ati khaled khalilia

Upload: khaled-khalilia

Post on 01-Jun-2018

222 views

Category:

Documents


0 download

TRANSCRIPT

  • 8/9/2019 ATI Khaled khalilia

    1/39

    Khaled khalilia 1

    ATISUBJECTS FOR THE PRACTICAL EXAMINATION

    ANESTHESIA AND INTENSIVE CARE

    MEDICINE 4TH

    YEAR

    Khaled khalilia

    4th

    year

  • 8/9/2019 ATI Khaled khalilia

    2/39

    Khaled khalilia 2

    SUBJECTS FOR THE PRACTICAL EXAMINATION

    ANESTHESIA AND INTENSIVE CARE

    MEDICINE 4TH

    YEAR

    1.1The technique of chest compression.

    1.2Desobstruction of the upper respiratory airway in case of liquid foreign bodies.

    1.3Desobstruction of the upper respiratory airway in case of solid foreign bodies.

    1.4Maneuvers of upper respiratory airway opening in a patient without suspicion of

    cervical spine lesion.

    1.5Maneuvers of upper respiratory airway opening the upper respiratory airway in

    a patient with suspicion of cervical spine lesion.

    1.6Evaluation of spontaneous breathing.

    1.7Pulse evaluation.

    1.8The technique ofmouth to mouth artificial respiration.

    1.9Recovery position.

    1.10 Defibrillation technique.

    2.1 Peripheral venous accessindications, technique, advantages, disadvantages.2.2 Central venous accessindications, technique, advantages, disadvantages.

    2.3 Arterial catheterindications, technique, advantages, disadvantages.2.4 Oxygen therapyindications, administration systems, adverse effects.

    2.5 Pulse oximetry.2.6 Monitorization of arterial blood pressure.

    2.7 Monitorization of body temperature.

    2.8 Normal salineindications, advantages, adverse effects.2.9 Ringer lactate solutionindications, advantages, adverse effects.

    2.10 Water balance.

    2.11 Macromolecular solutions indications, advantages, adverse effects,examples.

    2.12 Dopaminemechanism of action, indications, adverse effects.2.13 Dobutaminemechanism of action, indications, adverse effects.

    2.14 Adrenalinemechanism of action, indications, adverse effects.2.15 Noradrenalinemechanism of action, indications, adverse effects.

    3. Clinical case

    Associate Professor Ioana Grigoras, MD, PhD

  • 8/9/2019 ATI Khaled khalilia

    3/39

    Khaled khalilia 3

    1.The technique of chest compression.

    Use heel of two hands placed above center of chest (superior to xiphoid). Depress chest at least 4- 5 cm

    Compression rate at least 100 times/minute

    Compress 30 times within 18 seconds

    Compression to Ventilation Ratio 30:2

    Depth: 4-6 cm

    Frequency: 100/min

    Ratio: 30:2

    Video :http://www.youtube.com/watch?v=qSsHcdy4GnA

    More iformation:http://www.resus.org.au/policy/guidelines/section_13/guideline-13-6dec10.pdf

    http://www.youtube.com/watch?v=qSsHcdy4GnAhttp://www.youtube.com/watch?v=qSsHcdy4GnAhttp://www.youtube.com/watch?v=qSsHcdy4GnAhttp://www.resus.org.au/policy/guidelines/section_13/guideline-13-6dec10.pdfhttp://www.resus.org.au/policy/guidelines/section_13/guideline-13-6dec10.pdfhttp://www.resus.org.au/policy/guidelines/section_13/guideline-13-6dec10.pdfhttp://www.resus.org.au/policy/guidelines/section_13/guideline-13-6dec10.pdfhttp://www.youtube.com/watch?v=qSsHcdy4GnA
  • 8/9/2019 ATI Khaled khalilia

    4/39

    Khaled khalilia 4

    2.Desobstruction of the upper respiratory airway in case

    of liquid foreign bodies.

    Look, listen,feel, ABCDE Abdominal movements, airflow via mouth and nose

    Oropharyngeal tube: coma patient

    Nasophyryngeal tube.

    Tracheal intubation

    The Yankauer suctionis anoralsuctioningtool used in medicalprocedures.This tool is used to suctionoropharyngealsecretions in

    order to prevent. Remove the liquid,saliva.

    Video: yankauer suction:http://www.youtube.com/watch?v=CQ2TN3njTJg

    http://en.wikipedia.org/wiki/Mouthhttp://en.wikipedia.org/wiki/Mouthhttp://en.wikipedia.org/wiki/Suction_(medicine)http://en.wikipedia.org/wiki/Suction_(medicine)http://en.wikipedia.org/wiki/Suction_(medicine)http://en.wikipedia.org/wiki/Human_pharynxhttp://en.wikipedia.org/wiki/Human_pharynxhttp://en.wikipedia.org/wiki/Human_pharynxhttp://www.youtube.com/watch?v=CQ2TN3njTJghttp://www.youtube.com/watch?v=CQ2TN3njTJghttp://www.youtube.com/watch?v=CQ2TN3njTJghttp://www.youtube.com/watch?v=CQ2TN3njTJghttp://en.wikipedia.org/wiki/Human_pharynxhttp://en.wikipedia.org/wiki/Suction_(medicine)http://en.wikipedia.org/wiki/Mouth
  • 8/9/2019 ATI Khaled khalilia

    5/39

    Khaled khalilia 5

    3.Desobstruction of the upper respiratory airway in case

    of solid foreign bodies. ( i dunno exactly)

    Traumatic causes

    Laryngeal stenosis Airway burn Acute laryngeal injury

    Facial trauma (mandibular or maxillary

    fractures)

    Hemorrhage

    Infections Suppurative parotitis

    Retropharyngeal abscess Tonsillar hypertrophy

    Ludwigs angina

    Epiglottitis Laryngitis

    Laryngotracheobronchitis (croup)

    Iatrogenic causes

    Tracheal stenosis post-tracheostomy Tracheal stenosis post-intubation Mucous ball from transtracheal catheter

    Foreign bodies

    Vocal cord paralysis

    Tumors Laryngeal tumors (benign or malignant)

    Laryngeal papillomatosis

    TrachealAngioedema

    Anaphylactic reactions

    C1 inhibitor deficiency Angiotensin-converting enzyme inhibitors

    A foreign body may become lodged in the larynx, trachea, or bronchus. The rightbronchus is more commonly affected than the left because of the lesser angle ofdivergence relative to the left bronchus and because of its greater diameter.7,10 Largerforeign bodies may become lodged in the larynx. Laryngotracheal foreign bodies areassociated with increased morbidity and mortality.1

    Signs and symptoms associated with foreign body aspiration occur in 3 phases.

    Stage 1.Choking, coughing, gasping, and respiratory distress develop because ofairway obstruction. Choking lasts for a few seconds to several minutes after the episodeand may be self-limited.

    Stage 2.Acute symptoms may be followed by a temporary quiescent phase in which thepatient may not have any symptoms.

    Stage 3.During the last phase, symptoms of complications such as infection maydevelop.

    A foreign body that completely obstructs the upper airway is an immediate threatto life and must be removed immediately.

