animals in research donald b. casebolt director, department of animal resources
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Animals in Research Donald B. Casebolt Director, Department of Animal Resources. Objectives. Responsibilities of the institution Responsibilities of the principal investigator. - PowerPoint PPT PresentationTRANSCRIPT
Animals in Research
Donald B. Casebolt
Director, Department of Animal Resources
Objectives
Responsibilities of the institution Responsibilities of the principal investigator
“The development of knowledge necessary for the improvement of
the health and well-being of humans as well as other animals requires in vivo experimentation
with a wide variety of animal species.”
(United States Office of Science and Technology Policy, 1985)
Federal Laws
Animal Welfare Act US Department of Agriculture
Health Research Extension Act National Institutes of Health
Office of Laboratory Animal
Welfare
Similarities of Two Laws
Institutional Official Institutional Animal Care and Use Committee Program of veterinary care Training of personnel
“Enforced
Self-Regulation”
AAALAC Accreditation
IACUC Membership
Scientist Veterinarian with training and/or experience in
laboratory animal medicine Nonscientist At least one member not affiliated with the
institution (public member)
IACUC Responsibilities
Review the programs of animal care and use Inspect animal facilities and procedure areas Approve, require modifications prior to
approval, or withhold approval of animal use protocols
Approve any changes to animal use protocols The IACUC is authorized to suspend a
protocol
Principal Investigator Responsibilities
Preparation and submission of Animal Use Protocols
Modifications to protocols Justification of animal species and numbers Training of personnel in appropriate methods Occupational health and safety of personnel Avoidance of animal pain and distress Development of humane endpoints Animal euthanasia methods
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Training
Species-specific Protocol-specific Web based and hands-on
Questions?