annual report · north east and north cubria & huber east midlands eastern c partners health...

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ANNUAL REPORT2017 - 2018



CONTENTS

Our vision is to be a recognised

international leader in

accelerating innovation that

transforms citizens’

health and wellbeing.

Foreword 02

AboutHealthInnovationManchester 04

HealthInnovationManchesterjourney 05

Nationalimpact 07

Clinicalresarchexcellence 09

Informaticsandanalytics 11

Healthandimplementation 13

Deliveryprogrammes 16

IndustryPartnerships 23

Industryandwealth 25

EducationandTraining 27

Publicinvolvement&engagement29

OurBoard 31

FinancialReport 33


FOREWORD

Positioning Greater Manchester

as an internationally renowned

location for life science, med-tech

and digital healthcare research and

innovation.

WearedelightedtobringyouthefirstannualreportfromHealthInnovationManchester.

2017/2018hasbeenayearofmajortransitionaswebroughtManchesterAcademicHealthScienceCentre(MAHSC)andGreaterManchesterAcademicHealthScienceNetwork(GMAHSN)underthesingleumbrellaofHealthInnovationManchesterinOctober2017.

Despitethechallengesofamajortransition,wehavecontinuedtosuccessfullymaintaintractiononallexistingprogrammes.ThishasbeeninparalleltosecuringanewAcademicHealthScienceNetworklicenceagreementfromNHSEngland,andpreparingforthere-accreditationasanAcademicHealthScienceCentre

Inadditionto‘businessasusual’wehavealsomadesignificantinroadsincreatingkeyinfrastructure,governanceanddecision-makingmechanismscriticaltoinjectinginnovationintothehealthandsocialcaresystem.

ThishasincludedtheformationofthenewHealthInnovationManchesterBoardwhichdrawsonexpertisefromacrosstheNHS,socialcare,industryandacademia;worktoestablishtheInnovation,MonitoringandPrioritisationCommittee(IMPC),whichwillprioritiseandoverseetheinnovationandimprovementworkprogramme,thedevelopmentoftheinnovationpathwaytosimplifythelandscapeforindustryinnovatoions,andpavedthewayfordigitalinteroperabilityandinnovationhubsthatwillimprovethecareweprovidetopatientsnowandinthefuture.

2017/2018hasalsobeenoneofnewcollaborations.In2017wesignedamemorandumofunderstandingwiththeAssociationofBritish

PharmaceuticalIndustries(ABPI)-thefirstofitskindintheUK.Thisisanew,yetalreadyblossomingrelationshipwhichhasledtosometrulyinnovativeprojectsaroundtheeliminationofHepatitisC,pricingmodelsformentalhealthmedication,andimprovingthehealthofCOPDpatients.Someoftheseareoutlinedinourdeliveryprogrammesnapshotonpage16.

WealsohadthepleasureofaddressingseniorrepresentativesfromthepharmaceuticalindustryduringtheABPI’sAnnualConferencewhichhasalreadyyieldedsomeveryinterestingpotentialprojects.

InadditiontotheABPI,wehavealsostartedtheprocessofagreeingasimilarmemorandumofUnderstandingwiththeAssociationofBritishHealthcareIndustries(ABHI).Weexpectthesigningformalitiestobecompletedinthe2018/2019financialyear.

Asillustratedthroughoutthisreport,HealthInnovationManchesterisdeliveringahugeportfolioofprogrammesandprojectsthatwillhave,andarealreadyhavingaprofoundeffect,notjustonthehealthandwellbeingofour2.8mcitizens,butalsonationallythroughourworkwiththeAHSNNetwork(seepage7).

Finally,aswemoveinto2018/2019welookforwardtoforgingnewpartnershipsandcollaborationswithsystemstakeholdersandindustryinnovatorswhiledeliveringadiverserangeofexcitingprogrammesandembeddingthemechanisms,infrastructure,andcultureacrossthesystemtocreateanenvironmentwhereinnovationflourishes-enablingGreaterManchestertobecomeaninternationalleaderinacceleratinginnovationthattransformscitizens’healthandwellbeing.

21

Professor Ben BridgewaterChiefExecuticeOfficerHealthInnovationManchester

Rowena BurnsChairHealthInnovationManchester


ABOUTHEALTHINNOVATIONMANCHESTERAsanacademichealthscienceandinnovationsystem,HealthInnovationManchesterisattheforefrontoftransformingthehealthandwellbeingofGreaterManchester’s2.8millioncitizens.

ItwasformedinOctober2017bybringingtogethertheformerAcademicHealthScienceNetworkandAcademicHealthScienceCentreunderonesingleumbrella,whichalsorepresentsGreaterManchester’swiderresearchandinnovationsystem.

HereinGreaterManchester,wehavetheuniqueabilitytodeliverinnovationintofrontlinecareatpaceandscalethankstoour£6bndevolvedhealthandsocialcaresystem,unrivalleddigitalassetsandambitions,exceptionalacademicandresearchcapabilityandthrivingindustrypartnerships.

OurcollectiveambitionistomakeGreaterManchesteroneofthebestplacesintheworldtogrowup,getonandgrowold.

Despitehavingoneofthefastestgrowingeconomiesinthecountry,peopleheredieyoungerthanthoseinotherpartsofEngland.Cardiovascularandrespiratoryillnessesmeanpeoplebecomeillatayoungerageandlivewiththeirillnesslongerthaninotherpartsofthecountry.Ourgrowingnumberofolderpeopleoftenhavemanylong-termhealthissuestomanage.

Therefore,HealthInnovationManchesterhasapivotalroleinbringingforwardaconstantflowoftargetedinnovationsandputtingthemthroughaneffectivebutstreamlinedevaluationprocesssotheyareadoptedatpaceandscaleacrossour10localities.

Wedothisbyharnessingtheassetsofourworld-leadingresearchers,fosteringpartnershipswithindustryandsupportingourNHSandsocialcareproviderstoadoptinnovation,suchasthroughdigitaltechnology,changestopracticeoroptimisingmedication.

In2017/18ourthreebusinessobjectiveswere:

PositioningGreaterManchesterasaninternationallyrenownedlocationforlifescience,med-techanddigitalhealthcareresearchandinnovation.

Acceleratingthediscovery,developmentanddeploymentofinnovationthatimprovesourpopulationshealthandwellbeing

Contributingtonationalandinternationalhealthandlifesciencepolicy.

AlthoughHealthInnovationManchesterisanorganisationwhichdirectlyemployspeople,werepresentresearchandinnovationagenciesworkingacrossGreaterManchester.

ThesuccessofHealthInnovationManchesterisintertwinedwiththesuccessofourpartners,soweworkasonesystem.Thisincludescommissioners,providers,Universities,theBiomedicalResearchCentre,CollaborationforLeadershipinAppliedHealthResearchandCare(CLAHRC),ClinicalResearchNetwork,industry,nationalbodiesandinvestmentagencies.

AnoverviewofoursystempartnerscanbefoundontheHealthInnovationManchesterwebsite.

Asareflectionofthisdynamicsystem,theHealthInnovationManchesterBoardismadeupofleadersfromhealthandsocialcare,academia,researchandindustry.Thisensureswehavesystem-widebuyinofourstrategyandplans.YoucanreadmoreaboutwhotheBoardareonpage29.

TheBoardisunderpinnedbytwomaincommittees–theInnovationPrioritisationandMonitoringCommittee,aswellastheResearchandEducationCommittee.ThesecommitteesalsoincludenominatedrepresentativesfromacrossGreaterManchestertoensurewehavetheagreementandcommitmentfromall.Thissupportsquickerdecisionmakingandspeedsuptheinnovationpathway.

WereceivenationalfundingfromNHSEnglandaspartofourAcademicHealthScienceNetworklicenseandattractconsiderableinvestmentduetoourAcademicHealthScienceCentrestatus.WealsoreceivefundingfromourGreaterManchestersystempartners.Amoredetailedoverviewofourfinancescanbefoundonpage29.

