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 Reference 1. Association of Anae sthetis ts of Gre at Britain & Ireland. Peri-operative care of the elderly 2014. Anaesthesia  2014;  69 (Suppl 1): 81   98. doi:10.1111/anae.12616 A reply Dr Rajamanickam asks a very good ques ti on that is pertinent to our re ce nt guidelines [1]. The ex act transfusion trigger in surgery, in the older patient, is still surrounded by some controver sy, desp ite a rece nt Coch rane re vi ew [2 ]. Th e advi ce from this review is to withhold blood until the haemoglobin concentration re a che s 7080 g.l 1 , which is described as a restrictive transfusion trigger. The review includes 19 stud- ies, involving over 6000 patients, and the in-hospital mortality was lower in those who had a restrictive policy applied. This review is dominated by one study, th e Focu s St ud y [3], which was a rehabilitation study in patients with hip fracture and con- tr ib ut ed 2016 pa ti ents incl uding thos e ov er 50 ye ar s, bu t wi th an average age of around 80 years. All we re randomis ed af te r surg er y. Many of the other included studies invo lved children an d pa ti ents receiving critical care, who are youn- ger than the standard elderly patient. The recent review does mention that there are no trials of transfusion trig- ger s in tho se wit h acute cor ona ry syndromes and that studies are also required in which the trigger is set at 60 g.l 1 [2]. In cont ra st, th er e is ev idence fr om a la rg e ob se rv ati onal st udy [4 ] th at lo oke d at th e eff ect of  ana emi a in old er sur gic al pat ien ts who have had non-cardiac surgery. It sh owed a de tr imental ef fect of  anaemia on outcome from surgery. There are con foundi ng fac tor s at play , as pre- opera tive anaemia can be inv est iga ted and correc ted and is of ten a ma rker of anot he r di s- ea se pr ocess, whil st ac ute bl oo d lo ss ma y just oc cu r in th e ac ut e surgical process. Trans fusio n utili ses a prec ious re so ur ce but cons tan t vi gi la nce aro und the time of sur ger y shoul d be exercise d in th e ol de r pa tient, ma ny of whom ha ve ri sk factor s fo r is ch ae mic he ar t disease. In thos e wi th ri sk fact ors, a hi gh er tri gge r, toward s 90 g.l 1 , may be advisable. R. Grif ths Chair  AAGBI Working Party on  peri-operative care of the elderly Email: [email protected] Previously posted on the  Anaesthe- sia  corr espon denc e webs ite: www. anaesthesiacorrespondence.com. References 1. Association of Anae sth etis ts of Great Britain & Ireland. Peri-operative care of the elderly 2014. Anaesthesia  2014;  69 (Suppl 1): 81   98. 2. Cars on JL, Carles s PA, Hebert PC. Trans- fus ion thr esh old s and other str ate gies fo r gu i di n g a ll o ge n ei c r ed b lo od cel l transfusion.  Coch ran e Data base of Sy st emat ic Re vi ews  2012;  4: CD002042. 3. Carson JL, Ter rin ML, Nove ck H, et al. Libreal or restrictive transfusion in high- risk patients after hip surgery .  New Eng- lan d Jou rnal of Me dic ine  2011;  365: 2453   62. 4. Wu W-C, Schif ftner TI, Henderson WG, et al. Pre oper ative haematoc rit lev els and pos tope rative outc omes in olde r patients undergoing noncardiac surgery.  Journal of the American Medical Associ- ation  2007;  297: 2482   8. doi:10.1111/anae.12617 Trachway and jaw thrust We read with great interest the arti- cle by Lee et al. [1] and agree with the ir con clu sion tha t the mod i ed  jaw thrust is the most effective manoeuvre to improve the laryngeal  view and shorten tracheal intubation time with the Clarus Video System (Trachway  ) intubating stylet (Bio- tro nic Ins tru men t Ent erp rise Ltd ., Tai-C hung, Taiwa n). Eigh t patie nts (Co rma ck and Le han e gra de 3- 4) wh o ha d a fa il ed do ub le -l umen endo trach eal intub ation with con-  ventional direct laryngoscopy (> three attempts) underwent successful intubation using the Trachway intu- batin g style t comb ined with a modi - ed jaw thru st tech niqu e (ope ning the mouth, protruding the mandible forward and elevating both mandib- ular rami). Intubation was successful in all cases at the  rst attempt with- out damage to the tube cuff, episodes of hy pox aemia or obv iou s air way trauma. Altho ugh doubl e-lu men endo- bronchial intubation assisted by the GlideScope (Ve rat hon Me dic al China Sal es, Shang hai , Chi na) has be en re po rt ed in pa ti ents with a dif cul t airway [2, 3], th e wid e bl ad e of th e Gl id eS co pe ma ke s do ub le-l umen intuba tion a ch al - lenge , caus ing dama ge to intra-ora l ti ss ue and teet h in pati ents wi th limited mouth opening. We noticed in Lee et al. s study that the as si stant was fa ci ng the ©  2014 The Association of Anaesthetists of Great Britain and Ireland  285 Correspondence Anaesthesia 2014, 69, 281–290

