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Regulatory Guideline studies to investigate
developmental effects of glyphosate
Jochen Buschmann
Glyphosate: regulatory studies
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Jochen Buschmann
Rat
Glyphosate: regulatory studies
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Jochen Buschmann
Rat
Glyphosate: regulatory studies
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Jochen Buschmann
Rat
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Jochen Buschmann
Rat
Glyphosate: regulatory studies
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Jochen Buschmann
Rat
Glyphosate: regulatory studies
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Jochen Buschmann
Rat
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Jochen Buschmann
Rat
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Jochen Buschmann
Rabbit
Glyphosate: regulatory studies
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Jochen Buschmann
Mid & high dose: overt maternal toxicity incl. deathhigh embryonic loss
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Jochen Buschmann
Rabbit
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Jochen Buschmann
Rabbit
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Jochen Buschmann
Rabbit, BROOKER et al., 1991
High dose: one maternal death
Elevated post-implantation loss in all treated groups(upper end of hcd), no dose response
Ventricular septal defects:1; 1; 1; 4/4
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Jochen Buschmann
Rabbit
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Jochen Buschmann
Rabbit
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Jochen Buschmann
Rabbit
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Jochen Buschmann
Rabbit
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Jochen Buschmann
Summary:
7 studies in rats, no specific concern
7 studies in rabbits, two in in the grey zone
Does this justify classification and labelling:
cat. 1b / 2 ?
cat. 2 / 3
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Jochen Buschmann
"... misconception that materials can be categorised absolutely as
teratogens or nonteratogens, a belief that is contrary to one of the basic
principles of teratology, namely, that any material may be teratogenic if
given to the right species at the right time at the right dosage."
A. K. Palmer, 1980
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