breast cancer overview polly stephens, m.d.. breast anatomy

BREAST CANCER OVERVIEW Polly Stephens, M.D.

BREAST ANATOMY

breastcancer.org

Ductal Carcinoma In Situ

Calcifications

CALCIFICATIONS

                                                                                                                   The 

Invasive Ductal Carcinoma

Breast cancer

Breast cancer

Vascular/Lymphatic Invasion

Bone scan

Liver metastases

MAMMOGRAPHY

In America, most breast cancers are diagnosed on mammogram

• 1st mammogram age 35 – Or 10 years before your mother was

diagnosed with breast cancer• Yearly starting age 40• About 10% of cancers are not seen on

mammogram. DO YOUR OWN EXAM

St Francis Cancer Institute

BIOPSY

• Ultrasound-guided• Stereotactic• MRI guided biopsy

STEREOTACTIC BIOPSY

ULTRASOUND BIOPSY

INVASIVE DUCTAL CARCINOMA

• Overall survival 75%• Stage

– 0 Ductal carcinoma in situ– I tumor <2cm, no lymph nodes– II tumor 2-5cm, <4 lymph nodes– III tumor >5cm, >4 lymph nodes– IV distant metastases

INFLAMMATORY BREAST CANCER

• P’eau d’orange

Treatment

• Local control– Lumpectomy/mastectomy– Radiation

• Distal control– Chemotherapy

Sentinel node biopsy

Mammosite

External Beam Radiation

Who needs chemotherapy?

• If there is a risk of cells in the blood stream looking for a place to settle– Bone, Liver, Lung, Brain

• There is no blood test for breast cancer cells in the blood stream

Genetics

• BRCA 1 and 2– Alterations or mutations in these genes

increase ones risk for breast and ovarian cancer

– Only about 5% of breast cancer patients are BRCA +