ati khaled khalilia
TRANSCRIPT
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ATISUBJECTS FOR THE PRACTICAL EXAMINATION
ANESTHESIA AND INTENSIVE CARE
MEDICINE 4TH
YEAR
Khaled khalilia
4th
year
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SUBJECTS FOR THE PRACTICAL EXAMINATION
ANESTHESIA AND INTENSIVE CARE
MEDICINE 4TH
YEAR
1.1The technique of chest compression.
1.2Desobstruction of the upper respiratory airway in case of liquid foreign bodies.
1.3Desobstruction of the upper respiratory airway in case of solid foreign bodies.
1.4Maneuvers of upper respiratory airway opening in a patient without suspicion of
cervical spine lesion.
1.5Maneuvers of upper respiratory airway opening the upper respiratory airway in
a patient with suspicion of cervical spine lesion.
1.6Evaluation of spontaneous breathing.
1.7Pulse evaluation.
1.8The technique ofmouth to mouth artificial respiration.
1.9Recovery position.
1.10 Defibrillation technique.
2.1 Peripheral venous accessindications, technique, advantages, disadvantages.2.2 Central venous accessindications, technique, advantages, disadvantages.
2.3 Arterial catheterindications, technique, advantages, disadvantages.2.4 Oxygen therapyindications, administration systems, adverse effects.
2.5 Pulse oximetry.2.6 Monitorization of arterial blood pressure.
2.7 Monitorization of body temperature.
2.8 Normal salineindications, advantages, adverse effects.2.9 Ringer lactate solutionindications, advantages, adverse effects.
2.10 Water balance.
2.11 Macromolecular solutions indications, advantages, adverse effects,examples.
2.12 Dopaminemechanism of action, indications, adverse effects.2.13 Dobutaminemechanism of action, indications, adverse effects.
2.14 Adrenalinemechanism of action, indications, adverse effects.2.15 Noradrenalinemechanism of action, indications, adverse effects.
3. Clinical case
Associate Professor Ioana Grigoras, MD, PhD
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1.The technique of chest compression.
Use heel of two hands placed above center of chest (superior to xiphoid). Depress chest at least 4- 5 cm
Compression rate at least 100 times/minute
Compress 30 times within 18 seconds
Compression to Ventilation Ratio 30:2
Depth: 4-6 cm
Frequency: 100/min
Ratio: 30:2
Video :http://www.youtube.com/watch?v=qSsHcdy4GnA
More iformation:http://www.resus.org.au/policy/guidelines/section_13/guideline-13-6dec10.pdf
http://www.youtube.com/watch?v=qSsHcdy4GnAhttp://www.youtube.com/watch?v=qSsHcdy4GnAhttp://www.youtube.com/watch?v=qSsHcdy4GnAhttp://www.resus.org.au/policy/guidelines/section_13/guideline-13-6dec10.pdfhttp://www.resus.org.au/policy/guidelines/section_13/guideline-13-6dec10.pdfhttp://www.resus.org.au/policy/guidelines/section_13/guideline-13-6dec10.pdfhttp://www.resus.org.au/policy/guidelines/section_13/guideline-13-6dec10.pdfhttp://www.youtube.com/watch?v=qSsHcdy4GnA -
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2.Desobstruction of the upper respiratory airway in case
of liquid foreign bodies.
Look, listen,feel, ABCDE Abdominal movements, airflow via mouth and nose
Oropharyngeal tube: coma patient
Nasophyryngeal tube.
Tracheal intubation
The Yankauer suctionis anoralsuctioningtool used in medicalprocedures.This tool is used to suctionoropharyngealsecretions in
order to prevent. Remove the liquid,saliva.
Video: yankauer suction:http://www.youtube.com/watch?v=CQ2TN3njTJg
http://en.wikipedia.org/wiki/Mouthhttp://en.wikipedia.org/wiki/Mouthhttp://en.wikipedia.org/wiki/Suction_(medicine)http://en.wikipedia.org/wiki/Suction_(medicine)http://en.wikipedia.org/wiki/Suction_(medicine)http://en.wikipedia.org/wiki/Human_pharynxhttp://en.wikipedia.org/wiki/Human_pharynxhttp://en.wikipedia.org/wiki/Human_pharynxhttp://www.youtube.com/watch?v=CQ2TN3njTJghttp://www.youtube.com/watch?v=CQ2TN3njTJghttp://www.youtube.com/watch?v=CQ2TN3njTJghttp://www.youtube.com/watch?v=CQ2TN3njTJghttp://en.wikipedia.org/wiki/Human_pharynxhttp://en.wikipedia.org/wiki/Suction_(medicine)http://en.wikipedia.org/wiki/Mouth -
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3.Desobstruction of the upper respiratory airway in case
of solid foreign bodies. ( i dunno exactly)
Traumatic causes
Laryngeal stenosis Airway burn Acute laryngeal injury
Facial trauma (mandibular or maxillary
fractures)
Hemorrhage
Infections Suppurative parotitis
Retropharyngeal abscess Tonsillar hypertrophy
Ludwigs angina
Epiglottitis Laryngitis
Laryngotracheobronchitis (croup)
Iatrogenic causes
Tracheal stenosis post-tracheostomy Tracheal stenosis post-intubation Mucous ball from transtracheal catheter
Foreign bodies
Vocal cord paralysis
Tumors Laryngeal tumors (benign or malignant)
Laryngeal papillomatosis
TrachealAngioedema
Anaphylactic reactions
C1 inhibitor deficiency Angiotensin-converting enzyme inhibitors
A foreign body may become lodged in the larynx, trachea, or bronchus. The rightbronchus is more commonly affected than the left because of the lesser angle ofdivergence relative to the left bronchus and because of its greater diameter.7,10 Largerforeign bodies may become lodged in the larynx. Laryngotracheal foreign bodies areassociated with increased morbidity and mortality.1
Signs and symptoms associated with foreign body aspiration occur in 3 phases.
Stage 1.Choking, coughing, gasping, and respiratory distress develop because ofairway obstruction. Choking lasts for a few seconds to several minutes after the episodeand may be self-limited.
Stage 2.Acute symptoms may be followed by a temporary quiescent phase in which thepatient may not have any symptoms.
Stage 3.During the last phase, symptoms of complications such as infection maydevelop.
A foreign body that completely obstructs the upper airway is an immediate threatto life and must be removed immediately.
The head-down back-blow maneuver, the first step recommended for infants,combines the force of gravity with the force the chest compression generates toexpel intrathoracic air.
Heimnlich maneuver
cricothyroidoctomy
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4.Maneuvers of upper respiratory airway opening in a
patient without suspicion of cervical spine lesion.
Safe position Head extension
Chin lift
Head lift
Jaw thrust
Mouth opening
Head extension Finger sweep maneuver, remove forign body.
