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1 August 1966 Vol 65 No 2gt

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Ann I ntern Med 1 August 196665(2)377-381 Text Size A A A

Editorials | 1 August 1966

Er ythropoietin and Erythropoiesis[+] Article and Author Information

Investigations of the mechanism of regulation of red cell production have received their impetus in recent

years from the classical experiments of Reissman (1) which clearly established the existence of a humoral

erythropoietic factor and the studies of Jacobson Plzak Fried and Goldwasser (2) and Jacobson Gurney

and Goldwasser (3) which made available a series of simple sensitive procedures for its bioassay In the

last 10 years there has been rapid progress in understanding of the biochemical nature mechanism of

action and role in both physiological erythropoiesis and abnormal states of red cell formation of

erythropoietin the hormonal regulator of

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