midterm activities breakout discussion
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Mid-Term ProjectsInformation Ecosystem Workshop (PA)
10.10.11
Monday, 10 October 2011
People
• Henrik Seidel
• William Spooner
• Thomas Blackadar
• Ewan Hunter
• Bryn Williams-Jones
• Misha Kapushesky
Monday, 10 October 2011
Mid-Term Project Ideas
• Improving CRO-pharma interaction
• “Common language” tools for integration
• Physical shipping logistics
• Sequence services phase three
Monday, 10 October 2011
CRO-Pharma Environment
• Problem: there are increased costs to CROs and pharma in data round-tripping over QC evaluation rounds
• Short-term Assumption: a common standard can be defined for ELN data interchange
Monday, 10 October 2011
CRO-Environment Mid-Term Project
• Implementation of ELN interchange standard
• Dev’p cloud environment for CRO/pharma
• Identity management and validation
• Timestamp, audit trails, verification
• Secure, validated, trusted (PA-approved)
Monday, 10 October 2011
CRO-Environment Beyond Mid-Term
• Standard for protocol reporting with implementation and servicing
• Look for funding from PA and consider CROs, ELN developers as stakeholders
• ROI
• Better data quality
• Clearer IP ownership
• Lower total cost
• Improve quality control and reproducibility
Monday, 10 October 2011
“Common Language” Tools Mid-Term Project
• Problem: there is no trusted resource for unambiguous resolution of named entities
• Short-term Assumption: an identifier mapping service will be created
Monday, 10 October 2011
“Common Language” Tools Mid-Term Project
• Why? To enable data integration, “disease explorer”-like use cases
• A canonical, trusted, PA-approved repository of vocabularies/ontologies
• Collaborative ontology hosting, development and maintenance environment
Monday, 10 October 2011
“Common Language” Tools Mid-Term Project
• Tools for annotation, tagging and integration of canonical ontologies/vocabularies into QC pipelines, ELN, LIMS, DBs and other systems
• Roles for Pistoia:
• Selection, approval: eg animal models ontol’s
• bring together key stakeholders in academia and industry to result in an SME, non-profit, or a workgroup to help build and maintain service and tools
Monday, 10 October 2011
Physical Shipping Logistics
• Chemicals shipping: standards for labelling, pre- and post-shipping quality control, tracking, servicing
• Workgroup to mandate and approve standards, best practices
Monday, 10 October 2011
Seq Services Phase 3
• Expanding tools and data types
• Expanding to sensitive data: patients, clinical
• Translational applications
• Healthcare
Monday, 10 October 2011
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