InApril2018HealthInnovationManchesterbecamehostedbyManchesterUniversityNHSFoundationTrust,ensuringourworkisunderpinnedbytherobustgovernance,transparencyandstandardsexpectedofapublicbody.

Contributing to national and

international health and life

science policy.

43


2009 2013 2014 2015 2016 2017GreaterManchestersignedaground-breakinghealthandsocialcareagreementtogiveGreaterManchesterandlocalNHSservicesmuchmorecontroloftheregions£6billionhealthandsocialcarebudget.

MANCHESTERACADEMICHEALTHSCIENCECENTRE(AHSC)DESIGNATED

In2013NHSEnglandlicenced15AcademicHealthScienceNetworkstospreadinnovationatpaceandscale-puttinginnovationattheheartoftheNHStoimprovepatientoutcomesaswellascontributetoeconomicgrowth.

ThedevelopmentofAHSNswasrecommendedinSirDavidNicholsonsDecember2011reportInnovation,HealthandWealth

ManchesterbecameoneofsixaccreditedAHSC’sInEngland.TheroleofAHSCwasawardedinrecognitionofdepthandbreadthofclinicalandacademicexcellence.

15ACADEMICHEALTHSCIENCENETWORKSCREATED

GREATERMANCHESTERDEVOLUTIONAGREEMENTSIGNED

LANDMARKAGREEMENTCREATESHEALTHINNOVATIONMANCHESTER

KeyGreaterManchestersystempartnerssignlandmarkMemorandumofUnderstandingtocreateHealthInnovationManchester.

TheroleofHealthInnovationManchesterwastoleveragetheexceptionalassetsofthecityregiontoinpartnershipwithindustrytodriveresearchandprovenInnovationintohealthandsocialcareservicesatpace.

GREATERMANCHESTERDEVOLUTION

Asinglelocallyaccountablebody,theGreaterManchesterHealthandSocialCarePartnershiptookcontrolofpolicyandexpenditureacrossallNHS,populationhealthandsocialcareprovisionforit’s2.8mcitizens.

Thiscreatedtheopportunitytotakeasystem-wideviewofthemostpressinghealthneedsandenabledstreamlinedgovernancearrangementswithjointprovider-commissionerprioritysettinganddecisionmakingatsystemlevel.

HEALTHINNOVATIONMANCHESTERLAUNCHES

GreaterManchesterAcademicHealthScienceNetwork(GMAHSN)andAcademicHealthScienceCentre(MAHSC)cametogetherwithinthecity-regionsAcademicHealthScienceandInnovationSystem-HealthInnovationManchester.

OurJourney

65


NATIONALIMPACT:THEAHSNNETWORK

100%

WORKING IN PARTNERSHIPTheAcademicHealthScienceNetwork(AHSN)wasestablishedin2013asaresponsetothe2011Innovation,HealthandWealthreport.

ByconnectingtheNHSwithinnovators,notonlyhastheAHSNNetworkenabledthedevelopmentofsolutionstosomeofthemostchallengingproblemsinhealthcare,ithasalsostimulatedeconomicgrowth.

2017/18markedtheendoftheinitialAHSNlicenseperiod,howevertheOfficeofLifeSciencesiskeentobuildonthesuccessoftheAHSNnetworkandhascommitted£39mtoAHSNsoverthenextthreeyearstoestablishInnovationExchanges(acoredeliverableoftheAcceleratedAccessReview).

Movingforward,theAHSNNetworkwillbedrivenbyninekeyprioritieswhichwillformthebasisfor‘InnovationNationalNetworks’,(INNs),Theseinclude:

InnovationandEconomicGrowth.

InnovationExchange.

MedicinesOptimisation.

MedicalTechnology(MedTech).

DigitalandArtificialIntelligence.

Genomics,AdvancedDiagnosticsandPersonalisedMedicine.

PatientSafety.

QualityImprovement.

Research.

TheINNswillenableaconsistentapproachtodeliveringimpactacrossthe15AHSNs,operatingascommunitiesofexpertise;workingwithstakeholderstoidentifyandshareinnovationsandprioritisethosereadyfornationalspread.TheaimistostimulateconnectionswithinandbeyondAHSNsandinfluencenationalpolicy.

22Patientshave

benefittedromAHSNinput.

MILLION

5.5MILLIONPatientshave

benefitedfromour

PatientSafetyCollaborative

Work.

332INNOVATIONS

Havebeenintroducedandspreadthrough

significantAHSNinfluence.

500JOBSHavebeen

createdasaresultofAHSN

work.

15Peoplehavebenefitted

fromtheNHSInnovation

Accelerator.

MILLION

£42MILLION

Savingshavebeendelivered

totheNHS

MILLIONInvestmenttoimprovehealthandsupportourNHS,care,and

industrypartners

£330

NorthEastandNorthCumbria

Yorkshire&Humber

EastMidlands

Eastern

UCLPartners

HealthInnovationNetwork

Kent,Surrey,Sussex

ImperialCollegeHealthPartners

WessexSouthWest

WestofEngland

Oxford

WestMidlands

InnovationAgency

EastLancashireHospitalsNHSTrustsitswithHealthInnovationManchester

87


In 2017 / 2018 we have:

EstablishedtheGreaterManchesterResearchHubtoprovideanintegratedapproachforresearchdeliveryacrossthecity-region.Thisprovidesaone-stopforinterestedpartiestoaccessclinicaltrialsexpertiseandinfrastructure.

DevelopedanenhancedClinicalTrialsUnit(CTU)tosupportthenextgenerationofclinicaltrials(includingrealworldtrials)thataremoreresponsivetotheneedsoftheprivatesector.

CreatedaHealthInnovationManchester-NationalInstituteforHealthandCareExcellence(NICE)DataLab.Linkingdifferentdata-setstogetherandusingstate-of-the-artanalytics,theDataLabistestinghowbigdatacanprovideevidencerelatingtotheeffectivenessofnewandexistingtreatments,andproducenewhealthinsights.

Ledanddeliveredunderpinninginfrastructureinclinicalresearchexcellence,precisionmedicineandacademicinformatics.Thisapproachleverage’sthemaximumvalueofindustry(andother)partnershipstosupportcommercialinwardinvestmentandbusinessgrowthfrombasicresearchtomarketaccess.Wehavealreadyestablished40separatecompanyrelationshipsacrossmultipleareasincludingmajorpharmaceuticalcompanies.

Successfullysecuredcirca£90moffundingincludingNIHRBiomedicalResearchCentre(£28.5m),ClinicalResearchFacility(£12.5m),PatientSafetyTranslationalResearchCentre(£6.67m),gainedCRUKMajorCentreStatus(£39m)andECMCfunding(£2.75m)

LinkedthePatientSafetyCollaborative(PSC)tocuttingedgetranslationalresearchfromourNIHRPatientSafetyTranslationalResearchCentre.Thisenablesustoinfluencelocalpolicy,byensuringpolicymakershaveaccesstorobustscientificevidencearisingfromthelocaluniversitiesofGreaterManchestertoinformhealthandsocialcarestrategieswhichin2017/18includedGreaterManchesterDiabetesandMedicinesOptimisationStrategies.

IncreasedthenumberofNIHRSeniorInvestigators;GreaterManchesternowhasthehighestnumberofNIHRInvestigatorsintheNorthofEngland.

SecuredInnovateManchesterAdvancedTherapyCentreHub(MATCH)£9mawardfromInnovateUKtoestablishoneofthreeAdvancedTherapyTreatmentCentres.

Clinical research excellence

TheGreaterManchesterResearchHub,HealthInnovationManchestersupportsresearchgenerationanddeliverythroughconnectiontostateoftheartresearchinfrastructure,academicexpertise,aresearch-savvyworkforceandstreamlinedprocessesincludingcostingandcontracting.

