 14 tablets.• Laricid 500: box of 14 tablets.• Laricid 250\125 suspension : 60 ml.

KLARIMAX®

• KLARIMAX 500 caplets: 500 mg clarithromycin.• KLARIMAX 250 suspension: 250 mg clarithromycin, in 5ml.• KLARIMAX 125 suspension: 125 mg clarithromycin, in 5ml.• Macrolide antibiotic.• KLARIMAX 500 caplets: 14 caplets.• KLARIMAX 250 suspension: 60 ml.• KLARIMAX 125 suspension: 60 ml.

® ® ® ® ® ® ®Active ing.Dosage Tx. Line ☺☺☺DENACINclindamycin150-300mg\6hr bone infect.\2nd l.t

MEGACAREFlucloxacillin+ampicillin1x4Broad spectrum

CEPROXXciprofloxacin1st line treatment

ERYTHROTABerythromycin500mg (1x1x12)2nd line treatment.

MagnacillinFlucloxacillin+ampicillin1x41st line treatment

Amoxitidamoxycillin500mg (1x3x5)1st line treatment

Ogmin Co-amoxicillin.625mg (1x3x3)2nd line treatment.

CEFADROXCefadroxil 1-2 g\day (1x1\1x2)

1st line treatment.

BEPEN V.Kphenoxymethylpenicillin 500mg (1x4)Narrow spectrum

MOXEPHARMAmoxycillin 500mg (1x3x5)1st line treatment

ZITROCINAzithromycin 500mg (1x1x3)2nd line treatment

Jeflex \KeflexCephalexin 500mg (1x4x4)1st line treatment

CLOXABAL PLUSAmoxycillin+cloxacillin500mg (1x3x5)1st line treatment

DOXYPHARMDoxycyclin 100mg (1x2x5)

Periodontal ds.

RAFAPENPhenoxymethylpenicillin 500mg (1x4)

Narrow spectrum

KLACID XLClarithromycin 500mg (1x2)

2nd line treatment

CEFALEX Cephalexin 500mg (1x4x4)

1st line treatment

ZennatCefurixime 500mg (1x2)

2nd line treatment

☺ red means 1st line treatment

☺ green means 2nd line treatment.

Study hard…before the use of the blade !!!