antibody structure
DESCRIPTION
Antibody Structure. B cell activation. Antibody-Mediated E ffector Functions. Antibody Classes. Immunoglobulin G ( IgG ) Most abundant class Four subclasses Activate complement system. Antibody Classes. Immunoglobulin M ( IgM ) Pentamer 1 st class produced in response - PowerPoint PPT PresentationTRANSCRIPT
![Page 1: Antibody Structure](https://reader036.vdocument.in/reader036/viewer/2022070400/56812a9c550346895d8e59b7/html5/thumbnails/1.jpg)
Antibody Structure
![Page 2: Antibody Structure](https://reader036.vdocument.in/reader036/viewer/2022070400/56812a9c550346895d8e59b7/html5/thumbnails/2.jpg)
B cell activation
![Page 3: Antibody Structure](https://reader036.vdocument.in/reader036/viewer/2022070400/56812a9c550346895d8e59b7/html5/thumbnails/3.jpg)
Antibody-Mediated Effector Functions
![Page 4: Antibody Structure](https://reader036.vdocument.in/reader036/viewer/2022070400/56812a9c550346895d8e59b7/html5/thumbnails/4.jpg)
Antibody ClassesImmunoglobulin G (IgG)
Most abundant class Four subclassesActivate complement system
![Page 5: Antibody Structure](https://reader036.vdocument.in/reader036/viewer/2022070400/56812a9c550346895d8e59b7/html5/thumbnails/5.jpg)
Antibody ClassesImmunoglobulin M (IgM)
Pentamer1st class produced in responseto an antigenActivates complement system
![Page 6: Antibody Structure](https://reader036.vdocument.in/reader036/viewer/2022070400/56812a9c550346895d8e59b7/html5/thumbnails/6.jpg)
Antibody ClassesImmunoglobulin A (IgA)
Predominant class in secretions Secretory IgA
![Page 7: Antibody Structure](https://reader036.vdocument.in/reader036/viewer/2022070400/56812a9c550346895d8e59b7/html5/thumbnails/7.jpg)
Antibody ClassesImmunoglobulin E (IgE)
Hypersensitivity reactions
![Page 8: Antibody Structure](https://reader036.vdocument.in/reader036/viewer/2022070400/56812a9c550346895d8e59b7/html5/thumbnails/8.jpg)
Antibody ClassesImmunoglobulin D (IgD)
Major membrane-bound immunoglobulin expressed by mature B cells.
![Page 9: Antibody Structure](https://reader036.vdocument.in/reader036/viewer/2022070400/56812a9c550346895d8e59b7/html5/thumbnails/9.jpg)
Antigenic determinants on immunoglobulins
IsotypeAllotypeIdiotype
![Page 10: Antibody Structure](https://reader036.vdocument.in/reader036/viewer/2022070400/56812a9c550346895d8e59b7/html5/thumbnails/10.jpg)
Humoral and Cellular Immunity
•Cellular immunity – Host defenses that are mediated by antigen-specific T cells and various nonspecific cells of the immune system.
•Humoral immunity – Host defenses that are mediated by antibody present in the plasma, lymph and tissue fluids.