OurclosecollaborationwithNorthWestEHealthalsoprovidesopportunitiestoempowerthelifescienceindustrytoruncosteffectiveclinicaltrialsfromfeasibilitystudiestofullclinicaltrialmanagementanddelivery.

Inaddition,HealthInnovationManchesterenjoysaproductiverelationshipwiththeGMLocalClinicalResearchNetwork(LCRN)whichisnumberonenationally(allowingforpopulationsize)forrecruitmenttolife-scienceindustryclinicaltrials.Consequently,theGMLCRNisapreferredproviderforanumberofpharmaceuticalcompaniesandContractResearchOrganisations(CROs).

Wearedevelopingapipelineofnewtreatmentsandpathwaysthatwilladdressthehealthneedsofourpopulationinyearstocome.

Throughrecognisedworldleadingexperimentalmedicinestudiesininflammatorydiseasesandcancer,ourpositionasoneofonlythreePatientSafetyTranslationalResearchCentreslinkedtotheNHSIPatientSafetyCollaboratives,andourongoingrelationshipwiththeNIHRCLAHRCinGreaterManchester;HealthInnovationManchesterisideallyplacedtodeliverinnovationthattrulyspansthediscovery-carecontinuum.£47m £39m

Funding awarded for NIHR Research Infrastructure

Awarded as a result of our CRUK Major

Centre Status

ALIGNING CLINICAL RESEARCH TO

SYSTEM NEED AND ACCELERATING THE

LEARNING INTO PRACTICE

100+Events delivered by

our NIHR PSTRC(Patient Safety Translational

Research Centre)

67,500Pharmacy colleagues

accessed our guide on risk management

109


UNLOCKING THE VALUE OF

INTEGRATED DATA SYSTEMS ACROSS

HEALTH AND SOCIAL CARE

In 2017 / 2018 we have:

Continuedtheroll-outofDataWellacrossthesystem.12

NHSorganisationsarenowconnectedtoDataWelland

886,563patientrecordshavebeenmapped.DataWellisakey

componentoftheGreaterManchesterDigitalInteroperability

Hub.

WorkedinpartnershipwithsystemstakeholderstoestablishtheGreaterManchesterHealthandSocialCareDigitalBoard.ThisboardisoverseeingambitiousplanstocreateanInteroperabilityHubandInnovationHub.TheInnovationHubwillallowhealthandcareproviderstoexchangedatamoreeasilyandsafelyaccrossall10localities.TheInnovationHubwillenhancehowweusedatatotransformservicesandenableground-breakingresearchandinnovationprojectsthatwillattractindustrypartnersandenableimplementationofchangeatpaceandscale.

SuccessfullysecuredacontractfromNHSEnglandtoworkincollaborationwithOxfordAHSNandArdenandGreaterEastMidlandsCommissioningSupportUnittodevelopaConnectedCareAssessmentTooltoassessplace-baseddigitalmaturity.ThetoolkitwassuccessfullypilotedacrosstwoSustainabilityTransformationPartnerships(STP’s)andawiderrolloutisplannedfor2018/2019.

UtilisationManagementUnitshortlistedfortheHSJValue

Awardinthecategoryofemergency,urgentandtraumacarein

recognitionofthecontributionandchangedrivenbythe100%

challengesthathavebeendeliveredover2017/2018.

Workedwith15hospitalsitestoimproveperformanceagainstthe4-hourAccidentandEmergencytargetforwaitingtimes;resultinginanaverage23.09%improvementinA&Eagainstthetargetaswellasa15%improvementinpatientsatisfaction.

Informatics and analytics

InGreaterManchesterweenjoyaninternationallyleadingpositionintheintegrationofdataandtheuseofreal-worldevidencetodrivepolicy,researchanddeliveryofcare.

HealthInnovationManchesterisbuildingonthesestrengths,joininguphealthandsocialcareinformationsothatwecancreate:

Aregion-widelearninghealthsystemthatoptimisesthedeliveryofcarebasedoncontinuoussystemevidence.Thisincludesanearreal-timeviewofhealthcareutilisationtoensureweoptimisecarepathwaysandvalueformoney(UtilisationManagement).

Data-richobservationalstudies,precisionmedicinecapabilityanddiscoveryscience,trialsandeconomicevaluationsofmedicinesanddevicesaswellasotherinterventionsthatcanbeundertakenacrossthepopulationquicklyatlowcost.

Ourreputationhasalsoattractedinterestanddemandnationallyandinternationally.In2017/2018ourUtilisationManagementUnitcompletedcommissionsfromthewiderhealthcaresystemsparticularlyinrelationtourgentandemergencycare-generatingover£1minrevenuetoinvestbackintothesystem.

886,563 1in 3Thousand records are now mapped within

DataWell

NHS organisations in GM are now connected to

Datawell

86%Of GM leaders that

recieve UM analytical reports use them

daily

£1m+Revenue generated

by the Utilsation Management Unit

this year

1211


TRANSFORMING THE HEALTH AND

WELLBEING OF OUR 2.8M CITIZENS

In 2017 / 2018 we have:

WorkedcollaborativelywiththeAtrialFibrillation(AF)AHSNnetworktodelivernationalandlocalimprovementsaroundAFmanagementanddetection.Thishasalreadypreventedanestimated13strokesinGreaterManchesterandresultedin468patientsbeingofferedtreatmentwithspecialistpharmacists,andwherenecessaryassessmentinprimarycare.

DeliveryofthefirstAtrialFibrillationCCGpharmacy-ledanticoagulationclinicwhichidentified6,059patientsacrossthecityofManchesterwitha‘readcode’ofatrialfibrillation.Ofthese1,603patientswere‘knownnottreated’whichequatesto52expectedstrokes.Wearenowfundingawork-streamin2018/19totacklethis.

DeploymentofERAS+,apre-andpostoperativesurgeryprogrammetooptimisepatientrecovery.Implementationatonetrusthasreducedpost-surgerypulmonarycomplicationsby50%resultingina3dayreductioninlengthofstayandannualsavingsofover£0.5m.A£500kgrantawardhasbeensecuredfromtheHealthFoundationtotakethisworkforwardincludingtheroll-outacrosssixtrustsinGreaterManchester.

DeliveredacontroltrialofaTroponin-onlyManchesterAcuteCoronarySyndromes(T-MACS)decisionaidtoolthatwasdevelopedinGreaterManchester.ThishasalreadyresultedinabenefittopatientssuspectedofAcuteCoronarySyndromeandfinancialsavings.ThisisnowbeingdeployedacrossGreaterManchesterandthewiderUK.

DeliveredthefirstRainbowClinic-aspecialistserviceforwomenandtheirfamiliesinasubsequentpregnancyfollowingastillbirthorperinataldeath.Thishasalreadybenefited140families,prevented9like-for-likestillbirths(Contributed2.19%oftheavoidedstillbirthsnationwideduringoperation)andhasgeneratedan8foldreturnoninvestment.ThisisnowbeingdeployedacrossGreaterManchester.

IncorporatedPINCER:(pharmacist-ledinformationtechnologyinterventionformedicationerrors),anauditsoftwarepackagewhichhelpsGPpracticesreviewpatientcaseloadsandhighlightpatientswhomaybeatriskofprescribingerrorsintoGMPrimaryCareMedicalStandards.Thisisresultinginareductioninmedicationsafetyincidentsandreducingunwarrantedvariation-improvinghealthoutcomesforourpatientpopulation.

Health and implementation

HealthInnovationManchesterisdeliveringalargeanddiverserangeofprojectsinpartnershipwithindustry,healthandsocialcarecommissionersandproviders,andthenationalAHSNNetworkto:

Improvehealthoutcomesacrossthe

HealthInnovationManchesterfootprint

throughthesystematicreductionofthe

numberofdeaths.

