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MODES OF MECHANICAL VENTILATION

Mazen Kherallah, MD, FCCP

POINTS OF DISCUSSIONS

Advanced Basics:Flow and TimeLimit and cyclingRise TimeVolume vs Pressure Control

Mandatory Modes of VentilationControlled Mandatory Ventilation (CMV or IPPV)

Triggered Modes of VentilationContinuous Positive Airway Pressure (CPAP) Pressure Support Ventilation (PSV)

Hybrid Modes of VentilationAssist Control Mode (A/C)Synchronized Intermittent Mandatory Ventilation (SIMV)

ADVANCED BASICS

RESPIRATORY CYCLE

Inspiration

Expiration

ExpInsp

RELATIONSHIP BETWEEN TIDAL VOLUME, INSPIRATORY TIME AND FLOW

VT 1

Ti a

VT 2

VT 3

Time

Volume

Flow= 30 L/min

Flow= 15 L/min

Flow= 37.5 L/min

ExpExpInspInspInsp

RELATIONSHIP BETWEEN TIDAL VOLUME, INSPIRATORY TIME AND FLOW

VT 1

Ti a

Time

Volume

Ti b Ti c

Flow= 30 L/min

Flow= 20 L/min

Flow= 60 L/min

PRESSURE LIMITED BREATH

Time

Volume

Pressure Limit

EXPIRATORY FLOW CYCLING

Time

Flow

50%

100%

Flow Cycling

RISE TIME

Time

Flow

Pressure

Volume

TI TE

MANDATORY, SPONTANEOUS AND TRIGGEREDINSPIRATORY CYCLING

M

S

Tsynch

M M

M

MM

M

M

S

M

Tsupp Tsupp

Tsupp Tsupp

Tsupp

Tsupp

S

VOLUME CONTROLLED INFLATION

Time

Flow

Pressure

Volume

TI TE

Tidal Volume

If compliance decreases the pressure increases to maintain the same Vt

1 2 3 4 5 6

SEC

1 2 3 4 5 6

PawcmH20

50

-20

120

120

SEC

INSP

EXH

FlowL/min

VOLUME CONTROL BREATHS

Decreased Compliance

VOLUME CONTROL WITH END-INSPIRATORYPAUSE

Time

Flow

Pressure

Volume

TI TE

Tidal Volume

End Inspiratory Pause

PRESSURE CONTROLLED INFLATION

Time

Flow

Pressure

Volume

TI TE

Tidal Volume

Rise Time

Peak Inspiratory Flow

Inspiration Expiration

0 120

00 1 2

3

-3

0

20

0 21

20

00 1 2

3

-3

0

20

0 2

Inspiration Expiration

Volume/Flow Control Pressure Control

Time (s) Time (s)

PawPaw

Pressure

Volume

Flow

TRIGGERED MODES OFVENTILATIONCPAP and PSVV

SPONTANEOUS BREATHING

Time (sec)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

CONTINUOUS POSITIVE AIRWAY PRESSURE(CPAP)

Time (sec)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

CPAP Level

PRESSURE SUPPORT VENTILATION(PSV)

Time (sec)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

Set PS Level

Flow Cycling

Better Efforts

Longer Inspiration

Patient Triggered, Flow Cycled, Pressure limited Mode

CPAP+PSV

Time (sec)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

Set PS Level

Flow Cycling

Patient Triggered, Flow Cycled, Pressure limited Mode

CPAP Level

TRIGGERED MODES OF VENTILATIONPRESSURE SUPPORT VENTILATION

Control Trigger Limit Target Cycle

Pressure Patient Pressure Flow

Patient Triggered Flow Cycled Ventilation

PRESSURE OR VOLUME-TARGETEDVENTILATION

Full to partial ventilatory supportAugments the patients spontaneous VTDecreases the patient’s spontaneous respiratory rateDecreases patient WOB by overcoming the resistance of the artificial airway, vent circuit and demand valvesAllows patient control of TI, Vm I, f and VTSet peak pressurePrevents respiratory muscle atrophyFacilitates weaningImproves patient comfort and reduces need for sedationMay be applied in any mode that allows spontaneous breathing, e.g., VC-SIMV, PC-SIMV

Requires consistent spontaneous ventilationPatients in stand-alone mode should have back-up ventilationVT variable and dependant on lung characteristics and synchronyLow exhaled VE

Fatigue and tachypnea if PS level is set too low

Advantages Disadvantages

MANDATORY MODES OFVENTILATIONCMV or IPPV

MANDATORY MODES OF VENTILATIONCMV

Control Trigger Limit Target Cycle

PressureOr

Volume

Time Time

Time Triggered Time Cycled Ventilation

CONTROL MODE(PRESSURE-TARGETED VENTILATION)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

Time Triggered, Pressure Limited, Time Cycled Ventilation Time (sec)

