api hiv epidemiology, disparities, the hidden hiv epidemic · 2018. 10. 16. · 10/15/2018 2 asia...

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10/15/2018 1 APIs & the HIV Epidemic: Getting to Zero Health Disparities and Zero New HIV Infections Sophy Shiahua Wong, MD, AAHIVS Medical Director, Bay Area AIDS Education Training Center (AETC) & HIV ACCESS Internal Medicine/HIV/hepatitis primary care provider, Asian Health Services Associate Clinical Professor of Medicine, UCSF Objective: HIV, APIs, and Getting to Zero API HIV epidemiology PrEP, U=U, rapid ART resources API HIV epidemiology, disparities, the hidden HIV epidemic

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Page 1: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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APIs & the HIV Epidemic: Getting to Zero Health Disparities 

and Zero New HIV Infections

Sophy Shiahua Wong, MD, AAHIVSMedical Director, Bay Area AIDS Education Training Center (AETC) & HIV ACCESS

Internal Medicine/HIV/hepatitis primary care provider, Asian Health Services

Associate Clinical Professor of Medicine, UCSF

Objective:HIV, APIs, and Getting to Zero

API HIV epidemiology

PrEP, U=U, rapid ART

resources

API HIV epidemiology,disparities,

the hidden HIV epidemic

Page 2: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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Asia is behind Africa in access to HIV treatment & prevention: 

In 2017: • 36.9 million people living 

with HIV worldwide• 1 million deaths• No longer a top 10 cause of 

death worldwide (but is #4 in low‐

income countries)

WHO data, updated May 2018

US HIV prevalence, 2016

US CDC data, updated March 2018

Page 3: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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www.cdc.gov/hiv/pdf/programresources/cdc‐hiv‐npep‐guidelines.pdf  

Lifetime HIV risk: 1 in 2 Af Am MSM

API Wellness Center

US HIV testing guidelinesEveryone 13‐65! It’s covered!

USPSTF Grade A, 2013: ages 15‐65

CA HIV testing laws, 2013No written consent neededMandatory testing in primary care

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API Wellness Center

x

Page 4: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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Most APIs with HIV get it through sex:

CDC: HIV Among Asians, 2018

New HIV diagnoses are rising among APIs…

CDC: HIV Among Asians, 2018

…and APIs in Alameda County have the lowest median CD4 at the time of diagnosis:

"Alameda County HIV Surveillance Report, 2014‐2016," published March 2018.

But when in care, APIs in Alameda County have high rates of viral load suppression:

"Alameda County HIV Surveillance Report, 2014‐2016," published March 2018.

Page 5: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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The role of primary care in ending the HIV epidemic: 

Creative Commons license photosby Ali Yahya on Unsplashby Walt Stoneburner on Flickr

HIV testingPEPPrEP

& linkages!4th generation HIV testing!‐combined antigen‐antibody test‐shortens window period: 45 to 14 days‐can pick up acute HIV infection

Whom do you test for HIV?

John, a 20 year old Vietnamese   pre‐med drops in for “a check‐up”

Hdwallpapersarena.com

If John is HIV‐negative, what can you do to reduce his risk of getting HIV?

Hdwallpapersarena.com

Page 6: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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>99% effective if taken daily

Page 7: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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The Stigma Project

PleasePrEPme.org

PrEP: in one page!

Whom do you test for HIV?

Mrs. Cruz, 

a 65 year‐old grandmother comes in for diabetes follow‐up and needs to get her labs checked.

Photo: CC0 license

Mrs. Cruz’s 4th gen HIV test result:HIV Ag/Ab+

Multispot Differentiation Ab+

Photo: CC0 license

Page 8: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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What is HIV?

We’ve come a long way…

From this & many side effects…

We’ve come a long way…

…to 10 single‐tablet regimens& 6 classes of drugs

Treatment reduces HIV transmission by how much?

Page 9: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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treatment reduces transmission by

96%HPTN 052 study: Cohen MS et al, NEJM 2011: 365 HIV Plus Magazine, October 2017

Rapid ART ART

retention viral suppression 

survival

Koenig, AIDS 2016; Lifson 2017; Rosen 2016; Bacon 2018; Pilcher, JAIDS 2016 and 2017; Photo by Zun Zun from Pexels CDC, HIV Surveillance Report, 2015; vol. 27. Pub 11/2016; data updated 7/2018 

37,600+ new HIV diagnoses each year 

in the US

PrEP test treat

Page 10: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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APHA: “The Nation’s Health”

The Stigma Project

CDC: Act Against AIDS

Page 11: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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ZERO new infectionsZERO AIDS‐related deathsZERO discrimination

New York State

You can help us test, rapidly link people with HIV and offer PrEP!

Page 12: API HIV epidemiology, disparities, the hidden HIV epidemic · 2018. 10. 16. · 10/15/2018 2 Asia is behind Africa in access to HIV treatment & prevention: In2017: • 36.9 million

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Key points:APIs getting to zero new HIV infections!

• 1 in 5 APIs with HIV don’t know they have it.

• Test everyone for HIV once, and some annually. 

• Offer Rapid linkage/ART: treatment reduces transmission by 96%! 

• Offer PrEP! It’s >99% effective when taken daily.

• Collective impact makes a difference! 

test PrEP treat

Resources

1. HIV Clinical Essentials one‐page PDF

2. Clinical questions: HIV Warmline– nccc.ucsf.edu 

– Call 1‐800‐933‐3413

3. Training and technical assistance: AETC– www.paetc.org

– call 415‐476‐6153

– Email: [email protected]