anticoagulants: research in development

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ANTICOAGULANTS

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Page 2: Anticoagulants: research in development

Anticoagulant medicines work by interrupting part of the

process involved in the formation of blood clots.

Blood clots are less likely to form where they are not

needed, but can still form when they are needed

Page 3: Anticoagulants: research in development

Deep Vein Trombosis

Pulmonary Embolism

Risk of a stroke

Atrial Fibrillation

Risk of developing Blood Clots

After Surgery

What are anticoagulants used for?

Page 4: Anticoagulants: research in development

YEARLY EXPENSES

In 2008, 6,2 billion US Dollars were spent on anticoagulants

In 2014, 9,1 billion US Dollars were spent on anticoagulants

LMWH

DTI

Heparin

Factor XainhibitorsWarfarin

Other

LMWH

DTI

Heparin

Factor XainhibitorsWarfarin

OtherSource: http://www.nature.com/nrd/journal/v8/n5/fig_tab/nrd2851_ft.html

Page 5: Anticoagulants: research in development

Warfarin has shown to reduce the risk of AF-

related strokes by 64% as opposed to 19% by Antiplatelets such as

Aspirin

Page 6: Anticoagulants: research in development

Due to serious side-effects, medicine optimisation is

necessary

The NOACs: Apixaban, Dabigatronetexilate & Rivaroxaban are the first major innovation in the

prevention of non valvular Atrial Fibration stroke in 50 years

http://www.abpi.org.uk/our-work/library/medical-disease/Documents/ABPI%20SAFI%20report.pdf

Page 7: Anticoagulants: research in development

Preventive stroke care will save governments enormous amounts of

money

Continuous optimisation

safer medicines

Page 8: Anticoagulants: research in development

Talentum BioTech offers customized molecular simulation and

bioactive compound discovery services to biopharma companies & academic

research groups

Talentum BioTech has experience in the field of Anticoagulants

Click on logo to directly visit our website (http://www.talentum-biotech.com/en/)