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Arthritis: An Overview Michael McKee, MD, MPH February 23, 2012

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Page 1: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Arthritis: An Overview

Michael McKee, MD, MPHFebruary 23, 2012

Page 2: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Supporters

Deaf Health Talks is possible through the support of: – Rochester Recreation Club for the Deaf

(“REAP”)– Deaf Health Community Committee

(DHCC)

Page 3: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Goals of Presentation

What is Arthritis?What are its symptoms?What causes Arthritis?How to diagnose Arthritis?What are treatments and drugs for Arthritis?Questions & Answers Time

Page 6: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

What are its symptoms?

Arthritis Symptoms– Joint pain– Joint stiffness– Joint swelling– Unable to move joint– Redness over joint

Page 7: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Where does arthritis happen?

Can happen in any jointMost common sites: – Knees– Hips– Back– Ankles– Shoulders– Hands and fingers

Page 8: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

What causes arthritis?

Common Causes:– Osteoarthritis– Autoimmune

Rheumatoid arthritisLupus

– Gout

Page 10: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Osteoarthritis

Joints get worn out (degenerative joint disease)– Risk factors:

Obesity/heavy weightInjuries to joints (sports injuries, car crashes)InfectionsOld age

Page 11: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Autoimmune (Rheumatoid Arthritis)

In rheumatoid arthritis, the body's immune system attacks joints and synoviumThe disease can eventually destroy cartilage and bone within the joint.Risk Factors

– Women>Men– Family History– Young (25-50 years old)

http://www.cedars-sinai.edu/Patients/Health-Conditions/Arthritis---Rheumatoid-Arthritis-Osteoarthritis-and-Spinal-Arthritis.aspx

Page 12: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Rheumatoid Arthritis (cont)

Joint pains tend to be on both sides– Stiffness tend to not go away quickly after waking

up- 1-2 hours longCommon sites: hands, feet, wrists, elbows and anklesOther symptoms: fever, feeling tiredCan affect the heart and lungs

http://www.cedars-sinai.edu/Patients/Health-Conditions/Arthritis---Rheumatoid-Arthritis-Osteoarthritis-and-Spinal-Arthritis.aspx

Page 13: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Rheumatoid Arthritis (cont)

Most people will need special medication treatments– Medications are to reduce immune response

that causes damage to body– Treat pain– Medications require monitoring due to side

effectsCan harm liver and blood cellsCan increase risk for infections

Rheumatologist (joint doctors)http://www.cedars-sinai.edu/Patients/Health-Conditions/Arthritis---Rheumatoid-Arthritis-Osteoarthritis-and-Spinal-Arthritis.aspx

Page 14: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Lupus

Inflammatory arthritis due to autoimmune disorderAffects many parts of the body- not just the joints– Can damage the lungs, kidneys, heart

More common in:– Women– African-Americans– Pregnancy

Page 15: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Lupus

Symptoms are many:– Rashes: butterfly-shaped rash across the bridge of the nose

and cheeks– Sensitivity to sunlight– Skin ulcers– Arthritis – Kidney problems

Treatments vary but try to reducesymptoms and immune response

http://www.cedars-sinai.edu/Patients/Health-Conditions/Lupus.aspx

Page 16: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Gout

Caused by deposits of uric acid– Uric acid causes

damage to joints– Very painful!!– Risk factors:

High uric acid dietMen

Photo 1: arthritishubs.com; Photo 2:arthritisdiseasefacts.com

Page 17: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Gout

If you have gout, you should eat a low purine diet which helps

– Limit meat, poultry and fish. Animal proteins are high in purine.

Limit your intake to 4 to 6 ounces

– Eat more plant-based proteins. You can increase your protein by including more plant-based sources, such as beans and legumes.

– Limit or avoid alcohol. Alcohol interferes with the elimination of uric acid from your body.

Beer appears to be the worst!

http://www.mayoclinic.com/health/gout-diet/MY01137

Page 18: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Choose low-fat or fat-free dairy products– Eating this may help reduce risk of gout Eat more complex carbohydrates (whole grains, fruits and vegetables). – Avoid “white foods”- white bread, sugar, white

flourKey is to drink plenty of fluids and to lose weight if you are heavy!

Gout (cont)

http://www.mayoclinic.com/health/gout-diet/MY01137

Page 19: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Treatments for Arthritis

Joint injections (“cortisone shots”)Physical therapyWeight lossExerciseMedications

Page 20: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Joint Injections (Knee)

Photo: http://www.sciencephoto.com/media/200522/enlarge

•Injections use medications that reduce pain and inflammation

•Corticosteroid•Lidocaine

•Same approach can be used to drain knee

Page 21: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Arthritis Medications

Non-steroidal– Alleve (naproxen)- max 1,000 to 1,500 mg daily– Advil (ibuprofen)- max 1800 to 2400 mg daily– Aspirin (many take this for heart protection)

Max is 4,000 mg daily but avoid high doseCaution- these medications can increase risk for the following:– Stomach bleeds– High blood pressure– Talk with your doctor if you have heart or bleeding

issues

Page 22: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Arthritis Medications

Tylenol (acetaminophen)– Caution with taking too much which can damage

your liver– Recommended dose is no more than 2,400-3,000

mg daily– Tablets come in different sizes (325 mg, 500 mg,

650 mg)

