antibiotic recovery protocol - jenngibbons.com

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Antibiotic Recovery Protocol Antibiotic Recovery Treatment It’s important to follow antibiotic treatment with as much good gut support as possible. This will lead to a lower likelihood of Clostridium difficile, C. diff, and adverse impacts from antibiotics. I typically suggest plenty of fermented foods, fermentable fiber, soil-based organisms like Prescript-Assist and something with Saccharomyces boulardii in it; either take it alone or in a product like ABX Support from Klaire Labs, which has Saccharomyces boulardii, Lactobacillus rhamnosus, Bifidobacterium bifidum, and Bifidobacterium breve. All of these have been shown to support the normal gut flora after antibiotics. I recommend taking them during antibiotic therapy, away from when the patient is taking the antibiotics, so if the antibiotics are taken with meals, the probiotics should be taken away from meals, as well as taking them afterwards for several weeks. In addition to all of this, I’d suggest plenty of bone broth to help nourish the gut, enterocytes, and generally provide a more favorable environment for the re- establishment of healthy gut bacteria. Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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Page 1: Antibiotic Recovery Protocol - jenngibbons.com

Antibiotic Recovery Protocol

Antibiotic Recovery TreatmentIt’s important to follow antibiotic treatment with as much good gut support as possible. This will lead to a lower likelihood of Clostridium difficile, C. diff, and adverse impacts from antibiotics. I typically suggest plenty of fermented foods, fermentable fiber, soil-based organisms like Prescript-Assist and something with Saccharomyces boulardii in it; either take it alone or in a product like ABX Support from Klaire Labs, which has Saccharomyces boulardii, Lactobacillus rhamnosus, Bifidobacterium bifidum, and Bifidobacterium breve. All of these have been shown to support the normal gut flora after antibiotics. I recommend taking them during antibiotic therapy, away from when the patient is taking the antibiotics, so if the antibiotics are taken with meals, the probiotics should be taken away from meals, as well as taking them afterwards for several weeks. In addition to all of this, I’d suggest plenty of bone broth to help nourish the gut, enterocytes, and generally provide a more favorable environment for the re-establishment of healthy gut bacteria.

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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ClassificationofFibers

Thedifferenttypesoffiberhavealsobeencharacterizedintermsoftheirwatersolubility. There are solublefibersandinsolublefibers. The most important thing here is how fermentable a fiber is.

FermentableFibers

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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Inthediet,fermentablefibersarefoundprimarilyinfruits,vegetables,legumes,starchyplants,nuts,andseeds,butnotallfermentablefibersarecreatedequal.

Resistantstarchmaybeparticularlybeneficial;it’sfoundincookedandcooledpotatoes,rice,lentils,andgreenplantains,aslongastheyhaven’tbeencooked.Theproblemis,wedon’teatmanyofthehigh-fiberwildplantsourancestorsate.Theyconsumedoverahundredspeciesofplantsonaverage,whereasmanypeopleintheUSandEuropeeatmaybe15to20,andalotofthosedon’thavesignificantamountsoffermentablefiber,becauseovertimealotofthespeciesofplantsthatweeathavebeencultivatedtobecomesweeterandmoreenergy-denseandlessfiber-dense.

Sowhyisfermentablefibersoimportanttorestoringthegutecosystem?Well,itselectivelystimulatesalimitednumberoffavorablespecies,inparticularLactobacillusandBifidobacterium.Fiberincreasestheproductionofshort-chainfattyacids,increasestheacidityofthecolon,andmakesitlesshospitabletopathogensandmorehospitabletothebeneficialspeciesofbacteria,whichiswhyit’ssoimportantinthatsteptwoofthehealingthegutprotocol,whichiswherewerebuildandrestoreahealthygutecosystem.Short-chainfattyacidsalsopromotecelldifferentiationandproliferation,theyregulatesodiuminwaterabsorption,theyenhancetheabsorptionofcalciumandotherminerals,andfinally,fermentablefiberalsoimprovesgutbarrierfunctionandhostimmunity.