Time CyclingSet PC Level

CONTROL MODE(VOLUME-TARGETED VENTILATION)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

Time Triggered, Flow Limited, Volume Cycled Ventilation Time (sec)

Preset VTVolume Cycling

Time Cycling

Dependent onCL & Raw

PRESSURE OR VOLUME-TARGETEDVENTILATION

Decreases the work of breathing (WOB)Helps maintain a normal PaCO2

Not able to assist the ventilator

Advantages Disadvantages

HYBRID MODES OFVENTILATIONSIMV and A/C

HYBRID MODES OF VENTILATIONA/C

Control Trigger Limit Target Cycle

PressureOr

Volume

Time Or

Patient

Time

Time or PatientTriggered Time Cycled Ventilation

ASSISTED MODE(VOLUME-TARGETED VENTILATION)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

Patient Triggered, Flow limited, Volume Cycled Ventilation Time (sec)

Preset peak Flow

Time Cycling

ASSISTED MODE(PRESSURE-TARGETED VENTILATION)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

Patient Triggered, Pressure Limited, Time Cycled Ventilation Time (sec)

Time CyclingSet PC Level

PRESSURE OR VOLUME-TARGETEDVENTILATION

Decreases the work of breathing (WOB)Allows patients to regulate respiratory rateHelps maintain a normal PaCO2

Alveolar hyperventilation

Advantages Disadvantages

HYBRID MODES OF VENTILATIONSIMV/PS

Breath Type

Control Trigger Limit Cycle

Mandatory PressureOr

Volume

Time Or

Patient

Time

Spontaneous Pressure Patient Pressure Flow

SIMV(VOLUME TARGETED VENTILATION)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

Spontaneous Breaths

M M M

Time (sec)

SIMV+PS(VOLUME TARGETED VENTILATION)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

MTsuppTsynch

Set PS Level

Flow-cycled

Time (sec)

SIMV + PS (PRESSURE-TARGETED VENTILATION)

Flow(L/m)

Pressure(cm H2O)

Volume(mL)

Tsupp

Tsynch

Time CycledFlow-cycled

Tsynch

Set PC Level Set PS Level

Time (sec)

HYBRID MODE VENTILATION: SUPPRESSION

Time (sec)

Flow

(L/m

)Pr

essu

re(c

m H

2O)

Cyc

les

M Tsupp MM Tsupp

M M

Tsupp Tsupp

HYBRID MODE VENTILATION: SYNCHRONIZATION(SIMV+PSV)

Time (sec)

Flow(L/m)

Pressure(cm H2O)

Cycles

Triggered window for supported breaths

Triggered window for synchronized breaths

Mandatory Cycle Time

M Tsupp Tsynch M Tsynch Tsupp

SIMV

Maintains respiratory muscle strength by avoiding muscle atrophyDecreases mean airway pressureFacilitates ventilator discontinuation –“weaning”!

When used for weaning, may be done too quickly and cause muscle fatigueMechanical rate and spontaneous rate may asynchronous causing “stacking”

May cause barotrauma or volutrauma

Advantages Disadvantages

ALL MODES TABLES

Mandatory Modes of VentilationsMandatory breaths

Inspiratory cycling Time Time Time Time

Control Volume Volume Volume (Pressure)

Target/Limit - Pressure-limited Volume-targeted

Feeadback - - Intra-breath Inter-breathExpiratory cycling Time Time Time TimeTriggered BreathsTypes None None None None

Supported Breaths

Control - - - -Target - - - -Feedback - - - -Expiratory Cycling - - - -Spontaneous Breaths

During mandatory inspiration Not accommodated

Not accommodated

Not accommodated Accommodated

Otherwise Not accommodated Accommodated Not

accommodated Accommodated

Synonyms

IPPV (Draeger)Controlled Mandatory Ventilation

Intermittent Mandatory Ventilation

IPPV (Draeger): trigger off, autoflow off

IPPV (Draeger): trigger off,autoflow on

Triggered Modes of Ventilations

Mandatory breaths

Inspiratory cycling - - -

Control - - -

Target/Limit - - -

Feeadback - - -

Expiratory cycling - - -

Triggered Breaths

Types Supported breaths Supported breaths Supported breaths

Supported Breaths

Control Pressure (Pressure) (Pressure)