Presenter
Presentation Notes
MedicationsThe medications used to treat arthritis vary, depending on the type of arthritis. Commonly used arthritis medications include:Analgesics. These types of medications help reduce pain, but have no effect on inflammation. Examples include acetaminophen (Tylenol, others), tramadol (Ultram, Ryzolt) and narcotics containing oxycodone (Percocet, Oxycontin, others) or hydrocodone (Vicodin, Lortab, others).Nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs reduce both pain and inflammation. Over-the-counter NSAIDs include ibuprofen (Advil, Motrin, others) and naproxen (Aleve). Some types of NSAIDs are available only by prescription. Oral NSAIDs can cause stomach irritation, and some may increase your risk of heart attack or stroke. Some NSAIDs are also available as creams or gels, which can be rubbed on joints.Counterirritants. Some varieties of creams and ointments contain menthol or capsaicin, the ingredient that makes hot peppers spicy. Rubbing these preparations on the skin over your aching joint may interfere with the transmission of pain signals from the joint itself.Disease-modifying antirheumatic drugs (DMARDs). Often used to treat rheumatoid arthritis, DMARDs slow or stop your immune system from attacking your joints. Examples include methotrexate (Trexall) and hydroxychloroquine (Plaquenil).Biologics. Typically used in conjunction with DMARDs, biologic response modifiers are genetically engineered drugs that target various protein molecules that are involved in the immune response. Examples include etanercept (Enbrel) and infliximab (Remicade).Corticosteroids. This class of drug, which includes prednisone and cortisone, reduces inflammation and suppresses the immune system. Corticosteroids can be taken orally or be injected directly into the painful joint.TherapyPhysical therapy can be helpful for some types of arthritis. Exercises can improve range of motion and strengthen the muscles surrounding joints. In some cases, splints or braces may be warranted.SurgeryIf conservative measures don't help, your doctor may suggest surgery, such as:Joint replacement. This procedure removes your damaged joint and replaces it with an artificial one. Joints most commonly replaced are hips and knees.Joint fusion. This procedure is more often used for smaller joints, such as those in the wrist, ankle and fingers. It removes the ends of the two bones in the joint and then locks those ends together until they heal into one rigid unit.
Page 23: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Arthritis Medications

Non-steroidal– Alleve (naproxen)– Advil (ibuprofen)– Aspirin

Caution- these medications can increase risk for the following:Stomach bleedsHigh blood pressure

Presenter
Presentation Notes
MedicationsThe medications used to treat arthritis vary, depending on the type of arthritis. Commonly used arthritis medications include:Analgesics. These types of medications help reduce pain, but have no effect on inflammation. Examples include acetaminophen (Tylenol, others), tramadol (Ultram, Ryzolt) and narcotics containing oxycodone (Percocet, Oxycontin, others) or hydrocodone (Vicodin, Lortab, others).Nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs reduce both pain and inflammation. Over-the-counter NSAIDs include ibuprofen (Advil, Motrin, others) and naproxen (Aleve). Some types of NSAIDs are available only by prescription. Oral NSAIDs can cause stomach irritation, and some may increase your risk of heart attack or stroke. Some NSAIDs are also available as creams or gels, which can be rubbed on joints.Counterirritants. Some varieties of creams and ointments contain menthol or capsaicin, the ingredient that makes hot peppers spicy. Rubbing these preparations on the skin over your aching joint may interfere with the transmission of pain signals from the joint itself.Disease-modifying antirheumatic drugs (DMARDs). Often used to treat rheumatoid arthritis, DMARDs slow or stop your immune system from attacking your joints. Examples include methotrexate (Trexall) and hydroxychloroquine (Plaquenil).Biologics. Typically used in conjunction with DMARDs, biologic response modifiers are genetically engineered drugs that target various protein molecules that are involved in the immune response. Examples include etanercept (Enbrel) and infliximab (Remicade).Corticosteroids. This class of drug, which includes prednisone and cortisone, reduces inflammation and suppresses the immune system. Corticosteroids can be taken orally or be injected directly into the painful joint.TherapyPhysical therapy can be helpful for some types of arthritis. Exercises can improve range of motion and strengthen the muscles surrounding joints. In some cases, splints or braces may be warranted.SurgeryIf conservative measures don't help, your doctor may suggest surgery, such as:Joint replacement. This procedure removes your damaged joint and replaces it with an artificial one. Joints most commonly replaced are hips and knees.Joint fusion. This procedure is more often used for smaller joints, such as those in the wrist, ankle and fingers. It removes the ends of the two bones in the joint and then locks those ends together until they heal into one rigid unit.
Page 24: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Alternative Treatments

Glucosamine Chrondoitin Sulfate- 1,500 mg daily– Slow acting- need to try for 3 months to see if

works but very safeYoga or Tai Chi– Can strengthen joints and reduce pain

Acupuncture may also helpOmega-3 fatty acids (fish oil)- may help

Page 25: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Tests

Laboratory testsBlood: Can be done to check for autoimmune (rheumatoid or lupus)Xrays: Can check to see how severe the joint appearsJoint Fluid: Helps to check to see which type of arthritis you have (only can be done if have swelling)

Page 26: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Tests

MRI: Checks ligament and cartilage damage– very expensive- must be a good reason before

orderingArthroscopy: Done by orthopedics- insert a small tube and camera into the joint to see what the joint looks like

Page 28: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Other Arthritis Issues

Thumb Joint (“Blackberry thumb”)– Over time, can cause arthritis from heavy use of

pagers and smartphonesNot all arthritis is due to the joint– Tendonitis– Muscle tears/strains– Infection– Injuries and Bruising

Page 29: Arthritis: An Overview - Rochester, NY · PDF fileWhat is Arthritis? z What are its symptoms? z What causes Arthritis? z How to diagnose Arthritis? z ... If you have gout, you should

Questions???

Thank you!

Next Deaf Health Talk on March 15- “Dental Health” by our very own Deaf Dentist, Christopher Lehfeldt!