    The head-down back-blow maneuver, the first step recommended for infants,combines the force of gravity with the force the chest compression generates toexpel intrathoracic air.

    Heimnlich maneuver

    cricothyroidoctomy

  • 8/9/2019 ATI Khaled khalilia

    6/39

    Khaled khalilia 6

    4.Maneuvers of upper respiratory airway opening in a

    patient without suspicion of cervical spine lesion.

    Safe position Head extension

    Chin lift

    Head lift

    Jaw thrust

    Mouth opening

    Head extension Finger sweep maneuver, remove forign body.

    In order to have a better view :

    Video 1:http://www.youtube.com/watch?v=etPa9oxVWyUVideo 2:http://www.youtube.com/watch?v=2fnS8mtqzms

    Video 3:http://www.youtube.com/watch?v=oTHe8qKoMqo

    Video 4:http://www.youtube.com/watch?v=BuXV2ubmf20

    http://www.youtube.com/watch?v=etPa9oxVWyUhttp://www.youtube.com/watch?v=etPa9oxVWyUhttp://www.youtube.com/watch?v=etPa9oxVWyUhttp://www.youtube.com/watch?v=2fnS8mtqzmshttp://www.youtube.com/watch?v=2fnS8mtqzmshttp://www.youtube.com/watch?v=2fnS8mtqzmshttp://www.youtube.com/watch?v=oTHe8qKoMqohttp://www.youtube.com/watch?v=oTHe8qKoMqohttp://www.youtube.com/watch?v=oTHe8qKoMqohttp://www.youtube.com/watch?v=BuXV2ubmf20http://www.youtube.com/watch?v=BuXV2ubmf20http://www.youtube.com/watch?v=BuXV2ubmf20http://www.youtube.com/watch?v=BuXV2ubmf20http://www.youtube.com/watch?v=oTHe8qKoMqohttp://www.youtube.com/watch?v=2fnS8mtqzmshttp://www.youtube.com/watch?v=etPa9oxVWyU
  • 8/9/2019 ATI Khaled khalilia

    7/39

    Khaled khalilia 7

    5.Maneuvers of upper respiratory airway opening theupper respiratory airway in a patient with suspicion of

    cervical spine lesion.

    See the video:http://www.youtube.com/watch?v=DJY89_jC_ZYMore information:http://www.primary-surgery.org/ps/vol2/html/sect0226.html

    http://www.youtube.com/watch?v=DJY89_jC_ZYhttp://www.youtube.com/watch?v=DJY89_jC_ZYhttp://www.youtube.com/watch?v=DJY89_jC_ZYhttp://www.primary-surgery.org/ps/vol2/html/sect0226.htmlhttp://www.primary-surgery.org/ps/vol2/html/sect0226.htmlhttp://www.primary-surgery.org/ps/vol2/html/sect0226.htmlhttp://www.primary-surgery.org/ps/vol2/html/sect0226.htmlhttp://www.youtube.com/watch?v=DJY89_jC_ZY
  • 8/9/2019 ATI Khaled khalilia

    8/39

    Khaled khalilia 8

    6.Evaluation of spontaneous breathing.

    ABCDE Tension pneumothorax: needle thoracostomy folowed by drainage

    Flail chest:ventilitation and stabilization and dressing

    Hemothorax: intercostal drain insertion

    Pneumothorax:intercostal drain insertion Open pneumothorax: Thoracostomy tube

    Pericardial temponade: pericardiocenthesis

    Check the following: Look,listen,feel

    Lung

    Chest wall

    Diaphragm

    Chest movements

    Auscultation Percusion

    Airway potency and breathing

    .

  • 8/9/2019 ATI Khaled khalilia

    9/39

    Khaled khalilia 9

    7.Pulse evaluation.? (from wikipedia )

    Rate:Normal pulse ratesat rest,in beats per minute (BPM)

    Children (1-10 years): 70-130Children over 10 years and adults: 60-100

    Athletes: 40-60

    Rythem: A normal pulse is regular in rhythm and force. Anirregular pulse may be due tosinus arrhythmia,premature

    beats,ectopic beats,atrial fibrillation,paroxysmal atrial

    tachycardia,atrial flutter,partial heart block etc.

    Volume: The degree of expansion displayed by artery duringdiastolic and systolic state is called volume. It also known as

    amplitude, expansion or size of pulse.

    Hypokinetic pulse:A weak pulse signifies narrowpulse pressure.It may be due to lowcardiac output (as seen inshock,congestive

    cardiac failure),hypovolemia,valvular heart disease (such asaortic

    outflow tract obstruction,mitral stenosis,aortic arch syndrome)etc

    Hyperkinetic pulse: A bounding pulse signifies high pulsepressure. It may be due to lowperipheral resistance (as seen

    infever,anemia,thyrotoxicosis,hyperkinetic heart syndrome,A-V

    fistula,Paget's diseaseberiberi,liver cirrhosis), increased cardiac

    output, increasedstroke volume (as seen in anxiety,

    exercise,complete heart block,aortic regurgitation), decreased

    distensibility of arterial system (as seen

    inatherosclerosis,hypertension andcoarctation of aorta).