Spreadatpaceselectedinnovationsthat

willimprovethehealthofthepopulations

weserveandcreateasustainableAHSNfor

GreaterManchester.

Createaclimateandsupporting

infrastructureforentrepreneursand

innovatorstodevelopideaswithinthe

NHS,therebycreatinghealthandwealth.

Supportourmembersandstakeholdersin

theirrelatedprioritiesandambition.

Over2017/2018wehavebeenprogressing

projectsacrossamultitudeofareas,which

includecardiovasculardisease(CVD),

mentalhealth,emergencymedicine,cancer,

respiratoryandnationalAHSNprogrammes

-manyofwhicharehighlightedin‘current

deliveryprogrammes’onpages16to22

Themanagementteamalsoworksvery

closelywiththePatientSafetyCollaborative

Team,withbothareassynergisingprojects

wherethereismerit.

9 13 £500k £8kStillbirths have been

prevented by the Rainbow Clinic

Estimated number of Strokes prevented by

the AF programme

Savings at one hospital trust

implementing ERAS+

Potential medicine reimbursements at 2

hospital trusts

1413


PROJECTS

OVERVIEW

A brief overview of some of the 50+ projects being delivered by Health Innovation

Manchester over 2017/2018 that will continue into 2018/2019

Accelerating the discovery,

development and deployment

of innovation that improves

our population’s health and

and wellbeing.

1615


CURRENTDELIVERYPROGRAMMES

IMPROVING CARE FOR PEOPLE WITH COPD

HealthInnovationManchesterisworkingwithhealthandindustrypartnerstodevelopandimplementanambitiousplantoradicallyimprovethecareandtreatmentofpeoplewithCOPDacrossthe10localitiesofGreaterManchester.

COPDisthefifthbiggestkillerintheUK.PatientswithCOPDsufferwithseverebreathingdifficulties,oftenresultinginhospitalisation.Therearearound67,000patientsdiagnosedwithCOPDlivinginGreaterManchesterandtherearelikelytobehundredsmoreunknowinglystrugglingwiththedisease.

ThecostofmanagingCOPD-relatedhospitaladmissionsandmedicationsforGreaterManchesterisaround£73millioneachyear,withfurtherindirectcostsestimatedtobeasmuchas£1.8

billion.Infact,thecity-regionhasthesecondhighestadmissionratesforCOPDinEngland,aswellaspooroutcomesandunwantedvariationbetweenGPPracticesandlocalities.

Theprogrammebuildsontheground-breakingSalfordLungStudy,whichexaminedthesafetyandefficacyofnewmedicationstotreatrespiratoryillness.

Thiswastheworld’sfirstdigitallyenhancedrandomisedreal-worldtrialtoincludeabroadandinclusivepopulationofpatientsinaneverydayclinicalpracticesetting-madepossiblebythesingleelectronicmedicalrecord.

TheaimoftheCOPDprogrammeistoimprovethehealthofCOPDpatientsthroughclinicallyappropriateandcost-

effectivetreatmentusinginhalers.Thiswillbeachievedthrough:

Reviewingpatients’existingtripletherapyprescribingtoidentifythosewhocansafely‘stepdown’fromthecorticosteroidelementoftheirmedication,

ReviewingpatientsreceivingmedicationwhichisnotinlinewiththelatestGreaterManchesterMedicinesManagementGroup(GMMMG)guidelinestoenablepatientstoswitchtorecommendedalternativeswhereclinicallysafetodoso.

ELIMINATION OF HEPATITIS C

GreaterManchesterhastheambitiousaimtobecomethefirstUKcityregiontoeliminateHepatitisCby2021.

Thevirus,whichaffectstheliver,cansometimescauseseriousandpotentiallylife-threateningdamageifleftuntreated.

Thereareestimatedtobearound17,450peopleinGreaterManchesterlivingwiththeinfection,includingaround7,000whoareundiagnosed.Ofthosediagnosed,only28%areengagedwithspecialistservices.

TheHealthInnovationManchester

projectaimstoeliminateHepatitisCbyusinganetworkedandphasedapproach.

Communitypharmacieswilldeliverpointofcaretestinganddrybloodspottestingtomaximisethenumberofpeopletestedandidentifyhighriskpatientsaswellasprovidingtreatmentinamoreconvenientlocationfortheindividual.

Pharmacieswillbetargetedintermsofmethadonedispensingandopiatereplacementtherapyaswellasthoseoperatingasafeneedleexchange.

Followinganinitialpilot,theprojectwilllooktotestandtreatthewiderpopulationgroupsathighriskofinfectionandarapidtestingandtreatmentregimewillalsobeimplementedforthoseinorenteringprison.

Theprojectaimstobringspecialistservicestothepatientatthepointofneedanddevelopanew,morecost-effectivetestingandtreatmentinfrastructure.Itwouldalsoresultinareductioninassociatedhealthcarecostsandabetterqualityoflifeforpatients.

ERAS+ ENHANCED RECOVERY AFTER SURGERY

PatientsundergoingsurgeryatsixGreaterManchesterhospitalswillbepreparedfortheexperienceinthebestpossiblewayusingtheEnhancedRecoveryAfterSurgery(ERAS+)programme.

Thesurgicalpathwaybuildsonthesuccessofthein-hospitalprogrammebutexpandsittoincludesixweeksofpre-surgerypatientpreparationandpost-hospitalrecoverysixweeksafter,withpatientsandtheirfamilysupportedthroughaSurgerySchool.

Therearearound250,000high-riskelectivemajorsurgeriesayearinEnglandandWalesandthereisapost-operative

pulmonarycomplicationrisk(PPC)ofupto30%.Complications,suchrespiratoryfailureorpneumonia,canincreasethelengthofstayinhospitalandreducelifeexpectancyaftersurgery.

TheERAS+programmeplacesthepatientatthecentreoftheirownrecoveryandsupportsthemtobedynamicintheirowncare.Itencouragesincreasedactivity,betternutrition,oralhealthcareandthepracticeofchestexercisestohelpreducechestproblems.

Itaimstoreducecomplicationspost-surgery,withevidencesuggestingareductioninpulmonarycomplications

by50%,reducethelengthofstayinhospitalbyaroundthreedaysandimprovequalityoflifeforpatientsforsixto12monthsaftermajorsurgery.

TrustsparticipatinginERAS+areManchesterUniversityNHSFoundationTrust,StockportNHSFoundationTrust,BoltonNHSFoundationTrust,ThePennineAcuteHospitalsNHSTrust,SalfordRoyalNHSFoundationTrustandTheChristieNHSFoundationTrust.

HEALTHY HEARTS: SYSTEMATIC IDENTIFICATION OF HIGH-RISK CVD PATIENTS

HealthyHeartsisaninnovativeprogrammeaimingtoreducedeathsfromCardiovascularDisease(CVD)throughbetteridentificationofthoseatriskofheartattackorstrokeinGreaterManchester.

TheprojectwillworkcloselywithClinicalCommissioningGroupstofindthoseathighestriskofCVD,includingthosewithhighbloodpressureandhighcholesterolinasystematicandtargetedapproach.Theprogrammewillalsolinkwithtargetedhealthchecksandlifestyleinterventions.DatashowsthatifeachCCGintheareareachedthelevelofthe

fivebestsimilarCCGs,therewouldbe356fewerdeathsforunder75-year-oldseachyear.

Itisestimatedthatidealcontrolofdiagnosedhypertensives–thosepatientswithhighbloodpressure–couldsave470heartattacksand700strokesoverthreeyearsinGreaterManchester,afinancialsavingofover£13.2million.

TheprojectaimstoreducedeathsfromCVDbyatleast600by2021andidentifythoseathighestriskofCVDtoenabletreatment,lifestyleinterventionsand

self-managementopportunities.HealthInnovationManchesterhasalsoprovidedpracticesinGreaterManchesterwithaccesstotheAliveCorKardiahand-heldAtrialFibrillation(AF)detectiondevicetoimprovecareforpeoplewithAFandreduceAF-relatedstrokes.