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  • Reference1. Association of Anaesthetists of Great

    Britain & Ireland. Peri-operative care ofthe elderly 2014. Anaesthesia 2014; 69(Suppl 1): 8198.

    doi:10.1111/anae.12616

    A reply

    Dr Rajamanickam asks a very good

    question that is pertinent to our

    recent guidelines [1]. The exact

    transfusion trigger in surgery, in the

    older patient, is still surrounded by

    some controversy, despite a recent

    Cochrane review [2]. The advice

    from this review is to withhold blood

    until the haemoglobin concentration

    reaches 7080 g.l1, which isdescribed as a restrictive transfusion

    trigger. The review includes 19 stud-

    ies, involving over 6000 patients, and

    the in-hospital mortality was lower

    in those who had a restrictive policy

    applied. This review is dominated by

    one study, the Focus Study [3],

    which was a rehabilitation study in

    patients with hip fracture and con-

    tributed 2016 patients including

    those over 50 years, but with an

    average age of around 80 years. All

    were randomised after surgery.

    Many of the other included studies

    involved children and patients

    receiving critical care, who are youn-

    ger than the standard elderly patient.

    The recent review does mention that

    there are no trials of transfusion trig-

    gers in those with acute coronary

    syndromes and that studies are also

    required in which the trigger is set at

    60 g.l1 [2].In contrast, there is evidence

    from a large observational study

    [4] that looked at the effect of

    anaemia in older surgical patients

    who have had non-cardiac surgery.

    It showed a detrimental effect of

    anaemia on outcome from surgery.

    There are confounding factors at

    play, as pre-operative anaemia can

    be investigated and corrected and

    is often a marker of another dis-

    ease process, whilst acute blood

    loss may just occur in the acute

    surgical process.

    Transfusion utilises a precious

    resource but constant vigilance

    around the time of surgery should

    be exercised in the older patient,

    many of whom have risk factors

    for ischaemic heart disease. In

    those with risk factors, a higher

    trigger, towards 90 g.l1, may beadvisable.

    R. GriffithsChairAAGBI Working Party onperi-operative care of the elderlyEmail: [email protected]

    Previously posted on the Anaesthe-

    sia correspondence website: www.

    anaesthesiacorrespondence.com.

    References1. Association of Anaesthetists of Great

    Britain & Ireland. Peri-operative care ofthe elderly 2014. Anaesthesia 2014; 69(Suppl 1): 8198.

    2. Carson JL, Carless PA, Hebert PC. Trans-fusion thresholds and other strategiesfor guiding allogeneic red bloodcell transfusion. Cochrane Databaseof Systematic Reviews 2012; 4:CD002042.

    3. Carson JL, Terrin ML, Noveck H, et al.Libreal or restrictive transfusion in high-risk patients after hip surgery. New Eng-land Journal of Medicine 2011; 365:245362.

    4. Wu W-C, Schifftner TI, Henderson WG,et al. Preoperative haematocrit levelsand postoperative outcomes in olderpatients undergoing noncardiac surgery.

    Journal of the American Medical Associ-ation 2007; 297: 24828.

    doi:10.1111/anae.12617

    Trachway and jaw thrust

    We read with great interest the arti-

    cle by Lee et al. [1] and agree with

    their conclusion that the modified

    jaw thrust is the most effective

    manoeuvre to improve the laryngeal

    view and shorten tracheal intubation

    time with the Clarus Video System

    (Trachway) intubating stylet (Bio-

    tronic Instrument Enterprise Ltd.,

    Tai-Chung, Taiwan). Eight patients

    (Cormack and Lehane grade 3-4)

    who had a failed double-lumen

    endotracheal intubation with con-

    ventional direct laryngoscopy (>

    three attempts) underwent successful

    intubation using the Trachway intu-

    bating stylet combined with a modi-

    fied jaw thrust technique (opening

    the mouth, protruding the mandible

    forward and elevating both mandib-

    ular rami). Intubation was successful

    in all cases at the first attempt with-

    out damage to the tube cuff, episodes

    of hypoxaemia or obvious airway

    trauma.

    Although double-lumen endo-

    bronchial intubation assisted by the

    GlideScope (Verathon Medical

    China Sales, Shanghai, China) has

    been reported in patients with a

    difficult airway [2, 3], the wide

    blade of the GlideScope makes

    double-lumen intubation a chal-

    lenge, causing damage to intra-oral

    tissue and teeth in patients with

    limited mouth opening.

