anatomy lect 4 neuroanatomy
TRANSCRIPT
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AnatomyAnatomyLecture 4Lecture 4
NeuroanatomyNeuroanatomy
Physician Assistant ProgramPhysician Assistant ProgramMiami Dade CollegeMiami Dade College
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““Imagination is everything. Imagination is everything. It is the preview of life’s It is the preview of life’s coming attractions.”coming attractions.”
Albert Einstein Albert Einstein
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Division of the BrainDivision of the Brain
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Divisions of the BrainDivisions of the Brain
FOREBRAIN (PROSENCEPHALON)TELENCEPHALONDIENCEPHALON
MIDBRAIN (MESENCEPHALON)MESENCEPHALON
HINDBRAIN (RHOMBENCEPHALON))METENCEPHALONMYELENCEPHALON
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FOREBRAIN (PROSENCEPHALON) TELENCEPHALON DIENCEPHALON
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TELENCEPHALONTELENCEPHALONCerebral HemispheresCerebral Hemispheres
Function: Determines Intelligence
Personality Interpretation of Sensory Impulses
Motor Function Planning and Organization
Touch Sensation Location:
The cerebrum is located in the anterior portion of the forebrain.
It is divided into two hemispheres that are connected by the corpus callosum.
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DIENCEPHALONDIENCEPHALONFunction: –Chewing –Directs Sense Impulses Throughout the Body –Equilibrium –Eye Movement, Vision –Facial Sensation –Hearing –Phonation –Respiration –Salivation, Swallowing –Smell, Taste
Location: The diencephalon is located between the cerebral
hemispheres and above the midbrainStructures:
Structures of the diencephalon include the thalamus, hypothalamus, the optic tracts, optic chiasma,
infundibulum, 3rd Ventricle, mammillary bodies, posterior pituitary gland and the pineal gland.
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DIENCEPHALONDIENCEPHALONThe The thalamusthalamus is a major relay center to is a major relay center to
the cortex for all sensations (sight, etc) the cortex for all sensations (sight, etc) except for smell. except for smell.
The The hypothalamushypothalamus controls many controls many functions including hunger, thirst, pain, functions including hunger, thirst, pain, pleasure and the sex drive. pleasure and the sex drive. – Another key function of the hypothalamus is Another key function of the hypothalamus is
to regulate the pituitary gland, which in turn, to regulate the pituitary gland, which in turn, regulates hormonal levels in the body. regulates hormonal levels in the body.
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ThalamusThalamus
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MIDBRAIN (MESENCEPHALON) MESENCEPHALON
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MESENCEPHALONMESENCEPHALONMidbrainMidbrainFunction:
–Controls Responses to Sight –Eye Movement –Pupil Dilation –Body Movement –Hearing
Location: The mesencephalon is the most rostral portion of the brainstem. It is located between the forebrain
and brainstem.
Structures: The mesencephalon consists of the tectum and
tegmentum.
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HINDBRAIN (RHOMBENCEPHALON)) METENCEPHALON
MYELENCEPHALON
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METENCEPHALONMETENCEPHALONPonsPons
Function: Arousal
Assists in Controlling Autonomic Functions Relays Sensory Information Between the
Cerebrum and Cerebellum Sleep
Location: The pons is the portion of the brainstem
that is between the midbrain and the medulla oblongata.
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PonsPons
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METENCEPHALONMETENCEPHALONCerebellumCerebellum
Function: Controls Fine Movement
Coordination Balance and Equilibrium
Muscle Tone Location:
The cerebellum is located just above the brainstem, beneath the occipital lobes at the base of the
skull.
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MYELENCEPHALONMYELENCEPHALONMedulla OblongataMedulla Oblongata
Function: Controls Autonomic Functions
Relays Nerve Signals Between the Brain and Spinal Cord
Location: The medulla oblongata is the lower
portion of the brainstem. It is inferior to the pons and anterior to the
cerebellum.
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BrainstemBrainstemFunction:
–Alertness –Arousal –Breathing –Blood Pressure –Contains Most of the Crainal Nerves –Digestion –Heart Rate –Other Autonomic Functions –Relays Information Between the Peripheral Nerves and Spinal Cord to the Upper Parts of the Brain
Location: The brainstem is located at the juncture of the cerebrum
and the spinal column. It consists of the midbrain, the pons and the medulla oblongata.
