helen knaggs, phd vice president, global research & development

HELEN KNAGGS, PhDVICE PRESIDENT, GLOBAL RESEARCH & DEVELOPMENT

COMPETITIVE ADVANTAGETARGETING THE SOURCES OF AGING

NU SKIN’S ANTI-AGING APPROACH

Small set of robust biomarkers for rapid screening of nutrients and phytochemicals

DNA Microarray Gene MapOver 20000 Genes

IT’S ALL ABOUT BALANCE

Factors influencing

signs of youth

Factors influencing

signs of aging Anti-aging science

COMPETITIVE ADVANTAGE SCIENCE

• We can identify the sources of aging

• We can target the YGCs

CHARACTERISTIC FEATURES OF SKIN AGING

ELASTIN FIBERS & SKIN ELASTICITY

• Young skin is abundant in elastin fibers• As skin ages, elastin levels decrease• Skin loses contour and firmness, skin sags• Ethocyn® increases important components of skin.

This has been proven (p < 0.001) in controlled, punch biopsy clinical trials at major university medical centers

ETHOCYN® CLINICAL TRIALSPercent Increase In Elastin Content

Percent Increase In Elastin Content

FIRMING FOCUSED YGC*

Skin Structure

FirmingImproves Sagging

Contours

Defines

*A subset of the Skin Structure YGC

ANTI-AGING SCIENCE

AGELOC IS A PROVEN BRANDOVER $1 BILLIONIN AGELOC SALES SINCE Q4 2009

TRU FACE

ESSENCE ULTRA

• All the same benefits plus…

*Based off a commissioned third-party clinical study

• Targets the sources of aging• Contains ageLOC proprietary blend• More firming ingredients• Majority of people saw results in one week*• Continuous improvement in overall skin

firmness• Consumer feedback suggests it feels better on

the skin

Percent Improvement Over Baseline

CLINICAL RESULTS

• 53% overall skin firmness.

• 66% skin firmness around the eyes.

18%21%

30%

44%41%

55%

66%

53%

CLINICAL RESULTS

These results represent the highest response to a Tru Face Essence product that Nu Skin has ever seen in these time frames!

Percent of Subjects

55% 55%

80%80%

AGELOC TRU FACE ESSENCE ULTRA

Leave undefined skin in the past and enjoy firmer, younger looking skin today and in the future with ageLOC Tru Face Essence Ultra