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Page 1: athfinder England - Target Ovarian Cancer...10 Pathfinder England – transforming futures for women with ovarian cancer Clinical trials offer women the opportunity to access new cancer

Transforming futures for women with ovarian cancer

Pathfinder England

Page 2: athfinder England - Target Ovarian Cancer...10 Pathfinder England – transforming futures for women with ovarian cancer Clinical trials offer women the opportunity to access new cancer

2 Pathfinder England – transforming futures for women with ovarian cancer

43% of women visit their GP

three times or more before being referred for diagnostic tests

66% of women with ovarian cancer are prepared to travel to take

part in clinical trials

21% of women able to name

bloating as a symptom of ovarian cancer

45% of GPs wrongly believe

symptoms only present in the later stages of the disease

78% of women with ovarian cancer

experience mental ill health

of women incorrectly believe

cervical screening also detects ovarian cancer

30%

Pathfinder England at a glance

of women with ovarian cancer are given written information at the

point of diagnosis64%

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Contents

Pathfinder England at a glance 2

Introduction 4

Awareness of symptoms 6

Diagnosis 7

Genetics 8

Starting treatment 9

Clinical trials 10

Support 11

Mental wellbeing and body image 11

Recurrence 11

Conclusions 12

Thank you 16

The Pathfinder Advisory Panel 16

Methodology 17

References 19

Pathfinder England – transforming futures for women with ovarian cancer 3

Target Ovarian Cancer works to improve early diagnosis, fund life saving research and provide much needed support to women with ovarian cancer.

We are the authority on ovarian cancer. We work with women, family members and health professionals to ensure we target the areas that matter most for those living and working with ovarian cancer.

In Engand we:

• hold Being Together support days for women with ovarian cancer.

• invest in research.

• distribute our guides and information to cancer centres across England.

• promote our free GP toolkit to improve early diagnosis.

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Over 6,000 women are diagnosed with ovarian cancer in England every year.1 In recent years there have been increasing efforts to drive forward early diagnosis and ensure more women with ovarian cancer survive the disease:

• Thefirstgovernmentfundedovariancancerawarenesscampaigntookplacein2013withalocalBeClearonCancerpilot.Thiswasfollowedbyaregionalcampaignin2014.Afurtherregionalpilot,takinganewapproachgroupingsymptomsbybodysite,ratherthantypeofcancer,ranin2017andfeaturedbloatingasakeysymptom.2,3

• In2013theNationalInstituteforHealthandCareExcellencerecommendedallwomenwithnon-mucinousepithelialovariancancerbeofferedgenetictestingfortheBRCAgeneandin2015thiswasincorporatedintoNHSEnglandcommissioningguidelines.4,5

• In2011bevacizumab(Avastin©)becameavailablethroughtheCancerDrugsFundforthefirstlinetreatmentofsomewomenwithadvancedovariancancerandin2016olaparib(Lynparza©)wasapprovedbytheNationalInstituteforHealthandCareExcellenceasmaintenancetreatmentforrelapsedBRCA-mutated,platinumsensitiveovariancancerinwomenwhohavehadthreeormorecoursesofchemotherapy.6,7

However,whilesurvivalrateshaveimprovedinrecentyears,theystilllagbehindthoseforothercancersandnearly3,500womendieofthediseaseinEnglandeveryyear.8

ItisclearmoreneedstobedoneandthisisthereforeacriticaltimetobepublishingthefirstPathfinderEngland,lookingatwomen’sawarenessofovariancancer,theirexperienceofdiagnosisandtreatmentandGPknowledge.

PathfinderEnglandisbasedonthreedifferentsurveys:

• Womeninthegeneralpopulation

• Womenwithovariancancer

• PractisingGPs

Thereportisstructuredaroundthepatientpathway.Itbeginswithawarenessanddiagnosis,beforemovingontotreatmentandsupport.Italsohassectionslookingatgenetics,clinicaltrialsandmentalwellbeingandbodyimagetopresentamorecompletepicture.

Whilerecognisingtheworkthathasbeendonealreadytoimprovethediagnosisandtreatmentofovariancancer,PathfinderEnglandsetsoutwhatneedstohappennexttotransformoutcomesforwomenlivingwithovariancancerinEnglandtoday,andthosediagnosedtomorrow.

Introduction

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Pathfinder England – transforming futures for women with ovarian cancer 5

The top three actions identified by Pathfinder England are:

• A national Be Clear on Cancer campaign that includes the symptoms of ovarian cancer so women know the symptoms to look out for and the importance of going to the GP.

