cell division mitosis cell cycle resource booklet
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Cell Division
Mitosis
Cell Cycle Resource Booklet
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InterphaseDescription : A period
of growth in which a cell can spend 90% of its time. This part of the cycle is divided into three phases: G1, S, and G2.
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InterphasePlant cell
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InterphaseAnimal cell
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Interphase
Chromatin is a mass of genetic material composed of DNA and proteins that eventually condenses to form chromosomes
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G1 (Gap 1)
Description : A period of activity in which cells do most of their growing. Cells increase in size and synthesize new proteins and organelles.
The G1 checkpoint ensures that the cell is large enough to divide, and that enough nutrients are available to support the resulting daughter cells.
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S (Synthesis)
Description : Synthesis of DNA molecules takes place as chromosomes are replicated. Key proteins are also synthesized.
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S (Synthesis)DNA replication: Use the color code key to color the replicating DNA strand in your resource book.
Nitrogenous Bases Color Key Adenine Thymine Guanine Cytosine
Nitrogenous Bases Color Key Adenine Thymine Guanine Cytosine
Nitrogenous Bases Color Key Adenine Thymine Guanine Cytosine
Nitrogenous Bases Color Key Adenine Thymine Guanine Cytosine
Nitrogenous Bases Color Key Adenine Thymine Guanine Cytosine
Nitrogenous Bases Color Key Adenine Thymine Guanine Cytosine
Nitrogenous Bases Color Key Adenine Thymine Guanine Cytosine
Nitrogenous Bases Color Key Adenine Thymine Guanine Cytosine
Nitrogenous Bases Color Key Adenine Thymine Guanine Cytosine
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G2 (Gap 2)
Description: Many organelles and molecules required for cell division are produced here. Once this phase is complete, the cell is ready for mitosis.
The G2 checkpoint ensures that DNA replication in S phase has been completed successfully.
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ProphaseDescription: The chromatin condenses into
chromosomes. The centrioles (in animals) separate, and a
spindle begins to form.
The nuclear envelope breaks down. Longest phase of mitosis.
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ProphasePlant cell
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ProphaseAnimal cell
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MetaphaseDescription:
The chromosomes line up across the center of the cell.
Each chromosome is connected to a spindle fiber at its centromere.
Metaphase checkpoint ensures that all of the chromosomes are attached to the mitotic spindle by a kinetochore .
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MetaphasePlant cell
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Metaphase
Animal cell
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Anaphase
Description: The sister chromatids separate into
individual chromosomes and are moved apart.
A cell plate forms in plant cells.
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AnaphasePlant cell
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AnaphaseAnimal cell
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TelophaseDescription: Nuclear envelope forms around each
new set of chromosomes
Spindle breaks down
Chromosomes uncoil
A cell wall begins to form in plant cells.
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TelophasePlant cell
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TelophaseAnimal cell
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CytokinesisDescription:Cytoplasm pinches in
half.Daughter cells have
an identical set of duplicate chromosomes.
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CytokinesisPlant cell
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CytokinesisAnimal cell
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Phase IdentificationLook at the onion root tip cells in your booklet and seehow many cells you can find in each stage.
Chose a color for each stage and outline the cell in thatcolor.
Cell Division Color Key
Interphase
Prophase
Metaphase
Anaphase
TelophaseCytokinesis
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G0 (G zero) If the cell does not receive a signal to
“go ahead” at the G1 checkpoint it will not go into the dividing phases (Mitosis)
The cell is now said to be in G0
Most cells in your body are in this stage.
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G0 (G zero) Examples of cells in G0
– Nerve cells– muscle cells– Liver cells (although these cells can be
“called back” into the dividing phases of mitosis based on external cues such as growth factors)
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Cancer Cancer is a disorder in which some of the
body’s own cells lose the ability to control growth.
Cancer cells do not respond to the signals that regulate the growth of most cells (G1 checkpoint is bypassed).
As a result, they divide uncontrollably and form masses of cells called tumors that can damage the surrounding tissues.
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Cancer Cause/EffectWhat causes the loss of growth control that causes cancer??
Use the Cancer Cause/Effect powerpoint to fill in this map.Fill in the various causes of cancer.Fill in the effects for each cause.
CANCER
Videos
Cell Cycle http://www.youtube.com/watch?v=NR0mdDJMHIQ
Cancer http://www.youtube.com/watch?v=acUl9JC70e8 http://www.youtube.com/watch?v=IeUANxFVXKc
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