    We noticed in Lee et al.s study

    that the assistant was facing the

    2014 The Association of Anaesthetists of Great Britain and Ireland 285

    Correspondence Anaesthesia 2014, 69, 281290

  • patient from the left side. In our

    experience, having the assistant

    stand to the side and facing the

    same way as the operator may ease

    the modified jaw thrust manoeuvre

    without causing backache.

    S. W. WuH. T. HsuK. I. ChengKaohsiung Medical UniversityKaohsiung, TaiwanEmail:[email protected]

    No external funding and no com-

    peting interests declared. Previously

    posted on the Anaesthesia corre-

    spondence website: www.anaesthesia

    correspondence.com.

    References1. Lee AR, Yang S, Shin YH, et al. A com-

    parison of the BURP and conventionaland modified jaw thrust manoeuvres fororotracheal intubation using the ClarusVideo System. Anaesthesia 2013; 68:9317.

    2. Hsu HT, Chou SH, Chen CL, et al. Leftendobronchial intubation with a double-lumen tube using direct laryngoscopy orthe Trachway video stylet. Anaesthesia2013; 68: 8515.

    3. Chen A, Lai HY, Lin PC, Chen TY, ShyrMH. GlideScope-assisted double-lumenendobronchial tube placement in apatient with an unanticipated diffi-cult airway. Journal of Cardiothoracicand Vascular Anesthesia 2008; 22:1702.

    doi:10.1111/anae.12612

    Training and assessmentof mask ventilation

    Russo and colleagues found that

    airway skills successfully practised

    on a manikin were not consistently

    effective when transferred to real

    patients [1]. Success rates for venti-

    lation through a facemask were also

    significantly lower than through a

    supraglottic airway device.

    Two methods were used to

    assess mask ventilation. First, con-

    sultant anaesthetists assessed the

    difficulty of ventilation subjectively.

    The grading scale was informal

    and operator-dependent, and pub-

    lished scales on grading of mask

    ventilation were not used [24].

    Second, the success of ventilation

    by novices was measured formally

    using objective criteria: expired car-

    bon dioxide; chest movement

    (none, slight or obvious); and

    expired volume.

    I do not criticise the use of two

    measures: there were sound ethical

    and methodological reasons to

    assess the ease of mask ventilation

    before allowing students to proceed.

    However, it is striking that the mea-

    surement of ventilation performed

    by airway experts was informal and

    subjective, but measurement of

    ventilation by airway novices was

    formal and objective. Surely an

    objective, scientific standard should

    apply to all?

    Perhaps a further implication of

    this study is the need for a uniform

    and objective method to assess

    mask ventilation. The words easy,

    difficult and obvious may be

    comfortably familiar, but they

    remain uncomfortably unscientific.J. NielsenConcord HospitalSydney, AustraliaEmail: [email protected]

    No external funding and no com-

    peting interests declared. Previously

    posted on the Anaesthesia corre-

    spondence website: www.anaesthesia

    correspondence.com.

    References1. Russo SG, Bollinger M, Strack M, et al.

    Transfer of airway skills from manikintraining to patient: success of ventila-tion with facemask or LMA-Supreme bymedical students. Anaesthesia 2013;68: 112431.

    2. Han R, Tremper K, Kheterpal S, et al.Grading Scale for Mask Ventilation.Anesthesiology 2004; 101: 67.

    3. Yildiz TS, Solak M, Toker K. The inci-dence and risk factors of difficult maskventilation. Journal of Anesthesia 2005;19: 711.

    4. Warters RD, Szabo TA, Spinale FG, et al.The effect of neuromuscular blockadeon mask ventilation. Anaesthesia 2011;66: 1637.

    doi:10.1111/anae.12568

    Labelling syringe plungersto reduce medicationerrors

    I was interested to read the letter by

    Webster [1] regarding the colour-

    coding of prefilled syringes and the

    inconsistency of manufacturers to

    comply with the international stan-

    dard. It is well known that syringe-

    swap errors are a significant cause

    of complications in the operating

    theatre [2]. At the start of an oper-

    ating list, emergency drugs are rou-

    tinely drawn up. These are

    commonly stored above the anaes-

    thetic machine for easy access,

    whilst keeping them separate from

    the routine drugs drawn up for each

    case. However, placement of the

    syringes in this way can mean that

    the labels on the barrels of the

    syringes are hidden from view,

    resulting in a higher chance that the

    wrong syringe is selected. I propose

    that, in order to reduce this kind of

    error, the syringes used for emer-

    gency drugs should be clearly

    labelled with printed coloured stick-

    286 2014 The Association of Anaesthetists of Great Britain and Ireland

    Anaesthesia 2014, 69, 281290 Correspondence