ThemobileECGdeviceshelpwiththedetectionofpeoplewithAFinclinicaland/orcommunitysettings.

1817



GREATER MANCHESTER & EASTERN CHESHIRE PATIENT SAFETY COLLABORATIVE

Safetyandensuringpatientsarenotharmedwithinahealthandsocialcaresettingiseveryone’sresponsibilityandGreaterManchesterisinauniquepositiontobeabletosupportandcreateasmoothpathwaytoimprovement.

ThroughthePatientSafetyCollaborative,ajointinitiativefundedandcoordinatedbyNHSImprovementanddeliveredbyHealthinnovationManchester,wecanworkdirectlywithlocalteams,supportingthemtomakesuretheyhavetherightskillsandresourcestoimplementimprovements.

Wecanalsosharegoodpracticeacrossthehealthsystem,focusonpeople-centredcareandbuildrelationshipswith

NHSstaff,businessandacademiatostimulateinnovationandimprovement.ThePSCwillfocusonthreenationalareasofwork:

DeterioratingPatients:Toreduceharmandenhancetheoutcomesandexperienceofpatientswhoaredeteriorating.

CultureandLeadership:Tohelpcreatetheconditionsthatwillenablehealthcareorganisationstonurtureanddevelopacultureofsafety.

MaternityandNeonatal:Toimprovematernityandneonatalcare,specificallyreducingtherateofstillbirth,neonataldeathandbraininjuriesoccurringduringorsoonafterbirthby20%by2020.

ThePSChasbeensetuptosupport,connectandprovideinitiativesandactivitiestodriveimprovementandensurepatientsafetyisembeddedthroughouttheGreaterManchesterhealthandsocialcarecommunity.

RAINBOW CLINIC: SPECIALIST ANTENATAL SERVICE

Becomingpregnantagainafterastillbirthisanincrediblydauntingprospectforwomenandfamilies,oftencharacterisedbythefearofrepeatingtheexperience.

Womenwhohavehadastillbirthareatincreasedriskofcomplicationsinsubsequentpregnancies,includingstillbirth,pre-eclampsia,placentalabruptionandlowbirthweight.

Itisalsoassociatedwithincreasedpsychological,emotionalandsocialchallenges.

TheRainbowClinic,atSaintMary’sHospital,isaspecialistservicefor

womenandtheirfamiliesduringasubsequentpregnancyfollowingastillbirthorperinataldeath.

Itcaresforfamiliesfromthetimeofthepostnatalappointmentonwardsandintoasubsequentpregnancy.

Itengageswithwomenearly,ensuringtheyareontherighttreatment,makinganynecessaryreferralsandprovidingmoredetailedultrasoundscanning.

Theadditionaltestsandcontinuityofcare,providedbyasmallteamofspecialistdoctorsandmidwives,resultinimprovedoutcomesforthebabyaswell

asimprovedpsychologicalwell-beingforparentandbetteruseofNHSresources.

HealthInnovationManchesterwillsupportthescale-upacrossGreaterManchestermaternityunits,aimingtoreducetheratesofmaternaldeaths,stillbirths,neonataldeathsandbraininjuriesthatoccurduringorsoonafterbirthby20%by2020andthenby50%by2030.

ThecharityTommy’sisalsogivingadditionalfinancialsupportasvalidationoftheclinicalprogresstoensurescaleandspreadoftheproject.

REDUCTION OF FRAILTY-RELATED FALLS AND FRACTURES

Forolderpeoplelivingwithfrailty,afallorfracturecanresultinarapiddeteriorationinhealthandsignificantlossofindependence.

Thereareapproximately65,000hipfracturestakingplaceintheUKeachyear,costingthehealthandsocialcaresystemaround£2billion.Itisimperativethatsystemsareinplacetohelpidentifypeoplewhoareatriskoffallsandfracturestoensurethereareappropriatetreatmentandservicesthatmeettheirneeds.

TheHealthInnovationManchesterprojectaimstoreducefallsandfracturesrelatedtofrailtyacrossGreaterManchesterthroughearlyintervention,treatmentandmanagementofat-riskpatients.

Theprojectwillsupportprimarycarebyfindingat-riskpatientssothatthey

canbetreatedwithappropriatebone-sparingtherapies,includingmedicationtostrengthenbones,andsupportedwithservicesinthecommunitytohelpmanagetheircondition.

Throughearlyandincreasedidentificationofosteoporosisandotherhigh-riskfactors,theestablisheduseoffractureriskassessmenttoolsinprimarycareaswellaspatientbehaviouralandlifestylechangesthrougheducationprogrammes,itishopetherewillbeareductioninfracturesandassociatedcosts.

PhaseoneisbeingundertakeninTamesideandGlossopLocalitywiththeDukinfield,StalybridgeandMossleyFrailtyMultidisciplinaryTeam(MDT)pilotlaunchedon31January2018.

Ithasbeensetupasavehicletosupporttheidentification,reviewand

managementofseverelyfrailpatientsusingtheelectronicFrailtyIndexandfractureandfallsriskassessmentITtools.

OnceapatientisidentifiedasbeingseverelyfrailtheMDTmembersdiscussandagreeonasetofappropriateoutcomesandactionstosuittheneedsofthepatientwhichcanincludeseveralclinicalandnon-clinicalinterventions.

Thismayincludereferralstocommunitygroups,physiotherapy,CommunityResponseService,Extensivistservice,socialprescribing,prescriptionofbonestrengtheningmedication,etc.

EightweeksaftertheMDTmeetingafollowupiscarriedouttoensurethatallagreedoutcomesandactionshavebeenachieved.

MENTAL HEALTH PRICING REVIEW MODEL

HealthInnovationManchesteraimstodemonstrateinnovationinthefieldofmentalhealththroughthetestingofanoutcomesbasedpricingmodelforschizophreniatreatments.

Second-generationantipsychotics(SGAs)representanadvanceinthelong-termmanagementofschizophrenia,particularlyregardingextrapyramidalmotorsafetyandsubjectivetolerability.

However,theevidencethatthemedicationsareeffectiveformaintenanceandstabilityislimited.

Asarelapseinschizophreniacancostbetween£12,000and£25,000,industry

partnerJanssenhavedevelopedanoutcomespaymentschemeandrebatetodemonstratetheirbeliefthattheirmedicinescanplayaroleinpreventingrelapseandthekeycostthatgoeswithit.

WorkinginpartnershipwithHealthInnovationManchester,JanssenofferedMentalHealthTrustsinGreaterManchesteraccesstotherebateschemewhichreimbursestheproviderifthetreatmentdoesn’tworkasplanned.

Theschemeproposesarefundforthecostoftheinjectionshouldtheperson,prescribedtheinjection,failtoachievetherequiredoutcome.

The scheme has provided real-world data as to whether the second-generation antipsychotic injections prevent relapse and admission as well as potential financial savings of £10,000 against medication costs for 2017, with the scheme in place for two trusts until June 2021.

The anticipation is that the tracking of the patient journey and understanding discontinuation and relapse will lead to better care with improved outcomes.

2019



DEMENTIA

GreaterManchesterisaimingtobe“thebestplacetolivewithdementiaintheworld”andHealthInnovationManchesteriscommittedtosupportingworktowardsthisvision.

Itisestimatedthattherearecurrentlyover30,000peoplelivingwithdementiainGreaterManchesterwiththecityregionspending£270millionayeartreatingandcaringforpeoplewithdementia.

Withanageingpopulationandrisingnumbersofpeoplebeingdiagnosedwithdementia,itisoneofthegreatesthealthchallengesfacingthecountryandGreaterManchester.

TheDementiaUnitedOperationalGroupareworkingwithpartnersacrossGreaterManchestertoimprovetheexperiencesofpeoplewithdementiaandtheircarers,andreducepressureonthehealthandsocialcaresystem.