    http://en.wikipedia.org/wiki/Heart_rate#At_resthttp://en.wikipedia.org/wiki/Sinus_arrhythmiahttp://en.wikipedia.org/w/index.php?title=Premature_beats&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Premature_beats&action=edit&redlink=1http://en.wikipedia.org/wiki/Ectopic_beatshttp://en.wikipedia.org/wiki/Atrial_fibrillationhttp://en.wikipedia.org/w/index.php?title=Paroxysmal_atrial_tachycardia&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Paroxysmal_atrial_tachycardia&action=edit&redlink=1http://en.wikipedia.org/wiki/Atrial_flutterhttp://en.wikipedia.org/w/index.php?title=Partial_heart_block&action=edit&redlink=1http://en.wikipedia.org/wiki/Pulse_pressurehttp://en.wikipedia.org/wiki/Cardiac_outputhttp://en.wikipedia.org/wiki/Shock_(circulatory)http://en.wikipedia.org/wiki/Congestive_cardiac_failurehttp://en.wikipedia.org/wiki/Congestive_cardiac_failurehttp://en.wikipedia.org/wiki/Hypovolemiahttp://en.wikipedia.org/wiki/Valvular_heart_diseasehttp://en.wikipedia.org/w/index.php?title=Aortic_outflow_tract_obstruction&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Aortic_outflow_tract_obstruction&action=edit&redlink=1http://en.wikipedia.org/wiki/Mitral_stenosishttp://en.wikipedia.org/wiki/Aortic_arch_syndromehttp://en.wikipedia.org/wiki/Peripheral_resistancehttp://en.wikipedia.org/wiki/Feverhttp://en.wikipedia.org/wiki/Anemiahttp://en.wikipedia.org/wiki/Thyrotoxicosishttp://en.wikipedia.org/w/index.php?title=Hyperkinetic_heart_syndrome&action=edit&redlink=1http://en.wikipedia.org/wiki/Arteriovenous_fistulahttp://en.wikipedia.org/wiki/Arteriovenous_fistulahttp://en.wikipedia.org/wiki/Paget%27s_diseasehttp://en.wikipedia.org/wiki/Liver_cirrhosishttp://en.wikipedia.org/wiki/Stroke_volumehttp://en.wikipedia.org/wiki/Complete_heart_blockhttp://en.wikipedia.org/wiki/Aortic_regurgitationhttp://en.wikipedia.org/wiki/Atherosclerosishttp://en.wikipedia.org/wiki/Hypertensionhttp://en.wikipedia.org/wiki/Coarctation_of_aortahttp://en.wikipedia.org/wiki/Coarctation_of_aortahttp://en.wikipedia.org/wiki/Hypertensionhttp://en.wikipedia.org/wiki/Atherosclerosishttp://en.wikipedia.org/wiki/Aortic_regurgitationhttp://en.wikipedia.org/wiki/Complete_heart_blockhttp://en.wikipedia.org/wiki/Stroke_volumehttp://en.wikipedia.org/wiki/Liver_cirrhosishttp://en.wikipedia.org/wiki/Paget%27s_diseasehttp://en.wikipedia.org/wiki/Paget%27s_diseasehttp://en.wikipedia.org/wiki/Arteriovenous_fistulahttp://en.wikipedia.org/wiki/Arteriovenous_fistulahttp://en.wikipedia.org/w/index.php?title=Hyperkinetic_heart_syndrome&action=edit&redlink=1http://en.wikipedia.org/wiki/Thyrotoxicosishttp://en.wikipedia.org/wiki/Anemiahttp://en.wikipedia.org/wiki/Feverhttp://en.wikipedia.org/wiki/Peripheral_resistancehttp://en.wikipedia.org/wiki/Aortic_arch_syndromehttp://en.wikipedia.org/wiki/Mitral_stenosishttp://en.wikipedia.org/w/index.php?title=Aortic_outflow_tract_obstruction&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Aortic_outflow_tract_obstruction&action=edit&redlink=1http://en.wikipedia.org/wiki/Valvular_heart_diseasehttp://en.wikipedia.org/wiki/Hypovolemiahttp://en.wikipedia.org/wiki/Congestive_cardiac_failurehttp://en.wikipedia.org/wiki/Congestive_cardiac_failurehttp://en.wikipedia.org/wiki/Shock_(circulatory)http://en.wikipedia.org/wiki/Cardiac_outputhttp://en.wikipedia.org/wiki/Pulse_pressurehttp://en.wikipedia.org/w/index.php?title=Partial_heart_block&action=edit&redlink=1http://en.wikipedia.org/wiki/Atrial_flutterhttp://en.wikipedia.org/w/index.php?title=Paroxysmal_atrial_tachycardia&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Paroxysmal_atrial_tachycardia&action=edit&redlink=1http://en.wikipedia.org/wiki/Atrial_fibrillationhttp://en.wikipedia.org/wiki/Ectopic_beatshttp://en.wikipedia.org/w/index.php?title=Premature_beats&action=edit&redlink=1http://en.wikipedia.org/w/index.php?title=Premature_beats&action=edit&redlink=1http://en.wikipedia.org/wiki/Sinus_arrhythmiahttp://en.wikipedia.org/wiki/Heart_rate#At_rest
  • 8/9/2019 ATI Khaled khalilia

    10/39

    Khaled khalilia

    10

    8.The technique ofmouthto mouth artificial respiration.

    Assume thatPatient has pulse and CPR is not necessary!!!Resuscitation by inducing artificial respiration consists of two actions:

    (1) establishing and maintaining an open air passage from the upperrespiratory tract (mouth,throat, andpharynx)to thenlungs .

    (2) exchanging air andcarbon dioxide in the terminal air sacs of the lungswhile theheart is still functioning.

    Safe position

    Head tilt

    Chin lift Jaw thrust

    Mouth opening

    While keeping the head tilted, seal the victims mouth with your mouthand seal the patients nose with your fingers. Blow air into the mouthfor at least 1 second. You must give two blows initially.

    Another thing to consider in providing mouth to mouth in infants.

    Considering that they are small, there is no need to pinch the nose.The nose can be sealed by including it in your blows as you blow onthe infants mouth. Make sure also not to put to much air as you blowon infants. Only use the air from your mouth and not from yourdiapraghm.

    Video:http://www.youtube.com/watch?v=Lbh7g-m_bwQ

    http://www.britannica.com/EBchecked/topic/499856/resuscitationhttp://www.britannica.com/EBchecked/topic/395124/mouthhttp://www.britannica.com/EBchecked/topic/455238/pharynxhttp://www.britannica.com/EBchecked/topic/351473/lunghttp://www.britannica.com/EBchecked/topic/94900/carbon-dioxidehttp://www.britannica.com/EBchecked/topic/258344/hearthttp://www.youtube.com/watch?v=Lbh7g-m_bwQhttp://www.youtube.com/watch?v=Lbh7g-m_bwQhttp://www.britannica.com/EBchecked/topic/258344/hearthttp://www.britannica.com/EBchecked/topic/94900/carbon-dioxidehttp://www.britannica.com/EBchecked/topic/351473/lunghttp://www.britannica.com/EBchecked/topic/455238/pharynxhttp://www.britannica.com/EBchecked/topic/395124/mouthhttp://www.britannica.com/EBchecked/topic/499856/resuscitation
  • 8/9/2019 ATI Khaled khalilia

    11/39

    Khaled khalilia

    11

    9.Recovery position.

    1. Kneel next to the person. Place

    the arm closest to you straight outfrom the body. Position the far

    arm with the back of the handagainst the near cheek.

    2. Grab and bend the person's far

    knee.

    3. Protecting the head with onehand, gently roll the person

    toward you by pulling the far kneeover and to the ground.

    4. Tilt the head up slightly so that

    the airway is open. Make sure thatthe hand is under the cheek. Place

    a blanket or coat over the person(unless he or she has a heat illness

    or fever) and stay close until helparrives.

    Infant Recovery Position

    Place the infant face down over your arm with the head slightly lower than

    the body. Support the head and neck with your hand, keeping the mouth andnose clear. Wait for help to arrive.

  • 8/9/2019 ATI Khaled khalilia

    12/39

    Khaled khalilia

    12

    10. Defibrillation technique : check the script for moreinfo

  • 8/9/2019 ATI Khaled khalilia

    13/39

    Khaled khalilia

    13

    1. Peripheral venous accessindications, technique, advantages,

    disadvantages.

