Office of Research

ANIMAL CARE AND ETHICS COMMITTEE

Return on Animal Use

The Animal Research Regulation 2010 requires accredited research establishments and animal research licence holders to provide information on the numbers of animals used in research each year. The records provide the Animal Research Review Panel with a broad overview of animal research and are collated for inclusion in the Panel's Annual Report which is tabled in Parliament. While essential for the panel's record keeping, the identity of respondents is considered confidential and will not be published.

Please note the following information:

This report is required annually for the calendar year or once the project is completed ordiscontinued.

Please use plain English. Assume that your audience has either little scientific or medicalbackground, or no specialist knowledge of your area of research.

All questions must be answered (even if your response is "Not Applicable"), and the report mustbe typed. Handwritten reports will not be accepted.

Students are reminded that Academic Sanctions will be applied if this report is not received bythe Animal Care and Ethics Committee on completion of the project.

Submit this report by email to: animalethics.lismore@scu.edu.au ATTENTION MAC USERS: This form will be corrupted if opened in Preview.

PART 1: ADMINISTRATIVE DETAILS

ACEC Authority reference number:

Name of authority holder:

Project title:

Email:

Phone Number:

Select from the following options the type of report you are providing:

Renewal (Select if the current Animal Research Authority approval period is less than 12 months in duration and your project is ongoing for at least another 12 months. Note: Projects needing renewal for less than 12 months please submit a Change of Protocol Form)

Completion Report Completion Date:

Discontinued (Select this option if the project has been stopped. You will need to provide reasons in Section C of this form.)

Discontinued date:

(i) Species and fatalities: enter codes as per Appendix

Animal Species (refer to

Appendix for appropriate code)

Total number approved

Number of animals

used (including monitored)

Number of fatalities

Purpose (refer to

Appendix for appropriate

code)

Procedure (refer to

Appendix for appropriate

code)

Additional Comments (reason for

fatality)

State or country where research was

undertaken (Please list for each species

individually)

(ii) Explain below if your report shows: 1. A discrepancy between approved and actual number of animals used. Explain why.

2. Fatalities and provide detail about any modifications to methodology to prevent this from happening again .

The Government requires that a report must be submitted to both the Animal Care and Ethics Committee and the Project Supervisor on completion of any animal research project, containing information on species and exact numbers that are caught or monitored, as well as any fatalities and suspected reasons for the fatality.

NUMBER OF ANIMALS APPROVED AND USED IN RESEARCH PART 2:

ANIMAL CARE AND ETHICS COMMITTEE Return on Animal Use

Mandatory for species S31 Domestic Cats and S32 Domestic Dogs – refer to Appendix for

appropriate code

Office of Research

ANIMAL CARE AND ETHICS COMMITTEE Return on Animal Use

The Code of Practice for the Care and Use of Animals for Scientific Purposes states, “… the need in scientific and teaching activities to consider the Replacement of animals with other methods, the Reduction in the number of animals used, and the Refinement of techniques used to reduce the adverse impact on animals”. In relation to this statement, provide responses to all the following questions.

(i) Replacement:

Provide details of any non-animal alternatives that you have used in place of live animals during the conduct of the project, to achieve your specific project aims:

(ii) Refinement:

Provide details of any methods you have introduced during the conduct of this project, that have reduced any pain or distress experienced by the animals:

(iii) Reduction:

Provide details of any methods you have introduced during the conduct of this project that have reduced the number of animals used:

SECTION B: REPLACEMENT, REFINEMENT AND REDUCTION

(iv) Problems or adverse events:

If an unexpected adverse event occurred during the project, indicate whether you have submitted an unexpected adverse events form to the ACEC?

Yes NoIf Yes, date submitted:

Outcome: (Tick all that apply)

1. CoP requested and approved

2. under ACEC review

3. Research postponed / cancelled

Progress to date or outcome in the case of completed research:

Provide details here (i.e. describe the progress or outcome including how animal well-being was monitored throughout the project. (Refer to Clause 1.1 [v] and 1.18–1.30)

DECLARATIONSECTION D:

SECTION C: RESEARCH OUTCOMES

In accordance with the legislation, I declare to the Southern Cross University Animal Care and Ethics Committee that the project described in this report:

Will continue and if applicable, a renewal request has been indicated above.