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Headaches and Facial PainHeadaches and Facial Pain
Benign vs. pathologicBenign vs. pathologic
TumorTumor
NeuralgiaNeuralgia
OtalgiaOtalgia
odontalgiaodontalgia
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Basal Ganglia and CerebellumBasal Ganglia and Cerebellum The basal ganglia and cerebellum are large collections The basal ganglia and cerebellum are large collections
of nuclei that modify movement on a minute-to-minute of nuclei that modify movement on a minute-to-minute basis. basis.
Motor cortex sends information to both, and both Motor cortex sends information to both, and both structures send information right back to cortex via the structures send information right back to cortex via the thalamus. thalamus. – (Remember, to get to cortex you must go through thalamus.) (Remember, to get to cortex you must go through thalamus.)
The output of the cerebellum is excitatory, while the The output of the cerebellum is excitatory, while the basal ganglia are inhibitory. basal ganglia are inhibitory.
The balance between these two systems allows for The balance between these two systems allows for smooth, coordinated movement, and a disturbance in smooth, coordinated movement, and a disturbance in either system will show up as movement disorders either system will show up as movement disorders
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HippocampusHippocampus located inside the temporal lobe (one in located inside the temporal lobe (one in
each side of the brain). each side of the brain). It forms a part of the limbic system and It forms a part of the limbic system and
plays a part in memory and spatial plays a part in memory and spatial navigation. navigation.
Affected in:Affected in:– Alzheimer's diseaseAlzheimer's disease– HypoxiaHypoxia– EncephalitisEncephalitis
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Pg 913Pg 913
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Pg 909Pg 909
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Dura mater (reflections)Dura mater (reflections)1.1. Crista galli Crista galli
2.2. Falx cerebri Falx cerebri
3.3. Sinus sagittalis inferior Sinus sagittalis inferior
4.4. Incisura tentorii - Tentorial incisure Incisura tentorii - Tentorial incisure
5.5. Sinus rectus Sinus rectus
6.6. Confluens sinuum Confluens sinuum
7.7. Tentorium cerebelli Tentorium cerebelli
8.8. Sinus petrosus superior Sinus petrosus superior
9.9. Sinus sphenoparietalis Sinus sphenoparietalis
10.10. Diaphragma sellae Diaphragma sellae
11.11. Arteria carotis interna Arteria carotis interna
12.12. Nervus opticus Nervus opticus
13.13. Foramen magnumForamen magnum
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Head InjuryHead Injury
10% of Deaths10% of Deaths
LOCLOC
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In 1848, Phineas T. In 1848, Phineas T. Gage,Gage,
during railroad during railroad construction a construction a charge exploded charge exploded and the tamping and the tamping rod when through rod when through his frontal skull, his frontal skull, destroying his destroying his prefrontal cortex. prefrontal cortex. He survived! He survived! Regaining his Regaining his physical health in physical health in a few weeks. a few weeks. However, his However, his personality personality changed changed dramatically." dramatically."
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Acute cerebral Acute cerebral contusionscontusions
Two weeks after Two weeks after injuryinjury
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Pg 920Pg 920
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Epidural hematoma. Usually s/p head trauma.
Brief +LOC, followed by lucid period. Then drowsy/coma/death.
A well-defined biconvex collection of blood (arrows) compresses the left cerebral hemisphere. There is inward displacement of the grey-white junction (arrowheads) and slight rightward displacement of the left lateral ventricle.
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Subdural hematomaSubdural hematoma::
a a concaveconcave collection of collection of venous blood between venous blood between the dura and the arachnoidthe dura and the arachnoid – (resulting from tears of the bridging veins that (resulting from tears of the bridging veins that
extend from the subarachnoid space to the dural extend from the subarachnoid space to the dural venous sinuses.)venous sinuses.)
– Patients with cortical atrophy, such as alcoholics and Patients with cortical atrophy, such as alcoholics and the elderly, are more susceptible to subdural the elderly, are more susceptible to subdural hematoma formation when undergoing acceleration-hematoma formation when undergoing acceleration-deceleration forces during deceleration forces during head traumahead trauma. .
– After 2 weeks, patients are defined as having a After 2 weeks, patients are defined as having a chronic subdural hematoma, which appear chronic subdural hematoma, which appear hypodense on a CT scan.hypodense on a CT scan.