Prebiotics

Itcanbedifficultinthemoderndiettogetenoughfiber,andmanyofusdon’teatthevarietyofwildfibrousplantsandtubersthathunter-gatherersate.Probioticshavereceivedalotofattention,butprebioticsarearguablymoreimportantasinterventions.Probioticsdon’tquantitativelyimpactthegutfloraovertime,whichmeansthatonceyoustoptakingtheprobiotics,ifyouweretomeasurethegutmicrobiota,youwouldn’tseeanincreaseintheamountsofbeneficialbacteriafrompriortothetimethatthepatientstartedtakingtheprobiotics.That’sbecausemanyspeciesofprobioticsthataretakenaretransientresidentsofthedigestivetract.Theydon’tcolonizethegutandtakeupresidence,sotakingprobioticsdoesn’tactuallyincreasethenumbersofbeneficialbacteria.Theydohavealotofotherbeneficialroles,butincreasingthebeneficialbacteriaquantitativelyovertimeisnotoneofthem.

However,prebioticsdoincreasethebeneficialbacteriaovertimebecausetheyprovidefoodforthosebeneficialspecies,whichcanthenmultiplysothatapatientcouldincreasetheirbeneficialbacteriaovertime,stoptakingtheprebiotic,andthosenumberswouldstayincreasedprovidedthey’restillconsumingenoughfermentablefibertofeedthosebacteria.Sowetypicallysuggestrotatingbetweendifferentclassesoffermentablefibers.

Therearethreeclasses:solublefiber,non-starchpolysaccharides,andresistantstarch.Mostinsolublefibersarenotsignificantlyfermented.Alotofgrainfibers,forexample,likeinbran,brancereal,andbranmuffins,areinsoluble,andtheydon’thavethesamebeneficialimpactsofthesefermentablefibers.

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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Solublefiber

It’sbesttoleratedbypatientswithgutissuesingeneralbecausethey’renotFODMAPs(longerchainfoods/moredifficulttoassimilatefoods)andtheytendtohaveasoothingeffectonthedigestivetract.

Mostsolublefibersformagel-likesubstance,they’remucilaginous,sothatgel-likesubstancecoatsthedigestivetractandthat’swhatcanmakeithelpfulincasesofbothconstipationanddiarrheaandwithotherdigestivesymptomslikegasandbloating.

ThesolublefibersIliketousemostincludeglucomannan,whichiskonjacroot,andpartiallyhydrolyzedguargum.

Glucomannanisverywelltoleratedandhastheaddedbenefitofbloodsugarregulation.PGXisthebrand-namefiberthatyoumighthaveheardofthatcontainsglucomannan,orkonjacroot,anditcanbetakenin capsuleorpowderform,andtherearemanydifferentbrandsbutwetendtousetheNowbrand ofglucomannan.

Partiallyhydrolyzedguargumisasolublefiber,butunlikeothersolublefibers,it’snotviscous;itdoesn’tformthatgelinthegut.Thismakesiteasiertomixwithwaterandfoodandlesslikelytocausebloatingthat’sassociatedwithsomesolublefibers.It’sthebest-toleratedfiberI’veworkedwithofanyofthefibers,especiallyforpatientswithFODMAPintoleranceandwhodon’ttypicallydowellwithfiber.

Otheroptionsforsolublefiberincludepsylliumandacacia.Psylliumiswhat’sfoundincommercialproductslikeMetamucil.ItcanworkwellbutI’vefoundthatitcausesbloatinginmanypatients.Youcanbuypureorganicpsylliumonline,whichIthinkisbetterthanMetamucil,whichhassugarandartificialflavors.

Acaciafiberisfromtheacaciatree.It’salsogenerallywelltoleratedandhaslessofatendencytocausebloatingandgasthanothersolublefiberslikepsyllium,anditcanbepurchasedaspureorganicacaciafiberfromNowandothercompanies.Allofthesefibersarecheapandaffordable,whichisanotherbenefit.

Anothergoodoptionismodifiedcitruspectin.Pectin’sanaturallyoccurringsubstancefoundonthecellwallsofmostplants,andit’sespeciallyconcentratedinthepeelandpulpofcitrusfruits.Pectinisthenmodifiedtobreakdownitslong-branchchainofpolysaccharidesintheshorter,unbranchedlengthsofsolublefibermoleculesthatwilldissolveeasilyinwater.Ithassomedistinctproperties;it’sbeenusedtopreventcancer,metastasis,andbindheavymetals,especiallywhencombinedwithanalginatecomplexlikeinproductssuchasPectaSol.Andlikeothersolublefibers,it’sgenerallywelltolerated,butIthinkyoushouldadvisepatientstostartslowlybecauseofpotentialdetoxreactionsiftheyhavetoxinspresent.