HealthInnovationManchesterwillsupportDementiaUnitedthroughtheidentificationandimplementationofsuitablenewinnovationstosupporttheoverallobjectives.

Workinginpartnershipwithindustry,HealthInnovationManchesterwilldeliveranearlydetectionanddiagnosticsframeworkfordementia–buildingontheprinciplesofpre-empt

andpreventtodetectandinterveneeveryearlyinthepathwayofcognitivedecline.

Thevisionistoimproveoutcomesbyensuringoptimalaccessanduptakeofinnovativetechnologiesandtreatmentsforeligiblepeople,aswellasensuringthehealthandcaresystemisgearedtoprovidethebestsupportforpeoplelivingwithdementia.

T-MACS: TROPONIN ONLY MANCHESTER ACUTE CORONARY SYNDROMES DECISION AID

Patientspresentingwithchestpainattheemergencydepartmentarethegroupmostcommonlyrequiringhospitaladmission.Troponinsareafamilyofproteinsfoundinheartmusclesthatproduceamusclecontractionwithserialtroponintestingremainingthestandardofcaretoruleoutheartproblems.

TroponinonlyManchesterAcuteCoronarySyndromes(T-MACS)isadecision-aid,acomputerisedclinicalpredictionmodelwhichcalculateseachindividualpatient’sprobabilityofacutecoronarysyndromesfollowingasinglebloodtestatthetimeofarrival.Thisprobabilityisusedtoassigneachpatient

totherelevantriskgroupandsuggestacourseofactionforthecliniciantofollow.

SinceimplementationatManchesterRoyalInfirmary,over3,500patientshavebeentreatedusingT-MACS,withthealgorithmprovingsuperiortoNICEguidelines.

Morethantwo-thirdofpatientscanbetreatedinanambulatorycaresetting,suchasoutpatientclinicsoremergencydepartments,withthevastmajoritydischargedonthesameday,comparedtoatwo-dayaveragestaywithroutinecare.

T-MACSwonManchesterFoundationTrust’sTransformationPrizein2016andHealthInnovationManchesteraimtoimplementitacrossGreaterManchestertoincreasethequalityandefficiencyofhealthcareprovidedtopatient.

Theprojectcouldresultinimprovedqualityoflifeforpatients,duetoquickerandmoreeffectivediagnosisandtreatment,moreappropriatetriagingofpatientsandisprojectedtosave£100millionperyearifrolledoutacrosstheNHS.

QUALITY IMPROVEMENT - LIFE QI AND THE Q COMMUNITY

HealthInnovationManchestersupportsasystem-wideapproachtodrivingqualityandimprovementandoffersafreetooltohealthandsocialcareorganisationsacrossGreaterManchester.

LifeQIisaweb-basedplatformdesignedtoassistfrontlinestaffrunningQualityandSafetyimprovementprojectsandconnectwithacommunityacrossthecountrytosharebestpractice.

Thetool,developedaspartofthePatientSafetyCollaborativeinpartnershipwithSeeData,supportsfrontlineNHSandsocialcareteamstoplan,monitorandreportprogressoftheirimprovementprojects.

TheflexibleLifeQIapplicationcontainstoolstohelpimprovementworkandmakeiteasytoseeprogress.Itallows

teamstocreatedriverdiagrams,conduct“Plan,Do,Study,Act”(PSDA)cyclesandvisualiseresultsthroughcharts,aswellascreatingabankofQIprojectswhichcanbeshared.

UserscanalsoconnecttoaQIcommunityofpracticeacrossthecountry,encouragingcollaborationwithteamsworkingonsimilarchallenges,avoidingduplicationandsharinglearningandsuccesswhilebuildinganetworkofpeoplecommittedtoimprovingcare.

Morethan140peopleandorganisationsworkingonserviceimprovementprojectshavealreadysigneduptotheLifeQItoolthroughHealthInnovationManchester.

HealthInnovationManchesterhasalsopartneredwithAdvancingQuality

Alliance(AQuA)andTheHealthFoundation’sQCommunityfortheQBookClubevents.

TheQcommunityisaninitiativeconnectingpeoplewhohavehealthandcareimprovementexpertiseacrosstheUKwithopportunitiestoshareideas,enhanceskillsandcollaborate.

TheQCommunityBookClubwillfeaturefivesessionswhichwillexaminekeyqualityimprovementliterature,hearfromlocalandnationalimprovementleadersandexploreonlinetoolstohelpQcommunitymemberssharediscussionandapplylearning.

GREATER MANCHESTER BIOLOGICS OPTIMISATION - VIRTUAL BIOLOGICS CLINIC

HealthInnovationManchesterissupportingasystem-wideapproachtoreducingunnecessarywastageofhigh-costbiologicdrugsacrossGreaterManchester.

Currentlythereisasubstantialspendingonapprovedbiologics,aclassofmedicationthatisnotsynthesizedchemicallybutinsteadharvesteddirectlyfrombiologysuchasenzymesorantibodies,withanestimated£45-50millionspentacrossGreaterManchester.

Alongsidethishighspend,thereareloosegovernancearrangementsfortheiruse,withpoormechanismsinplaceto

adequatelytrackandrecordusage.AVirtualBiologicsClinic(VBC)wascreatedatManchesterRoyalInfirmaryinordertoensurethattheprescriptionofbiologictherapieswasbasedprimarilyontheneedsofpatientsandnotoncostandtoincreasethespeedatwhichpatientscouldgainaccesstothetreatmentandprovidemoreopportunitiesforpatientstoparticipateinclinicalresearch.

TheVBCeffectivelyimplementedapan-ManchesterbiologicspathwayinRheumatologyatMRIwiththeinnovationschangingthedepartment’sprescribingpatternsandincreasing

researchrecruitment.Italsoincreaseddepartmentalefficienciesandgeneratedcostsavingsthroughhigheruptakeofcheaperbiologicstherapies.

DevelopingaVBCandbiologicoptimisationinitiativesinallGreaterManchesterTrustswouldcreateaneffectivewayofdeliveringbiologicsforpatientsinthemostcost-effectiveway.

2221


In 2017 / 2018 we have:

BroughttogetherManchesterAcademicHealthScienceCentre(MAHSC)andGreaterManchesterAcademicHealthScienceNetwork(GMAHSN)intoasingleorganisation-HealthInnovationManchester.Thisbringstogethertheentirediscovery-carecontinuumfromresearchtoimplementationundertheumbrellaofasingleentity;workinginpartnershipwithindustrytodriveresearchandinnovationthatisalignedtohealthandsocialcareneeds.

DevelopedasingleinnovationpathwayfortheentireGreater

Manchesterhealthandcaresystem-simplifyingthelandscape

forresearchersandindustryinnovators.Thissystematic

approachensuresthatthesystemhasabalancedpipelineof

innovationalignedtothecityregion’sneeds,andamorerapid

andassuredjourneyforinnovationsfromdiscoverythroughto

deployment.

BeganestablishingtheInnovationPrioritisationandMonitoring

Committee(IPMC);asub-CommitteeoftheHealthInnovation

ManchesterBoardmadeupofstakeholdersrepresentingthe

wholesystemwhoseremitistoprioritiseandoverseethe

innovationandimprovementworkprogrammeacrossthe

GreaterManchesterhealthandsocialcaresystem.Thisensures

system-wideengagementpriortosystem-widecommissioning.

SignedtheUK’sfirstMemorandumofUnderstandingwiththe

AssociationofBritishPharmaceuticalsIndustry(ABPI).This

articulateshowtheGreaterManchestersystemwillwork

collaborativelywithpharmaceuticalcompanies.Despite

itsinfancythishasalreadyledtosomeveryinnovative

partnershipsacrossareassuchasCOPD,HepatitisC,virtual

biologicsandmentalhealth.

