cheminform abstract: formal synthesis of roseophilin
Post on 06-Jun-2016
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1999 antibiotics
antibioticsU 1200
47 - 244Formal Synthesis of Roseophilin. — A thirteen step route to thetricyclic ketopyrrole core of roseophilin is presented in which the key steps arethe radical macrocyclization under high dilution conditions and the Paal-Knorrpyrrole synthesis that proceeds with in situ oxidation. — (ROBERTSON,JEREMY; HATLEY, RICHARD J. D.; Chem. Commun. (Cambridge) (1999)16, 1455-1456; Dyson Perrins Lab., Dep. Chem., Univ. Oxford, Oxford OX13QY, UK; EN)
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