validation of rano criteria: contribution of t2/flair assessment in patients with recurrent...

Validation of RANO Criteria: Contribution of T2/FLAIR Assessment in Patients with Recurrent Glioblastoma Treated with Bevacizumab

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Background

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Slide 3

Presented By Raymond Huang at 2014 ASCO Annual Meeting

RANO Criteria

Presented By Raymond Huang at 2014 ASCO Annual Meeting

BRAIN trial (AVF3708g)

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Study design

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Response

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Inter-reader agreement

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Objective Response Rate

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Landmark analysis: Objective response versus Survival

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Progression

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Progression

Presented By Raymond Huang at 2014 ASCO Annual Meeting

PFS: Macdonald vs RANO

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Landmark analysis: Progression vs Overall Survival

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Conclusions

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Future directions

Presented By Raymond Huang at 2014 ASCO Annual Meeting

Acknowledgement

Presented By Raymond Huang at 2014 ASCO Annual Meeting