In order to have a better view :
Video 1:http://www.youtube.com/watch?v=etPa9oxVWyUVideo 2:http://www.youtube.com/watch?v=2fnS8mtqzms
Video 3:http://www.youtube.com/watch?v=oTHe8qKoMqo
Video 4:http://www.youtube.com/watch?v=BuXV2ubmf20
http://www.youtube.com/watch?v=etPa9oxVWyUhttp://www.youtube.com/watch?v=etPa9oxVWyUhttp://www.youtube.com/watch?v=etPa9oxVWyUhttp://www.youtube.com/watch?v=2fnS8mtqzmshttp://www.youtube.com/watch?v=2fnS8mtqzmshttp://www.youtube.com/watch?v=2fnS8mtqzmshttp://www.youtube.com/watch?v=oTHe8qKoMqohttp://www.youtube.com/watch?v=oTHe8qKoMqohttp://www.youtube.com/watch?v=oTHe8qKoMqohttp://www.youtube.com/watch?v=BuXV2ubmf20http://www.youtube.com/watch?v=BuXV2ubmf20http://www.youtube.com/watch?v=BuXV2ubmf20http://www.youtube.com/watch?v=BuXV2ubmf20http://www.youtube.com/watch?v=oTHe8qKoMqohttp://www.youtube.com/watch?v=2fnS8mtqzmshttp://www.youtube.com/watch?v=etPa9oxVWyU -
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5.Maneuvers of upper respiratory airway opening theupper respiratory airway in a patient with suspicion of
cervical spine lesion.
See the video:http://www.youtube.com/watch?v=DJY89_jC_ZYMore information:http://www.primary-surgery.org/ps/vol2/html/sect0226.html
http://www.youtube.com/watch?v=DJY89_jC_ZYhttp://www.youtube.com/watch?v=DJY89_jC_ZYhttp://www.youtube.com/watch?v=DJY89_jC_ZYhttp://www.primary-surgery.org/ps/vol2/html/sect0226.htmlhttp://www.primary-surgery.org/ps/vol2/html/sect0226.htmlhttp://www.primary-surgery.org/ps/vol2/html/sect0226.htmlhttp://www.primary-surgery.org/ps/vol2/html/sect0226.htmlhttp://www.youtube.com/watch?v=DJY89_jC_ZY -
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6.Evaluation of spontaneous breathing.
ABCDE Tension pneumothorax: needle thoracostomy folowed by drainage
Flail chest:ventilitation and stabilization and dressing
Hemothorax: intercostal drain insertion
Pneumothorax:intercostal drain insertion Open pneumothorax: Thoracostomy tube
Pericardial temponade: pericardiocenthesis
Check the following: Look,listen,feel
Lung
Chest wall
Diaphragm
Chest movements
Auscultation Percusion
Airway potency and breathing
.
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7.Pulse evaluation.? (from wikipedia )
Rate:Normal pulse ratesat rest,in beats per minute (BPM)
Children (1-10 years): 70-130Children over 10 years and adults: 60-100
Athletes: 40-60
Rythem: A normal pulse is regular in rhythm and force. Anirregular pulse may be due tosinus arrhythmia,premature
beats,ectopic beats,atrial fibrillation,paroxysmal atrial
tachycardia,atrial flutter,partial heart block etc.
Volume: The degree of expansion displayed by artery duringdiastolic and systolic state is called volume. It also known as
amplitude, expansion or size of pulse.
Hypokinetic pulse:A weak pulse signifies narrowpulse pressure.It may be due to lowcardiac output (as seen inshock,congestive
cardiac failure),hypovolemia,valvular heart disease (such asaortic
outflow tract obstruction,mitral stenosis,aortic arch syndrome)etc
Hyperkinetic pulse: A bounding pulse signifies high pulsepressure. It may be due to lowperipheral resistance (as seen
infever,anemia,thyrotoxicosis,hyperkinetic heart syndrome,A-V
fistula,Paget's diseaseberiberi,liver cirrhosis), increased cardiac
output, increasedstroke volume (as seen in anxiety,
exercise,complete heart block,aortic regurgitation), decreased
distensibility of arterial system (as seen
inatherosclerosis,hypertension andcoarctation of aorta).
http://en.wikipedia.org/wiki/Heart_rate#At_resthttp://en.wikipedia.org/wiki/Sinus_arrhythmiahttp://en.wikipedia.org/w/index.php?title=Premature_beats&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Premature_beats&action=edit&redlink=1http://en.wikipedia.org/wiki/Ectopic_beatshttp://en.wikipedia.org/wiki/Atrial_fibrillationhttp://en.wikipedia.org/w/index.php?title=Paroxysmal_atrial_tachycardia&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Paroxysmal_atrial_tachycardia&action=edit&redlink=1http://en.wikipedia.org/wiki/Atrial_flutterhttp://en.wikipedia.org/w/index.php?title=Partial_heart_block&action=edit&redlink=1http://en.wikipedia.org/wiki/Pulse_pressurehttp://en.wikipedia.org/wiki/Cardiac_outputhttp://en.wikipedia.org/wiki/Shock_(circulatory)http://en.wikipedia.org/wiki/Congestive_cardiac_failurehttp://en.wikipedia.org/wiki/Congestive_cardiac_failurehttp://en.wikipedia.org/wiki/Hypovolemiahttp://en.wikipedia.org/wiki/Valvular_heart_diseasehttp://en.wikipedia.org/w/index.php?title=Aortic_outflow_tract_obstruction&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Aortic_outflow_tract_obstruction&action=edit&redlink=1http://en.wikipedia.org/wiki/Mitral_stenosishttp://en.wikipedia.org/wiki/Aortic_arch_syndromehttp://en.wikipedia.org/wiki/Peripheral_resistancehttp://en.wikipedia.org/wiki/Feverhttp://en.wikipedia.org/wiki/Anemiahttp://en.wikipedia.org/wiki/Thyrotoxicosishttp://en.wikipedia.org/w/index.php?title=Hyperkinetic_heart_syndrome&action=edit&redlink=1http://en.wikipedia.org/wiki/Arteriovenous_fistulahttp://en.wikipedia.org/wiki/Arteriovenous_fistulahttp://en.wikipedia.org/wiki/Paget%27s_diseasehttp://en.wikipedia.org/wiki/Liver_cirrhosishttp://en.wikipedia.org/wiki/Stroke_volumehttp://en.wikipedia.org/wiki/Complete_heart_blockhttp://en.wikipedia.org/wiki/Aortic_regurgitationhttp://en.wikipedia.org/wiki/Atherosclerosishttp://en.wikipedia.org/wiki/Hypertensionhttp://en.wikipedia.org/wiki/Coarctation_of_aortahttp://en.wikipedia.org/wiki/Coarctation_of_aortahttp://en.wikipedia.org/wiki/Hypertensionhttp://en.wikipedia.org/wiki/Atherosclerosishttp://en.wikipedia.org/wiki/Aortic_regurgitationhttp://en.wikipedia.org/wiki/Complete_heart_blockhttp://en.wikipedia.org/wiki/Stroke_volumehttp://en.wikipedia.org/wiki/Liver_cirrhosishttp://en.wikipedia.org/wiki/Paget%27s_diseasehttp://en.wikipedia.org/wiki/Paget%27s_diseasehttp://en.wikipedia.org/wiki/Arteriovenous_fistulahttp://en.wikipedia.org/wiki/Arteriovenous_fistulahttp://en.wikipedia.org/w/index.php?title=Hyperkinetic_heart_syndrome&action=edit&redlink=1http://en.wikipedia.org/wiki/Thyrotoxicosishttp://en.wikipedia.org/wiki/Anemiahttp://en.wikipedia.org/wiki/Feverhttp://en.wikipedia.org/wiki/Peripheral_resistancehttp://en.wikipedia.org/wiki/Aortic_arch_syndromehttp://en.wikipedia.org/wiki/Mitral_stenosishttp://en.wikipedia.org/w/index.php?title=Aortic_outflow_tract_obstruction&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Aortic_outflow_tract_obstruction&action=edit&redlink=1http://en.wikipedia.org/wiki/Valvular_heart_diseasehttp://en.wikipedia.org/wiki/Hypovolemiahttp://en.wikipedia.org/wiki/Congestive_cardiac_failurehttp://en.wikipedia.org/wiki/Congestive_cardiac_failurehttp://en.wikipedia.org/wiki/Shock_(circulatory)http://en.wikipedia.org/wiki/Cardiac_outputhttp://en.wikipedia.org/wiki/Pulse_pressurehttp://en.wikipedia.org/w/index.php?title=Partial_heart_block&action=edit&redlink=1http://en.wikipedia.org/wiki/Atrial_flutterhttp://en.wikipedia.org/w/index.php?title=Paroxysmal_atrial_tachycardia&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Paroxysmal_atrial_tachycardia&action=edit&redlink=1http://en.wikipedia.org/wiki/Atrial_fibrillationhttp://en.wikipedia.org/wiki/Ectopic_beatshttp://en.wikipedia.org/w/index.php?title=Premature_beats&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Premature_beats&action=edit&redlink=1http://en.wikipedia.org/wiki/Sinus_arrhythmiahttp://en.wikipedia.org/wiki/Heart_rate#At_rest -
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8.The technique ofmouthto mouth artificial respiration.