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Large acute subdural hemorrhage (arrows) revealed by CT scan at the level of the lateral ventricles. The hemorrhage has resulted in midline shift, with marked compression and displacement of the right ventricle (arrowheads). Because of the brain distortion and obstruction of CSF outflow, the left lateral ventricle is dilated (wavy arrows).
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Right subdural hemorrhage revealed by MRI. The high intensity (white) hemorrhage has dissected under the temporal lobe, and the midline has been displaced to the left. Note the skull fracture overlying the hematoma.
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Chronic bilateral subdural hematoma. This skull X-ray shows areas of calcification adjacent to the inner table of both parietal bones (arrows). The diagnosis was confirmed by CT.
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Subarachnoid hemorrhageSubarachnoid hemorrhage:: – results from the disruption of subarachnoid vesselsresults from the disruption of subarachnoid vessels– presents with presents with blood in the cerebrospinal fluidblood in the cerebrospinal fluid. . – Not a space occupying lesion, “pero” can lead to Not a space occupying lesion, “pero” can lead to
increased ICP and acute hydrocephalusincreased ICP and acute hydrocephalus– Patients may complain of Patients may complain of headache, photophobia, headache, photophobia,
and have mild meningeal signsand have mild meningeal signs..– Noncontrast CT is diagnostic in most cases (95%)Noncontrast CT is diagnostic in most cases (95%)– If CT is neg, but clinical suspicion is strong do LPIf CT is neg, but clinical suspicion is strong do LP– ““Worst HA of my life”Worst HA of my life”– ““Thunder-clap HA” Thunder-clap HA” – Sudden OnsetSudden Onset
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Subarachnoid Subarachnoid HemorrhageHemorrhage
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Diffuse or focally increased ICP:Diffuse or focally increased ICP:– can result in herniation of the brain at several can result in herniation of the brain at several
locations.locations.
Transtentorial (uncal) herniation:Transtentorial (uncal) herniation:– occurs when the uncus of the temporal lobe occurs when the uncus of the temporal lobe
is forced through the tentorial hiatus causing is forced through the tentorial hiatus causing compression of the ipsilateral third cranial compression of the ipsilateral third cranial nerve and the cerebral peduncle.nerve and the cerebral peduncle.
– This leads to a dilated ipsilateral pupil and This leads to a dilated ipsilateral pupil and contra- lateral hemiparesis.contra- lateral hemiparesis.
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Post Spinal Tap HeadachePost Spinal Tap Headache
MeningitisMeningitis
Epidural Nerve Block (OB)Epidural Nerve Block (OB)
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ReviewReview
A.Subarachnoid ?B.Subdural ? C.Epidural ?
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ReviewReview
Subdural
Epidural Subarachnoid
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pg1125pg1125
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pg1128pg1128
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3 3 (SO (SO 44 LR 6) LR 6)
Sympathetic Sympathetic stimulation of stimulation of α1-receptorsα1-receptors
Parasympathetic Parasympathetic axons axons
circular muscle
radial muscle
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Five basic tastesFive basic tastes
BitternessBitterness
SaltinessSaltiness
SournessSourness
SweetnessSweetness
UmamiUmami
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pg1152pg1152
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Horner’s SyndromeHorner’s Syndrome– Lesion of Cervical Sympathetic TrunkLesion of Cervical Sympathetic Trunk– PtosisPtosis– MiosisMiosis– AnhydrosisAnhydrosis
Carotid Sinus MassageCarotid Sinus Massage
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StrokeStroke
Ischemic Vs. HemorrhagicIschemic Vs. Hemorrhagic
CVA vs TIACVA vs TIA
AneurysmAneurysm
Berry @ Basilar/Posterior cerebral Berry @ Basilar/Posterior cerebral arteryartery
SAHSAH
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'Excellence is an art won by training and habituation. We do not act rightly because we have virtue or excellence,
but rather we have those because we have acted rightly. We are what we repeatedly do. Excellence, then, is not an
act but a habit.' AristotleA journey of a thousand miles begins with a single step. A journey of a thousand miles begins with a single step.
Lao TsuLao Tsu ““I find that the harder I work, the more luck I seem to I find that the harder I work, the more luck I seem to
have”.have”. Thomas JeffersonThomas Jefferson
Self conquest is the greatest of victories.Self conquest is the greatest of victories. PlatoPlato
““Imagination is everything. It is the preview of life’s Imagination is everything. It is the preview of life’s coming attractions.”coming attractions.”
Albert EinsteinAlbert Einstein