church apr2013

Human Genomes

The Human Genome Project

Figure 1. Identification of recombination events.

Chowdhury R, Bois PRJ, Feingold E, Sherman SL, et al. (2009) Genetic Analysis of Variation in Human Meiotic Recombination. PLoS Genet 5(9): e1000648. doi:10.1371/journal.pgen.1000648http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000648

color colour

week weak

week wlek

Figure 1. Sequence Structure of Structural Variant and Genotyping Assay Design

Kidd JM, Newman TL, Tuzun E, Kaul R, et al. (2007) Population Stratification of a Common APOBEC Gene Deletion Polymorphism. PLoS Genet 3(4): e63. doi:10.1371/journal.pgen.0030063http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030063

Clones

Clones

IHGSC, Nature 2004

RP11-34P13 64E8 RP4-669L17 RP5-857K21 RP11-206L10 RP11-54O7

Gaps

http://theamazingios6maps.tumblr.com/

Preview of GRCh38 (scheduled Fall 2013)

TEX28 TKTL1

LOC101060233(opsin related)

LOC101060234(TEX28 related)

GRCh37 (current reference assembly)chrX

23andMe

NOT

Matsunaga (1962)