obtructive jaundice dr hatem el gohary
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OBSTRUCTIVE JAUNDICE
Dr Hatem EL Gohary
Lecturer of General Surgery
Definition of jaundice
Yellowish discoloration of sclera and skin due to high levels of bilirubin which is manifested above 2 mg/dl.
Physiology of Bilirubin
CausesCalcular: Gall bladder stones passing
through cystic duct to obstruct the common bile duct.
Malignant: - Cancer head of the Pancreas. - Cholangiocarcinoma.
Clinical Picture Jaundice (sclera – Palate) ItchingPain (Cholangitis) Fever (Cholangitis)Dark urine Pale stool.
Investigations
Laboratory: -Total bilirubin and Direct bilirubin(Conjugated) Direct bilirubin more elevated than indirect. - Liver Enzymes elevated. - Hepatitis Markers (A, B & C). - Coagulation Profile (Prothrombin time).
Radiological:-Ultrasound Abdomen showing dilated CBD + stones.- CT and MRI Abdomen showing pancreatic tumor and liver metastasis.- ERCP (Endoscopic retrograde cholangio- pancreatography) diagnostic and therapeutic.
Treatment General: IV fluids – Urine output chart –
Vitamin K –Broad spectrum Antibiotics.
Calcular:- Removal of CBD stones either by ERCP or By Surgical CBD Exploration + Cholecystectomy.
Malignant: Whipple’s Operation.
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