Name: ______________________________ Section:__________________ Date: ___________

Asexual Reproduction Worksheet: Mitosis and Cytokinesis (50pts)Instructions: Fill in the blanks with the correct terms. If a number is repeated, that means that the missing word is the same word as all the other blanks with the same number.

After going through Interphase, the cell goes into (1) _________________ phase and then (2) _______________. Mitosis is the division of the (3) _______________, and cytokinesis is the division of the (4) __________________.

The first stage of mitosis is (5) __________________. Several important things happen in this stage. The chromatin (6) _____________ to form chromosomes. This is down by wrapping around (7) ______________________ and by the use of a protein called (8) _________________. Also essential to holding chromosomes together is (9) ___________, which is responsible for holding sister chromatids together. The formation of (10) ______________________ from the disassembly of the cytoskeleton also occurs within this phase.

The second stage of mitosis is (11) ____________________, but is sometimes included within prophase. In this phase, spindle fibers attach to chromosomes at the (12) _________________, which are located on the chromosome's (13) __________________. Then, the spindle fibers start pulling chromosomes back in forth toward the center of the cell in a process known as (14) ________________. This process is not totally completed until (15) __________________, at which point the chromosomes are aligned on the cellular equator, called the (16) _____________________. If the chromosomes are not properly aligned, (17) _________________ can occur, which is when a cell has an abnormal amount of chromosomes. The protein essential in preventing this is (18) _______.

The fourth stage of mitosis is (19) _________________. This cannot happen without (20) _____________, an enzyme that denatures cohesin. With cohesin destroyed, spindle microtubules attach to the kinetochores and pull the sister chromatids towards (21) _______________________. This process is more specifically referred to as (22) ______________________. Unattached microtubules press against each other and push the poles further away, which is described as (23) ________________________.

The last stage of mitosis is (24) _____________, in which the mitotic spindles disassemble, chromosomes decondense, and the daughter cells return to interphase condition.

After M phase, the cell enters (25) __________________, which is the partitioning of the cell cytoplasm. The process in animal cells is performed by a (26) ________________,

which is composed of (27) ________ and ___________ filaments. The protein responsible for the assembly of the filaments is (28) ________. In plant cells, cytokinesis is different. A new cell wall is formed from Golgi-derived carbohydrate vesicles that fuse at the (29) ________________. The carbohydrate vesicles are guided there by (30) _____________________.

Instructions: Match the following definitions/descriptions to its correct term. For these purposes, incorporate prometaphase into prophase.

31. ____ chromosomes move towards the poles of the spindle32. ____ chromosomes finish migration to the cell's equator33. ____ replicated chromosomes coil up and condense34. ____ the centromeres divide into two35. ____ the mitotic spindle breaks down36. ____ the nuclear envelope disintegrates37. ____ chromosomes decondense38. ____ the mitotic spindle forms

39. ____ often overlaps with cytokinesisa. prophaseb. metaphasec. anaphased. telophase

Instructions: Label the following cell cycle diagram. On the side, briefly highlight the key events of each stage of mitosis. (6pts)