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Transdermal Testing Systems

Dissolution Testing Systems

Physical Testing Systems

By Logan Instruments

LOGAN PRODUCT LINE

Transdermal Testing Systems

By Dr. Luke Lee

LOGAN PRODUCT LINES

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

What products need transdermal testing?

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

Users of Transdermal Systems

Section 1:

Transdermal Diffusion Cells

LOGAN Vertical Cell

Vertical Cell / Franz Cell

Logan Nail Cells

Nail Holder

LOGAN Horizontal Cells / Side By Side

Cells

Logan Cornea

Cells

Horizontal Cells / Side By Side Cells

LOGAN Bubble Free Cell PATENTED

Dry Heat Cells

DHC

SECTION 2:

Filter Paper

Artificial Skin

In-Vitro Skin Models

Filter Paper

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

Artificial Skin – Strat-M membrane

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

Strat-M Membrane

1. Remove the Strat-M Membrane from the plastic bag

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

Strat-M Membrane

2. Place the Strat-M Membrane on the Diffusion Cell

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

Strat-M Membrane

3. Load samples on Strat-M Membrane

Manual Systems

Transdermal Diffusion Cell Systems

LOGAN FDC-6

Transdermal Diffusion Cell Drive Console

Temperature Controller Water Tank

FDC-6 Drive Console

Franz cells

LOGAN SDC-6

Transdermal Diffusion Cell Drive Console ( 6 Side By Side Cells)

LOGAN SFDC-6

Transdermal Diffusion Cell Drive Console ( 3 Vertical Cells & 3 Side By Side Cells)

LOGAN DHC-6T

Dry Heat Transdermal System

LOGAN DHC-6T

Dry Heat Transdermal System

For sampling, the cell support plate lays flat

LOGAN DHC-6T

Dry Heat Transdermal System

For media replacement, the cell support plate tilts to purge the bubbles

Semi- Automated Systems

Transdermal Diffusion Cell Systems

LOGAN FDC-6T

(patents)

A. Bubble Free Cell

B. Tilting Device

C. Manifold system

LOGAN FDC-6T

Semi- Automated System

LOGAN FDC-6T

Semi-Automated Systems

Automated Transdermal

Systems

Transdermal Diffusion Cell Systems

LOGAN SYSTEM 912-6 Automated

Transdermal Diffusion Cell System

SCT-160V Sample Collector System Controller

FDC-6 T Syringe Pump

LOGAN SYSTEM 912-12 Automated

Transdermal Diffusion Cell System

SYRINGE

PUMP

SCT-240V SAMPLE

COLLECTOR

SYSTEM CONTROLLER

FDC-6 DIFFUSION CELL DRIVE CONSOLE

LOGAN SYSTEM 912-24 Automated

Transdermal Systems

DEAR-1200 ONLINE DEGASSING SYSTEM (Optional)

DEAR-100 w/ Vacuum bottle

Hot Plate (Not included)

LOGAN SYSTEM 912

Automated Transdermal Diffusion Cell Sampling

System

AUTOMATED DISSO III-7 SYSTEM Transdermal Patch System

LOGAN SYSTEM 64 Robotic Transdermal System

USP Apparatus 5,6,

USP Apparatus 7

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

Data provided by Merck-Millipore

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08873 USA

Data provided by Merck-Millipore

USP Dissolution Apparatus

By Logan Instruments

USP Apparatus 1,2,5,6,

USP Apparatus 1,2,5,6,

UDT-812GS

Universal Dissolution Tester

With Gas Spring Lift

USP Apparatus 1,2,5,6,

UDT-814

Universal Dissolution Tester

With Power Lift

Year 2014 model

with color touch

screen display

UDT-814-12+2 Universal Dissolution Tester

UDT-804-2L Universal Dissolution Tester

(2L Dissolution Tester)

UDT-804-4L Universal Dissolution Tester

(4L Dissolution Tester)

Physical Calibration Tool Set

Centering Shaft

Wobble Gauge & Stand

Speed Tachometer

Thermometer Timer

SYSTEM 800S with SHIMADZU UV 1600 /1650/1700

Automated Dissolution UV System

SYSTEM U800S with SHIMADZU UV 1600/1650/1700

Automated Dissolution UV System

Method

Product

Sample

SYSTEM 850 BDL For HPLC off line analysis

Automated Dissolution Syringe Pump Sampling System

SYSTEM 860 Automated 3 Speed Zone

Dissolution Sampling System with Center-Point™

Cameras

MDS 600PL

Media Delivery System

The mobile unit brings pre-heated,

degassed media to dissolution testers.

