laboratory for soft tissue and bone-joint pathology

SOFT TISSUE AND BONE-JOINT PATHOLOGYPORNTHIP CHAICHOMPOO

pornthip.chh@mahidol.ac.th

Department of Pathobiology, Faculty of Science, Mahidol University

SCBM342 Systemic pathology

LABORATORY FOR

Examination

• Lecture10points:–Multiplechoice,5choices/Question

• Lab10points:–Multiplechoice,4choices/Question• Identificationofpathology/cellinjury,• Describeanatomicalpathology/histopathologyand• Diagnosis

LABSOFT TISSUE AND BONE-JOINT PATHOLOGY

There are 3 stations: • Bone diseases• Joint diseases• Soft tissue diseases

Post-Quiz (Open books): 10 Questions 30 min

Answers the post-quiz questions

SCBM342 Systemic pathology

40 min / Station

BONE DISEASE

Schuenke M, et.al. Atlas of anatomy.Thieme.2005

OSTEONECROSIS- ANEMIC INFARCT

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

OSTEONECROSIS

Department of Pathobiology, Faculty of Science, Mahidol University

Normal

Ischemia

Aruwajoye OO, et. al.Bone.2013;52:632–9.

OSTEOPOROSIS

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

OSTEOPOROSIS

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

BONE TUMORS- OSTEOMA

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

BONE TUMORS- OSTEOSARCOMA

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

TUMORS- CHONDROSARCOMA

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

JOINT

DISEASE

http://wikipedia.org

RHEUMATIC GRANULOMA

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

RHEUMATOID ARTHRITIS

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

RHEUMATOID ARTHRITIS

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

GOUT

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

รศ.นพ.สรรเพชญ เบญจวงศ์กลุชยั

Tophi : Note the mass containing a chalky substance and having an irregular outer surface.

A TOPHUS is a GRANULOMATOUS response to monosodium urate crystals.

Kuma V, et.al.Robbins&Cotran pathologic basis of disease.8th ed.2010. Saunders

GOUTY NEPHROPATHY

Kuma V, et.al.Robbins&Cotran pathologic basis of disease.8th ed.2010. Saunders

GIANT CELL TUMOR OF TENDON SHEATHJOINT Tumors:

(Giant-cell synovioma - benign tumor of synovial cells)

www.wikipedia.org

A joint disease characterized by inflammation and overgrowth of the joint lining

JOINT Tumors:

PIGMENTED VILLONODULAR SYNOVITIS

www.wikipedia.org

(hemosiderin-laden macrophages)

SOFT TISSUE DISEASES

FAT LIPOMALIPOSARCOMA

NORMAL FAT LIPOMA, encapsulated LIPOSARCOMA, often retroperitoneal

Kuma V, et.al.Robbins&Cotran pathologic basis of disease.8th ed.2010. Saunders

LIPOSARCOMA

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

FIBROUS TISSUENODULAR FASCIITIS (pseudosarcomatous)FIBROMATOSES (plantar, palmar, penile)FIBROSARCOMA

Kuma V, et.al.Robbins&Cotran pathologic basis of disease.8th ed.2010. Saunders

LEIOMYOMA

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

LEIOMYOSARCOMA

©2004 Georg Thieme Verlag. Riede U., Werner M. Thieme medical publishers.2004.

SOFT TISSUE AND BONE-JOINT PATHOLOGY

PORNTHIP CHAICHOMPOO

pornthip.chh@mahidol.ac.th

Department of Pathobiology, Faculty of Science, Mahidol University

SCBM342 Systemic pathology

QUIZ & ANSWER

QUIZ# 1

Bruce A. Fenderson, et. al. Lippincott’s illustrated Q & A review of Rubin’s pathology, 2nd ed.Copyright © 2011 Lippincott Williams & Wilkins

QUIZ# 2

Bruce A. Fenderson, et. al. Lippincott’s illustrated Q & A review of Rubin’s pathology, 2nd ed.Copyright © 2011 Lippincott Williams & Wilkins

QUIZ# 3

Bruce A. Fenderson, et. al. Lippincott’s illustrated Q & A review of Rubin’s pathology, 2nd ed.Copyright © 2011 Lippincott Williams & Wilkins

QUIZ# 4

Bruce A. Fenderson, et. al. Lippincott’s illustrated Q & A review of Rubin’s pathology, 2nd ed.Copyright © 2011 Lippincott Williams & Wilkins

QUIZ# 5

Bruce A. Fenderson, et. al. Lippincott’s illustrated Q & A review of Rubin’s pathology, 2nd ed.Copyright © 2011 Lippincott Williams & Wilkins

QUIZ# 6

Bruce A. Fenderson, et. al. Lippincott’s illustrated Q & A review of Rubin’s pathology, 2nd ed.Copyright © 2011 Lippincott Williams & Wilkins

QUIZ# 7

Bruce A. Fenderson, et. al. Lippincott’s illustrated Q & A review of Rubin’s pathology, 2nd ed.Copyright © 2011 Lippincott Williams & Wilkins

QUIZ# 8

Bruce A. Fenderson, et. al. Lippincott’s illustrated Q & A review of Rubin’s pathology, 2nd ed.Copyright © 2011 Lippincott Williams & Wilkins

QUIZ# 9

Bruce A. Fenderson, et. al. Lippincott’s illustrated Q & A review of Rubin’s pathology, 2nd ed.Copyright © 2011 Lippincott Williams & Wilkins

QUIZ# 10

Bruce A. Fenderson, et. al. Lippincott’s illustrated Q & A review of Rubin’s pathology, 2nd ed.Copyright © 2011 Lippincott Williams & Wilkins