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BioLego – A platform for Systems Modeling

BioLego enables biologists analyze their systems quantitatively

• GUI based model building

• Enables biologists test their hypotheses without employing “hardcore” math

• Enables collaboration and knowledge management within an enterprise

Translate Biology into Mathematical Models

Create information-rich networks of interactions

Model Network

Model System

Design experiments for disease evolution, clinical protocols, therapeutic regimens

Parameter Set - Values

Input formats

Simulation Results

Homeostasis Disease

Gain insights into model behaviorby hypothesis generation and testing

Parameter Sensitivity

Compare Results from Multiple Hypotheses

Detect Events of Interest

Steady State Continuation

Analyze and Interpret results with a suite of dynamically linked visualizations

Increase biological understandingby simplifying networks visually

Clone

Collapse

Share Biological Insights and Datawith context-specific annotations

Manage Experiments; Store, Retrieve Results

Experiment Details

References

Develop and Analyze Complex Models… modularly enabling collaboration

Analyze model components in isolation

Integrate Models Seamlessly

Manage Multiple ProjectsTrack model(s) evolution with versioning, user-access control

Track multiple model builders, versions and use history