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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Sowhichsolublefibersshouldyouchoose?

Theycanallhavethedesiredeffect,whichisgrowingbeneficialgutfloraandrelievingbothconstipationanddiarrhea.Butwhichisuseddependsonthepatientresponseandneeds.Sowewillgenerallystartwithpartiallyhydrolyzedguargum,PHGGforshort,orglucomannanifthepatienthasbloodsugarorweightregulationissues.There’snoreasonnottotrymorethanoneandrotate,whichwealsoadvise;it’sareallykeyconcept.

Resistantstarchgotreallypopularforawhileinthefunctionalmedicineandancestralhealthcommunity,andpeopleweretakinglargeamountsofitalone.Myconcernwiththatisthatstudieshaveshownthattakinglargeamountsofresistantstarchaloneactuallydecreasesthediversityofthegutflora,whichisdefinitelynottheoutcomethatwe’relookingfor,sorotatingthedifferenttypesoffiberwillmimicanancestraldiet.AsIsaid,hunter-gathererstypicallyatealotofplants,theyatealotoffiber,buttheywereexposedtoalotofdifferenttypesoffiber,notjustone,soontherebuildinghealthygutprotocolhandoutwe’regoingtogiveyouinthepatienthandout,you’llseethatwe’relistingmanyofthesedifferentfibersandwe’readvisingpatientstorotatebackandforth.Theydon’tnecessarilyneedtotakeallofthemeveryday,butrotatingbackandforthisagoodidea.

Non-starchpolysaccharides

SothisisalargecategorythatincludesinulinandFOS,forfructooligosaccharides,whichareasubcategoryofinulin,larcharabinogalactan,galactooligosaccharides,andbeta-glucan.

ManyoftheseareFODMAPs,sothey’rethemostlikelytocausegas,bloating,andGIdistress,especiallyinpatientsthatareFODMAP-intolerant.

Galactooligosaccharides,ofallofthese,tendtoproducetheleastamountofgas,andthey’retechnicallynotFODMAPs,sotheymaybethebesttoleratedofthenon-starchpolysaccharides,and

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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theyhaveoneofthebestprofilesintermsoftheirabilitytoincreaseBifidobacteriaandLactobacillus.IknowthanGlennGibson,who’saresearcherinthisfield,hewasactuallythepersontocointheterm“prebiotic,”heprefersgalactooligosaccharidesasaprebiotic.

Larcharabinogalactanisahighlybranchedpolysaccharideconsistingofagalactanbackbonewithsidechainsofgalactoseandarabinosesugars.It’sbeenshowntoincreasetheproductionofshort-chainfattyacids,especiallybutyrateandpropionate,andthey’vebeenshowntodecreasethegenerationandabsorptionofammonia,whichisabyproductofbacterialmetabolismandisoftenelevatedindysbioticconditions,andalsoinconditionslikeautismspectrumdisordersandmitochondrialdisorders.Ithasasignificanteffectonenhancingthebeneficialgutmicroflora.Specifically,itincreasesanaerobessuchasBifidobacteriaandLactobacillus.Italsohasanimmune-regulatingeffect;itcanstimulatenaturalkillercellcytotoxicity,enhanceotherfunctionalaspectsoftheimmunesystem,andinhibitmetastasisoftumorcellsintheliver.It’sbeenshowntobeusefulindecreasedimmunefunction,decreasednaturalkillercellactivity,orchronicviralinfection.

Beta-glucan,or 𝛽-glucan,isasolublefiberthat’sreadilyavailableinoatandbarleygrains;alsoin certaintypesofmushrooms,likereishi,shiitakeandmaitake;yeast;seaweed;andalgae,andstudieshaveshownthatitcanplayabeneficialroleinreducinginsulinresistance,dyslipidemia,hypertension,andobesity.Likelarcharabinogalactan,beta-glucanhasbeenshowntohaveanimmunoregulatoryeffect.Somebeta-glucansinteractwithimmunecellsandstimulatetheimmunesystemdirectly,whereasothersregulatetheimmunesystemastheypassthroughtheintestinaltract.Bacteriacanfermentbeta-glucansintheintestinaltract,andtheyproduceshort-chainfattyacidsandhaveanoverallprebioticeffect.