Assume thatPatient has pulse and CPR is not necessary!!!Resuscitation by inducing artificial respiration consists of two actions:
(1) establishing and maintaining an open air passage from the upperrespiratory tract (mouth,throat, andpharynx)to thenlungs .
(2) exchanging air andcarbon dioxide in the terminal air sacs of the lungswhile theheart is still functioning.
Safe position
Head tilt
Chin lift Jaw thrust
Mouth opening
While keeping the head tilted, seal the victims mouth with your mouthand seal the patients nose with your fingers. Blow air into the mouthfor at least 1 second. You must give two blows initially.
Another thing to consider in providing mouth to mouth in infants.
Considering that they are small, there is no need to pinch the nose.The nose can be sealed by including it in your blows as you blow onthe infants mouth. Make sure also not to put to much air as you blowon infants. Only use the air from your mouth and not from yourdiapraghm.
Video:http://www.youtube.com/watch?v=Lbh7g-m_bwQ
http://www.britannica.com/EBchecked/topic/499856/resuscitationhttp://www.britannica.com/EBchecked/topic/395124/mouthhttp://www.britannica.com/EBchecked/topic/455238/pharynxhttp://www.britannica.com/EBchecked/topic/351473/lunghttp://www.britannica.com/EBchecked/topic/94900/carbon-dioxidehttp://www.britannica.com/EBchecked/topic/258344/hearthttp://www.youtube.com/watch?v=Lbh7g-m_bwQhttp://www.youtube.com/watch?v=Lbh7g-m_bwQhttp://www.britannica.com/EBchecked/topic/258344/hearthttp://www.britannica.com/EBchecked/topic/94900/carbon-dioxidehttp://www.britannica.com/EBchecked/topic/351473/lunghttp://www.britannica.com/EBchecked/topic/455238/pharynxhttp://www.britannica.com/EBchecked/topic/395124/mouthhttp://www.britannica.com/EBchecked/topic/499856/resuscitation -
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9.Recovery position.
1. Kneel next to the person. Place
the arm closest to you straight outfrom the body. Position the far
arm with the back of the handagainst the near cheek.
2. Grab and bend the person's far
knee.
3. Protecting the head with onehand, gently roll the person
toward you by pulling the far kneeover and to the ground.
4. Tilt the head up slightly so that
the airway is open. Make sure thatthe hand is under the cheek. Place
a blanket or coat over the person(unless he or she has a heat illness
or fever) and stay close until helparrives.
Infant Recovery Position
Place the infant face down over your arm with the head slightly lower than
the body. Support the head and neck with your hand, keeping the mouth andnose clear. Wait for help to arrive.
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10. Defibrillation technique : check the script for moreinfo
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1. Peripheral venous accessindications, technique, advantages,
disadvantages.
Indication:
Emergency
Operation
Radiology
Hydration
Nutritional
Medication
Cardiac arrest
Blood products
Long term AB-therapy
Complication:
Infection
Phlebitis
Bleeding
Air embolism
infiltration
Advantages:
Simple technique
Short time (quick)
No interruption of chestcompression
Low costDisadvantages:
Long time of drug circulation
Easy to lose venous accessSites:
Upper extremity: Cephalic vein,median cubital or Basilic vein
Low extremity: great
saphenus vein, MedianMarginal Vein
Scalp: Small superficial vein
Technique:
A.ConsiderLocal Anesthesiaat catheter insertion site (Lidocaine)B.Consider limb warming prior to IV cannula insertionC.Immobilize the extremityD.stretch the vein Flex the wrist to extend the dorsal hand veinsE.Apply aTourniquetto proximal veinF.Antiseptic to cannulation siteG.Flush the needle catheter with sterile saline
H.Enter Skin1. Puncture distal to the site2. Enter at 45 degrees with bevel down3. Pull the skin to the side while entering skin4. Avoid entering the vein with needle
I. Cannulate vein, remove the needle and the tourniquet
http://www.fpnotebook.com/Surgery/Pharm/LclSknAnsths.htmhttp://www.fpnotebook.com/Surgery/Pharm/LclSknAnsths.htmhttp://www.fpnotebook.com/Surgery/Pharm/LclSknAnsths.htmhttp://www.fpnotebook.com/ER/Pharm/Trnqt.htmhttp://www.fpnotebook.com/ER/Pharm/Trnqt.htmhttp://www.fpnotebook.com/ER/Pharm/Trnqt.htmhttp://www.fpnotebook.com/ER/Pharm/Trnqt.htmhttp://www.fpnotebook.com/Surgery/Pharm/LclSknAnsths.htm -
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Peripheral venous access:Video 1:http://www.youtube.com/watch?v=nVem1__qW14
Video 2:http://www.youtube.com/watch?v=IMSMvAMHfL8
Video 3:http://www.youtube.com/watch?v=9eHimrGgnm4
http://www.youtube.com/watch?v=nVem1__qW14http://www.youtube.com/watch?v=nVem1__qW14http://www.youtube.com/watch?v=nVem1__qW14http://www.youtube.com/watch?v=IMSMvAMHfL8http://www.youtube.com/watch?v=IMSMvAMHfL8http://www.youtube.com/watch?v=IMSMvAMHfL8http://www.youtube.com/watch?v=9eHimrGgnm4http://www.youtube.com/watch?v=9eHimrGgnm4http://www.youtube.com/watch?v=9eHimrGgnm4http://www.youtube.com/watch?v=9eHimrGgnm4http://www.youtube.com/watch?v=IMSMvAMHfL8http://www.youtube.com/watch?v=nVem1__qW14 -
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2. Central venous accessindications, technique, advantages,
disadvantages.Indication:
Medication
Fluids adm. Bloodtests
Cardiovascular measurements
Long term AB
Long term pain medicaments
Longterm parenteral nutrition
Dialysis
Plasmaphoresis
Complication: Infection
Phlebitis
Bleeding
Air embolism
Infiltration
Pneumothorax
Thrombosis(DVT and vein)
Arrhythmias
Advantages:
Short time of drug circulation
Safe access Longlasting access
Hypertonic solution
Monitor treatment response
Evaluate heart filling (RV)Disadvantages:
Temporary interruption ofcardiac message
Long installation time
Complication rate Require special equipment
Sites of insertion:
Neck: internal jugular vein
Chest: subclavian vein oraxillary vein
Goin: femoral vein
Non tunneled: fixed in place
Tunneled: under the skin, monoluminal,biluminal, triluminal
CathetherInternal jugular vein External Subclavian vein
Axillary veinBrachial vein.
