anis presentation-multiple sclerosis imaging

8/17/2019 ANIS Presentation-MULTIPLE SCLEROSIS IMAGING

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OVIDIUS UNIVERSITY OF CONSTANŢAFACULTY OF MEDICINE

MEDICAL IMAGING

OF DEMYELINATING DISEASES; WITH

EMPHASIS ON MULTIPLE SCLEROSIS

Thesis Presentation b !Anis Etteha"#$ha%h

SCIENTIFIC COORDINATOR: Dr. Baz

Radu-Octavian


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DEFINITION

A demyelinating disease is an "isease a&&e'tin% the

'entra$ ner(o#s sste)* +hi'h res#$ts in "a)a%e to the

)e$in sheath o& ne#rons,

Multiple sclerosis (MS)* is an in&$a))ator "isease in +hi'hthe ins#$atin% 'o(ers o& ner(e 'e$$s in the brain an" s-ina$ 'or"

are "a)a%e", This "a)a%e "isr#-ts the abi$it o& -arts o& the

ner(o#s sste) to 'o))#ni'ate,

MRI #se" to in(esti%ate the bo" in both hea$th an" "isease,It #ses )a%neti' &ie$"s an" ra"io +a(es to &or) i)a%es o&

the bo" * +i"e$ #se" &or )e"i'a$ "ia%nosis* sta%in% o&

"isease an" &o$$o+.#- +itho#t e/-os#re to ioni0in% ra"iation,


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MATERIAL AND METOD

,

. 1 -atients &ro) Constanta* Ro)ania !

. 2 Ma$e* 3 Fe)a$e

. A%e ran%e! 24.56

. Metho" o& In(esti%ation! MRI 7T8.T2 Se9#en'in%:

. Ga"o$ini#) enhan'e)ent

P#r-ose +as to a--re'iate the "ia%nosis an" &o$$o+.#-*

b +a o& )e"i'a$ i)a%in%* o& these )#$ti-$e s'$erosis -atients


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Fig.1 Sa%itta$ -$ane i)a%e*hi%h$i%htin% h-erintense

$esions* (isib$e in s-ina$

area* in 56 ear o$" &e)a$e

-atient,

S!INAL LESIONS


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S!INAL LESIONS

Fig.2 31 ear o$" )a$e in9#estion, Note s-ina$

h-erintense $esions,


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DAWSON’S FINGERS

The McDonald ‘s Critria* +hi'h sho+ ra"io$o%i' e(i"en'e o& $esions at "i&&erentti)es an" in "i&&erent areas* is the )ost 'o))on$ #se" )etho" o& "ia%nosis,

One o& the )ost i)-ortant si%ns o& the M'Dona$"s Criteria in'$#"e ;

Da!son"s #in$rs % &eat#res "e-i'tin% "e)e$inatin% -$a9#es thro#%h the

'or-#s 'a$$os#)* arran%e" at ri%ht an%$es a$on% )e"#$$ar (eins

Fig. 3 Da+sons Fin%ers '$ear$ (isib$e in -eri'a$ossa$ area


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DAWSON’S FINGERS

Fig.4 : T2 a/ia$ -$ane i)a%e* sho+in% +hite)atter $esions* in 31 ear o$" )a$e -atient, Note

the (isib$e -resen'e o& Da+sons Fin%ers,


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DISSEMINATION IN S!A"E

Another i)a%in% 'riterion &or the "ia%nosis o& MS ; Disse)ination in S-a'e

Fig.5:


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Another i)a%in% 'riterion &or the "ia%nosiso& MS ; Disse)ination in Ti)e

Fig# $ MS -ro%ression as seen

o(er 5 ears, Note the"isse)inations in ti)e


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%enerali&ed In'lammatory Actiity

Fig.7: M#$ti-$e enhan'in% $esions in 24 ear o$" )a$e,Sho+in% Ga"o$ini#) enhan'e)ent


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%enerali&ed In'lammatory Actiity

Fi% = ! $esions in %enera$ise" +hite an" %re )atter

7Di&sion :,


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"ON"LSION

MRI te'hni9#e re)ains the best i)a%isti' )etho" to -ositi(e$

"ia%nose MS* better than CT s'an or an other ra"io$o%i'a$too$,>e'a#se !.Mini)a$ ioni0in% ra"iation #n$i?e @.ra thereb )a?in% it sa&e

&or -re%nant -atients.In'rease" "etai$e" "ia%nosti' i)a%isti' in&or)ation other+ise

#na(a$iab$e #sin% other )etho"s.>est in "ete'tin% "isse)ination in ti)e es-e'ia$$ #sin%

%a"o$ini#) enhan'e)ent

D#e to the abo(e a"(anta%es o& MRI i)a%isti' #se

the "ia%nosis o& MS has in'rease" +ithin re'ent -ast* this

in s-ite o& the &a't that MS si%ns an" s)-to)s are (er

si)i$ar to those o& other "e)e$inatin% "iseases,

The -atients o& Constanta* Ro)ania &or the -ast 2,1 ears ha(e

been re'ei(in% o-ti)a$ treat)ent* &o$$o+.#- an" a''o)-ani)ent*

"#e to "etai$e" an" a''#rate i)a%in% o& the -ro%ression o& their

"isease,


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THANS FOR YOUR

TIME AND ATTENTION

anis presentation-multiple sclerosis imaging

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