JINDAL INSTITUTE OF MEDICAL SCIENCE

ANTIBIOGRAM

1/8/2014-1/9/2014

DEPARTMENT OF CLINICAL MICROBIOLOGY &INFECTION CONTROL

DR LAL PATH LABS

Dr Jayant BalaniJayant.balani@Drlalpathlabs.com9896539594,09899994898

Tips on using the antibiogram

• Antibiogram is based on the Hospital Flora & antibiotic sensitivity of isolates from Jindal hospital over last 1 month .

• Antibiogram is updated at regular intervals(3 months)• Antibiogram can used to guide the empiric therapy in treatment .

See the most common isolate from the sample type(Urine,pus etc) ,then see the antibiotic sensitivity of the isolate which may then be used to guide the empiric antibiotic be sensitivity.eg E.coli is the commonest isolate in urine samples from the hospital & Imipenem has the highest sensitivity for E .coli followed by Pipercallin tazobactum & Amikacin.

• Antibiotics being used in antibiotic panels are as per Guidelines from CLSI(Clinical laboratries standards Institute),2014.

Type of isolates(Urine)

E. coli

K. Pneumoniae

Pseudomonas sp

.

Acinetobact

or sp.

S. au

reus

Enterococcu

s .fae

calis

0

5

9

14

18

2318

9

14

0

97

PercentagePercentage

Type of isolates(Sputum & E.T)

E. coli

K. Pneumoniae

Pseudomonas sp

.

Acinetobact

or sp.

S. au

reus

Enterococcu

s .fae

calis

0

13

25

38

50

4

3026

6 7

1

PercentagePercentage

Type of isolates(Pus)

E. coli

K. Pneumoniae

Pseudomonas sp

.

Acinetobact

or sp.

S. au

reus

Enterococcu

s .fae

calis

0

13

25

38

50

1014

73

26

2

PercentagePercentage

Type of isolates(Blood)

E. coli

K. Pneumoniae

Pseudomonas sp

.

Acinetobact

or sp.

S. au

reus

Enterococcu

s .fae

calis

0

6

13

19

25

13

6

2

18

0

PercentagePercentage

Number of isolatesGram positive isolates

N=number of isolates

Gram negative isolates

N=number of isolates

Staphylococcus aureus

43 Escherichia coli 38

Enterococcus faecalis

05 Klebsiella sp. 57

Streptococcus sp. 02 Pseudomonas sp. 55

Coagulase negative staph.(CONS)

21 Acinetobactor sp. 11

MRSA(Methicillin resistant Staphylococcus)

40

MSSA(Methicillin sensitive Staphylococcus sp.)

30

GRAM POSITIVE SENSITIVITYStaphylococcus,Enterococcus,Streptococcus

n=number of isolates

Antibiotic Sensitive (n)

Resistant (n)

% Antibiotic Sensitive (n)

Resistant (n)

%

Gentamycin 45 25 64% Amikacin 43 27 62%

Amoxyclave 35 25 58% Imipenem 43 27 61%

Azithromycin 42 28 60% Vancomycin 63 07 90%

Erythromycin 48 22 68.5% Linezolid 70 0 100%

Clindamycin 60 10 85%

Ciprofloxacin

31 39 44%

Antibiogram(Gram positive isolates)Li

nezo

lid

Vanc

omyc

in

Clin

dam

ycin

Eryt

hrom

ycin

Imip

enem

Azith

rom

ycin

Amik

acin

Imip

enem

Gent

amyc

in

Amox

ycla

ve

Cipr

oflox

acin

Ampi

sulb

acta

m

Levo

floxa

cin

Teic

opla

nin

0

25

50

75

100

125

10090 85

6861 60 62 61 64 62

40

8692

100

% sensitivity

GRAM NEGATIVE SENSITIVITYE.coli,K.pneumoniae.Citrobactor sp,Enterobactor sp.)

n=number of isolates

Antibiotic Sensitive (n)

Resistant (n)

% Antibiotic Sensitive (n)

Resistant (n)

%

Amikacin 62 32 65% Colistin 21 2 91%

Ampicillin/sulbactum

39 55 41% Imipenem 112 11 91%

Ceftazidime 16 19 45% Cefotaxime 43 57 43%

Ciprofloxacin 42 57 42% Ceftriaxone 33 62 34%

Cefuroxime 10 60 14% Aztreonam 32 64 33%

Meropenem 47 67 41% Piperacillin tazobactum

48 32 60%

Antibiogram(Gram negative)(E.coli,K.pnem,Citrobactor,Enterobactor)

Amik

acin

Cefta

zidim

e

Cipr

oflox

acin

Mer

open

em

Colis

tin

Cefo

taxi

me

Ceftr

iaxo

ne

Imip

enem

Pipe

raci

llin/

tazo

bact

um

Tica

rcill

in/c

lauv

anic

Ampi

cilli

n/su

lbac

tun

Cefu

roxi

me

Aztr

eona

m

Cefip

ime

0

25

50

75

100

65

45 42 41

91

4334

91

60

12

41

14

33

21

% sensitivity

GRAM NEGATIVE SENSITIVITYPseudomonas sp.

n=number of isolates(55)

Antibiotic % Sensitivity Antibiotic % Sensitivity

Amikacin 88% Cefoperazone /Sulbactum

70%

Ceftazidime 88% Imipenem 96%

Ciprofloxacin 53% Piperacillin /Tazobactum

67%

Meropenem 45% Ticarcillin/Clauvanate

34%

Colistin 100%

Cefotaxime 54%

Antibiogram(Pseudomonas sp.)Am

ikac

in

Cefta

zidim

e

Cipr

oflox

acin

Mer

open

em

Colis

tin

Cefo

taxi

me

Cefo

pera

zone

/sul

bact

um

Imip

enem

Pipe

raci

llin/

tazo

bact

um

Tica

rcill

in/c

lauv

anic

Tobr

amyc

in

Levo

floxa

cin

Gent

amyc

in

Cefe

pim

e

0

25

50

75

100

125

88 88

5545

100

5463

96

67

34 32

48 4638

% sensitivity

Multidrugresistant organisims(MDROS)

• MRSA-4O%• VRE-0• ESBL-55%• CRE-5%

THANK YOU