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Central vein access:
Video 1:http://www.youtube.com/watch?v=H3mJjtTk27Q
Video 2:http://www.youtube.com/watch?v=7YRXirk--hoVideo 3:http://www.youtube.com/watch?v=Sgypvr2fNq0
Video 4:http://www.youtube.com/watch?v=LkPCuJKREyo
http://www.youtube.com/watch?v=H3mJjtTk27Qhttp://www.youtube.com/watch?v=H3mJjtTk27Qhttp://www.youtube.com/watch?v=H3mJjtTk27Qhttp://www.youtube.com/watch?v=7YRXirk--hohttp://www.youtube.com/watch?v=7YRXirk--hohttp://www.youtube.com/watch?v=7YRXirk--hohttp://www.youtube.com/watch?v=Sgypvr2fNq0http://www.youtube.com/watch?v=Sgypvr2fNq0http://www.youtube.com/watch?v=Sgypvr2fNq0http://www.youtube.com/watch?v=LkPCuJKREyohttp://www.youtube.com/watch?v=LkPCuJKREyohttp://www.youtube.com/watch?v=LkPCuJKREyohttp://www.youtube.com/watch?v=LkPCuJKREyohttp://www.youtube.com/watch?v=Sgypvr2fNq0http://www.youtube.com/watch?v=7YRXirk--hohttp://www.youtube.com/watch?v=H3mJjtTk27Q -
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3. Arterial catheter (arterial line) indications, technique,
advantages, disadvantages.Indication:
Continuous direct blood
pressure monitoringarterial blood gas sampling
Central venous pressure
R.atrium pressure
Pressure in pulmonary artery
Cardiac output
Stroke volume
O2-cosumption and delivery
Vascular resistance
Advantages:Shock diagnosis
Monitor treatment responseDisadvantages:
Complication
Required special equipment
Complication: Infection
Pneumothorax
Hematoma,bleeding
Thrombosis
Aneurysm
FistulaSite of insertion:
Radial artery
Brachial artery Femoral artery
Ulnar artery
Dorsalis pedis artery
Technique:
1. Arm is abducted and the wrist hyperextended
2. Local skin anesthesia is then administered
3. Proximal to styloid process of the radius, a small incision is made over the skin
4. Subcutaneous tissue is then tunneled using forceps
5. At 45 angle, an 18-21 guage needle should be introduced
6. Radial sheath of 23cm long and 4-6Fr size should then be introduced
7. Using a rotating arm board under the shoulder facilitates ease of movement and
placement of radial sheath
8. Through sidearm of the sheath, 5000U ofheparinshould be administered
9. To reduce spasm, 500 micrograms ofdiltiazemcan also be administered
10. Coronary catheters are then advanced along the guidewire into aorta
11. Left and right coronary arteries are then catheterized using Judkins, Amplatz or
multipurpose catheter
http://emedicine.medscape.com/article/1902703-overviewhttp://www.wikidoc.org/index.php/Heparinhttp://www.wikidoc.org/index.php/Heparinhttp://www.wikidoc.org/index.php/Heparinhttp://www.wikidoc.org/index.php/Diltiazemhttp://www.wikidoc.org/index.php/Diltiazemhttp://www.wikidoc.org/index.php/Diltiazemhttp://www.wikidoc.org/index.php/Diltiazemhttp://www.wikidoc.org/index.php/Heparinhttp://emedicine.medscape.com/article/1902703-overview -
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12. Hemostasis is achieved by direct pressure at the puncture site at the end of the
procedure after removal of radial sheath
13. Radial pulse should be monitored after the procedure for several hours regularly.
Arterial cathether:More info:http://www.arrowintl.com/documents/pdf/literature/eng-sac-c0507.pdf
Video 1:http://www.youtube.com/watch?v=CLxxM4yltwo
Video 2:http://www.youtube.com/watch?v=6--8J4iqGEY
Video 3:http://www.youtube.com/watch?v=qv54USEYNzw
http://www.arrowintl.com/documents/pdf/literature/eng-sac-c0507.pdfhttp://www.arrowintl.com/documents/pdf/literature/eng-sac-c0507.pdfhttp://www.arrowintl.com/documents/pdf/literature/eng-sac-c0507.pdfhttp://www.youtube.com/watch?v=CLxxM4yltwohttp://www.youtube.com/watch?v=CLxxM4yltwohttp://www.youtube.com/watch?v=CLxxM4yltwohttp://www.youtube.com/watch?v=6--8J4iqGEYhttp://www.youtube.com/watch?v=6--8J4iqGEYhttp://www.youtube.com/watch?v=6--8J4iqGEYhttp://www.youtube.com/watch?v=qv54USEYNzwhttp://www.youtube.com/watch?v=qv54USEYNzwhttp://www.youtube.com/watch?v=qv54USEYNzwhttp://www.youtube.com/watch?v=qv54USEYNzwhttp://www.youtube.com/watch?v=6--8J4iqGEYhttp://www.youtube.com/watch?v=CLxxM4yltwohttp://www.arrowintl.com/documents/pdf/literature/eng-sac-c0507.pdf -
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4. Oxygen therapy indications, administration systems,
adverse effects.
