anatomy of a lactococcal phage stephen mc grath 2006 proposed model of tuc2009 morphogenesis

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ANATOMY OF A ANATOMY OF A LACTOCOCCAL PHAGE LACTOCOCCAL PHAGE Stephen Mc Grath 2006 Stephen Mc Grath 2006 Proposed Model of Proposed Model of Tuc2009 Tuc2009 Morphogenesis Morphogenesis

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Page 1: ANATOMY OF A LACTOCOCCAL PHAGE Stephen Mc Grath 2006 Proposed Model of Tuc2009 Morphogenesis

ANATOMY OF A ANATOMY OF A LACTOCOCCAL PHAGELACTOCOCCAL PHAGE

Stephen Mc Grath 2006Stephen Mc Grath 2006

Proposed Model of Proposed Model of Tuc2009 MorphogenesisTuc2009 Morphogenesis

Page 2: ANATOMY OF A LACTOCOCCAL PHAGE Stephen Mc Grath 2006 Proposed Model of Tuc2009 Morphogenesis

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Tail tube Initiator complex BaseplatesWhiskers

MTP2009

gpGT2009

TMP2009

Dit2009

Tal2009

BppU2009

BppA2009

BppL2009

NPS2009

Stephen Mc Grath 2006Stephen Mc Grath 2006

Page 3: ANATOMY OF A LACTOCOCCAL PHAGE Stephen Mc Grath 2006 Proposed Model of Tuc2009 Morphogenesis

MTP2009

gpGT2009

TMP2009

Dit2009

Tal2009

BppU2009

BppM2009

BppL2009

NPS2009

Initiator complex formation BppU2009

BppA2009

BppL2009

Baseplates assemble on initiator complex

gpGT facillitates tail tube polymerisation

Tail length determined by TMP2009

Stephen Mc Grath 2006Stephen Mc Grath 2006

Page 4: ANATOMY OF A LACTOCOCCAL PHAGE Stephen Mc Grath 2006 Proposed Model of Tuc2009 Morphogenesis

Assembled virion heads

Collar and whisker structure (NPS2009)

Assembled virion tails

Collar and whiskers attached to heads

Mature Tuc2009 virion completed upon attachment of tails to primed heads

Stephen Mc Grath 2006Stephen Mc Grath 2006