application of computers in hospital and clinical pharmacy

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    CLINIC L PH RM CY SSIGNMENT

    2013

    Application Of

    Computers In Hospital

    And Clinical Pharmacy

    Pharm D 4th Proff Evening

    Group No 7

    J I N N A HU N I V E R S I T Y

    F O R

    W O M E N

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    Group

    Members

    (No. 7)

    1.Afshan

    Mushtaq

    10597 2.Ammarah

    Shaikh

    10604

    3.Asra Alvi

    10611

    4.Erum

    Akhter

    10617

    5.Halima

    Sadia 10628

    6.Hira

    Akbar

    10634

    7.Sualeha

    Batool Baig

    10681

    8.Syeda

    Kinza

    Mehmood

    10682

    9.Tuba

    Hasaan

    Qureshi

    10692

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    Table of ContentsABSTRACT: ..................................................................................................................................................... 4

    BACKGROUND: .............................................................................................................................................. 4

    INTRODUCTION: ..................................................................................................................................... 5

    DISCUSSION AND CONCLUSION: ................................................................................................................. 10

    REFERENCES: ........................................................................................................................................ 12

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    APPLICATIONS OF COMPUTER IN

    HOSPITAL AND CLINICAL PHARMACY

    Afshan Mushtaque, Ammarah Shaikh, Asra Alvi, Erum Akhter, Halima Sadia, Hira

    Akber, Sualeha Batool, Syeda Kinza, Tuba Hassan

    Students of 4thProfessional Pharm-D

    Jinnah University for Women

    ABSTRACT:

    Computers have become an important necessity for the pharmacist over the past decade who is

    engaged in drug information services, patient counseling etc so as to satisfy patient queries

    related to medicines including toxic effects, adverse drug reactions, and drug interactions and

    also about the disease, disorder, acute syndrome or new innovative therapies. The field of

    pharmacy is immensely benefited by the use of computer and it will continue to do so. The role

    of computers in hospital and clinical pharmacy is diversified. They help in patient record

    management, entry of medication errors, drug therapy monitoring, purchasing and inventory

    control, patient medication profile etc. Further development in computer technology will enable

    the pharmacist to discover new drugs for the complete care of dangerous of diseases like aids,

    cancer etc. and reduce the cost of production of drugs for diseases which are easily cured.

    Various hardware and softwares have been developed without which drug discovery, designing,

    manufacturing and analyzing would become virtually impossible.

    Computer and computerprograms are also aid in utilizing drug information. Thus, there are numerous applications of

    computer in clinical and hospital pharmacy and computers have become a necessary solution for

    optimizing patient care.

    KEY WORDS:

    Computers, drug information, softwares, hospital pharmacy, clinical pharmacy

    BACKGROUND:

    Utilization of computers in hospitals and clinical pharmacies started in United States in 1960s

    and has shown fast growth in 1980s. Different researches and studies have been conducted over

    the period of years to highlight the applications and beneficence of computers in hospital and

    clinical pharmacy and have contributed in further advancement in the use of computers in

    hospital and clinical pharmacy. With the passage of time the practice of using computers has

    gained considerable priority and have ease the pharmacists job. In this study weve focused the

    importance of computers in clinical and hospital pharmacist life.

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    INTRODUCTION:Pharmacy field plays a crucial role in patient healthcare. It is a huge field which is present

    worldwide. To run pharmacy field professionally and efficiently, it requires huge management

    and manpower. But now a days use of computers in pharmacy field reduced the manpower and

    time. Computers are almost related to every corner of pharmacy field. (Shivraj Jadhav, 2012)

    Initially the pharmacist was spending time dealing with customers and the business virtually took

    care of itself. Now, however, the costs (time and money) of doing business are forcing the

    pharmacist to spend a decreasing amount of time with the customers and more in attending

    administrative aspects of the pharmacy. (Murray MD, 1998) Moreover, the independent

    pharmacy owners face tough challenges in front of the growing customer demands and

    increasing competitive threats. The development of information technology in the 20th century

    brought with it significant impact on computerization of pharmacy. (Roberts MB, 2002)

    (Murray MD, 1998) (Carmichael JM, 2004)

    In Both Hospital and Community Pharmacies, Computer applications are used in conjunction

    with drug administration, ambulatory care, clinical practice and drug distribution. Computers

    have become the main component of pharmacy practice. It is essential for pharmacist and

    pharmacy technicians to become computer literate, and comfortable using the common software

    programs made for pharmacies. Computer can help in reducing error and potential patient harm

    by keeping information up-to-date, accessible, accurate, standardized, concise and correct.