Fills 6 vessels to the same volume

simultaneously.

Media de-aerated by heat, high speed

circulation, filtration and vacuum.

Temperature accuracy controlled to +/- .2 C.

Simultaneously delivers 6 vessels up to

1000 ml within 2 minutes

Detachable Oxygen meter to check oxygen

Printer report for Date, Time, Media Type.

Media Volume, Temperature, Oxygen

Dissolving Rate, pH, etc.

MDS 600

Media Delivery System

MDS-600 Delivery

Manifold

UDT-804

Dissolution Tester

MDS 600T

Media Delivery System

* Table top unit fills media into 6 dissolution vessels

* Six Vessels filled to the same volume simultaneously

* Volume delivered to better than +/-1%

* Deaerated by filtration, circulation, vacuum and heat.

AVC-100 HTP

Automated Vessel Cleaner

• For Validation

• Color Touch Screen Display

• Mobile unit brings cleaner to bath

• Selectable Methods for different products,

* High pressure turbo wash and vacuum

* Media neutralization in waste tank

• Automatic waste discharge

AVC-100

Automated Vessel Cleaner

Wash Head

UDT-804

Dissolution Tester

USP Dissolution Apparatus 3

LOGAN USP DISSO III Classic

Patented

pH 1.7 pH 4.6-6.1

pH 6.5

pH 5.8

pH 6.5-8.0

USP Apparatus 3

For USP Method 3 Tests

In line sampling

Individual vessel

covers

LOGAN AUTOMATED DISSO III-7

SYSTEM

For USP Dissolution Method 7

Tests

USP Apparatus 7

LOGAN DISSO III-7

Release Rate Tester W/ Auto-Sampler

USP Dissolution Method 7

Dry Heat System

LOGAN DISSO III-7 (USP 7) Applications:

Patented !!!!!

LOGAN SYSTEM 7000-24 Automated Hip Stem Test System

LOGAN SYSTEM 7000-24 Automated Hip Stem Test System

LOGAN Fully Automated USP 7

System

LOGAN Tablet Physical Testing

Products

• Disintegration Tester

• Friability Tester

• Hardness Tester

• Tap Density Tester

DST-3/6 Disintegration Tester

•Easy-To-Use input keypad

•Audible end of run signal

•Modular design for 1 to 6

simultaneous tests

• 2 Single in-line layout for

easy viewing of all basket

assembles

•Meets or exceeds all USP

requirements and

specifications

FAB-2S Friability Tester

•As per USP specification

•Adjustable speed at 20-70 rpm

•Test with one or two drums

•Select of counter or timer

•Easy input key pad

•Microprocessor control & LCD

display

FAB-2SP Friability Tester

•As per USP specification

•Adjustable speed at 20-70 rpm

•Test with one or two drums

•Select of counter or timer

•Easy input key pad

•Microprocessor control & LCD

display

•Printer / report center

LOGAN HDT-400L

Automated Hardness Tester For: Hardness / Thickness / Diameter / Weight measurements

LOGAN TAP-2S Automated Tap Density Tester

Meets all current USP, BP, JP

guidelines.

LED Display for TIME or

COUNTER.

Microprocessor Technology

Control System.

Easy To Use Input Keypad.

Modular Design for One or

Two Platforms.

Simultaneous tapping and

rotary motion

LOGAN TAP-2SP Automated Tap Density Tester w/ Printer

Meets all current USP, BP, JP

guidelines.

LED Display for TIME or

COUNTER.

Microprocessor Technology

Control System.

Easy To Use Input Keypad.

Modular Design for One or

Two Platforms.

Simultaneous tapping and

rotary motion

Report printer

Prepared by Logan Instruments THANK YOU!

LOGAN INSTRUMENTS CORP.

19-C Schoolhouse Rd, Somerset New Jersey 08873 USA