chronic indication:
COPD (chronic bronchitis andemphysema)
Breathless patient
Endstage cardiac failure
Endstage respiratory failure
CancerAcute indication:
Emergency, hospital and firstaid
Resuscitation
TraumaAnaphylaxis
Hemorrhage
Shock
Hypothermia
Hypoxemia
Cluster headache
Fire risk
Asthma
PneumoniaRDS
Administration:
Nasal canula 5L/min
Face mask 50 %
Venture mask
Mask+ reservoir Bag 70%
Mask + one way valves 80%
Nasal canula 100%
Very tight masksanesthesiaPocket mask
Bag-valve-mask (cyaidepoisoning)
Filtered o2-mask
Storage and sources:
Liquid and compressed gas
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Oxygen therapy:Video 1:http://www.youtube.com/watch?v=FT7t9hroLLgVideo 2:http://www.youtube.com/watch?v=Nc2zl2SeQNo
Video 3:http://www.youtube.com/watch?v=MNzCfO7Z0Fk
http://www.youtube.com/watch?v=FT7t9hroLLghttp://www.youtube.com/watch?v=FT7t9hroLLghttp://www.youtube.com/watch?v=FT7t9hroLLghttp://www.youtube.com/watch?v=Nc2zl2SeQNohttp://www.youtube.com/watch?v=Nc2zl2SeQNohttp://www.youtube.com/watch?v=Nc2zl2SeQNohttp://www.youtube.com/watch?v=MNzCfO7Z0Fkhttp://www.youtube.com/watch?v=MNzCfO7Z0Fkhttp://www.youtube.com/watch?v=MNzCfO7Z0Fkhttp://www.youtube.com/watch?v=MNzCfO7Z0Fkhttp://www.youtube.com/watch?v=Nc2zl2SeQNohttp://www.youtube.com/watch?v=FT7t9hroLLg -
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5.Pulse oximetry:
Pulse oximetryis anon-invasive method for monitoring a patient'sO2saturation.
a sensor is placed on a thin part of the patient's body, usuallyafingertiporearlobe,or in the case of aninfant,across a foot.
The principle of pulse oximetry is based on the red and infraredlight absorption characteristics of oxygenated and deoxygenated
hemoglobin. Oxygenated hemoglobin absorbs more infrared light
and allows more red light to pass through. Deoxygenated (or
reduced) hemoglobin absorbs more red light and allows more
infrared light to pass through. Red light is in the 600-750 nmwavelength light band. Infrared light is in the 850-1000 nm
wavelength light band. (not very important !! general knowledge)
Indication:
Monitor o2-saturation
Sleep disorders
Sleep apnea
Emergency Surgery
COPD
Asthma
Pneumonia
Congestive heart failure
Anemia
Lung cancer
During anaesthesia
Advantages: Detect arrhythmias
Evaluation of A.bloodoxygenation
Measure HR
Evaluate peripheral perfusion
Non-invasive Transportable
Detect ventilation abnormalitiesDisadvantages:
Movementartefacts
Painted nailsdont use
Low accuracy of bloodoxygenation
tissue perfusion pressure
cant measure
http://en.wikipedia.org/wiki/Invasiveness_of_surgical_procedureshttp://en.wikipedia.org/wiki/Fingertiphttp://en.wikipedia.org/wiki/Fingertiphttp://en.wikipedia.org/wiki/Fingertiphttp://en.wikipedia.org/wiki/Earlobehttp://en.wikipedia.org/wiki/Earlobehttp://en.wikipedia.org/wiki/Earlobehttp://en.wikipedia.org/wiki/Infanthttp://en.wikipedia.org/wiki/Infanthttp://en.wikipedia.org/wiki/Earlobehttp://en.wikipedia.org/wiki/Fingertiphttp://en.wikipedia.org/wiki/Invasiveness_of_surgical_procedures -
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Pulse oxymetry:
More info:http://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdf
Video 1:http://www.youtube.com/watch?v=9PSXruEjBlY
Video 2:http://www.youtube.com/watch?v=NJwiDz4NquI
Video 3:http://www.youtube.com/watch?v=Tsj7q-CkojI
http://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdfhttp://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdfhttp://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdfhttp://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdfhttp://www.youtube.com/watch?v=9PSXruEjBlYhttp://www.youtube.com/watch?v=9PSXruEjBlYhttp://www.youtube.com/watch?v=9PSXruEjBlYhttp://www.youtube.com/watch?v=NJwiDz4NquIhttp://www.youtube.com/watch?v=NJwiDz4NquIhttp://www.youtube.com/watch?v=NJwiDz4NquIhttp://www.youtube.com/watch?v=Tsj7q-CkojIhttp://www.youtube.com/watch?v=Tsj7q-CkojIhttp://www.youtube.com/watch?v=Tsj7q-CkojIhttp://www.youtube.com/watch?v=Tsj7q-CkojIhttp://www.youtube.com/watch?v=NJwiDz4NquIhttp://www.youtube.com/watch?v=9PSXruEjBlYhttp://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdfhttp://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdf -
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6.Monitoring of arterial blood pressure.
Non-invasive:
Palpation: A minimum systolic value can be roughly estimatedbypalpation, most often used inemergency situations, but should be usedwith caution. The diastolic blood pressure cannot be estimated by this method
Auscultation: uses astethoscope and asphygmomanometer. Thiscomprises an inflatable (Riva-Rocci)cuffplaced around the upperarm at
roughly the same vertical height as the heart, attached to a mercuryoraneroidmanometer
Oscilometric:requires less skill than the auscultatory technique and may besuitable for use by untrained staff and for automated patient home monitoring.
CNAP:Continuous Noninvasive Arterial Pressure.
PWV:pulse wave velocityprincipleInvasive:
This technique involves direct measurement of arterial pressure byinserting a cannula needle in a suitable artery. The cannula must be
connected to a sterile, fluid-filled system, which is connected to an
electronic patient monitor. (usuallyradial,femoral,dorsalis
pedis orbrachial). Used inintensive care medicine,anesthesiology.
Advantages:
Blood sample
Repeatable
Real time measurement
Accuracy (high)
Obtain other
Disadvantages:
Complication:ischemia,thrombosis,bleeding,infection.