    Indication:

    Emergency

    Operation

    Radiology

    Hydration

    Nutritional

    Medication

    Cardiac arrest

    Blood products

    Long term AB-therapy

    Complication:

    Infection

    Phlebitis

    Bleeding

    Air embolism

    infiltration

    Advantages:

    Simple technique

    Short time (quick)

    No interruption of chestcompression

    Low costDisadvantages:

    Long time of drug circulation

    Easy to lose venous accessSites:

    Upper extremity: Cephalic vein,median cubital or Basilic vein

    Low extremity: great

    saphenus vein, MedianMarginal Vein

    Scalp: Small superficial vein

    Technique:

    A.ConsiderLocal Anesthesiaat catheter insertion site (Lidocaine)B.Consider limb warming prior to IV cannula insertionC.Immobilize the extremityD.stretch the vein Flex the wrist to extend the dorsal hand veinsE.Apply aTourniquetto proximal veinF.Antiseptic to cannulation siteG.Flush the needle catheter with sterile saline

    H.Enter Skin1. Puncture distal to the site2. Enter at 45 degrees with bevel down3. Pull the skin to the side while entering skin4. Avoid entering the vein with needle

    I. Cannulate vein, remove the needle and the tourniquet

    http://www.fpnotebook.com/Surgery/Pharm/LclSknAnsths.htmhttp://www.fpnotebook.com/Surgery/Pharm/LclSknAnsths.htmhttp://www.fpnotebook.com/Surgery/Pharm/LclSknAnsths.htmhttp://www.fpnotebook.com/ER/Pharm/Trnqt.htmhttp://www.fpnotebook.com/ER/Pharm/Trnqt.htmhttp://www.fpnotebook.com/ER/Pharm/Trnqt.htmhttp://www.fpnotebook.com/ER/Pharm/Trnqt.htmhttp://www.fpnotebook.com/Surgery/Pharm/LclSknAnsths.htm
  • 8/9/2019 ATI Khaled khalilia

    14/39

    Khaled khalilia

    14

    Peripheral venous access:Video 1:http://www.youtube.com/watch?v=nVem1__qW14

    Video 2:http://www.youtube.com/watch?v=IMSMvAMHfL8

    Video 3:http://www.youtube.com/watch?v=9eHimrGgnm4

    http://www.youtube.com/watch?v=nVem1__qW14http://www.youtube.com/watch?v=nVem1__qW14http://www.youtube.com/watch?v=nVem1__qW14http://www.youtube.com/watch?v=IMSMvAMHfL8http://www.youtube.com/watch?v=IMSMvAMHfL8http://www.youtube.com/watch?v=IMSMvAMHfL8http://www.youtube.com/watch?v=9eHimrGgnm4http://www.youtube.com/watch?v=9eHimrGgnm4http://www.youtube.com/watch?v=9eHimrGgnm4http://www.youtube.com/watch?v=9eHimrGgnm4http://www.youtube.com/watch?v=IMSMvAMHfL8http://www.youtube.com/watch?v=nVem1__qW14
  • 8/9/2019 ATI Khaled khalilia

    15/39

    Khaled khalilia

    15

    2. Central venous accessindications, technique, advantages,

    disadvantages.Indication:

    Medication

    Fluids adm. Bloodtests

    Cardiovascular measurements

    Long term AB

    Long term pain medicaments

    Longterm parenteral nutrition

    Dialysis

    Plasmaphoresis

    Complication: Infection

    Phlebitis

    Bleeding

    Air embolism

    Infiltration

    Pneumothorax

    Thrombosis(DVT and vein)

    Arrhythmias

    Advantages:

    Short time of drug circulation

    Safe access Longlasting access

    Hypertonic solution

    Monitor treatment response

    Evaluate heart filling (RV)Disadvantages:

    Temporary interruption ofcardiac message

    Long installation time

    Complication rate Require special equipment

    Sites of insertion:

    Neck: internal jugular vein

    Chest: subclavian vein oraxillary vein

    Goin: femoral vein

    Non tunneled: fixed in place

    Tunneled: under the skin, monoluminal,biluminal, triluminal

    CathetherInternal jugular vein External Subclavian vein

    Axillary veinBrachial vein.

  • 8/9/2019 ATI Khaled khalilia

    16/39

    Khaled khalilia

    16

    Central vein access:

    Video 1:http://www.youtube.com/watch?v=H3mJjtTk27Q

    Video 2:http://www.youtube.com/watch?v=7YRXirk--hoVideo 3:http://www.youtube.com/watch?v=Sgypvr2fNq0

    Video 4:http://www.youtube.com/watch?v=LkPCuJKREyo

    http://www.youtube.com/watch?v=H3mJjtTk27Qhttp://www.youtube.com/watch?v=H3mJjtTk27Qhttp://www.youtube.com/watch?v=H3mJjtTk27Qhttp://www.youtube.com/watch?v=7YRXirk--hohttp://www.youtube.com/watch?v=7YRXirk--hohttp://www.youtube.com/watch?v=7YRXirk--hohttp://www.youtube.com/watch?v=Sgypvr2fNq0http://www.youtube.com/watch?v=Sgypvr2fNq0http://www.youtube.com/watch?v=Sgypvr2fNq0http://www.youtube.com/watch?v=LkPCuJKREyohttp://www.youtube.com/watch?v=LkPCuJKREyohttp://www.youtube.com/watch?v=LkPCuJKREyohttp://www.youtube.com/watch?v=LkPCuJKREyohttp://www.youtube.com/watch?v=Sgypvr2fNq0http://www.youtube.com/watch?v=7YRXirk--hohttp://www.youtube.com/watch?v=H3mJjtTk27Q
  • 8/9/2019 ATI Khaled khalilia

    17/39

    Khaled khalilia

    17

    3. Arterial catheter (arterial line) indications, technique,

    advantages, disadvantages.Indication:

    Continuous direct blood

    pressure monitoringarterial blood gas sampling

    Central venous pressure

    R.atrium pressure

    Pressure in pulmonary artery

    Cardiac output

    Stroke volume

    O2-cosumption and delivery

    Vascular resistance

    Advantages:Shock diagnosis

    Monitor treatment responseDisadvantages:

    Complication

    Required special equipment

    Complication: Infection

    Pneumothorax

    Hematoma,bleeding

    Thrombosis

    Aneurysm

    FistulaSite of insertion:

    Radial artery

    Brachial artery Femoral artery

    Ulnar artery

    Dorsalis pedis artery

    Technique:

    1. Arm is abducted and the wrist hyperextended

    2. Local skin anesthesia is then administered

    3. Proximal to styloid process of the radius, a small incision is made over the skin

    4. Subcutaneous tissue is then tunneled using forceps

    5. At 45 angle, an 18-21 guage needle should be introduced

    6. Radial sheath of 23cm long and 4-6Fr size should then be introduced

    7. Using a rotating arm board under the shoulder facilitates ease of movement and

    placement of radial sheath

    8. Through sidearm of the sheath, 5000U ofheparinshould be administered

    9. To reduce spasm, 500 micrograms ofdiltiazemcan also be administered

    10. Coronary catheters are then advanced along the guidewire into aorta

    11. Left and right coronary arteries are then catheterized using Judkins, Amplatz or

    multipurpose catheter

    http://emedicine.medscape.com/article/1902703-overviewhttp://www.wikidoc.org/index.php/Heparinhttp://www.wikidoc.org/index.php/Heparinhttp://www.wikidoc.org/index.php/Heparinhttp://www.wikidoc.org/index.php/Diltiazemhttp://www.wikidoc.org/index.php/Diltiazemhttp://www.wikidoc.org/index.php/Diltiazemhttp://www.wikidoc.org/index.php/Diltiazemhttp://www.wikidoc.org/index.php/Heparinhttp://emedicine.medscape.com/article/1902703-overview
  • 8/9/2019 ATI Khaled khalilia

