formal empirical applied mathematical and technical methods and theories cognitive, behavioral, and...

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

Informatics Informatics Methods in Methods in

Biomedicine: Biomedicine:

Foundations of a Foundations of a ProfessionProfession

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

Molecul

es Cells Tissues

Organs Patient Populatio

n

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

ClinicalClinical

Basic SciencesBasic SciencesPreclinicalPreclinical

Post-docPost-doc

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Mathematical and technicalMathematical and technicalmethods and theories methods and theories

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

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Cognitive, behavioral, and organizational Cognitive, behavioral, and organizational techniques and theories techniques and theories

ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

Prerequisites Prerequisites

Introductory computer science Introductory computer science

• Programming language Programming language

• Data structures Data structures

• AlgorithmsAlgorithms

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic HealthFormal Competencies Formal Competencies

• Systems -Systems - Systems architecture, system Systems architecture, system integration, software engineeringintegration, software engineering

• Knowledge -Knowledge - Data mining, knowledge Data mining, knowledge bases, rule bases, information retrieval bases, rule bases, information retrieval

• Data -Data - Ontology, databases, signal Ontology, databases, signal processing, image processing, sequence processing, image processing, sequence analysisanalysis

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

Prerequisites Prerequisites

• Statistics Statistics • Elementary experimental methods Elementary experimental methods

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic HealthEmpirical Competencies Empirical Competencies

• Systems –Systems – User interfaces, project User interfaces, project management, needs assessment, impact management, needs assessment, impact assessment assessment

• Knowledge –Knowledge – Knowledge acquisition, Knowledge acquisition, decision analysis, computer-aided decision analysis, computer-aided instruction instruction

• Data –Data – Data modeling, visualization, data Data modeling, visualization, data standards, utilization modeling, security, standards, utilization modeling, security, confidentiality confidentiality

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

PrerequisitesPrerequisites

Biomedical sciences Biomedical sciences

• Molecular biologyMolecular biology

• Anatomy Anatomy

• Physiology Physiology

• Public health Public health

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic HealthBioinformatics Bioinformatics Application DomainApplication Domain

• Intro to GenomicsIntro to Genomics

• Computation GenomicsComputation Genomics

• Sequence AnalysisSequence Analysis

• Microarrays and Regulatory NetworksMicroarrays and Regulatory Networks

• Biological DatabaseBiological Database

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic HealthImaging Application Imaging Application DomainDomain

• Biomedical ImagingBiomedical Imaging

• Analysis and Quantification of Medical Analysis and Quantification of Medical ImagesImages

• Wavelet ApplicationsWavelet Applications

• Computation Neural Modeling and Computation Neural Modeling and NeuroengineeringNeuroengineering

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic HealthClinical Application Clinical Application DomainDomain

• Economics of InformaticsEconomics of Informatics

• Project ManagementProject Management

• Interactive Health CommunicationsInteractive Health Communications

• Introduction to Databases and Data MiningIntroduction to Databases and Data Mining

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

Public Health Public Health Application DomainApplication Domain

• Use of Large Scale national health care data Use of Large Scale national health care data setssets

• Hospital Organization and ManagementHospital Organization and Management

• Health CommunicationsHealth Communications

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

Basic ResearchBasic ResearchInformatics Informatics ChallengesChallenges ApplicationsApplications

BioinformatiBioinformaticscs

Biochips, algorithms for DNA sequencing, patient specific drugs

Linking genomic and patient data, security, ethics

Genetic-based patient records and protocols

ImagingImaging

3-D modeling, visualization, data representation

Ontology-based ref models of classification of concepts and visual info

3-D anatomy atlases, radiological diagnosis

ClinicalClinical Coding, data structures, high performance computing

Vocabularies, automated retrieval from repositories

Distributed medical records, clinical trials, teledentistry

Public Public HealthHealth

Databases, searching, data analysis theories and algorithms

Integration and validation of info, knowledge discovery

Data mining, citizen-based services

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

Lessons Learned in Lessons Learned in Training Training

• Acculturation Acculturation

• Depth or Breadth Depth or Breadth

• DDS/PhD DDS/PhD

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ImagingImagingBioInformaticsBioInformatics ClinicalClinical Public HealthPublic Health

Thanks to Thanks to

Dr. Stephen B. JohnsonDr. Stephen B. Johnson

Dr. Ted ShortliffeDr. Ted Shortliffe