• NHS England to ensure all women with ovarian cancer are aware of where to go for support, including counselling.

• An ovarian cancer audit in England mapping and evaluating the diagnostic and treatment pathway for all women with ovarian cancer.

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By knowing the symptoms to look out for, women are more likely to visit their GP sooner, increasing their chances of being diagnosed earlier.

ThekeysymptomsofovariancancerassetoutinNationalInstituteforHealthandCareExcellence(NICE)guidelinesare:

• Persistentabdominaldistension(bloatedtummy)

• Pelvicorabdominalpain(tummypain)

• Feelingfull(earlysatiety)and/orlossofappetite(alwaysfeelingfull)

• Increasedurinaryurgencyand/orfrequency(needingtoweemore)

Symptomscanalsoinclude:

• Unexplainedweightloss

• Unexplainedfatigue

• Unexplainedchangesinbowelhabit9

Womeninthegeneralpopulationwereaskedtosaywhichsymptomstheythinkmightbelinkedtoovariancancer.

Thereisalsowidespreadconfusionwithcervicalcancer,with30percentofwomeninEnglandincorrectlybelievingthatcervicalscreeningalsodetectsovariancancer.

Makingsurewomenknowthesymptomstolookoutforisthefirststepinensuringmorewomenarediagnosedsooner,yetatthemomenttoofewwomeninEnglandknowthewarningsigns.

Table 1. Ability of women in the general population to name one of the four main symptoms of ovarian cancer (unprompted)

Persistentbloating(percent) 21

Pelvicorabdominalpain(percent) 20

Feelingfull/lossofappetite(percent) 3

Increasedurinaryurgency/frequency(percent) 1

Awareness of symptoms

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Numbers do not total 100 due to a small number of patients unsure of the time taken to receive a diagnosis.

Diagnosis

Table 2. GP beliefs regarding presentation of symptoms of ovarian cancer

GPssayingsymptomsonlypresentinthelaterstagesofthedisease(percent)

45

GPssayingovariancancerisasilentkiller(percent) 76

Table 3. Time taken from first visiting GP to receiving diagnosis

Lessthanonemonth(percent) 27

Onetothreemonths(percent) 29

Overthreemonths(percent) 43

NICE guidelines set out how GPs should assess and refer women with symptoms that could be ovarian cancer.

GPsshouldstartbydiscussingthesymptomsexperiencedbywomenandtheirfrequencybeforecarryingoutapelvicexaminationtocheckforamassorascites(fluidintheabdomen).Ifamassorascitesarefound,GPsshouldmakeanurgentreferraltoagynaecologicaloncologist.

InallothercasesGPsshouldreferwomenforaCA125bloodtest.IfthisshowsraisedlevelsoftheCA125protein,thenwomenshouldbereferredforanultrasound(transvaginalandabdominal).

InthepastmanyGPshaveheldmistakenbeliefsaroundthediagnosisofovariancancerandTable2showsthatthesepersisttoday,withmanyGPsinEnglandwronglybelievingthatovariancancercannotbepickedupearlyordoesnothaverecognisablesymptoms.Thisisdespiteclearclinicalguidelinestothecontrary.

43percentofwomensubsequentlydiagnosedwithovariancancervisitedtheirGPthreetimesormorebeforebeingreferredfordiagnostictestsand46percentofwomenwereinitiallyreferredfortestsforsomethingotherthanovariancancer.Table3showsthat72percentofwomenarewaitingonemonthormoreforadiagnosisaftertheirfirstvisittotheGP.

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There are several genetic faults or mutations linked to ovarian cancer. Of greatest significance is a mutation in the BRCA1 or BRCA2 gene; this mutation accounts for around 13 per cent of all cases of ovarian cancer.10 The risk of developing ovarian cancer is two per cent for women generally, but rises to 30-50 per cent for women with a BRCA1 mutation and 10-25 per cent for women with a BRCA2 mutation.11 BRCA mutations can pass down either the mother’s or father’s side of the family. If a parent has the BRCA mutation, there is a 50 per cent chance that they pass it on to their child.

Despitethis,thereislowawarenessofthesignificanceofgeneticsinrelationtoovariancancer.AmongwomeninthegeneralpopulationinEngland,only26percentthinkgeneticsmightbeafactorindevelopingovariancancerwhile45percentofwomenwithovariancancerinEnglandareawaretheremightbeageneticlink.