    (Moini, 2010) (Shivraj Jadhav, 2012) With computers we can keep track of drug inventory,

    narcotics use, changes in the drug formulary and personnel. Computers are used for patient

    billing, insurance billing and verification, pricing, maintenance of patient profiles, generation ofmedication administration record and a number of computational an repetitive tasks. (M.D,

    2007)

    The amount of information used in pharmacy is huge. In addition to keeping up with the rapid

    changes in field, with new drugs and new delivery systems added every day, computers and

    computer programs are useful in utilizing new drug information. Computers can help to reduce

    medication errors with programs that are designed to alert the user of possible medication

    interactions or allergies, dose limitations, drug duplications, and other warnings. (Evans, 1998)

    For Example: A properly programmed computer can suggest the proper diluting agent (diluent)to use in preparing an IV , as some drugs are more compatible with particular diluents ~ e.g., NS

    as opposed to water or D5W as opposed to NS, etc. The computer may even also alert the

    pharmacist to potential drug-drug interactions and drug physiology interactions, which help to

    safeguard the patient. The pharmacists and physicians may also use computers (the portable palm

    computers) to track a patients laboratory results or monitor drug levels. Information can also be

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    passed back and forth from physician to pharmacist via these portable computers, making for

    optimal patient therapy.(Overhage JM, 1996) (Dexter, September 27, 2001) (Anthony, 2004)

    Using Computers in Continuing Education makes the computer an excellent tool for the ongoing

    education of pharmacy personnel. There are internet sites that present the latest drug information

    and monograph. In addition, computers can provide the pharmacist and technician with

    information on a particular topic, references, communication with researches and pharmaceutical

    companies.(Anthony, 2004)

    For Drug interaction screening, computer programs like MEDIPHOR (Monitoring and

    Evaluation of Drug Interaction by Pharmacy Oriented Reporting) and PAD (Pharmacy

    Automated Drug Interaction Screening) are made. Thus using computers can enhance the

    standards of a pharmacists clinical services. In addition to these services, pharmacists use

    computers for graphic printing, storage of multiple patient data for analyses and exact dosing of

    drugs following one compartment model.

    A frequently recommended method for preventing adverse drug events is computer-aided

    screening of prescriptions. Pharmacists generally screen, or perform prospective review, of a

    patient's medication regimen during the prescription dispensing process to prevent drug-related

    problems.(Bates DW, 1998)

    Computers play an important role in preventing medication errors. Several approaches have beenshown to decrease medication errors. Computerized physician order entry (CPOE) has been

    shown to decrease medication errors by 5580%. Computer applications allow clinical

    pharmacists to easily review orders and identify DRPs (Drug Related Problems). (Bates DW L.

    L., 1998) (Bates DW T. J., 1999) (Kuperman GJ, 2001)

    A complete search of drug information is necessary for the clinical pharmacist so as to satisfy the

    queries about pharmacology, drug interactions, adverse drug reactions, toxicology etc. This job

    of searching can be simplified by using computers. In 1964, National Library of medicinecreated a computerized medical information retrieval system MEDLARS (Medical Literature

    Analysis and Retrieval System). In 1971, they developed a fast working system MEDLINE

    (Medlars On-Line). (Paradkar, 2008)

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    A pharmacy computer system must assure that the pharmacys patient record database is

    continually updated to reflect the current status of all patients. This updating is done by assessing

    the database of admitting department to determine the information about recent admissions,

    discharges and patient transfers. The computer system should be capable of producing the other

    information such as: Present diagnosis, allergies, weight, height, name of attending physician andother special note about patient.

    Rapid processing of drug order is the essential function of computer system. Formatted data

    entry should allow easy entry and retrieval of orders. A pharmacist should be able to retrieve

    orders for review prior to administration to patient. Data may be entered by use of codes for drug

    name, dosing schedule.