Require experience
Require special equipment
More info: https://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-blood
Video 1:http://www.youtube.com/watch?v=WHXP339YjF0
Video 2:http://www.youtube.com/watch?v=5TahRMklod8
Video 3:http://www.youtube.com/watch?v=YM3iXS146Yc
http://en.wikipedia.org/wiki/Palpationhttp://en.wikipedia.org/wiki/Emergency_medical_servicehttp://en.wikipedia.org/wiki/Stethoscopehttp://en.wikipedia.org/wiki/Sphygmomanometerhttp://en.wikipedia.org/wiki/Scipione_Riva-Roccihttp://en.wikipedia.org/wiki/Scipione_Riva-Roccihttp://en.wikipedia.org/wiki/Scipione_Riva-Roccihttp://en.wikipedia.org/wiki/Cuffhttp://en.wikipedia.org/wiki/Armhttp://en.wikipedia.org/wiki/Aneroidhttp://en.wikipedia.org/wiki/Aneroidhttp://en.wikipedia.org/wiki/Continuous_Noninvasive_Arterial_Pressurehttp://en.wikipedia.org/wiki/Continuous_Noninvasive_Arterial_Pressurehttp://en.wikipedia.org/wiki/Pulse_wave_velocityhttp://en.wikipedia.org/wiki/Radial_arteryhttp://en.wikipedia.org/wiki/Femoral_arteryhttp://en.wikipedia.org/wiki/Dorsalis_pedis_arteryhttp://en.wikipedia.org/wiki/Dorsalis_pedis_arteryhttp://en.wikipedia.org/wiki/Brachial_arteryhttp://en.wikipedia.org/wiki/Intensive_care_medicinehttp://en.wikipedia.org/wiki/Anesthesiologyhttps://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-bloodhttps://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-bloodhttps://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-bloodhttp://www.youtube.com/watch?v=WHXP339YjF0http://www.youtube.com/watch?v=WHXP339YjF0http://www.youtube.com/watch?v=WHXP339YjF0http://www.youtube.com/watch?v=5TahRMklod8http://www.youtube.com/watch?v=5TahRMklod8http://www.youtube.com/watch?v=5TahRMklod8http://www.youtube.com/watch?v=YM3iXS146Ychttp://www.youtube.com/watch?v=YM3iXS146Ychttp://www.youtube.com/watch?v=YM3iXS146Ychttp://www.youtube.com/watch?v=YM3iXS146Ychttp://www.youtube.com/watch?v=5TahRMklod8http://www.youtube.com/watch?v=WHXP339YjF0https://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-bloodhttps://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-bloodhttp://en.wikipedia.org/wiki/Anesthesiologyhttp://en.wikipedia.org/wiki/Intensive_care_medicinehttp://en.wikipedia.org/wiki/Brachial_arteryhttp://en.wikipedia.org/wiki/Dorsalis_pedis_arteryhttp://en.wikipedia.org/wiki/Dorsalis_pedis_arteryhttp://en.wikipedia.org/wiki/Femoral_arteryhttp://en.wikipedia.org/wiki/Radial_arteryhttp://en.wikipedia.org/wiki/Pulse_wave_velocityhttp://en.wikipedia.org/wiki/Continuous_Noninvasive_Arterial_Pressurehttp://en.wikipedia.org/wiki/Aneroidhttp://en.wikipedia.org/wiki/Aneroidhttp://en.wikipedia.org/wiki/Armhttp://en.wikipedia.org/wiki/Cuffhttp://en.wikipedia.org/wiki/Scipione_Riva-Roccihttp://en.wikipedia.org/wiki/Sphygmomanometerhttp://en.wikipedia.org/wiki/Stethoscopehttp://en.wikipedia.org/wiki/Emergency_medical_servicehttp://en.wikipedia.org/wiki/Palpation -
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7.monitoring of body temperature:
Fever:
Infection(pneumonia)
Medication,AB Trauma
Injurey
Heat attack
Burns
Arthritis
Cancer
Hyperthyroidism
Silicosis
SunburnHypothermia:
Cold exposure
Shock
Alcohol
Drugs
Diabetes
Hypothyroidism
SepsisSites of measurements:
Oral cavity (accurate)
Armpit (inaccurate)
Rectal (most accurate)
Axilla
Esophagus
Urinary bladder
Temporal artery
Vagina Ear
Measurements devices:
Mercury thermometer
Digital
infrared
37.0 C (98.6 F)- Normal internal body temperature (which variesbetween about 36.1237.5 C (97.0299.5 F))
35 C (95 F)- (Hypothermiais less than 35 C (95 F)) - Intense shivering,
numbness and bluish/grayness of the skin.
32 C (90 F)- (Medical emergency) Hallucinations, delirium, complete
confusion, extreme sleepiness that is progressively becoming comatose.
39 C (102 F)- (Pyrexia) - Severe sweating, flushed and very red. Fast
heart rate and breathlessness.
41 C (106 F)- (Medical emergency) - Fainting, vomiting, severe
headache, dizziness, confusion, hallucinations, delirium and drowsiness can
occur.
More info about body temperature regulation:
Video 1:http://www.youtube.com/watch?v=ZywM3DN-eo0
Video 2:http://www.youtube.com/watch?v=DrdRIwD2v5g
http://en.wikipedia.org/wiki/Hypothermiahttp://en.wikipedia.org/wiki/Hypothermiahttp://en.wikipedia.org/wiki/Hypothermiahttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Pyrexiahttp://en.wikipedia.org/wiki/Pyrexiahttp://en.wikipedia.org/wiki/Pyrexiahttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Medical_emergencyhttp://www.youtube.com/watch?v=ZywM3DN-eo0http://www.youtube.com/watch?v=ZywM3DN-eo0http://www.youtube.com/watch?v=ZywM3DN-eo0http://www.youtube.com/watch?v=DrdRIwD2v5ghttp://www.youtube.com/watch?v=DrdRIwD2v5ghttp://www.youtube.com/watch?v=DrdRIwD2v5ghttp://www.youtube.com/watch?v=DrdRIwD2v5ghttp://www.youtube.com/watch?v=ZywM3DN-eo0http://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Pyrexiahttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Hypothermia -
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8.Normal salineindications, advantages, adverse effects.
Indication:
Iv.infusion (in hypovolemia,no
fluid intake) Contact lense solution
Nasal irrigation
Clean piercing
Flushwounds + skin abrasions
Combined with dextroseglucose
Source of water and electrolytesAdverse effect:
Infection Thrombosis
Phlebitis
Hypervolemia Metabolic acidosis
Interstitial edemaAdvantages:
Easy and available
Reduce risk
CheapContraindication:
Hypertension
Pulmonary edema
Dose: 1.5-3 liter/day
0.9% Sodium Chloride Solution = 9 g/L
Isotonic crystalloid solution
The pH is 5.0 (4.5 to 7.0).
osmolarity = 308 mOsmol/L.
contains 154 mEq/L Sodium and Chloride.
If used to replenish fluids, a large bore IV (18G or more) should be started,hung with a 1000 mL bag of saline.
should be used with great care, if at all, in patients with congestive heartfailure, severe renal insufficiency and in clinical states in which there exists
edema with sodium retention.
check BP and lung sounds every 250cc. Discontinue bolus if pulmonaryedema is discovered, or once BP is in therapeutic range (generally SBP above90 mm/Hg). Avoid hypervolemia.
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9. Ringer lactate solution indications, advantages, adverse
effects:Indication:
in blood loss
trauma surgery
burn
to prevent acidosis
supply water andelectrolytes (e.g.,calcium, potassium, sodium,
chloride)
contraindication:
severe metabolic acidosis
alkalosis
and in severe liver disease anoxic states which affect
lactate metabolism.Adverse effect:
Edema
Infection
Thrombosis
Phlebitis
Hypervolemia
Arrhythmia
pH: 6.2 (6.07.5)
Osmolarity: 275 mOsmol/liter
intravenous administration orsubcutaneously.