AmongGPs,thereishighawareness(93percent)oftheimportanceoffamilyhistoryonthemother’sside,butmuchlowerawarenessoftheimportanceoffamilyhistoryonthefather’sside,withjust38percentsayingthismattered.

Genetics

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Starting treatment

Women diagnosed with ovarian cancer are offered a combination of surgery and chemotherapy, or, in a very few cases, surgery or chemotherapy alone.

Guidelinesrequireallwomendiagnosedwithovariancancertobeofferedinformation,includingwritteninformation,abouttreatment.12Tables4and5showthatwomeninEnglandarereceivingexcellentcareandattentionfrommedicalstaffwhenitcomestoexplainingtheirdiagnosisandtreatment,butalsoshowthatasignificantnumberofwomenarenotreceivingwritteninformationinadditiontoaverbalexplanation.

Giventhevolumeofinformationpatientsareoftenfacedwithhavingtotakeinatachallengingtime,writteninformationisimportantinprovidingthemwithsomethingtheycanreferbackto.

Diagnosis Surgery Chemotherapy

Diagnosis Chemotherapy Surgery Chemotherapy

Diagnosis Chemotherapy

Diagnosis Surgery

Table 4. Women reporting their diagnosis and treatment was explained to them in a way they could understand

Diagnosisexplainedinawaywomencouldunderstand(percent) 81

Surgeryexplainedinawaywomencouldunderstand(percent) 92

Chemotherapyexplainedinawaywomencouldunderstand(percent) 95

Table 5. Women reporting they were provided with written information at diagnosis and during treatment

Writteninformationatpointofdiagnosis(percent) 64

Writteninformationbeforesurgery(percent) 72

Writteninformationbeforechemotherapy(percent) 95

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Clinical trials offer women the opportunity to access new cancer drugs, improve understanding of the disease and treatment options, and access the highest quality care. Research shows that those taking part in clinical trials have improved survival rates, regardless of whether they receive the new treatment or the standard treatment.13

InEngland,35percentofwomenwithovariancancerhadbeenaskediftheywouldliketotakepartinaclinicaltrialand28percenthadjoinedatrial.Findingsalsoshowedthatthemajorityofwomen(66percent)werepreparedtotraveltoanotherhospitalinordertotakepartinaclinicaltrial.

ThisbroadlycorrespondstotheNationalCancerPatientExperienceSurvey,where38percentofwomenwithovariancancerreportedthatsomeonehaddiscussedtakingpartincancerresearch.14

Clinical trials

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Support

Clinical Nurse Specialists (CNSs) are there to act as the main contact point for women with ovarian cancer, oversee their general care and offer advice and support. 92 per cent of women with ovarian cancer in England reported having access to a CNS.

Recurrence

Mental wellbeing & body image

Aside from the physical implications of a diagnosis of ovarian cancer, having cancer and the treatment involved can impact on a woman’s mental wellbeing and affect her body image and confidence.

Mental wellbeing78percentofwomenwithovariancancerlivinginEnglandreporthavingexperiencedmentalillhealth(includingdepression,anxiety,stress,lowmoodandmoodswings)sincebeingdiagnosedwithovariancancer.Incontrast,just33percentofwomensaidanyoneinvolvedintheirtreatmenthaddiscussedtheirmentalwellbeingwiththem.

Body image and sexualityManywomenstrugglewiththeirbodyimageposttreatmentandwithregainingsexualintimacy.67percentofwomenwithovariancancerinEnglandsaidtheyhadexperiencedalossofselfesteem,68percentofwomenreporteddifficultieswithintimacyand78percentreportedalowersexdrive.

Many women are not having possible symptoms of recurrent ovarian cancer discussed with them after completing treatment. 53 per cent of women with ovarian cancer living in England said no one talked them through the symptoms of recurrent ovarian cancer. At the same time, 49 per cent of women said they needed support coping with the fear of recurrence.

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Action Target Ovarian Cancer to double the number of GPs who have completed accredited training on ovarian cancer.

Action Following the pilots, multi-disciplinary diagnostic centres to be rolled out at the earliest opportunity and to include ovarian cancer.

The findings in the preceding pages show what is working when it comes to diagnosing and treating ovarian cancer in England, but they also show where more remains to be done, including in the following areas:

AwarenessThefirststepinensuringmorewomenarediagnosedearlierandhavethebestpossiblechanceofsurvivalismakingsuretheyknowthesymptomstolookoutforandtheimportanceofactingonthese.

