kitten with pruritis
Post on 21-Mar-2016
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Kitten with Pruritis
Dennis B. DeNicola, DVM, PhD, DACVPChief Veterinary Educator
IDEXX Laboratories
“Kitten” – 6 month old DSH6 months oldIntact femaleDomestic Shorthair
Presented with clinical history of pruritis
Cat was depressed upon presentation but became extremely excited during blood collection process
“Kitten” – 6 month old DSHWBC = 17.76 K/L ( 5.50 – 19.50 )LYM = 2.36 K/L ( 0.90 – 7.00 )MONO = 1.78 K/L HIGH ( 0.10 – 0.79 )NEU = 12.29 K/L ( 2.50 – 12.50 )EOS = 1.29 K/L ( 0.10 – 0.79 )BASO = 0.05 K/L ( 0.00 – 0.10 )%LYM = 13.3 %%MONO = 10.0 %%NEU = 69.2 %%EOS = 7.2 %%BASO = 0.3 %HCT = 23.9 % LOW ( 30.0 – 45.0 )RBC = 6.11 M/L ( 5.00 – 10.00 )HGB = 8.5 g/dL ( 8.0 – 15.1 )RETIC = 102.8 K/L%RETIC = 1.7 %MCV = 39.1 fL LOW ( 41.0 – 58.0 )RDW = 22.7 % HIGH ( 17.3 – 22.0 )MCHC = 35.5 g/dL ( 29.0 – 36.0 )MCH = 13.86 pg ( 12.50 – 17.60 )PLT = 905 K/L HIGH ( 175 – 600 )MPV = 16.69 fLPCT = 1.5 %PDW = 17.9 %
“Kitten” – 6 month old DSHErythronHCT = 23.9 % LOW ( 30.0 – 45.0 )RBC = 6.11 M/L ( 5.00 – 10.00 )HGB = 8.5 g/dL ( 8.0 – 15.1 )RETIC = 102.8 K/L%RETIC = 1.7 %MCV = 39.1 fL LOW ( 41.0 – 58.0 )RDW = 22.7 % HIGH ( 17.3 – 22.0 )MCHC = 35.5 g/dL ( 29.0 – 36.0 )MCH = 13.86 pg (12.50 – 17.60)
“Kitten” – 6 month old DSHErythronHCT = 23.9 % LOW ( 30.0 – 45.0 )RBC = 6.11 M/L ( 5.00 – 10.00 )HGB = 8.5 g/dL ( 8.0 – 15.1 )
“Kitten” – 6 month old DSHErythronHCT = 23.9 % LOW ( 30.0 – 45.0 )RBC = 6.11 M/L ( 5.00 – 10.00 )HGB = 8.5 g/dL ( 8.0 – 15.1 )
Anemia Mild
“Kitten” – 6 month old DSHErythronHCT = 23.9 % LOW ( 30.0 – 45.0 )RBC = 6.11 M/L ( 5.00 – 10.00 )HGB = 8.5 g/dL ( 8.0 – 15.1 )RETIC = 102.8 K/L%RETIC = 1.7 %
“Kitten” – 6 month old DSHErythronHCT = 23.9 % LOW ( 30.0 – 45.0 )RBC = 6.11 M/L ( 5.00 – 10.00 )HGB = 8.5 g/dL ( 8.0 – 15.1 )RETIC = 102.8 K/L%RETIC = 1.7 %
Anemia Mild, regenerative
“Kitten” – 6 month old DSHErythronHCT = 23.9 % LOW ( 30.0 – 45.0 )RBC = 6.11 M/L ( 5.00 – 10.00 )HGB = 8.5 g/dL ( 8.0 – 15.1 )RETIC = 102.8 K/L%RETIC = 1.7 %MCV = 39.1 fL LOW ( 41.0 – 58.0 )RDW = 22.7 % HIGH ( 17.3 – 22.0 )MCHC = 35.5 g/dL ( 29.0 – 36.0 )MCH = 13.86 pg (12.50 – 17.60)
“Kitten” – 6 month old DSHErythronHCT = 23.9 % LOW ( 30.0 – 45.0 )RBC = 6.11 M/L ( 5.00 – 10.00 )HGB = 8.5 g/dL ( 8.0 – 15.1 )RETIC = 102.8 K/L%RETIC = 1.7 %MCV = 39.1 fL LOW ( 41.0 – 58.0 )RDW = 22.7 % HIGH ( 17.3 – 22.0 )MCHC = 35.5 g/dL ( 29.0 – 36.0 )MCH = 13.86 pg (12.50 – 17.60)
Anemia Mild, regenerative, microcytic and potential mild
anisocytosis
Erythron – Data InterpretationAnemia
MildMicrocytic (decreased MCV) Regenerative (increased Reticulocyte Count)Potential mild anisocytosis (increased RDW)
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film InterpretationAnemia
MildRegenerative - reticulocytosis
PolychromasiaAnisocytosis
Erythron – Blood Film InterpretationAnemia
MildRegenerative - reticulocytosis