Dose: 20-30 ml/kg/hr
Na = 130mmol/L,Cl = 109 ,lactate = 28, K = 4, Ca = 1.5 crystalloids:includesaline anddextrose solutions
This solution should be used with care in patients with hypervolemia, renalinsufficiency, urinary tract obstruction, or impending or frank cardiac
decompensation.
http://www.medicinenet.com/electrolytes/article.htmhttp://en.wikipedia.org/wiki/Intravenous_therapyhttp://en.wikipedia.org/wiki/Subcutaneoushttp://en.wikipedia.org/wiki/Molarity#Molarityhttp://en.wikipedia.org/wiki/Volume_expander#Crystalloidshttp://en.wikipedia.org/wiki/Saline_(medicine)http://en.wikipedia.org/wiki/Intravenous_sugar_solutionhttp://en.wikipedia.org/wiki/Intravenous_sugar_solutionhttp://en.wikipedia.org/wiki/Saline_(medicine)http://en.wikipedia.org/wiki/Volume_expander#Crystalloidshttp://en.wikipedia.org/wiki/Molarity#Molarityhttp://en.wikipedia.org/wiki/Subcutaneoushttp://en.wikipedia.org/wiki/Intravenous_therapyhttp://www.medicinenet.com/electrolytes/article.htm -
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10.Water balance: the ratio between the water assimilated into the body and that lost from the body
more info and video:
video 1:http://www.youtube.com/watch?v=mp_3CIUqFU8video 2:http://www.youtube.com/watch?v=QDkLc1GV7Cg
video 3:http://www.youtube.com/watch?v=11a1fXbTf7g
http://www.youtube.com/watch?v=mp_3CIUqFU8http://www.youtube.com/watch?v=mp_3CIUqFU8http://www.youtube.com/watch?v=QDkLc1GV7Cghttp://www.youtube.com/watch?v=QDkLc1GV7Cghttp://www.youtube.com/watch?v=QDkLc1GV7Cghttp://www.youtube.com/watch?v=11a1fXbTf7ghttp://www.youtube.com/watch?v=11a1fXbTf7ghttp://www.youtube.com/watch?v=11a1fXbTf7ghttp://www.youtube.com/watch?v=11a1fXbTf7ghttp://www.youtube.com/watch?v=QDkLc1GV7Cghttp://www.youtube.com/watch?v=mp_3CIUqFU8 -
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11.Macromolecular solutionsindications, advantages,adverse effects, examples.
Colloid solution
Dextrans: dextran 70, dextran 40Gelatins: Gelofusin, Haemacel, Eufusin
Human albumin 5%, 20%
dimensions between 2 to 1000 nanometers.
Indication:
Hypovolemia
Shock
Spinal anesthesia(prevent hypotension)
Plasma exchange Preoperative/postoperative
Hypoalbuminemia
Prophylaxis (v.thrombosis op)Advantages:
Good volume replacement
Large duration of intravasculat remanence (wtf!!)Disadvantages:
Expensive
Risk of anaphylactic reaction Determine coagulation disorders
Nausea, vomiting
Headache
Interfere with blood groupsdetermination!!
TachycardiaContraindication:
Renal failureCongestive heart failure
(maybe!!)
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12.Dopaminemechanism of action, indications, adverse effects.
Mechanism of action:
5-10 g/kg/min sympathikus:
Heart muscle contraction
heart rate
cardiac output
blood pressure
10-20 g/kg/min Vasoconstriction BP
Vasopressor + Inotropic
Indication:
Hypotension
Bradycardia
Cardiac arrest
Shock (cardiogenic shock)
Heart failureAdverse effect:
Chest pain
Difficult urination
Weakness
Nausea , vomiting
Headache
Difficult breathing
Angina
Irregular heartbeat
azotemia
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13.Dobutaminemechanism of action, indications, adverse effects.
Dose:Continuous infusion: 2.5-15 mcg/kg/min IV
0.5-1 initially, then 2-20 not to exceed 40 mcg/kg/min
Mechanism of action:
Stimulation of 1-receptors (sympathikus):
+ inotropic
contractility
cardiac output
Indication: Heart failure ( R + L ) increase the stroke volume
Cardiogenic shock
Septic shock
Congestive heart failure ( cardiac output )
During heart surgery
Adverse effect:
Hypertension Arrhythmia
Angina
Tachycardia
Palpitation
O2-consumption
http://opencalc%28%27/calculator/dosing/iv-drip-dosing','Low%20Cardiac%20Output','Adult','Continuous%20infusion:%202.5-15%20mcg/kg/min%20IV');http://opencalc%28%27/calculator/dosing/iv-drip-dosing','Low%20Cardiac%20Output','Adult','Continuous%20infusion:%202.5-15%20mcg/kg/min%20IV'); -
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14. Adrenalinemechanism of action, indications, adverse effects.
Mechanism of action:stimulate 1,1,2 adrenergic receptor:
Relaxation of bronchial smooth muscleCardiac stimulation, HR
Dilation in skeletal muscle
Lung: respiratory rate
Liver: glycogenolysis
Muscle: glycolysis
Dose:1mg every 3-5 min (I.V or intratracheal)
Indication:
Cardiac arrest Anaphylaxis
Bronchospasm
Hypoglycemia
Asthma
Hypotension
Bradycardia
Anaphylactic shock
Glaucoma
Hemostatic In local anesthesia
Adverse effect:
Tachycardia
Palpitation
Arrhythmia
Anxiety
Panic attack
Hypertension
Pulmonary edema Angina pain
Contraindication:
Hyperthyroidism
Ischemic heart disease
Angle-closure glaucoma
Hypertension
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15. Noradrenalinemechanism of action, indications, adverse effects.
Mechanism of action:
: constrictor of blood vessel, BP, Bloodflow high Dose
: Heart (dilate coronary artery) ,inotropic +Small Doseindication:
with local anesthesia
septic shock (for refractory hypotension)
anaphylactic shock
hemostaticadverse effect:
bradycardia
headache
hypertension
diarrhea
dizziness
bleeding
dry skindose:
(initial): 8 to 12 mcg/min -titrate to BP. Usual maintenance: 2 to 4 mcg/min.
doses as high as 0.5 to 1.5 mcg/kg/min for 1-10days have been used inseptic shock.