ThegovernmentfundedBeClearonCancercampaignsaimtoimprovecancersurvivalthroughraisingawarenessofthesymptomsofcancerandencouragingpeopletovisittheirGPsooner.WhilelocalandregionalpilotshavefeaturedovariancancersymptomstherehasyettobeanEnglandwidecampaign.

DiagnosisWomeninEnglandaremakingmultiplevisitstotheirGPbeforebeingreferredfordiagnostictests.

Newmulti-disciplinarydiagnosticcentres,currentlybeingpilotedatmultiplesitesacrossEngland,offerareferralpathwayforvaguesymptomsandhavethepotentialtospeedupdiagnosis.15

Conclusions

Action A national Be Clear on Cancer campaign that includes the symptoms of ovarian cancer so women know the symptoms to look out for and the importance of going to the GP.

GeneticsBothamongthegeneralpopulationandwomenwithovariancancer,awarenessofthesignificanceofgeneticsandfamilyhistoryremainslow.WhileGPsappreciatethe

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importanceoffamilyhistoryonthemother’sside,farfewerareawareoftheequalrelevanceoffamilyhistoryonthefather’sside.

TreatmentWomen’sfeedbackonthewaytheirdiagnosisandtreatmentisexplainedtothemisextremelypromising,showingthatthemajorityofwomenarehavingtheirtreatmentexplainedtotheminaclearandaccessiblemanner.

Womenarepresentedwithahugeamountofinformation,bothatdiagnosisandthroughouttreatment,andwritteninformationisvitalinensuringwomencanaccesstheinformationtheyneedwhentheyneedit.

Clinical trialsClinicaltrialsarediscussedwithonlyaminorityofpatients.Thismightberelatedtoclinicians’concernsaboutthesuitabilityoftrials,thedistancesinvolvedortheavailabilityoftrialsatthatpointintime.

However,manywomenarepreparedtotraveltoaccessthelatesttrialsanditisimportant

Action NHS England to ensure all women are provided with written information at the point of diagnosis and at other significant milestones in their care and treatment.

Action Target Ovarian Cancer to develop personalised information for women with ovarian cancer reflecting the type of cancer and the stage they are at in their treatment.

Action Target Ovarian Cancer to distribute their free guide on genetic testing to all cancer centres in England.

Action Target Ovarian Cancer to promote information and training for GPs stressing the importance of family history on both sides.

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thatallwomenareawareoftheopportunitiesofferedbytakingpartinclinicaltrials.Insomecasesitmaybethattherearenosuitabletrials,butdiscussingthiswithapersonhelpsthemunderstandthesituationandbebetterinformedabouttheoptionsavailabletothem.

Action NHS England to ensure all women with ovarian cancer are given information on clinical trials and how to access them.

Action NHS England to ensure all women with ovarian cancer are aware of where to go for support, including counselling.

Action NHS England to ensure all women with ovarian cancer have the symptoms of recurrent disease discussed with them following treatment.

Support coping with fears of recurrenceOverhalfofwomensaytheyneedsupportcopingwiththefearofthediseasereturning.Thefirststepinmeetingthisisensuringthateverywomanistoldthesymptomstolookoutforandwhattodoifsheisworriedthattheovariancancermayhavereturned.

Action Target Ovarian Cancer to continue to provide patient facing information on clinical trials through its Ovarian Cancer Clinical Trials Information Centre.

Mental wellbeing and body imageBeingdiagnosedwithandtreatedforovariancancerdoesnotjustplaceaphysicalstrainonwomen,butamentalstraintoo.PathfinderEnglandshowsahighlevelofunmetneedamongwomenwithovariancancerinrelationtotheirmentalwellbeing.

Alargenumberofwomenwithovariancanceralsoreportdifficultieswithbodyimageandregainingsexualintimacyfollowingtreatment.

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Action Target Ovarian Cancer to invest in new services and support to help meet the wider needs, including mental health and sexuality, of women with ovarian cancer.

Action An ovarian cancer audit in England mapping and evaluating the diagnostic and treatment pathway for all women with ovarian cancer.

Measuring progressTodevelopoursharedunderstandingofthediagnosticandtreatmentpathwayforovariancancer,andbetterpinpointwherechangeisneeded,anovariancancerauditiscalledfor.ThisbuildsontherecommendationsoftheChiefMedicalOfficerwhocalledfortheinclusionofanovariancancerauditinNHSEngland’sNationalClinicalAuditandPatientOutcomesProgramme.16

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TargetOvarianCancerwouldliketothankthePeterSowerbyFoundationwhosekindgenerositymadethisresearchpossible.