    Preparation of lists is an another important aspect of computer use in hospitals. Like Fill-Lists for

    preparation of individual doses, List of medications charged, Drug Order Renewal lists for

    prescriber and Medication administration record (MAR).

    Computer as Data base is very beneficial as if the prescription containing many drugs is entered

    in the computer for billing purpose, immediately the computer scans the drug and issues the

    warning if there is possibility of drug interaction. Thus computer helps in avoiding the drugs

    duplication. The computer also issues the warning, if two or more brands of same drug are

    entered in it. Thus avoid the drug duplication. Whenever the pharmacist is very busy, he may

    pass on his work of displaying the content and instructions of medication and label printing to

    the computer after entering the prescription. This is useful in avoiding the human errors.

    The computer can be effectively used for purchasing and inventory control in the hospital

    pharmacy as maintenance of perpectual inventory control, Maintaining the inventory records,

    calculation of inventory, automatic updating of the price, evaluation of demand.(Yadav, 2007)

    (Richard, 2006) Whenever an item is added to stock or removed from stock, immediately the

    position of stock can be updated by computer. This operation of computer is intimately linked to

    other operations such as receipt of goods, dispensing of goods, billing of goods, returns of goods

    etc. For annual auditing of pharmacy department, records of numerous items are required to be

    typed laboriously. This can be overcome by use of computer through perpectual inventorycontrol and these records can be made ready for inspection at any time when needed. The

    computer can be effectively use whenever there are changes in the prices of items recorded. The

    patient billing is a time consuming but important activity for the hospital pharmacy and its

    accounting department. The pharmacy department must assure that all drugs leaving the

    pharmacy are billed to the appropriate patients account. The computer system automatically

    charges the patient all medications and IV solutions ordered.

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    For Formulary search and update the computers is capable of maintaining and displaying all

    drugs by descriptors code, therapeutic category or generic name.

    Computerization of narcotics and other controlled substances may help in preventing excessive

    supplies and unauthorized dispensing of such drugs. The specific identification codes are given

    to authorized person. The drug control authorities are directly linked through computers to such

    records. The program used for this purpose is DAWN (Drug Abuse Warning Network). (Yadav,

    2007)

    Therapeutic drug monitoring (TDM) aims to optimize treatments by individualizing dosage

    regimens based on the measurement of blood concentrations.(Fuchs A, 2013) Clinical

    pharmacist may use computers for therapeutic drug monitoring; which are very potent and

    having very narrow therapeutic range like cardiac glycosides, anticonvulsants. Computer

    program are designed to calculate drug dosage to suit individual patients need. (Shaha Y. I.,

    2008) Computer-assisted TDM is gaining growing interest and should further improve,

    especially in terms of information system interfacing, user friendliness, data storage capability

    and report generation.(Fuchs A, 2013) (David W. Bates, 1998)

    Computer Is also being effective for drug distribution. The computer system is believed to

    decrease the time spent by pharmacists on routine distribution tasks, leaving time for other

    necessary pharmacy functions. The system seems to improve pharmacy's efficiency, accuracy,

    control of drugs and capabilities for patient monitoring and drug use review. If mechanical

    failure occurs, back-up procedures keep the distribution system operational . (WL, 1978)Computer also implements its application in decentralized unit dose distribution system where

    using mobile pharmacy carts and computer terminals for filling inpatient and discharge

    medication orders are used . The system uses computer terminals mounted on mobile medication

    carts. Medication orders are collected from each nursing station by the pharmacist. Using the

    mobile combination decentralized medication cart/computer terminal (cart/CRT), the pharmacist

    examines and updates the patient's drug profile, checking for drug allergies and interactions, and

    bills the patient for drugs dispensed.Turnaround time for routine inpatient orders and discharge

    orders decreased substantially using this system, and the system was perceived as beneficial by

    nurses, physicians, and pharmacists. (Wareham DV, 1983)

    It is generally recognized that drug discovery and development are very time and resources

    consuming processes. Use of computational techniques in drug discovery and development

    process is rapidly gaining in popularity, implementation and appreciation. Commonly used

    computational approaches include ligand-based drug design (pharmacophore, a 3-D spatial

    arrangement of chemical features essential for biological activity), structure-based drug design.