Has been discontinued.

Study has not commenced.

Is completed.

Unless otherwise stated, the treatment and disposal of animals used for the project has been in accordance with the approved protocol.

Name of Chief Investigator:

Signature: Date:

To submit this form, you must: Add your electronic signature and date (above) and use SUBMIT to send to

animalethics.lismore@scu.edu.au

ANIMAL CARE AND ETHICS COMMITTEE Return on Animal Use

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Appendix – Codes Column 1 Options for Animal Species Codes: Lab Animals 01 Mice Primates 34 Marmosets

02 Rats 35 Macaques 03 Guinea Pigs 36 Baboons 04 Rabbits 37 Other Primates 05 Hamsters 06 Ferrets Native Animals 38 Macropods 07 Other Lab mammals (not primates) 39 Possums and Gliders

40 Native rats and mice Domestic Mammals 08 Sheep 41 Dasyurids

09 Cattle 42 Wombats 10 Pigs 43 Koalas 11 Horses 44A Monotremes 12 Goats 44B Bandicoots 14 Deer 44C Bats 31 Cats 44D Other Native Mammals 32 Dogs 44E Seals 33 Other Domestic Mammals 44F Whales and dolphins

Birds 13 Poultry Exotic Feral Mammals 45 Camels 16 Exotic Captive 46 Cats 17 Exotic Wild 47 Cattle 18 Native Captive 48 Goats 20 Native Wild 49 Hares 21 Other Birds 50 Horses

51 Mice Aquatic Animals 23 Fish 52 Pigs

23A Cephalopods (not mandatory to report) 53 Rabbits 23B Crustaceans (not mandatory to report) 54 Rats

55A Dingo/Wild Dogs Amphibians and Reptiles 24 Amphibians 55B Foxes

27 Lizards 55C Other exotic feral mammals 28 Snakes 29 Turtles and Tortoises Exotic Zoo Animals 56 Exotic zoo animals 30 Other Reptiles

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Column 5 Options for Purpose Code Stock Breeding 1 Breeding projects to produce new teaching or

research stock. Including animals used to produce progeny and breeders or progeny culled in the process. The final progeny themselves will be counted under the project in which they go on to be used.

Research animal management or production

6 Aims to produce improvements in domestic or captive animal management or production.

Stock Maintenance 2 Normal stock animals kept mainly for commercial production, but occasionally used in research – ie.they are only counted in the project where they are used for teaching/research.

Research environmental study

7 Aims to increase the understanding of animals’ environment or their role in it. E.g. Studies to determine population levels and diversity. Techniques may be observation, radio tracking or capture and release.

Education 3 For the achievement of educational objectives and to pass on established knowledge to others. E.g. Interactive or demonstration class

Production of biological products

8 For production of products other than milk, meat, eggs, leather, fur, etc. (e.g. Blood donation to produce microbiological media, production of commercial anti-serum, drugs, Quality assurance testing of drugs. Excludes animals for Purpose 9.

Research human or animal biology

4 Aims to understand the structure, function and behaviour of animals (including humans) and processes involved in physiology, biochemistry and pathology

Diagnostic procedures 9 Animals used directly as part of diagnostic process. • Inoculation of day old chicks with ND Virus to

determine virulence• Blue-green algae toxicity testing• Water supply testing using fish

Research human or animal health and welfare

5 Aims to produce improvements in the health and welfare of animals, including humans.

Regulatory product testing 10 Use for testing products required by regulatory authorities (e.g. APVMA) eg.Pre-registration efficacy or toxicity testing of drugs and vaccines

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Column 6 Options for Procedure Code Observation Involving Minor Interference

1 No interaction with animals, or with interaction the animal’s welfare is not compromised any more than normal handling, feeding etc. No pain and suffering.