WewouldalsoliketothankallthosewhotookthetimetocompletethesurveysthatmakeupPathfinder;wecouldnothavedoneitwithoutyou.

The Pathfinder Advisory PanelParticularthanksmustgotothePathfinderAdvisoryPanel,representingallpartsoftheUKandmadeupofindividualswithawidebreadthofexperience,bothpersonalandprofessional,inovariancancer.

ChairProfessorMichaelPeake,ClinicalLeadfortheNationalCancerRegistrationandAnalysisService;HonoraryProfessorofRespiratoryMedicine,UniversityofLeicester;HonoraryConsultantRespiratoryPhysician,UniversityHospitalsofLeicester;andHonoraryProfessorofRespiratoryMedicine,UniversityCollegeHospital,London

Members• PaulShagouri,relativeadvocate(England)

• DrAndyNordin,PresidentoftheBritishGynaecologicalCancerSocietyandConsultantGynaecologistatTheQueenElizabethTheQueenMotherHospital,EastKent

• NataliePercival,PresidentoftheNationalForumofGynaecologicalOncologyNursesandAdvancedNursePractitionerattheRoyalMarsdenHospital,London

• ProfessorDebbieSharpOBE,ProfessorofPrimaryCareatBristolUniversityandmemberofTargetOvarianCancer’sGPAdvisoryBoard

• DrAlexandraCran-McGreehin,relativeadvocate(Scotland)

• DrRosGlasspool,ChairoftheNationalCancerResearchInstituteOvariansub-groupandConsultantMedicalOncologistattheBeatsonWestofScotlandCancerCentre

• ChristineMitchell,patientadvocate(Scotland)

• SarahBurton,GynaecologicalOncologyClinicalNurseSpecialistattheVelindreCancerCentre,Cardiff

• AnnAdair,patientadvocate(NorthernIreland)

ThisreportwaswrittenbyRebeccaRennisonfromTargetOvarianCancer.

Thank you

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PathfinderEnglandisbasedonthreedifferentsurveys:

• Womeninthegeneralpopulation

• PractisingGPs

• Womenwithovariancancer

Awareness among women in the general populationTheOvarianCancerAwarenessMeasure,avalidatedtool,wasusedtomeasureawarenessofovariancanceramongwomeninthegeneralpopulation.17

Telephoneinterviewswerecarriedoutbetween5Februaryand1March2016.Arandomdigitdiallingsamplingapproachwasusedincluding25percentmobilenumberstoreduceanyagebias(asyoungerwomenarelesslikelytoliveinaccommodationwithalandline).Intotal1042womenlivinginEnglandtookpartinthesurveyand1,343womenacrosstheUKasawhole.

TheresearchwascarriedoutbyOpinionLeaderwhoareamemberoftheInterviewerQualityControlSchemeandhaveMarketResearchQualityStandardsAssociationaccreditation.Allresearchwasconductedbytheirin-housetelephoneresearchteam.

Knowledge and experience among practising GPsAsurveyofpractisingGPsacrosstheUKwasusedtomeasureGPawarenessandexperienceofovariancancer.

Thesurveywascarriedoutonlinebetween26Februaryand5March2016andinrecognitionoftheirtime,GPswerepaidasmallfeetoparticipate.ThesamplewastakenfromthemembershipofDoctors.netwhichisfreeandgivesdoctorsaccesstoforums,ContinuousProfessionalDevelopmentandwiderresources.Doctors.netisaccessedbyapproximatelyoneinthreeUKGPs.TheopportunitytotakepartwasshowntoGPscurrentlypractisingintheUKonthelandingpagefollowingsign-inandinthefinalfewdaysofthesurveyappearedasapop-upalerttoencouragefinalcompletions.Atotalof403GPspractisinginEnglandtookpartinthesurveyand504GPsacrosstheUKasawhole.

TheresearchwascarriedoutbymedeConnectwhoseresearchaudiencespansawiderangeofhealthprofessionalsbothintheUKandglobally.Itwascarriedoutasabespokesurvey.