    18/39

    Khaled khalilia

    18

    12. Hemostasis is achieved by direct pressure at the puncture site at the end of the

    procedure after removal of radial sheath

    13. Radial pulse should be monitored after the procedure for several hours regularly.

    Arterial cathether:More info:http://www.arrowintl.com/documents/pdf/literature/eng-sac-c0507.pdf

    Video 1:http://www.youtube.com/watch?v=CLxxM4yltwo

    Video 2:http://www.youtube.com/watch?v=6--8J4iqGEY

    Video 3:http://www.youtube.com/watch?v=qv54USEYNzw

    http://www.arrowintl.com/documents/pdf/literature/eng-sac-c0507.pdfhttp://www.arrowintl.com/documents/pdf/literature/eng-sac-c0507.pdfhttp://www.arrowintl.com/documents/pdf/literature/eng-sac-c0507.pdfhttp://www.youtube.com/watch?v=CLxxM4yltwohttp://www.youtube.com/watch?v=CLxxM4yltwohttp://www.youtube.com/watch?v=CLxxM4yltwohttp://www.youtube.com/watch?v=6--8J4iqGEYhttp://www.youtube.com/watch?v=6--8J4iqGEYhttp://www.youtube.com/watch?v=6--8J4iqGEYhttp://www.youtube.com/watch?v=qv54USEYNzwhttp://www.youtube.com/watch?v=qv54USEYNzwhttp://www.youtube.com/watch?v=qv54USEYNzwhttp://www.youtube.com/watch?v=qv54USEYNzwhttp://www.youtube.com/watch?v=6--8J4iqGEYhttp://www.youtube.com/watch?v=CLxxM4yltwohttp://www.arrowintl.com/documents/pdf/literature/eng-sac-c0507.pdf
  • 8/9/2019 ATI Khaled khalilia

    19/39

    Khaled khalilia

    19

    4. Oxygen therapy indications, administration systems,

    adverse effects.

    chronic indication:

    COPD (chronic bronchitis andemphysema)

    Breathless patient

    Endstage cardiac failure

    Endstage respiratory failure

    CancerAcute indication:

    Emergency, hospital and firstaid

    Resuscitation

    TraumaAnaphylaxis

    Hemorrhage

    Shock

    Hypothermia

    Hypoxemia

    Cluster headache

    Fire risk

    Asthma

    PneumoniaRDS

    Administration:

    Nasal canula 5L/min

    Face mask 50 %

    Venture mask

    Mask+ reservoir Bag 70%

    Mask + one way valves 80%

    Nasal canula 100%

    Very tight masksanesthesiaPocket mask

    Bag-valve-mask (cyaidepoisoning)

    Filtered o2-mask

    Storage and sources:

    Liquid and compressed gas

  • 8/9/2019 ATI Khaled khalilia

    20/39

    Khaled khalilia

    20

    Oxygen therapy:Video 1:http://www.youtube.com/watch?v=FT7t9hroLLgVideo 2:http://www.youtube.com/watch?v=Nc2zl2SeQNo

    Video 3:http://www.youtube.com/watch?v=MNzCfO7Z0Fk

    http://www.youtube.com/watch?v=FT7t9hroLLghttp://www.youtube.com/watch?v=FT7t9hroLLghttp://www.youtube.com/watch?v=FT7t9hroLLghttp://www.youtube.com/watch?v=Nc2zl2SeQNohttp://www.youtube.com/watch?v=Nc2zl2SeQNohttp://www.youtube.com/watch?v=Nc2zl2SeQNohttp://www.youtube.com/watch?v=MNzCfO7Z0Fkhttp://www.youtube.com/watch?v=MNzCfO7Z0Fkhttp://www.youtube.com/watch?v=MNzCfO7Z0Fkhttp://www.youtube.com/watch?v=MNzCfO7Z0Fkhttp://www.youtube.com/watch?v=Nc2zl2SeQNohttp://www.youtube.com/watch?v=FT7t9hroLLg
  • 8/9/2019 ATI Khaled khalilia

    21/39

    Khaled khalilia

    21

    5.Pulse oximetry:

    Pulse oximetryis anon-invasive method for monitoring a patient'sO2saturation.

    a sensor is placed on a thin part of the patient's body, usuallyafingertiporearlobe,or in the case of aninfant,across a foot.

    The principle of pulse oximetry is based on the red and infraredlight absorption characteristics of oxygenated and deoxygenated

    hemoglobin. Oxygenated hemoglobin absorbs more infrared light

    and allows more red light to pass through. Deoxygenated (or

    reduced) hemoglobin absorbs more red light and allows more

    infrared light to pass through. Red light is in the 600-750 nmwavelength light band. Infrared light is in the 850-1000 nm

    wavelength light band. (not very important !! general knowledge)

    Indication:

    Monitor o2-saturation

    Sleep disorders

    Sleep apnea

    Emergency Surgery

    COPD

    Asthma

    Pneumonia

    Congestive heart failure

    Anemia

    Lung cancer

    During anaesthesia

    Advantages: Detect arrhythmias

    Evaluation of A.bloodoxygenation

    Measure HR

    Evaluate peripheral perfusion

    Non-invasive Transportable

    Detect ventilation abnormalitiesDisadvantages:

    Movementartefacts

    Painted nailsdont use

    Low accuracy of bloodoxygenation

    tissue perfusion pressure

    cant measure

    http://en.wikipedia.org/wiki/Invasiveness_of_surgical_procedureshttp://en.wikipedia.org/wiki/Fingertiphttp://en.wikipedia.org/wiki/Fingertiphttp://en.wikipedia.org/wiki/Fingertiphttp://en.wikipedia.org/wiki/Earlobehttp://en.wikipedia.org/wiki/Earlobehttp://en.wikipedia.org/wiki/Earlobehttp://en.wikipedia.org/wiki/Infanthttp://en.wikipedia.org/wiki/Infanthttp://en.wikipedia.org/wiki/Earlobehttp://en.wikipedia.org/wiki/Fingertiphttp://en.wikipedia.org/wiki/Invasiveness_of_surgical_procedures
  • 8/9/2019 ATI Khaled khalilia

    22/39

    Khaled khalilia

    22

    Pulse oxymetry:

    More info:http://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdf

    Video 1:http://www.youtube.com/watch?v=9PSXruEjBlY

    Video 2:http://www.youtube.com/watch?v=NJwiDz4NquI

    Video 3:http://www.youtube.com/watch?v=Tsj7q-CkojI

    http://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdfhttp://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdfhttp://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdfhttp://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdfhttp://www.youtube.com/watch?v=9PSXruEjBlYhttp://www.youtube.com/watch?v=9PSXruEjBlYhttp://www.youtube.com/watch?v=9PSXruEjBlYhttp://www.youtube.com/watch?v=NJwiDz4NquIhttp://www.youtube.com/watch?v=NJwiDz4NquIhttp://www.youtube.com/watch?v=NJwiDz4NquIhttp://www.youtube.com/watch?v=Tsj7q-CkojIhttp://www.youtube.com/watch?v=Tsj7q-CkojIhttp://www.youtube.com/watch?v=Tsj7q-CkojIhttp://www.youtube.com/watch?v=Tsj7q-CkojIhttp://www.youtube.com/watch?v=NJwiDz4NquIhttp://www.youtube.com/watch?v=9PSXruEjBlYhttp://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdfhttp://windward.hawaii.edu/facstaff/miliefsky-m/ZOOL%20142L/aboutPulseOximetry.pdf
  • 8/9/2019 ATI Khaled khalilia

    23/39

    Khaled khalilia

    23

    6.Monitoring of arterial blood pressure.