Nextisinulinandoligofructose,alsoknownasfructooligosaccharide,orFOS.Inulinisatermappliedtoavarietyoffructosepolymersfoundincertaintypesofplants,likewheat,onions,bananas,garlic,andchicory,amongothers.Oligofructoseisasubgroupofinulinconsistingofpolymerswithadegreeofpolymerization,orDP,below10.InulinandoligofructosearenotdigestedintheupperGItract,sotheybecomefoodforbeneficialbacteriainthecolon,especiallyBifidobacteria.InulinandFOShavebeenshowntoincreasestoolfrequency,increasestoolweight,anddecreasestoolpH.TheyalsodecreasetriglyceridesandtotalandLDLcholesterol.InulinandFOSareoftenaddedtofoodsasfunctionalfibers,andaswithotherFODMAPfibers,theyarepotentstimulatorsofBifidobacteria,buttheyarealsothemostlikelytocauseGIsymptomslikegasandbloating.

Galactooligosaccharides,orGOS,isacollectivetermforagroupofcarbohydratescomposedofoligogalactose,withsomelactoseandglucose.OligosaccharidesresemblingGOSoccurnaturallyinhumanmilkandmaybeoneofthefactorsthatprotecthumaninfantsfromgastrointestinalpathogenicbacteria.Theypassundigestedintothecolon,wherebacteriahydrolyzeandfermentthem,andthey’restrongpromotersofBifidobacteriaandLactobacilli.They’vebeenshowntoprotectagainstentericinfections,increasemineralabsorption,regulatetheimmunesystem,preventallergiesandgutinflammatoryconditions,increaseshort-chainfattyacids,addbulktothestool,andprotectagainsttoxinsthatmaypromotecoloncancer.Unlikeothernon-starchpolysaccharides,GOStechnicallyarenotFODMAPs,asImentioned,andmaybebettertolerated.

Inmyexperience,thisistrueinsomepatientsbutnotinothers.Itcanstillcausesignificantgasandbloating,sotheonlythingyoucandohereisjustadvisethepatienttoexperimentandseehowtheyrespond.

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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Sohere’sasummaryofthenon-starchpolysaccharideoptions.Irecommendtwoproducts,BiotaGenandGalactoImmunefromKlaireLabs,andifyoutakebothoftheseproducts,itcoverstheentirespectrumofnon-starchpolysaccharides,soyoucanusethemtogetheroryoucanrotatethembackandforth,andremember,patientswithSIBOandFODMAPintolerancethataren’ttakingantimicrobialsshouldprobablynotusetheseFODMAPs,becausetheycouldcontributetoarecurringSIBOcondition,butyoucouldtrystartingalowdoseandbuildingslowly.Thisisoneofthebiggestchallengesthatwefaceasclinicians,isthatweknowthatourpatientsneedhigherfiberintaketosupporthealthygutflora,andyetmanypatientswithgutissuesarenotabletotoleratehigherfiberintake,soyoureallyjusthavetohavethemexperimentwiththedifferentfibersandchoosetheonesthattheyareabletotoleratemostandeatmoreofthosetypesoffiber,andofcoursecontinuetoaddresstheunderlyingconditionsasmuchaspossible.

ResistantStarch

Thisisatypeofstarchthat’snotdigestedinthesmallintestineorthestomach,anditreachesthecolonintact.Althoughitisastarch,itdoesnothaveanyimpactonbloodsugarforthisreason.It’snotbrokendownintoglucoseanditdoesn’thitthebloodstream,soitdoesn’thaveanyeffectonbloodsugar.AsIsaidbefore,it’saninsolublefiber,butunlikeotherinsolublefibers,whichgenerallyaren’tfermentedmuchbycolonicbacteria,resistantstarch,orRS,is.

Therearefourdifferenttypesofresistantstarch.

There’sRS1,whichisindigestibleandfoundingrains,seeds,andlegumes.

There’sRS2,whichisastarchwithhighamylosecontent;itisalsoindigestibleintherawstatebutbecomesdigestiblewhenit’scooked,andthisisthetypethat’sfoundinpotatoes,greenbananas,andgreenplantains,socookingthesefoodscausesthechangesinthestarchthatmakeitdigestibleandremovetheresistantstarch,whichiswhyyouhearsomuchdiscussionabouteatingcooked

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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andcooledpotatoesoreatingdehydratedgreenplantainsorgreenbananas,becauseifthey’reuncookedorthey’recookedandthey’vebeencooled,that’swheretheresistantstarchisfound.