LaidthegroundworkforaMemorandumofUnderstanding

withtheAssociationofBritishHealthcareIndustries(ABHI).

Thiswillbesingedin2018andenableustodriveforward

partnershipworkingwithmedicaltechnologycompanies.

Industry partnerships

GreaterManchesteristheonlycity-regioninEnglandwithcontrolofitscombinedhealthandsocialcarebudgets.

AsingleaccountablebodywithdelegatedresponsibilitiesnowcontrolspolicyandexpenditureacrossallNHS,populationhealthandsocialcareprovisionforits2.8mcitizens.

Thishascreatedauniqueandexcitingopportunitytotakeasystem-wideviewoftheregion’smostpressinghealthneeds;joininguptheworkofallhealthandsocialcarecommissionersandproviderstomeettheseneedsinthemostefficientandcost-effectiveway.

Empoweredbythishealthandsocialcaredevolution,HealthInnovationManchesterisprovidingamuchsimplifiedlandscapeforresearchersandindustryinnovators.

Thisincludesasinglegatewayintothesystemwithasingleinnovationpathwaythatcapitalisesonthecityregion’sstreamlinedandaccelerateddecision-makingstructures;providingindustryinnovatorswithanenhancedlevelofassuranceandspeedierdecision-makingintermsofadoptionfollowingproofofconcept.

200 66%AliveCor devices

deployed accross the GM system

of GM Maternity sites have adopted the

Episcissors-60

40 Months from Relvar

Ellipta phase III clinical trial to

adoption in GM

1st UK Memorandum of Understanding with the Pharmaceutical

Industry

CREATING A SIMPLIFIED

LANDSCAPE FOR INDUSTRY WITH MORE ASSURED

ROUTES TO ADOPTION AND

SPREAD

2423


SUPPORTING INDUSTRY TO

TAKE INNOVATIVE PRODUCTS AND

SERVICES INTO THE LIFE SCIENCES

MARKET

In 2017 / 2018 we have:

Provided£26,000fundingacross2organisationsforearlystage

developmentofinnovativesolutionsviaour’Ignite’funding

call.

Distributedupwardsof£98,000fundingtosupportmarket

readyproductsandservicesthroughour‘Momentum’funding

call,resultinginadditionalleveragedfundingof£500,000

(venturecapital).

Providedassistanceandsupporttoover108industry

innovatorsviaourawardwinningInnovationNexus;providing

information,accessandsupporttodevelop,test,anddeliver

innovativeproductsandservicesincollaborationwiththe

healthandsocialcarecommissionersandproviders.

WorkedcollaborativelywithNICEtodevelopamedical

technologyearlytechnicalassessment(META)gapanalysis

tooltohelpproductdevelopersunderstandwhatevidence

isrequiredtomakeaconvincingcasetopayersand

commissionersabouttheirtechnology.

DeliveredtheStepIntoHealthprogrammeto3cohortsof

30companiestohelpthemimprovetheirproductpitchand

increasetheirchancesofprocurementandsuccessinthelife

sciencesmarket.

Deliveredaregionaldigitalhealthacceleratortargeting

innovativedigitalhealthbusinesses;providingsuccessful

applicantswithopportunitiestoengageclinicalandhealthcare

expertiseandNHSprocurementsupport,aswellashelping

themunderstandthehealthsystemanditsneeds,develop

theirbusinessmodels,andrefinetheirpropositions.

ActedastheleadpartnerontwoSBRIcallsforreducing

pressureonurgentandemergencycareandimprovedcancer

diagnosis;definingtheclinicalneedandprovidingbusiness

assessors.

Engagedwithupwardsof111companiesthroughtheEuropean

RegionalDevelopmentFund(ERDF)Programme

Industry and wealth

HealthInnovationManchesterisactivelytargetinginnovationsthatspanthehealthandsocialcarespectrum;boththosethatrequiretrialling,orhavealreadybeentrialledandthosewhichrequiresystem-wideadoption.

InGreaterManchesterwehaveanintegratedinnovationpathwaythatmaximizesthebenefitsofourlocalecosystemtoentrepreneursandallowsthemtoaccesstheadvice,fundingandpartnershipsthatwillbeessentialfortheirsuccess.

CentraltothedeliveryoftheInnovationPathwayhasbeenthedeliveryandon-goingdevelopmentofHealthInnovationManchester’sInnovationNexuswebportalandadvisoryservice,thewinneroftheNorthofEnglandBusinessServiceawardsin2016.

TheInnovationNexusenablescompaniestolodgeenquirieswithanintelligentinterfaceandreceiveeithersignpostingand/orguidance,orwhenappropriate,follow-onsupportservicestoassistwithprogressionthroughthedevelopmentpathway,fromearlystageclinicalengagement,toassistancewithadoptionandprocurementintotheNHS.

Overthepastfinancialyear,HealthInnovationManchester haS also been delivering a matchfundedEuropeanRegionalDevelopmentFund(ERDF)programmeineasternCheshire.

This has involved working with SME’s withinnovative products and services to providesupporttoworkwiththeNHSandgrowtheirbusiness.

£4.29m 402 383 £1m+Leveraged funds

have been secured in 2017/2018

Enquiries recieved via the Innovation

Nexus since its launch

Companies assisted via the Innovation

Nexus since its launch

Innovation grants awarded since the Innovation Nexus

launch

2625


EMBEDDING THE SKILLS

AND CREATING THE CULTURE

WITHIN THE GM WORKFORCE TO

INNOVATE

In 2017 / 2018 we have:

ExpandedourMResinCancerExperimentalMedicineto

includeallthemesofourBiomedicalResearchCentreand

therebybuildexperimentalmedicinecapacitymorebroadly.

Furthermore,wehavecontinuedtorecruitsuccessfullytoour

comprehensivesuiteofprogrammesinHealthDataScience,

BioinformaticsandGenomicsthatrangefromaccreditedshort

coursestoMSc/PhDlevels.Accreditedcomponentsofthe

aboveprogrammescoupledwithspecialtyspecificmodules

canbecombinedintoflexiblepostgraduateprogrammesfor

clinicaltrainees.

DeliveredanewcollaborationbetweenwithTheRoyalCollegeofPhysiciansofEdinburgh(theRCPE)throughtheopeningofanofficeinManchester(RCPEManchester)inJune2017.TheRCPEiscommittedtopromotingthehighestclinicalstandardsandtheimplementationofrobust,evidence-basedmedicalpractice.TheRCPEhashostedanewseriesof‘hottopic’eventsandinternationalconsensusconferences,developingblendedlearningopportunitiesandco-badgedpostgraduatequalificationsandtherebyincreasinglocaltrainingandCPDopportunities.TheRCPE’sexistingnetworkofnationalandinternationalcentreswillbeusedtolive-streameducationalandtrainingeventsaroundtheworld.

DeliveredaOneManchesterTranslationalResearchTrainingDaywhichwasattendedbyover100PrincipalInvestigators,ResearchNursesandResearchProgrammeManagers(RPMs)fromacrossGreaterManchester.

DesignedanInnovativeDevelopmentalFrameworkthathasbeenpilotedbyourResearchProgrammeManagerNetwork(over130members)whichspecifiescompetencystandardsforeachleveloftheirappointment.

DeliveredaClinicalBioinformaticsMassiveOnlineOpenCourse(MOOC)designedtoprovideskillstohealthcareprofessionalstoenabletheanalysisandinterpretationofgenomicdata.Thishasattractedover13,000participantstodatefromacrosstheworld.

Education and training

GreaterManchesterisacityunitedthroughpartnershipsestablishedforthebenefitofourpopulationandourlocaleconomy.

Asaregionofhighdiseaseburdenandhealthinequality,itisessentialthatourcitizensreceivethehighestqualityhealthandsocialcareprovision,deliveredbyahighlytrainedworkforceofhealthandsocialcareprofessionals.