    Non-invasive:

    Palpation: A minimum systolic value can be roughly estimatedbypalpation, most often used inemergency situations, but should be usedwith caution. The diastolic blood pressure cannot be estimated by this method

    Auscultation: uses astethoscope and asphygmomanometer. Thiscomprises an inflatable (Riva-Rocci)cuffplaced around the upperarm at

    roughly the same vertical height as the heart, attached to a mercuryoraneroidmanometer

    Oscilometric:requires less skill than the auscultatory technique and may besuitable for use by untrained staff and for automated patient home monitoring.

    CNAP:Continuous Noninvasive Arterial Pressure.

    PWV:pulse wave velocityprincipleInvasive:

    This technique involves direct measurement of arterial pressure byinserting a cannula needle in a suitable artery. The cannula must be

    connected to a sterile, fluid-filled system, which is connected to an

    electronic patient monitor. (usuallyradial,femoral,dorsalis

    pedis orbrachial). Used inintensive care medicine,anesthesiology.

    Advantages:

    Blood sample

    Repeatable

    Real time measurement

    Accuracy (high)

    Obtain other

    Disadvantages:

    Complication:ischemia,thrombosis,bleeding,infection.

    Require experience

    Require special equipment

    More info: https://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-blood

    Video 1:http://www.youtube.com/watch?v=WHXP339YjF0

    Video 2:http://www.youtube.com/watch?v=5TahRMklod8

    Video 3:http://www.youtube.com/watch?v=YM3iXS146Yc

    http://en.wikipedia.org/wiki/Palpationhttp://en.wikipedia.org/wiki/Emergency_medical_servicehttp://en.wikipedia.org/wiki/Stethoscopehttp://en.wikipedia.org/wiki/Sphygmomanometerhttp://en.wikipedia.org/wiki/Scipione_Riva-Roccihttp://en.wikipedia.org/wiki/Scipione_Riva-Roccihttp://en.wikipedia.org/wiki/Scipione_Riva-Roccihttp://en.wikipedia.org/wiki/Cuffhttp://en.wikipedia.org/wiki/Armhttp://en.wikipedia.org/wiki/Aneroidhttp://en.wikipedia.org/wiki/Aneroidhttp://en.wikipedia.org/wiki/Continuous_Noninvasive_Arterial_Pressurehttp://en.wikipedia.org/wiki/Continuous_Noninvasive_Arterial_Pressurehttp://en.wikipedia.org/wiki/Pulse_wave_velocityhttp://en.wikipedia.org/wiki/Radial_arteryhttp://en.wikipedia.org/wiki/Femoral_arteryhttp://en.wikipedia.org/wiki/Dorsalis_pedis_arteryhttp://en.wikipedia.org/wiki/Dorsalis_pedis_arteryhttp://en.wikipedia.org/wiki/Brachial_arteryhttp://en.wikipedia.org/wiki/Intensive_care_medicinehttp://en.wikipedia.org/wiki/Anesthesiologyhttps://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-bloodhttps://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-bloodhttps://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-bloodhttp://www.youtube.com/watch?v=WHXP339YjF0http://www.youtube.com/watch?v=WHXP339YjF0http://www.youtube.com/watch?v=WHXP339YjF0http://www.youtube.com/watch?v=5TahRMklod8http://www.youtube.com/watch?v=5TahRMklod8http://www.youtube.com/watch?v=5TahRMklod8http://www.youtube.com/watch?v=YM3iXS146Ychttp://www.youtube.com/watch?v=YM3iXS146Ychttp://www.youtube.com/watch?v=YM3iXS146Ychttp://www.youtube.com/watch?v=YM3iXS146Ychttp://www.youtube.com/watch?v=5TahRMklod8http://www.youtube.com/watch?v=WHXP339YjF0https://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-bloodhttps://www.inkling.com/read/manual-clinical-anesthesiology-chu-fuller-1st/chapter-11/invasive-arterial-bloodhttp://en.wikipedia.org/wiki/Anesthesiologyhttp://en.wikipedia.org/wiki/Intensive_care_medicinehttp://en.wikipedia.org/wiki/Brachial_arteryhttp://en.wikipedia.org/wiki/Dorsalis_pedis_arteryhttp://en.wikipedia.org/wiki/Dorsalis_pedis_arteryhttp://en.wikipedia.org/wiki/Femoral_arteryhttp://en.wikipedia.org/wiki/Radial_arteryhttp://en.wikipedia.org/wiki/Pulse_wave_velocityhttp://en.wikipedia.org/wiki/Continuous_Noninvasive_Arterial_Pressurehttp://en.wikipedia.org/wiki/Aneroidhttp://en.wikipedia.org/wiki/Aneroidhttp://en.wikipedia.org/wiki/Armhttp://en.wikipedia.org/wiki/Cuffhttp://en.wikipedia.org/wiki/Scipione_Riva-Roccihttp://en.wikipedia.org/wiki/Sphygmomanometerhttp://en.wikipedia.org/wiki/Stethoscopehttp://en.wikipedia.org/wiki/Emergency_medical_servicehttp://en.wikipedia.org/wiki/Palpation
  • 8/9/2019 ATI Khaled khalilia

    24/39

    Khaled khalilia

    24

  • 8/9/2019 ATI Khaled khalilia

    25/39

    Khaled khalilia

    25

    7.monitoring of body temperature:

    Fever:

    Infection(pneumonia)

    Medication,AB Trauma

    Injurey

    Heat attack

    Burns

    Arthritis

    Cancer

    Hyperthyroidism

    Silicosis

    SunburnHypothermia:

    Cold exposure

    Shock

    Alcohol

    Drugs

    Diabetes

    Hypothyroidism

    SepsisSites of measurements:

    Oral cavity (accurate)

    Armpit (inaccurate)

    Rectal (most accurate)

    Axilla

    Esophagus

    Urinary bladder

    Temporal artery

    Vagina Ear

    Measurements devices:

    Mercury thermometer

    Digital

    infrared

    37.0 C (98.6 F)- Normal internal body temperature (which variesbetween about 36.1237.5 C (97.0299.5 F))

    35 C (95 F)- (Hypothermiais less than 35 C (95 F)) - Intense shivering,

    numbness and bluish/grayness of the skin.

    32 C (90 F)- (Medical emergency) Hallucinations, delirium, complete

    confusion, extreme sleepiness that is progressively becoming comatose.