Calculation of drip rate 8 mg/ 250 ml (ml/hr) = mcg/min x 1.875.Administer through a central line (large vein).
more info:http://www.medsafe.govt.nz/profs/datasheet/n/noradrenalineinf.pdf
http://www.medsafe.govt.nz/profs/datasheet/n/noradrenalineinf.pdfhttp://www.medsafe.govt.nz/profs/datasheet/n/noradrenalineinf.pdfhttp://www.medsafe.govt.nz/profs/datasheet/n/noradrenalineinf.pdfhttp://www.medsafe.govt.nz/profs/datasheet/n/noradrenalineinf.pdf -
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Clinical case: Respiratory failure
ARDS
Acute renal failure
Chronic renal failure
Hypovolemic shock
Cardiogenic shock
Septic shock
Anaphylactic shock
Tachycardia, Bradycardia
Acid-base-disturbances
Acidosis: respiratory + metabolic Alcalosis: respiratory + metabolic
Electrolyte disturbances
Hypernatremia
Hyponatremia
Hyperkalemia
Hypokalemia
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Laboratory Test Normal Range in USUnits
Normal Range in SIUnits
ToConvertUS to SIUnits
ALT (Alanineaminotransferase)
W 7-30 units/literM 10-55 units/liter
W 0.12-0.50 kat/literM 0.17-0.92 kat/liter
x 0.01667
Albumin 3.1 - 4.3 g/dl 31 - 43 g/liter x 10
AlkalinePhosphatase W 30-100 units/literM 45-115 units/liter W 0.5-1.67 kat/literW 0.75-1.92 kat/liter x 0.01667
Amylase (serum) 53-123 units/liter 0.88-2.05 nkat/liter x 0.01667
AST (Aspartateaminotransferase)
W 9-25 units/literM 10-40 units/liter
W 0.15-0.42 kat/literM 0.17-0.67 kat/liter
x 0.01667
Basophils 0-3% of lymphocytes 0.0-0.3 fraction of whiteblood cells
x 0.01
Bilirubin - Direct 0.0-0.4 mg/dl 0-7 mol/liter x 17.1
Bilirubin - Total 0.0-1.0 mg/dl 0-17 mol/liter x 17.1
Blood pressure Normal: 120/70 to 120/80 millimeters of mercury(mmHg). The top number is systolic pressure,
when the heart is pumping. Bottom number isdiastolic pressure then the heart is at rest. Bloodpressure can be too low (hypotension) or too high(hypertension).
Noconversion
C peptide 0.5-2.0 ng/ml 0.17-0.66 nmol/liter x 0.33
Calcium, serum 8.5 -10.5 mg/dl 2.1-2.6 mmol/liter x 0.25
Calcium, urine 0-300 mg/24h 0.0-7.5 mmol/24h x 0.025
Cholesterol, totalDesirableMarginalHigh
239 mg/dL6.18 mmol/liter
x 0.02586
Cholesterol, LDLDesirableMarginal
HighVery High
190 mg/dL 4.91 mmol/literx 0.02586
Cholesterol, HDLDesirable >60 mg/dL >1.55 mmol/liter
x 0.02586
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ModerateLow (heart risk)
40-60 mg/dL 1.03-1.55 mmol/liter
Cortisol: serum 0-25 g/dl (depends ontime of day)
0-690 nmol/liter x 27.59
Cortisol: free
(urine)
20-70 g/dl 55-193 nmol/24h x 2.759
Creatine kinase W 40-150 units/liter
M 60-400 units/liter
W 0.67-2.50 kat/liter
M 1.00-6.67 kat/liter
x 0.01667
DHEA W 130-980 ng/dlM 180-1250 ng/dl
W 4.5-34.0 nmol/literM 6.24-43.3 nmol/liter
x 0.03467
DHEASulfate W Pre-menopause: 12-535 g/dlW Post-menopause: 30-260 g/dlM 10-619 g/dl
W Pre-menopause: 120-5350 g/literW Post-menopause: 300-2600 g/literM 100-6190 g/liter
x 10
Eosinophils 0-8% of white blood cells 0.0-0.8 fraction of white
blood cells
x 0.01
Erythrocytesedimentationrate (Sed Rate)
W M W M Noconversion
Folate 3.1-17.5 ng/ml 7.0-39.7 nmol/liter x 2.266
Glucose, urine x 0.05551
Glucose, plasma 70-110 mg/dl 3.9-6.1 mmol/liter x 0.05551
GGT (Gammaglutamyltransferase)
W M W M Noconversion
Hematocrit W 36.0% - 46.0% of red
blood cellsM 37.0% - 49.0% of redblood cells
W 0.36-0.46 fraction of
red blood cellsM 0.37-0.49 fraction ofred blood cells
x 0.01
Hemoglobin W 12.0-16.0 g/dlM 13.0-18.0 g/dl
W 7.4-9.9 mmol/literM 8.1-11.2 mmol/liter
x 0.6206
LDH (Lactatedehydrogenase)(total)
x0.016667
Lactic acid 0.5-2.2 mmol/liter 0.5-2.2 mmol/liter Noconversion
Leukocytes (WBC) 4.5-11.0x103/mm3 4.5-11.0x109/liter No
conversionLymphocytes 16%-46% of white blood
cells0.16-0.46 fraction ofwhite blood cells
x 0.01
Mean corpuscularhemoglobin(MCH)
25.0-35.0 pg/cell 25.0-35.0 pg/cell Noconversion
Mean corpuscularhemoglobin
31.0-37.0 g/dl 310-370 g/liter x 10
http://www.thebody.com/content/art6029.html?ic=4001http://www.thebody.com/content/art6029.html?ic=4001http://www.thebody.com/content/art6029.html?ic=4001 -
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concentration(MCHC)
MCV (Meancorpuscularvolume)
W 78-102 m3M 78-100 m3
W 78-102 flM 78-100 fl
Noconversion
Monocytes 4-11% of white bloodcells 0.04-0.11 fraction ofwhite blood cells x 0.01
Neutrophils 45%-75% of white bloodcells
0.45-0.75 fraction ofwhite blood cells
x 0.01
Phosphorus 2.5 4.5 mg/dL 0.81-1.45 mmol/L x 0.323
Platelets(Thrombocytes)
130 400 x 10 3L 130 400 x 10 9L Noconversion
Potassium 3.4-5.0 mmol/liter 3.4-5.0 mmol/liter Noconversion
RBC (Red bloodcell count)
W 3.9 5.2 x 106/L3M 4.4 5.8 x 10 6/L3
W 3.9 5.2 x 1012/LM 4.4 5.8 x 10 12/L
Noconversion
Sodium 135-145 mmol/liter 135-145 mmol/liter Noconversion
Testosterone,total (morningsample)
W 6-86 ng/dlM 270-1070 ng/dl
W 0.21-2.98 nmol/literM 9.36-37.10 nmol/liter
x 0.03467
Testosterone, freeAge 20-40
Age 41-60
Age 61-80
W 0.6-3.1,M 15.0-40.0 pg/mlW 0.4-2.5,M 13.0-35.0 pg/ml
W 0.2-2.0,M 12.0-28.0 pg/ml
W 20.8-107.5,M 520-1387 pmol/literW 13.9-86.7,M 451-1213 pmol/liter
W 6.9-69.3,M 416-971 pmol/liter
x 34.67
Triglicerides(fasting)NormalBorderlineHighVery high
40-150 mg/dl150-200 mg/dl200-500 mg/dl>500 mg/dl
0.45-1.69 mmol/liter1.69-2.26 mmol/liter2.26-5.65 mmol/liter>5.65 mmol/liter
x 0.01129
Urea, plasma(BUN)
8-25 mg/dl 2.9-8.9 mmol/liter x 0.357
Urinalysis - pHSpecific gravity 5.0-9.01.001-1.035 5.0-9.01.001-1.035 Noconversion
WBC (White bloodcells, leukocytes)
4.5-11.0x10 3/mm 3 4.5-11.0x10 9liter Noconversion