RS3isalsocalledretrogradeRS,sincethisisthetypeofresistantstarchthatformsaftertypeoneortypetworesistantstarchiscookedandthencooled,sowejusttalkedaboutthat.Thesecookedandcooledfoodscanbereheatedatlowtemperatureslessthan130degreesandmaintainthebenefitsofRS.Soexampleswouldincludecookedandcooledparboiledrice,whiterice,cookedandcooledpotatoes,andcookedandcooledandproperlypreparedlegumeslikelentils.

Finally,RS4isasyntheticformofresistantstarchthatI’mincludingforcompletenessbutwouldnotrecommend;acommonexampleofthiswouldbehigh-maizeresistantstarch.

Severalstudieshavelookedattheimpactofresistantstarchongutfloraandhealth.Likeotherprebiotics,resistantstarchselectivelystimulatesthegrowthofbeneficialspecieslikeBifidobacteriaandLactobacillus.Italsoincreasestheconcentrationofshort-chainfattyacidslikebutyrateandpropionate,andit’sbeenshowntoprotectagainstcoloncancer,improvemetabolichealth,reducefastingbloodsugarandbodyweight,andimproveinsulinsensitivity.AndI’veseenbigchangesthereactuallywithresistantstarch;I’veseenreductionsinfastingbloodsugarofupto10milligramsperdeciliterormoreinsomecases.Empirically,resistantstarchcanalsohelpwithsleepandmood,sopatientswhohaveinsomnia,depression,anxiety,issueslikethatcanactuallyimprovewithresistantstarch,andthateffectispossiblymediatedviathegut-brainaxis.AsImentionedafewslidesback,somestudieshaveshownthathighintakesofresistantstarchwithnootherfiberscanactuallydecreasethediversityofbeneficialbacteriaspeciesinthegut,whichisdefinitelytheoppositedirectionthanwewanttogo,soresistantstarchshouldalwaysbepartofawiderspectrumoffiberintake.

TheeasiestwaytosupplementwithresistantstarchaboveandbeyondthefoodsthatIjustmentionedisgluten-freeunmodifiedpotatostarch—Bob’sRedMillisagoodbrand—orgreenbananaflourorgreenplantainflour.Soyoucouldaddthistosmoothies,butnotsoupsbecauseyoudon’twanttocookit;thatwouldinactivatetheresistantstarch.Youcanalsoeatthefoodswetalkedabout,whitepotatoes,whiteparboiledriceorlentilsthathavebeencookedandcooled,andthereisacommercialproductcalledPrebioticPluswithpotatostarchandgreenbananaflour.Thedoseofthepotatostarchofthecommercialproduct,actuallyI’mnotsureofthedoseofthecommercialproductbecauseIhaven’tuseditmuch,butforpotatostarchitwouldbetwotofourtablespoonsadayofpotatostarchorgreenplantainflourforamaximumtherapeuticeffect.However,donotstartthepatientthere;youhavetostartreallyslowly,maybeaquartertoahalfteaspoonperday,becauseitcanproduceprettyintenseGIsymptoms;aquartertohalfteaspoonperday,andthemoreGIsymptomstheyhave,themorecarefulandcautioustheyneedtobe.

Thebiggestclinicalchallengeofprebioticsandfermentablefiberisthatthepeoplewhoaremostlikelytoneedthemarealsotheleastlikelytotoleratethem.Thelow-FODMAPdietreducestheintakeofmanyofthesefibersandhasbeenshowntorelievesymptoms,butwhatarethelong-termconsequencesofthelow-FODMAPdiet?Wealreadyhavesomestudiesshowingthatthelong-termlow-FODMAPdietreduceslevelsofbeneficialbacteriainthecolon.Thisisobviouslynotideal;wemayendupfixingoneproblem,likeSIBOorIBS,andcausinganother,whichcouldbeincreasedsusceptibilitytoawidevarietyofchronicmoderndiseases.Soourapproachintheclinicisatwo-stagetreatmentwhereweaddresstheunderlyingpathologiesthatcausethesegutsymptomsandthenwerebuildahealthygutecosystem.Soforexample,ifapatienthasSIBOandthat’scausingthe

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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fiberandFODMAPintolerance,thenwetreatitandslowlyreintroducethebeneficialfibersovertime.

