golgi apparatus (cell organelle) in eukaryotes

“Cell and Molecular Biology”Rida Shahzad13091514-079

Golgi apparatus discovery, subcellular localization, structure, function and vesicular

transport Presentation Topic:

Golgi Discovery: also known as Golgi complex, Golgi body, or simply the Golgi.

an organelle found in most eukaryotic cells.was identified in 1897 by the Italian physician.“Camillo Golgi”named after him in 1898

Golgi Discovery Owing to it’s larger size, it was one of the first organelles to be discovered and observed.

Camillo discovered it,during an investigation of nervous system.

Subcellular localizationIn mammalsSingle Golgi body is near the cell nucleus, close to centrosome.

Tubular connections responsible for linking stacks together.

Are dependent on microtubules.If microtubules are depolymerized: Then Golgi apparatus loses connection.And becomes individual stacks throughout the cytoplasm.

StructureIn most eukaryotes, Golgi apparatus is made up of a series of compartments consisting of two main networks: cis Golgi network (CGN)

trans Golgi network (TGN).

StructureCGN is a collection of Fused. flattened membrane-enclosed disks. known as cisternae. originating from vesicular clusters. that bud off the endoplasmic reticulum. A mammalian cell typically contains 40 to 100 stacks.Golgi body is absent in few cell types, such as mammalian RBC’s. Sperm cells of bryophytes.

How stacks are formed?

Functions: The cell synthesize a huge

amount of variety of macromolecules.

main function is to modify, sort and package the macromolecules

that are synthesized by the cells. for secretion purposes or for use

within the cell. mainly modifies the proteins that

are prepared by the RER. Create lysosomes.

Vesicular transport Is the active movement of substances across the cell membrane through vesicles.Vesicles form from the Endoplasmic reticulum.

Golgi apparatus.plasma membrane.

Vesicular transport Transport between compartments takes place via

vesicles.Membranes, with both proteins and lipids, and the soluble proteins contained within the vesicles

are transported.For example, once the proteins are in the ER, they are transported by vesicles that bud off of

the ER and fuse with the membrane of the target compartment.

Vesicular transport 1-Exocytosis 2-Endocytosis Phagocytosis.Pinocytosis.Receptor mediated.

Exocytosis and Exocytosis

Pinocytosis, Phagocytosis, Receptor Mediated Endocytosis…

Thank you!