    39 C (102 F)- (Pyrexia) - Severe sweating, flushed and very red. Fast

    heart rate and breathlessness.

    41 C (106 F)- (Medical emergency) - Fainting, vomiting, severe

    headache, dizziness, confusion, hallucinations, delirium and drowsiness can

    occur.

    More info about body temperature regulation:

    Video 1:http://www.youtube.com/watch?v=ZywM3DN-eo0

    Video 2:http://www.youtube.com/watch?v=DrdRIwD2v5g

    http://en.wikipedia.org/wiki/Hypothermiahttp://en.wikipedia.org/wiki/Hypothermiahttp://en.wikipedia.org/wiki/Hypothermiahttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Pyrexiahttp://en.wikipedia.org/wiki/Pyrexiahttp://en.wikipedia.org/wiki/Pyrexiahttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Medical_emergencyhttp://www.youtube.com/watch?v=ZywM3DN-eo0http://www.youtube.com/watch?v=ZywM3DN-eo0http://www.youtube.com/watch?v=ZywM3DN-eo0http://www.youtube.com/watch?v=DrdRIwD2v5ghttp://www.youtube.com/watch?v=DrdRIwD2v5ghttp://www.youtube.com/watch?v=DrdRIwD2v5ghttp://www.youtube.com/watch?v=DrdRIwD2v5ghttp://www.youtube.com/watch?v=ZywM3DN-eo0http://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Pyrexiahttp://en.wikipedia.org/wiki/Medical_emergencyhttp://en.wikipedia.org/wiki/Hypothermia
  • 8/9/2019 ATI Khaled khalilia

    26/39

    Khaled khalilia

    26

    8.Normal salineindications, advantages, adverse effects.

    Indication:

    Iv.infusion (in hypovolemia,no

    fluid intake) Contact lense solution

    Nasal irrigation

    Clean piercing

    Flushwounds + skin abrasions

    Combined with dextroseglucose

    Source of water and electrolytesAdverse effect:

    Infection Thrombosis

    Phlebitis

    Hypervolemia Metabolic acidosis

    Interstitial edemaAdvantages:

    Easy and available

    Reduce risk

    CheapContraindication:

    Hypertension

    Pulmonary edema

    Dose: 1.5-3 liter/day

    0.9% Sodium Chloride Solution = 9 g/L

    Isotonic crystalloid solution

    The pH is 5.0 (4.5 to 7.0).

    osmolarity = 308 mOsmol/L.

    contains 154 mEq/L Sodium and Chloride.

    If used to replenish fluids, a large bore IV (18G or more) should be started,hung with a 1000 mL bag of saline.

    should be used with great care, if at all, in patients with congestive heartfailure, severe renal insufficiency and in clinical states in which there exists

    edema with sodium retention.

    check BP and lung sounds every 250cc. Discontinue bolus if pulmonaryedema is discovered, or once BP is in therapeutic range (generally SBP above90 mm/Hg). Avoid hypervolemia.

  • 8/9/2019 ATI Khaled khalilia

    27/39

    Khaled khalilia

    27

    9. Ringer lactate solution indications, advantages, adverse

    effects:Indication:

    in blood loss

    trauma surgery

    burn

    to prevent acidosis

    supply water andelectrolytes (e.g.,calcium, potassium, sodium,

    chloride)

    contraindication:

    severe metabolic acidosis

    alkalosis

    and in severe liver disease anoxic states which affect

    lactate metabolism.Adverse effect:

    Edema

    Infection

    Thrombosis

    Phlebitis

    Hypervolemia

    Arrhythmia

    pH: 6.2 (6.07.5)

    Osmolarity: 275 mOsmol/liter

    intravenous administration orsubcutaneously.

    Dose: 20-30 ml/kg/hr

    Na = 130mmol/L,Cl = 109 ,lactate = 28, K = 4, Ca = 1.5 crystalloids:includesaline anddextrose solutions

    This solution should be used with care in patients with hypervolemia, renalinsufficiency, urinary tract obstruction, or impending or frank cardiac

    decompensation.

    http://www.medicinenet.com/electrolytes/article.htmhttp://en.wikipedia.org/wiki/Intravenous_therapyhttp://en.wikipedia.org/wiki/Subcutaneoushttp://en.wikipedia.org/wiki/Molarity#Molarityhttp://en.wikipedia.org/wiki/Volume_expander#Crystalloidshttp://en.wikipedia.org/wiki/Saline_(medicine)http://en.wikipedia.org/wiki/Intravenous_sugar_solutionhttp://en.wikipedia.org/wiki/Intravenous_sugar_solutionhttp://en.wikipedia.org/wiki/Saline_(medicine)http://en.wikipedia.org/wiki/Volume_expander#Crystalloidshttp://en.wikipedia.org/wiki/Molarity#Molarityhttp://en.wikipedia.org/wiki/Subcutaneoushttp://en.wikipedia.org/wiki/Intravenous_therapyhttp://www.medicinenet.com/electrolytes/article.htm
  • 8/9/2019 ATI Khaled khalilia

    28/39

    Khaled khalilia

    28

    10.Water balance: the ratio between the water assimilated into the body and that lost from the body

    more info and video:

    video 1:http://www.youtube.com/watch?v=mp_3CIUqFU8video 2:http://www.youtube.com/watch?v=QDkLc1GV7Cg

    video 3:http://www.youtube.com/watch?v=11a1fXbTf7g

    http://www.youtube.com/watch?v=mp_3CIUqFU8http://www.youtube.com/watch?v=mp_3CIUqFU8http://www.youtube.com/watch?v=QDkLc1GV7Cghttp://www.youtube.com/watch?v=QDkLc1GV7Cghttp://www.youtube.com/watch?v=QDkLc1GV7Cghttp://www.youtube.com/watch?v=11a1fXbTf7ghttp://www.youtube.com/watch?v=11a1fXbTf7ghttp://www.youtube.com/watch?v=11a1fXbTf7ghttp://www.youtube.com/watch?v=11a1fXbTf7ghttp://www.youtube.com/watch?v=QDkLc1GV7Cghttp://www.youtube.com/watch?v=mp_3CIUqFU8
  • 8/9/2019 ATI Khaled khalilia

    29/39

    Khaled khalilia

    29

  • 8/9/2019 ATI Khaled khalilia

    30/39

    Khaled khalilia

    30

  • 8/9/2019 ATI Khaled khalilia

    31/39

    Khaled khalilia

    31

    11.Macromolecular solutionsindications, advantages,adverse effects, examples.

    Colloid solution

    Dextrans: dextran 70, dextran 40Gelatins: Gelofusin, Haemacel, Eufusin

    Human albumin 5%, 20%

    dimensions between 2 to 1000 nanometers.

    Indication:

    Hypovolemia

    Shock

    Spinal anesthesia(prevent hypotension)

    Plasma exchange Preoperative/postoperative

    Hypoalbuminemia

    Prophylaxis (v.thrombosis op)Advantages:

    Good volume replacement

    Large duration of intravasculat remanence (wtf!!)Disadvantages:

    Expensive

    Risk of anaphylactic reaction Determine coagulation disorders

    Nausea, vomiting

    Headache

    Interfere with blood groupsdetermination!!