Probiotics

Animportantconcepttounderstandisthatrecentstudieshaveshownthatwhileprobioticsarebeneficial,theydon’tworkbyquantitativelyincreasingthegoodgutbacteria.Wetalkedaboutthisbeforeinthepresentation,butIwanttoemphasizeithereagain.Ithinktypicallypeoplehavethoughtofprobioticsaslikebeneficialbacteria;it’smaybelikethegastankanalogy,likeifyouhavelowlevelsofbeneficialbacteria,probioticswillkindoffillupthetankandtakeyoufromhavinglowamountstohavinghighamounts.Butwenowknowthatthat’snotreallyhowprobioticswork.Theyworkbytransiently,meaningtemporarilyaslongasyou’retakingthem,tuningandregulatingtheimmunesystem,promotinganti-inflammatorypathwaysandcreatingafavorableenvironmentforbeneficialbacteria.Anotherwaytothinkaboutitisthatprebioticsincreasewhat’salreadythereandprobioticsregulatewhat’salreadythere.

Fermentedfoods

Humanshavealonghistoryofconsumingfermentedfoods.AccordingtoProfessorKeithSteinkrausatCornell,“TheprocessesrequiredforfermentedfoodswerepresentonEarthwhenmanappearedonthescene.Whenwestudythesefoods,weareinfactstudyingthemostintimaterelationshipswithbetweenman,microbeandfoods.”Sothesefoods,likehoney,berries,fruit,andfruitjuices,wereconsumedvery,veryearlyon,probablybeforewewereevenhuman,definitelyourprimateancestorsstillconsumedthem.FermentedfoodsareaboutasPaleoorancestralasyoucanget.Withoutknowinganythingaboutmicrobes,ourancestorsrecognizedthetherapeuticqualitiesofthesefoods,andvirtuallyallcontemporaryhunter-gatherersthathavebeenstudiedconsumesomekindoffermentedfoods.

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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MeasurementsofthechemicalcontentwithinancientNeolithicvesselssuggestthatintentionalfermentationoffruit,rice,orhoneybeverageshasbeencommonpracticeforcloseto10,000years.Therearenumerousreferencestoalcoholproductionduringantiquity,butwealsoknowthatfermentationofcereals,dairy,vegetables,fish,seafood,andmeatswasasignificantpartofancestraldietarypractices.

Fermentedfoodshaveseveraladvantagesovercommercialprobioticproducts.First,asImentioned,hominidshavebeeneatingfermentedfoodsformorethan2millionyears,andwe’readaptedtogettingmicrobesfromthesefoodsforthisreason.Second,there’ssomeevidencethatprobioticbacteriainfoodsmaybebetterabletosurvivethestomachacid.Thisisoneproblemwithmanycommercialprobiotics.Onestudyshowedthat35percentofalllacticacidbacteriaisolatedfromrawfruitsandvegetablescansurvivegastricconditions.Third,fermentedfoodhasotherbenefits;itincreasesthebioavailabilityofmood-regulatingBvitamins,magnesium,andzinc,anditmayimprovevitaminDstatus.

Fourth,theconcentrationofprobioticorganismsissignificantlyhigherinsomefermentedfoods.Forexample,onecupofkefircontainsapproximately2.35trillioncolony-formingunits,orCFUs.Comparethattomostprobioticsupplementsthatonlyhaveafewbillion,andeventhehigh-potencyproductslikeVSL-3orElixathathave500billion,andthisisespeciallytrueforhomemadefermentedfoodsthatyoucanfermentforlongerperiodstoincreasetheirmicroorganismcontent.Finally,fermentedfoodsaremuchcheaperthancommercialprobiotics;youcanmakereallylargebatchesofsauerkraut,andonlyusingcabbage,whichisoneofthecheapervegetables. Someofthemostcommonfermentedfoodsincludekefir,thatcanbemadefrommilkorwaterorcoconut,youngcoconutwater;yogurt;sauerkraut;kimchi;beetkvass;andkombucha.Clinically,Ifoundkefirtobethemosttherapeutic,especiallyhomemadekefirmadefrompasture-raisedorganicmilk,ifpatientscantolerateit.It’srichinbeneficialmicrobes,anditalsocontainsfat-solublevitaminslikevitaminAandK2,andnaturaltrans-fats.Notethatevenpatientswithlactoseintolerancecanoftentoleratekefirwhenit’sbeenfermentedfor24hoursbecausethatvirtuallyeliminatesthelactose.Also,studieshaveshownthatkefirmaybeabletoreverselactoseintolerance;inotherwords,thepatientislactoseintolerantandtheyconsumesmallamountsofkefirandgraduallyrampitupovertime,andtheyactuallybecomeabletotoleratelactose.Soifapatientisintoleranttotheproteinsindairy,however,theyprobablystillwon’tbeabletotoleratekefirbecausethefermentationdoesn’tchangetheproteinssignificantlytochangetheantigenicityofthemilk,buttheycanmakekefirfromwaterorcoconutwaterorotherbeverages.