Target -- Volume-targeted Flow and Volume

Feedback -- Inter-breath Intra-breath

Expiratory Cycling Flow Flow Flow

Spontaneous Breaths

During mandatory inspiration - - -

Otherwise - - -

Synonyms

Assisted Spontaneus Breathing (Draeger)Spontaneous Mode (Hamilton, Puritan Bennet)Pressure Support (MaquetPressure Support Ventilation (Viasys)CPAP (Respironics)

Volume Support (Maquet, Puritan-Bennett)

Propotional Assist Ventilation, Proportional Pressure Suport (Draeger)Propotional Assist Ventilation Plus (Puritan-Bennet)

Hybrid Mode: Assist Control

Mandatory breaths

Inspiratory cycling Time or trigger Time or trigger Time or trigger

Control Volume Pressure (Pressure)

Target/Limit - - Volume-targeted

Feeadback - - Inter-breath

Expiratory cycling Time Time Time

Triggered Breaths

Types Mandatory pattern Mandatory pattern Mandatory pattern

Supported Breaths

Control - - -

Target - - -

Feedback - - -

Expiratory Cycling - - -

Spontaneous Breaths

During mandatory inspiration Not accommodated Accommodated Accommodated

Otherwise - - -

Synonyms

IPPVASSIST (Draeger)Synchronized cCntrolledMandatory Ventilation (Hamilton)Volume Control (Maquet)VCV-A/C (Puritan-Bennett, Respironics)Volume A/C (Viasys)

BIPAPASSIST (Draeger)P-CMV (Hamilton)Pressure Control (Maquet)PCV-A/C (Puritan-Bennett, Respironics)Pressure A/C (Viasys)

Adaptive Pressure Ventilation CMVPRVC (Maquet)VC+A/C (Puritan-Bennet)PRVC A/C (Viasys)IPPV Assist Autoflow(Draeger)

Hybrid Mode: Synchronized Intermittent Mandatory Ventilation

Mandatory breaths

Inspiratory cycling Time or trigger Time or trigger Time or trigger

Control Volume Pressure (Pressure)

Target/Limit - - Volume-targeted

Feeadback - - Inter-breath

Expiratory cycling Time Time Time

Triggered Breaths

Types Mandatory and supported pattern

Mandatory and supported pattern

Mandatory and supported pattern

Supported Breaths

Control Pressure Pressure Pressure

Target - - -

Feedback - - -

Expiratory Cycling Flow Flow Flow

Spontaneous Breaths

During mandatory inspiration Not accommodated Accommodated Accommodated

Otherwise Only if support is off Only if support is off Only if support is off

Synonyms

SIMV (Draeger, Hamilton)SIMV (VC)+PS (Maquet)VCV-SIMV (Puritan-Bennett, Respironics)Volume SIMV (Viasys)

P-SIMV (Hamilton)SIMV(PC)+PS (Maquet)PCV-SIMV (Puritan-Bennett, Respironics)Pressure SIMV (Viasys)

SIMV+AutoflowAdaptive Pressure Ventilation SIMV (Hamilton)SIMV (PRVC)+PS (Puritan-Bennett)PRVC SIMV (Viasys)

Hybrid Mode: Bi-Level Ventilatio

Mandatory breaths

Inspiratory cycling Time or trigger Time or trigger Time or trigger Time or trigger

Control Pressure Pressure Pressure Pressure

Target/Limit - - - -

Feeadback - - - -

Expiratory cycling Time or trigger Time or trigger Time or trigger Time or trigger

Triggered Breaths

Interaction Mandatory and supported

Mandatory pattern and supported

Mandatory and supported

Mandatory and supported

Supported Breaths

Control Pressure Pressure Pressure Pressure

Target - - - -

Feedback - - - -

Expiratory Cycling Flow Flow Flow Flow

Spontaneous Breaths

During mandatory inspiration Accommodated

Trigers suuport to PEEP+Psupport If this>Phigh (Hamilton DuoPAP)Plow+Psupport If this>Phigh (Hamilton APRV)PEEPL+PsuppIf this>PEEPH (Puritan-Bennett)

Triggers support to PRES HIGH + PSV if Thigh PSV is activated

Tigger support to PSV above PHigh

Otherwise Triggers support

Triggers support to PEEP+Psupport(Hamilton) DuoPAP)Plow+Psupport (Hamilton APRV)PEEPL+Psupp (Puritan-Bennett)

Triggers support to PREDSLOW=PSV

Triggers support to PSV above PEEP

Synonyms BIPAP (Draeger)

DuoPAP/APRV (Hamilton)BiLevel (Puritan-Bennet)

APRV/Bi-phasic(Viasys) Bi-vent (Maquet)

THANK YOU

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