suffering from osteoporosis? - mathematical modeling of bone remodeling at cellular level yanan wang...
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Suffering from Osteoporosis?-Mathematical modeling of bone
remodeling at cellular level
Yanan Wang31/10/2007
Osteoporosis
How does osteoporosis relate to my work (bone remodeling)?
Bone remodeling cycle at cellular level
Bone remodeling (Coupling)
Significance of bone remodeling
Serving to adjust bone architecture.
Helping to repair microdamage.
Maintaing plasma calcium homeostastis.
Logical structure of the model
Reasons for including PTH
PTH is currently involved in clinical trials.
PTH 1-34 was recently approved by the Food and Drug Administration of America (FDA).
Intermittent vs Continuous
Biomechanical control of bone remodeling
Effect of electromagnetic field on remodeling
Conclusion
The end
Thank you
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