FermentedfoodsprovidehugeamountsoflacticacidbacterialikeLactobacillus,BifidobacteriaandStreptococcus.We’vebeenconsumingthesestrainsformillenniaandthey’realsoverywellstudied.Fermentedfoodsareamoreconcentratedsourceofthesetypesofbacteriathancommercialproducts.

Aboveandbeyondthelacticacidbacteria,I’drecommendaproductwithsoil-basedorganisms.Upuntilveryrecently,allhumans—andstilltoday,mosthumansthatliveinruralareasonfarmsandinthedevelopingworld—consumedmilligramquantitiesofthesetypesofbacteriathatarefoundinsoilandwater.TheyincludespeciesfromtheBacillusgenus,whichisagut-adaptedendospore-formingbacteriathatsurvivesthestomachacidcompletelyintactandhasnumerousbeneficialeffectsincludingantimicrobialproperties.It’snotaseasytoconsumetheseinthedietasitistogetlacticacidbacteriathatwegetfromfermentedfoods.Youcouldeatunwashedfruitsandvegetablesandalittledirt,butthat’ssomewhatproblematicgivenallthetoxinsthatarefoundinsoiltoday,soIthinksoil-basedorganismsthathavebeenisolatedareabetteroption.

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]

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Thereareseveralproductsoutthere,thingslikePrimalFlora,PrimalDefense,AOR3,andPrescript-Assist.Prescript-AssististheoneI’vehadthebestsuccesswithandhavethemostexperiencewith.It’sabroad-spectrumprobioticwith29differentstrains,it’sshelf-stablesoitdoesn’trequirerefrigeration,veryeasytotravelwith,survivesthestomachacid,it’shigh-potency,itcontainsaprebioticcalledleonardite,andit’ssupportedbylong-term,peer-reviewed,double-blind,placebo-controlledtrials,whichismorethanmostprobioticscansayforthemselves.Notethatsoil-basedorganismsingeneralandPrescript-Assistinparticularareoftenwelltoleratedevenwithpatientsthatdon’tdowellwithlacticacidprobiotics.AgoodmaintenancedosewithPrescript-Assistisonecapsuleperday.

Prescript-Assistmicrofloraarerecognizedasclass-oneetiologicalagents,whichmeansthey’renon-toxicandnon-pathogenic.Morethanadecadeofuseasasupplementhasrevealednoadverseeffectsand/orsideeffects,includingreportedlypatientswithimpairedimmunesystems,aswellastheinitialdemonstrationswithrepeatedconsumptionsofdosesamountingto500timestherecommendedhumandoseforordinarydailyuseinanimalstudies,bytheway,withnoilleffect.Incaseswherepatientscan’ttoleratefermentedfoods,youmaywanttosuggestalacticacidprobioticforongoingmaintenance.Ther-BioticCompletefromKlaireLabsisagoodchoice,it’sabroadspectrumofbacteria,relativelyhighpotency,thoughnotashighasVSL#3andElixa,whicharemoretherapeutic-strengthprobiotics.VSL#3inparticularhasbeenverywellstudiedininflammatoryboweldisease,ulcerativecolitisinparticular,andothergutconditions,anditcanbeveryeffectivewhenpatientstolerateitwell.Theseproducts,becausethey’relacticacidbacteria,dorequirerefrigeration.

Jenn Gibbons, MSTOM, LAc - 646.801.6810 - [email protected]