Minor Physiological Challenge

6 Animal remains conscious for some or all of the procedure with interference in the animal's physiological or psychological processes. May only cause a small degree of pain/distress or any pain/distress is quickly and effectively alleviated.

Animal Unconscious Without Recovery

2 Animal rendered unconscious under controlled conditions. Little or no pain or distress. Capture methods not required. Pain minor or brief and not requiring analgesia. Procedure on unconscious animal then euthanised without regaining consciousness.

Major Physiological Challenge

7 Animal remains conscious for some or all of the procedure. Interference with the animal's physiological or psychological processes causes a moderate or large degree of pain/distress which is not quickly or effectively alleviated.

Minor Conscious Intervention

3 Minor procedures that don’t require anaesthesia or analgesia. Usually not requiring pain relief. Some distress during trapping and handling.

Death as an Endpoint 8 Only applies in rare cases where the death of the animal is a planned part of the procedures and animals die but are not euthanased. E.g.Lethality testing (including LD50, LC50). If predictive signs of death are identified and euthanasia has been carried out BEFORE significant suffering occurs, may place procedure in category 6 or 7.

Don’t use for: death by natural causes or that were accidental, animals euthanised as part of project, if something goes wrong, or for euthanasing animals for dissection or museum specimens. These procedures should be identified as Category 2.

Minor Surgery with Recovery

4 Animal rendered unconscious with little pain or distress. Minor procedure (e.g. Cannulation or skin biopsy) carried out and animal allowed to recover. Pain relief given. Field capture using chemical restraint included.

Production of genetically modified animals

9 Includes ALL animals used in GM production other than the final progeny which are used in a different category of procedure.

Major Surgery with Recovery

5 Animal is rendered unconscious with little pain or distress as possible. A major procedure (e.g. abdominal/orthopaedic surgery) carried out and the animal allowed to recover. Post-operative pain usually considerable and at a level requiring analgesia.

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Fate of Animal Codes: Fate Code Fate of Animal description F1 Retained in project

This is where the project is ongoing and the animal will remain in the project in the next reporting year. F2 Retained for use in other projects or supplied to another establishment / individual for research

This is where the animal is kept by the establishment / individual for use in other research projects or supplied to another establishment / individual for use in research. F3 Retired from research and kept by the establishment / individual

This is where the animal is kept by the establishment / individual in retirement with no further plans for use in research. F4 Privately (non-research) owned and remained with owner

This is where the animal is privately owned and remains with the owner. Examples:

• Animal presented to veterinary clinic for treatment and participates in clinical trial• Behavioural study with privately owned companion animals

F5 Rehomed (as companion animal to private (non-research) home or rehoming organisation) This is where the animal is rehomed as a companion animal to a private (non-research) home or to a rehoming organisation with the consent of the rehoming organisation.

F6 Euthanased or died related to the project This is where the animal is required to be euthanased as an integral part of the research project, or is euthanased or dies during the project as a consequence of the project procedures.

F7 Euthanased or died unrelated to the project This is where the animal is euthanased or dies during the project for reasons unrelated to the project. Example:

• Animal in long-term food palatability trial euthanased due to unmanageable osteoarthritis

F8 Euthanased because unsuitable to be rehomed This is where the animal is no longer required for research and is euthanased on the basis of an assessment that the animal is unsuitable for rehoming. Reasons the animal is unsuitable for rehoming may include physical, behavioural and biosecurity factors. Examples:

• Animals with unmanageable health conditions causing discomfort or distress• Animals that have problem behaviours that are unable to be addressed through rehabilitation• Animals that could pose a biosecurity risk to other animals, people or the environment• Animals that are genetically modified

F9 Euthanased because unable to find a suitable home This is where the animal is no longer required for research and is assessed as suitable for rehoming, but is euthanased because a suitable home is unable to be found.

F10 Remain free living in the wild or released to the wild This is where the animal is free living and remains in the wild (including where the animal is captured and released) and where the animal is released to the wild. Examples:

• Wildlife fauna surveys• Native animal captive breeding and monitored release programs