Methodology

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Women with ovarian cancerThesurveyofwomenwithovariancanceraskedwomenabouttheirexperiencesfromsymptoms,throughtodiagnosisandtreatment.Thesurveywasopentoallwomenwithovariancancerdiagnosedsince2010currentlylivingintheUK(approximately13,000inEnglandand16,000acrosstheUKasawhole).18

Thesurveyranonlinefrom1Aprilto14August2016.ItwaspromotedthroughTargetOvarianCancer’swebsite,digitalmailinglistandsocialmedia.PromotionalpostcardsweresenttoeverycancerunitandcentreacrosstheUK.Intotal304womenwithovariancancerlivinginEnglandtookpartinthesurveyand396womenacrosstheUKasawhole.

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References

1. OfficeforNationalStatistics(2017)Cancerregistrationstatistics,England2015.

2. DepartmentofHealthandPublicHealthEngland(2015)EvaluationoftheBeClearonCancerovariancancerawarenesscampaign.Highlightsfromlocalpilots:14Januaryto10March2013.

3. PublicHealthEngland(2015)BeClearonCancer:ovariancancerawarenessregionalpilotcampaign.Interimevaluationresults.

4. NationalInstituteforHealthandCareExcellence(2013)Familialbreastcancer:classification,careandmanagingbreastcancerandrelatedrisksinpeoplewithafamilyhistoryofbreastcancer.Clinicalguideline[CG164].

5. NHSEngland(2015)Clinicalcommissioningpolicy:genetictestingforBRCA1andBRCA2mutations.

6. NHSEngland(2017)Nationalcancerdrugsfundlist.

7. NationalInstituteforHealthandCareExcellence(2016)Olaparibformaintenancetreatmentofrelapsed,platinum-sensitive,BRCAmutation-positiveovarian,fallopiantubeandperitonealcancerafterresponsetosecond-lineorsubsequentplatinumbasedchemotherapy.

8. NationalCancerRegistrationandAnalysisService(2015)Gynaecologicalcancerprofiles.

9. NationalInstituteforHealthandCareExcellence(2011)Ovariancancer:recognitionandinitialmanagementofovariancancer.Clinicalguideline122.

10. Zhang,S.etal(2011)FrequenciesofBRCA1andBRCA2mutationsamong1,342unselectedpatientswithinvasiveovariancancer.GynaecologicOncology121(2):353-357.

11. TargetOvarianCancer(2016)Genetictestingandhereditaryovariancancer:aguideforwomenwithovariancancerandtheirfamilies.

12. NationalInstituteforHealthandCareExcellence(2011)Ovariancancer:recognitionandinitialmanagementofovariancancer.Clinicalguideline122.

13. DuBois,A.etal(2005)Patternofcareandimpactofparticipationinclinicalstudiesontheoutcomesinovariancancer.InternationalJournalofGynaecologicalCancer,15:183-191.

14. QualityHealth(2015)NationalCancerPatientExperienceSurvey2015.Breakdownforovariancancerandfallopiantubecancerprovidedonrequest.

15. IndependentCancerTaskforce(2015)Achievingworld-classcanceroutcomes:astrategyforEngland2015-2020.

16. ChiefMedicalOfficer(2015)TheAnnualReportoftheChiefMedicalOfficer,2014.Thehealthofthe51%:women.

17. TheOvarianCancerAwarenessMeasureisavalidatedtoolbasedonthewiderCancerAwarenessMeasuredevelopedbyCancerResearchUK,UniversityCollegeLondon,King’sCollegeLondonandOxfordUniversity.

18. NationalCancerIntelligenceNetwork(2010)One,fiveandtenyearcancerprevalencebyCancerNetwork,UK,2006.

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2 Angel Gate, London, EC1V 2PT

020 7923 5470

[email protected]

targetovariancancer.org.uk

facebook.com/TargetOvarianCancer

@TargetOvarian

©Target Ovarian Cancer 2017

Target Ovarian Cancer is a company limited by guarantee, registered in England and Wales (No. 6619981). Registered office: 2 Angel Gate, London EC1V 2PT.

Registered charity numbers 1125038 (England and Wales) and SC042920 (Scotland).

Ovarian cancer can be devastating. It kills 11 women every single day in the UK and survival rates in the UK are among the worst in Europe. But there is hope – Target Ovarian Cancer.

We are the authority on ovarian cancer. We work with women, family members and health professionals to ensure we target the areas that matter most for those living and working with ovarian cancer.

As the UK’s leading ovarian cancer charity we work to improve early diagnosis, we fund life saving research and we provide much needed support to women with ovarian cancer. We’re the only charity fighting ovarian cancer on all three of these fronts, across all four nations of the UK.