PolychromasiaAnisocytosis
Blood loss anemiaDeveloping Iron deficiency
“Kitten” – 6 month old DSHLeukonWBC = 17.76 K/L ( 5.50 – 19.50 )LYM = 2.36 K/L ( 0.90 – 7.00 )MONO = 1.78 K/L HIGH ( 0.10 – 0.79 )NEU = 12.29 K/L ( 2.50 – 12.50 )EOS = 1.29 K/L ( 0.10 – 0..79 )BASO = 0.05 K/L ( 0.00 – 0.10 )%LYM = 13.3 %%MONO = 10.0 %%NEU = 69.2 %%EOS = 7.2 %%BASO = 0.3 %
“Kitten” – 6 month old DSHLeukonWBC = 17.76 K/L ( 5.50 – 19.50 )
High normal leukocyte count
“Kitten” – 6 month old DSHLeukonWBC = 17.76 K/L ( 5.50 – 19.50 )LYM = 2.36 K/L ( 0.90 – 7.00 )MONO = 1.78 K/L HIGH ( 0.10 – 0.79 )NEU = 12.29 K/L ( 2.50 – 12.50 )EOS = 1.29 K/L ( 0.10 – 0..79 )BASO = 0.05 K/L ( 0.00 – 0.10 )%LYM = 13.3 %%MONO = 10.0 %%NEU = 69.2 %%EOS = 7.2 %%BASO = 0.3 %
“Kitten” – 6 month old DSHLeukonWBC = 17.76 K/L ( 5.50 – 19.50 )LYM = 2.36 K/L ( 0.90 – 7.00 )MONO = 1.78 K/L HIGH ( 0.10 – 0.79 )NEU = 12.29 K/L ( 2.50 – 12.50 )EOS = 1.29 K/L ( 0.10 – 0..79 )BASO = 0.05 K/L ( 0.00 – 0.10 )%LYM = 13.3 %%MONO = 10.0 %%NEU = 69.2 %%EOS = 7.2 %%BASO = 0.3 %
High normal leukocyte count Mild monocytosis
“Kitten” – 6 month old DSHLeukonWBC = 17.76 K/L ( 5.50 – 19.50 )LYM = 2.36 K/L ( 0.90 – 7.00 )MONO = 1.78 K/L HIGH ( 0.10 – 0.79 )NEU = 12.29 K/L ( 2.50 – 12.50 )EOS = 1.29 K/L ( 0.10 – 0..79 )BASO = 0.05 K/L ( 0.00 – 0.10 )%LYM = 13.3 %%MONO = 10.0 %%NEU = 69.2 %%EOS = 7.2 %%BASO = 0.3 %
High normal leukocyte count Mild monocytosis Low normal lymphocytes in
face of excitement !
“Kitten” – 6 month old DSHLeukonWBC = 17.76 K/L ( 5.50 – 19.50 )LYM = 2.36 K/L ( 0.90 – 7.00 )MONO = 1.78 K/L HIGH ( 0.10 – 0.79 )NEU = 12.29 K/L ( 2.50 – 12.50 )EOS = 1.29 K/L ( 0.10 – 0..79 )BASO = 0.05 K/L ( 0.00 – 0.10 )%LYM = 13.3 %%MONO = 10.0 %%NEU = 69.2 %%EOS = 7.2 %%BASO = 0.3 %
High normal leukocyte count Mild monocytosis Low normal lymphocytes in
face of excitement ! High normal eosinophils with
possible “stress”
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Erythron – Blood Film
Leukogram InterpretationNormal leukocyte count
No lymphocytosis in face of excitementProbable underlying glucocorticoid influence (“stress”)
High normal eosinophil count in face of possible glucocorticoid influence (“stress”)
High probability of underlying eosinophilic inflammatory condition
“Kitten” – 6 month old DSHWBC = 17.76 K/L ( 5.50 – 19.50 )LYM = 2.36 K/L ( 0.90 – 7.00 )MONO = 1.78 K/L HIGH ( 0.10 – 0.79 )NEU = 12.29 K/L ( 2.50 – 12.50 )EOS = 1.29 K/L ( 0.10 – 0.79 )BASO = 0.05 K/L ( 0.00 – 0.10 )%LYM = 13.3 %%MONO = 10.0 %%NEU = 69.2 %%EOS = 7.2 %%BASO = 0.3 %HCT = 23.9 % LOW ( 30.0 – 45.0 )RBC = 6.11 M/L ( 5.00 – 10.00 )HGB = 8.5 g/dL ( 8.0 – 15.1 )RETIC = 102.8 K/L%RETIC = 1.7 %MCV = 39.1 fL LOW ( 41.0 – 58.0 )RDW = 22.7 % HIGH ( 17.3 – 22.0 )MCHC = 35.5 g/dL ( 29.0 – 36.0 )MCH = 13.86 pg ( 12.50 – 17.60 )PLT = 905 K/L HIGH ( 175 – 600 )MPV = 16.69 fLPCT = 1.5 %PDW = 17.9 %
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