ThroughtheopportunitiesprovidedbyGM’shealthandsocialcaredevolutionandthecreationofHealthInnovationManchester,wenowhaveameansofconnectinghealth,socialcare,highereducationinsight,andindustryorganisationswiththehealthandsocialcareprioritiesofourpopulation.

ThroughpartnershipworkingwithourlocalHEIsweplantodevelopGreaterManchester’sfirst‘Ed-City’.

Thisinitiativewillprovideaneducationandtrainingecosystemthatbringstogetherexpertiseineducation,bestpracticeinitiativesfromtheGreaterManchesterHealthandSocialCarePartnership,andlearninginfrastructuretoenhancetheeducationandtrainingneedsofournursingandalliedhealthprofessionalworkforce.

AddingvaluetothehealthandsocialcareprioritiesoftheGreaterManchesterpopulation,Ed-Citywillbuildbespokeprogrammesspecificallydesignedanddeliveredtomeettheevolvingneedsofournursingandalliedhealthprofessionalworkforce.

Insodoing,wewillcreatealearningenvironmentthatnotonlyattractsindividualstoourlocalUniversitiesviaauniqueeconomyofscalebutalsoprovideslife-longprofessionallearningandresearchopportunitiestoensuretheseindividualsareattheforefrontofthediscovery-carecontinuumwellintothenextmillennium.

100+ 130+People attended our Translational Research Training

Day’

Members in our Research Programme

Manager Network

13,000Participants

in our Clinical Bioinformatics online course

900NHS Trainees

undertook our 4-year DClinSci education

programme

2827


InnovationandPrioritisationCommittee(IPMC):PEGmembers

wereinvolvementintheHInMInnovationandPrioritisationCom-

mittee(IPMC)workshop,todevelopthehealthandcare‘systems’

approachtoprioritisationofsystemlevelinnovations.Apublic

memberhasnownominatedandinpositionaspartoftheIPMC

Membership.

PEGmembersplayedakeypartinFuellingAmbitionCreatively

Together(FACT),thisinitiativewasdesignedforyoungpeopleto

showcasetheirideasfordigitalinnovationsintheworldofhealth.

PEGmemberssataspartofanexpertpanel,providingfeedback

andsupportforfurtherdevelopmentandrefinementofideas.

PEGmembersattendedtheHInMPatientSafety,Maternityand

NeonatalLearningSystemlauncheventtokickstartpublic

involvementandengagementagendaacrossPSCworkstreams.

ThePSCteamhavenowproducedaplanforpatientandpublic

involvementandengagementacrosstheirwork-streams.

PEGmembershavebeenworkingwiththeProgrammeManager

oftheEuropeanRegionalDevelopmentFundatHInMonHealth

2.0.Health2.0isameetupgroupfocusedoninnovationsin

thedeliveryofhealthcareandhealthrelatedtechnology.This

communityaimstoshare,discuss,showcaseanddevelopideasto

improvepatientcare.

ThedevelopmentofanEarlyDetectionandDiagnosticDementia

FrameworkforGreaterManchesterhasseenaPEGrepresentative

facilitatingandleadingdiscussionsofthePublicandInvolvement

workstream.

PEGmakeupanimportantpartofHealthInnovationManchester’s

InnovationPanel,offeringfeedbackoninnovationgrants/

applications.

PEGPublicCo-Chair(AlanCampbell)hascontinuedtoattendand

feedbackfromtheNationalAHSNInvolvementLeadsmeeting

andworkingtoinfluencethenationalagendaaroundinvolvement

andengagement

PUBLIC INVOLVEMENT AND

ENGAGEMENT IS CENTRAL TO ALL

OF OUR WORK PROGRAMMES

In 2017 / 2018 we have: Public involvement & engagement

HealthInnovationManchesterensurethatpatientandpublicvoicesareattheheartofresearchandinnovationacrosstheentiretranslationalpathway.

OurPatientExperienceGroup(PEG)continuestobeinvaluableresourcethatenablesustodeliverprogrammesandprojectswhicharegroundedinthelivedexperience.

Throughout2017/2018PEGmembershavecontinuedtobeinvolvedinawiderangeofworkunderpinnedbythefollowingobjectives:

Tobeanorganisationwhichvaluespublicinvolvementanddevelopsthecapacityandcapabilityofitsstafftoinvolve,bysupportingandpromotinginvolvementandengagement,withattentiontodiversityandinclusivity.

Toformpartnershipswithkeystakeholderstoenhanceourpublicinvolvementwork,proactivelysharingandacquiringlearningfromamongexistingnetworks.

Tomakepublicinvolvementandengagementcorebusinessbyembeddinginvolvementatalllevels.

Over2017/2018yearallHInMProgrammeLeadsandProjectsManagersreviewedtheirportfoliostomakeclearthepublicinvolvementandengagementaspectsandhavebeenfeedingthisbackinthroughthePEGgrouptoaccesstherequiredsupportforco-producingapproachestoHealthandImplementation.

PEGmembershavealsobeenworkingcloselywithHealthInnovationManchestercolleaguestohighlightingtheimportantofthePP&Eagendaandsupporttheorganisationtoworktowardsatrueco-productionmodel-whichisHealthInnovationManchester’sambition.

100+ 130+People attended our Translational Research Training

Day’

Members in our Research Programme

Manager Network

13,000Participants

in our Clinical Bioinformatics online course

900NHS Trainees

undertook our 4-year DClinSci education

programme

3029


MEETTHEHEALTHINNOVATIONMANCHESTERBOARD

Professor Ben Bridgewater

Chief Executive Officer -

Health Innovation Manchester

Sir David Dalton

Chief Executive

Salford Royal NHS Foundation Trust and Pennine Acute

Hospitals NHS Trust

Sir Mike Deegan

Chief Executive

Manchester University NHS Foundation Trust

Johnny Lundgren

Chair

Greater Manchester Academic Health Science Network

Dr Kiran Patel

Chair

Association of Greater Manchester Clinical

Commissioning Groups

Jon Rouse

Chief Officer

Greater Manchester Health and Social Care Partnership

Lord Peter Smith

Greater Manchester Combined Authority Leader

with responsability for Health and Social Care

Roger Spencer

Chief Executive

Christie NHS Foundation Trust, Chair of Clinical Research

Network

Malcolm Press

Vice Chancellor

Manchester Metropolitan University

Rowena Burns

Chair Health Innovation Manchester

Chief Executive Manchester Science

Partnerships

John Stageman

Chair

Bionow

Dame Nancy Rothwell

President

University of Manchester

Richard Topliss

Chair

Manchester Growth Company

Sir Howard Bernstein

Chair

GM Strategic Partnership Board and Manchester Academic

Health Science Centre

Ian Greer

Vice President of the University of Manchester

Dean - Faculty of Biology, Medicine & Health

www.healthinnovationmanchester.com

@healthinnovmcr

TheHealthInnovationManchesterboardbringstogetherawealthofexperience,expertiseandinsightfromNHSandsocialcare,academiaandindustry.

32

Amanda Risino

Managing Director

Greater Manchester Academic Health Science Network


FINANCIALPOSITION2017/2018

GMAHSN MAHSC HInM

£’000s £’000s £’000s

INCOME 5,700 1,164 6,865

EXPENDITURE

Health and Implementation 856 0 856

Informatics 454 0 454

Industry and Wealth 1,086 0 1,086

Utilisation Management 1,233 0 1,233

Research and Development 184 345 529

Research Domains 0 639 639

Corporate 1,082 141 1,943

TOTAL EXPENDITURE 5,615 1,125 6,740

NET SURPLUS 85 40 125

NOTES:

GMAHSN results are for the year ended 31 March 2018

MAHSC results are for the period 01 August 2017 to 31 March 2018

Health Innovation Manchester,Third Floor,

Citylabs,Nelson Street,

ManchesterM13 9NQ

t 0161 509 3840w: healthinnovationmanchester.com

33

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