happy holidaze: dr. dave's cure for the holidaze hangover

All photos take by Dr. Dave in Times Square

Sugar iS Sugar iS Sugar.

Your bodY & brain don’t care whether that Sugar comeS from whole wheat paSta and bread,

or…

from m&m’S waShed down with coca-cola (or rum/eggnog & coke).

either waY, theSe Simple carbS can launch a caScade

of eventS that will likelY leave

You in a poSt-holidaY Sugar daze: i.e. the holidaze are

coming

A Few Hangover Points:• Alcohol is neither the only, nor even the most

common, cause of hangovers;• A hangover is actually the one-two punch of acute

intoxication (in-toxic-ation) followed by withdrawal from the toxic agent;

• Recent scientific research has demonstrated that “intense sweetness” is as addicting as cocaine;

• The roller coaster ride of carbohydrate intoxication-withdrawal can cause headache, GI distress, brain fog, irritability, and generalized malaise.

the not So happY

holidazehangover

recipe:• pace• people• preSSure• poor Sleep• poorer diet

holidaze hangover mechaniSm: well, it’S complicated

9Someone you met

Immuno-competent Cell (Macrophage)

Something you et

IL-1β, TNF-α, IL-6

IL-1β, TNF-α, IL-6

HPA

AXIS

PNS

SNS

NE

GCs

Ach

Cytokines signal in the brain:- Saturable transporters- BBB leakiness- Localized production- Binding to receptors on

afferent nerve fibers- Recruitment of activated

cells

NF-κB

Raison CL, Lowry CA, Rook GA.. Arch Gen Psychiatry. 2010 Dec;67(12):1211-24.

i told You it waS complicated. more SimplY…

DOCs

“Someone you met or something you et” (or drank)

Blood sugar (and subsequent insulin)

spike

Systemic Inflammation

causes “Leaky Gut”

Toxic Overload, Nutrient Depletion, & your own unique brand of hangover

Pre-Binge (In the days preceding)Leaky Gut Repair on empty stomachProteolytic Enzymes on empty stomachGreen Coffee Bean Extract 20-30 minutes before meal slows down the rate at which your post-meal blood sugar, insulin, and lipids spikeProbiotics with mealDigestive Enzymes (at the beginning of the meal)

The BingeIncorporate as many of these principles in and immediately around the gluttony:• Go for a walk• Adequate sleep (not during the actual meal)• Fiber• Good fat (animal, olive oil, coconut oil)• Healthy protein (vegetable or wild caught fish, anti-

biotic/hormone free pork and fowl, grass-fed beef)• Lemon• Cinnamon• Cayenne pepper• Moderate amount of alcohol• Vinegar• Tea

Post-Binge (For the Next Several Days)• Neuro Immune PRP Spray (possibly my new favorite way

to kill two birds ((anti-biotic and hormone free)) with one stone/spray – seals the gut and right-sizes your immune response to recently ingested toxin foods and beverages)

• Leaky Gut Repair – “Seal and Heal” the gut • Omega 3 fatty acids (helps gut and lowers inflammation)• Dynamic Greens (a green food somewhat flavorful way of

replenishing all but your B vitamins, lots of enzymes and prebiotics ((what your gut bugs like to eat)))

• FolaNAC – your methylated B vitamins plus N-acetylcysteine, one of our most powerful antioxidants and liver detoxifiers

• Livdetox – to help your liver process the acute increase in immune and oxidative stress

• Get back to the other fundamentals of building health

oh, bY the waY, happY holidaze

for more information click, duh, the button below.

1) Visit us online at Integrativepsychiatry.net2) Arrange for an individual consultation:

(800) 385-78633) Email us: info@integrativepsychiatry.net