rieger's syndrome description: a genetically determined syndrome of malformations of the...

Rieger's syndrome

Description:A genetically determined syndrome of malformations of the anterior chamber of the eye and the teeth, combining features of the Axenfeld syndrome with oligodontia. Eye anomalies consist of posterior embryotoxon (an opaque ring at the margin of thecornea), a prominent Schwalbe ring, iris adhesion to the Schwalbe line, hypoplasiaof the anterior stroma of the iris, and occasional glaucoma. Tooth anomalies includeanondontia vera and microdontia.

The Pituitary Gland

www.med.mun.ca/anatomyts/head/pit.htm

kirbylab.duhs.duke.edu/resources.htm

Mouse Development

Gene Gene product Assay

lacZ β-galactosidase Histochemical test

uidA β-glucuronidase Histochemical test

lux Luciferase Bioluminescence

GFP Green fluorescent protein

Fluorescence

Reporter Gene Assay

PITX2-LACZ Staining of mouse embryo day 11

PITX2: bicoid-related transcription factor

Transgenic Mouse (Tg Mouse)

www.beardedman.net/science/genetics/xeno.html

http://www.collaslab.com/article.php?id=18

Chromatin Immunoprecipitation (ChIP) assays are used to evaluate the association of proteins with specific DNA regions.

The WNT Signaling Pathway

http://atlasgeneticsoncology.org/Deep/WNTSignPathID20042.html