asean gmf net
TRANSCRIPT
Dr Zamri Ishak Elliza Mat Nor
SEMINAR KESEDARAN GMO KEBANGSAAN
01-02hb Nov 2016Hotel Armada Petaling Jaya 1
ROLES OF
JABATAN KIMIA MALAYSIA
National
• GMO Laboratory –The
only lab to support
enforcement of Biosafety
Act 2007 and release
reports for export
certificates, Food Act
1985
• National Reference
Laboratory for GMO
• Lead agency of GMO
Technical Working Group
• Member of Malaysian
Genetic Modification
Advisory Committee
(GMAC)
International
• ASEAN Food Testing
Laboratories Committee (AFTLC)
• ASEAN Genetically Modified
Food Network (GMFNet) with
MARDI
• ASEAN Reference Laboratory
For GMO (since 2004)
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ON-GOING MAIN TECHNICAL
ACTIVITIES IN JABATAN KIMIA
MALAYSIA
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• Method expansion, validation &
accreditation under ISO 17025
• Proficiency Testing Provider for GMO
• Training Provider
• Coordinating GMO activities in Malaysia
and ASEAN
Scope of GMO testing
-Raw and processed food
-Qualitative and quantitative detection by
PCR , Real-time PCR and
Digital Droplet -PCR
-Crop: Soybean, Maize, Rice, Papaya,
Potato, wheat, and other crops
GMO Analyses:
>90 accredited Methods (ISO
17025)
SAMPLE DNA EXTRACTION
POSITIVE
GM IDENTIFICATION
GM SCREENING
GM QUANTIFICATION
GMO Detection in Malaysia
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DNA technique:
• DNA Extraction – e.g. Wizard, MagNa Pure,
Qiagen
• GMO screening using DNA (e.g. to detect
common targets such as 35S) & protein
techniques (dipstick)
• GMO Identification – using conventional PCR and
real-time PCR technique, e.g. Roundup Ready
Soya
• GMO Quantification – using TaqMan chemistry to
express % GMO
ISSUES & CHALLENGES IN
MALAYSIA
TECHNICAL
• Selectable marker>50
types
• Gene of interest
• Marker free GM
varieties
• Stacked events
FINANCIAL
• Instruments
• Consumables
• Reagents
• Certified Reference
Materials
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New area of testing
- Unavailability of certain reference materials
- Sequences not disclosed
- Gene stacks in GMO are very difficult to analyze (have to test each grain, currently not possible to analyze processed food products)
- Only few methods have been “fully validated’, but the number is slowly increasing
- Highly processed foods –problem 8
- Unavailability of certain reference
materials, GMO detection limited to
available protocol and certified reference
material
- related to religious issues e.g detection
of swine gene in food
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How to overcome
• Blue Ocean Strategy
oNo redundancy
o Sharing outsources
o Knowledge transfer
• New Initiative for 2017
oMyGMO@kimia as one-stop-
centre for NRL management and
monitoring
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GMO RESEARCH IN MALAYSIA
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•GMO research is actively being done
at public and private research
institutes & universities
•GMO research is ongoing for food
products as well as non food
organisms (virus, bacteria, zebrafish,
mosquitoes, algae, yeast etc.)
GMO ANALYSIS AT
ASEAN LEVEL(ASEAN GMF Net)
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The main objectives of ASEAN GMF-Net are
as follows:
1.To ensure harmonization in detection of GMF
and improve competencies among scientists
and regulators in AMSs.
2.To provide sharing of knowledge and
experiences in the implementation of relevant
legislations pertaining to GMFs at the regional
level.
3.To provide training in detection of GMF for all
AMSs.
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Justification
ASEAN Genetically Modified Food Testing Network (ASEAN GMF Net) is an important platform to promote ASEAN cooperation in GM technology particularly in the area of GMO testing.
Since the number of new GM crops imported into the ASEAN GMF Net countries has increased dramatically, the ASEAN cooperation on GMO testing need to be further strengthened at the regional level.
All ASEAN Member Countries (AMCs) has to leverage on each other’s resources, knowledge and expertise in GM technology to promote food safety in the region.
This ASEAN GMF net was established in 2006 14
Most of the AMCs (ASEAN Member Countries) have established or are in the process of formulating their own Biosafety Laws to control importation, release and exportation of GMO and products thereof.
Malaysia has gazetted its Biosafety Act since August 2007. Therefore, there is a vital need to test the presence of GMO in shipments in order to ensure compliance with regulatory requirements of these AMCs and importing countries.
Recently Malaysia also has gazetted its labelling act for GM Food product since 2014.
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In 2016-2020, ASEAN GMF Net will focus on the following activities:
(i) Drafting of Harmonized Regulatory Framework for GM Food;
(ii) Drafting of Harmonized GMO Detection Approach and Methodology;
(iii) Updating the information on modern biotechnology development and its impact on agriculture, food and forestry products and
(iv) Continue to enhance AMS’s GMO testing capabilities through training and collaboration within ASEAN and with other international or regional organizations
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Overview EU-ASEAN Cooperation on GMO Analysis
Summary
Formalization of the EU-ASEAN Cooperation in GMO Analysis
Future Regional Network Meeting
International Workshop on GMO Analysis Networking
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Formalization of the EU-ASEAN
Cooperation in GMO Analysis
Dec. 6th 2012, ASEC proposed mechanism for
the Formalization of the EU-ASEAN Technical
Cooperation on GMO Analysis i.e. through
Exchange of Letters.
Singapore has been following up with EU on this
matter
8th ASEAN GMFT Net MeetingSingapore, June 9-10, 2011
EC-JRC Proposal
-Networking, -Proficiency Testing,
-Plasmid Control Samples, -Global GMO Matrix
-formalization through collaboration MoU
Broadening collaboration
Broadening collaboration
The 8th ASEAN GMFT Net meeting -Endorsed the ASEAN-EU cooperation on
technical GMO analysis,-Agreed to formalise this Technical
Cooperation with EU.
Oct. 4th 2011, Jakarta, SOM* – 33rd AMAFMeeting
-Support the technical cooperation-Requested the ASEAN GMF Net to explore
mechanisms for the expedient conclusion of a formal collaborative
*Senior Officials Meeting of the ASEAN Ministers on Agriculture and Forestry
Formalization of the EU-ASEAN
Cooperation in GMO Analysis
Indication from EC side to Singapore / ASEAN GMFTNet:
For ASEAN GMF Network to consider which level of representation is
proposed by ASEC for the exchange of letters ?
Request for ASEC to provide more information on how to proceed ?
EC also proposed a new option of a horizontal
"scientific and technical cooperation" document between
JRC and ASEAN, in which GMO analysis will be highlighted as
one specific area for cooperation
For ASEAN to consider whether this is feasible and what other areas
besides GMO analysis will be included?
Or ASEAN to prefer to focus on GMO Analysis for specific cooperation?
Request ASEAN to make a proposal to EC. To also include as part of the
Proposal the expected timelines
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Challenges in ASEAN for GMO Analysis
Lab capabilities is not at the same level
(Brunei, Mymar and Laos DPR has no proper lab for GMO analysis) Funding is limited in certain ASEAN country New GM crops imported into the ASEAN GMF Net countries has increased dramatically Lack of Public and Government awareness Harmonization in ASEAN country is not fully taking place yetInternational Networking is necessary
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