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    (drug-target docking), and quantitative structure-activity and quantitative structure-property

    relationships. (Kapetanovic, 2008)

    Computer science and technology is deeply utilized in pharmacy field everywhere like in

    pharmacy colleges, pharmaceutical industries, research centers, hospital pharmacy and many

    more. Computer significantly reduces the time, expenditure, and manpower required for any kind

    of work. Development of various softwares makes it trouble-free to handle huge data. In short,

    computers are playing critical role in pharmacy field, without computers pharmacy research will

    be long-lasting and expensive.(Shivraj Popat Jadhav, 2010)

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    DISCUSSION AND CONCLUSION:

    Computers have played an important role in the development of clinical pharmacy practice and

    basic pharmacy research. The use of computer in hospital administration and medical research

    has become a need of todays hospitals. The computer is a processor which processes largequantity of data which may be letters, numbers, or picture elements very fastly and quickly. The

    decrease in cost of computers in recent times has allowed the pharmacists to increase the

    utilization of computers in clinical pharmacy practice.

    There are many uses of computers in pharmacies. They can help in

    Maintenance of records

    Distribution Of Drugs

    Drug Discovery

    Therapeutic Drug Monitoring

    Drug related problems

    Managing Controlled drug substances

    Maintaining Formulary

    Purchasing

    Inventory control

    Medication monitoring

    Drug information retrieval

    Storage and many more

    Computer systems in hospital pharmacy assure that patients coming in the pharmacy, their recorddatabase are continually updated to reflect the current status of them. The computer enables the

    pharmacist to gather other information such as present diagnosis, allergies, weight, height and

    any other special note about the patient. Computers also are very helpful in entering medication

    orders of the patient which directly ease out the pharmacists job and decrease the workload. The

    computers also aid in preparing labels as required. For this purpose different softwares and

    hardwares have been developed by the engineers that enable the pharmacist to find out the

    desired information in less than a fraction of a minute. A complete knowledge of drug

    information is necessary for the clinical pharmacist so as to satisfy the queries of the patient.

    This job can be simplified by the use of computers.

    Apart from information on retrieval, computers can also be utilized in other ways to obtain drug

    information in hospitals. Management information systems in the hospitals can be managed by

    computer. The information system has two main components:

    a) Information necessary for drug distribution

    b) Pharmacy management information

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    Another important application of computer in the relevant fields is in purchasing and inventory

    control. It helps to prepare a list of items to be purchased, prepares purchase orders for vendors

    and avoids duplicate orders and produce periodic summary and purchasing and inventory control

    statistics.

    Therapeutic drug monitoring is very important to maximize the therapeutic effect of the drug and

    to avoid any toxic effects especially in case of geriatric and pediatrics patients and for drugs

    having high tendency of drug interactions. The utility of computers in medication monitoring is

    of 2 types:

    1. Pharmacokinetic applications

    2. Non pharmacokinetic applications

    Pharmacokinetic applications include the estimation of pharmacokinetic parameters in

    individuals. The parameters commonly determined are rate of excretion, volume of distribution,

    clearance etc. whereas non pharmacokinetic application includes the drug-drug, drug allergy,drug-disease interaction detection. For interaction screening different computer programs have

    been developed such as MEDIPHOR (Monitoring and evaluation of drug interaction by a

    pharmacy oriented reporting) and PAD (Pharmacy automated drug interaction screening).

    Thus, using computers can enhance the standard of pharmacists clinical and hospital services.

    Computers gives faster, more accurate, more complete reporting with greater efficacy, their use

    in pharmacy is very beneficial. They have become indispensable in the development of clinical

    pharmacy, hospital pharmacy and pharmaceutical research. The use of computers has

    demonstrated the potential to decrease adverse events, preserve financial and medical resources,

    and improve patient management. As more hospitals move in the direction of computer accessmore clinical applications for computing programming have been identified. The computer is

    becoming the mainstay of hospital pharmacy practice. Enhancement of computer technology is

    essential to assist the hospital pharmacist in assimilating all relevant data in order to provide

    optimal oversight of drug therapy. As more data become available on drugs, optimal use of

    drugs, and factors which place the patient at risk for developing reactions to drugs, one must

    have to say that computer has become a necessary solution for optimizing patient care.

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    REFERENCES:

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