    TachycardiaContraindication:

    Renal failureCongestive heart failure

    (maybe!!)

  • 8/9/2019 ATI Khaled khalilia

    32/39

    Khaled khalilia

    32

    12.Dopaminemechanism of action, indications, adverse effects.

    Mechanism of action:

    5-10 g/kg/min sympathikus:

    Heart muscle contraction

    heart rate

    cardiac output

    blood pressure

    10-20 g/kg/min Vasoconstriction BP

    Vasopressor + Inotropic

    Indication:

    Hypotension

    Bradycardia

    Cardiac arrest

    Shock (cardiogenic shock)

    Heart failureAdverse effect:

    Chest pain

    Difficult urination

    Weakness

    Nausea , vomiting

    Headache

    Difficult breathing

    Angina

    Irregular heartbeat

    azotemia

  • 8/9/2019 ATI Khaled khalilia

    33/39

    Khaled khalilia

    33

    13.Dobutaminemechanism of action, indications, adverse effects.

    Dose:Continuous infusion: 2.5-15 mcg/kg/min IV

    0.5-1 initially, then 2-20 not to exceed 40 mcg/kg/min

    Mechanism of action:

    Stimulation of 1-receptors (sympathikus):

    + inotropic

    contractility

    cardiac output

    Indication: Heart failure ( R + L ) increase the stroke volume

    Cardiogenic shock

    Septic shock

    Congestive heart failure ( cardiac output )

    During heart surgery

    Adverse effect:

    Hypertension Arrhythmia

    Angina

    Tachycardia

    Palpitation

    O2-consumption

    http://opencalc%28%27/calculator/dosing/iv-drip-dosing','Low%20Cardiac%20Output','Adult','Continuous%20infusion:%202.5-15%20mcg/kg/min%20IV');http://opencalc%28%27/calculator/dosing/iv-drip-dosing','Low%20Cardiac%20Output','Adult','Continuous%20infusion:%202.5-15%20mcg/kg/min%20IV');
  • 8/9/2019 ATI Khaled khalilia

    34/39

    Khaled khalilia

    34

    14. Adrenalinemechanism of action, indications, adverse effects.

    Mechanism of action:stimulate 1,1,2 adrenergic receptor:

    Relaxation of bronchial smooth muscleCardiac stimulation, HR

    Dilation in skeletal muscle

    Lung: respiratory rate

    Liver: glycogenolysis

    Muscle: glycolysis

    Dose:1mg every 3-5 min (I.V or intratracheal)

    Indication:

    Cardiac arrest Anaphylaxis

    Bronchospasm

    Hypoglycemia

    Asthma

    Hypotension

    Bradycardia

    Anaphylactic shock

    Glaucoma

    Hemostatic In local anesthesia

    Adverse effect:

    Tachycardia

    Palpitation

    Arrhythmia

    Anxiety

    Panic attack

    Hypertension

    Pulmonary edema Angina pain

    Contraindication:

    Hyperthyroidism

    Ischemic heart disease

    Angle-closure glaucoma

    Hypertension

  • 8/9/2019 ATI Khaled khalilia

    35/39

    Khaled khalilia

    35

    15. Noradrenalinemechanism of action, indications, adverse effects.

    Mechanism of action:

    : constrictor of blood vessel, BP, Bloodflow high Dose

    : Heart (dilate coronary artery) ,inotropic +Small Doseindication:

    with local anesthesia

    septic shock (for refractory hypotension)

    anaphylactic shock

    hemostaticadverse effect:

    bradycardia

    headache

    hypertension

    diarrhea

    dizziness

    bleeding

    dry skindose:

    (initial): 8 to 12 mcg/min -titrate to BP. Usual maintenance: 2 to 4 mcg/min.

    doses as high as 0.5 to 1.5 mcg/kg/min for 1-10days have been used inseptic shock.

    Calculation of drip rate 8 mg/ 250 ml (ml/hr) = mcg/min x 1.875.Administer through a central line (large vein).

    more info:http://www.medsafe.govt.nz/profs/datasheet/n/noradrenalineinf.pdf

    http://www.medsafe.govt.nz/profs/datasheet/n/noradrenalineinf.pdfhttp://www.medsafe.govt.nz/profs/datasheet/n/noradrenalineinf.pdfhttp://www.medsafe.govt.nz/profs/datasheet/n/noradrenalineinf.pdfhttp://www.medsafe.govt.nz/profs/datasheet/n/noradrenalineinf.pdf
  • 8/9/2019 ATI Khaled khalilia

    36/39

    Khaled khalilia

    36

    Clinical case: Respiratory failure

    ARDS

    Acute renal failure

    Chronic renal failure

    Hypovolemic shock

    Cardiogenic shock

    Septic shock

    Anaphylactic shock

    Tachycardia, Bradycardia

    Acid-base-disturbances

    Acidosis: respiratory + metabolic Alcalosis: respiratory + metabolic

    Electrolyte disturbances

    Hypernatremia

    Hyponatremia

    Hyperkalemia

    Hypokalemia

  • 8/9/2019 ATI Khaled khalilia

    37/39

    Khaled khalilia

    37

    Laboratory Test Normal Range in USUnits

    Normal Range in SIUnits

    ToConvertUS to SIUnits

    ALT (Alanineaminotransferase)

    W 7-30 units/literM 10-55 units/liter

    W 0.12-0.50 kat/literM 0.17-0.92 kat/liter

    x 0.01667

    Albumin 3.1 - 4.3 g/dl 31 - 43 g/liter x 10

    AlkalinePhosphatase W 30-100 units/literM 45-115 units/liter W 0.5-1.67 kat/literW 0.75-1.92 kat/liter x 0.01667

    Amylase (serum) 53-123 units/liter 0.88-2.05 nkat/liter x 0.01667

    AST (Aspartateaminotransferase)

    W 9-25 units/literM 10-40 units/liter

    W 0.15-0.42 kat/literM 0.17-0.67 kat/liter

    x 0.01667

    Basophils 0-3% of lymphocytes 0.0-0.3 fraction of whiteblood cells

    x 0.01

    Bilirubin - Direct 0.0-0.4 mg/dl 0-7 mol/liter x 17.1

    Bilirubin - Total 0.0-1.0 mg/dl 0-17 mol/liter x 17.1

    Blood pressure Normal: 120/70 to 120/80 millimeters of mercury(mmHg). The top number is systolic pressure,

    when the heart is pumping. Bottom number isdiastolic pressure then the heart is at rest. Bloodpressure can be too low (hypotension) or too high(hypertension).

    Noconversion

    C peptide 0.5-2.0 ng/ml 0.17-0.66 nmol/liter x 0.33

    Calcium, serum 8.5 -10.5 mg/dl 2.1-2.6 mmol/liter x 0.25

    Calcium, urine 0-300 mg/24h 0.0-7.5 mmol/24h x 0.025

    Cholesterol, totalDesirableMarginalHigh

    239 mg/dL6.18 mmol/liter

    x 0.02586

    Cholesterol, LDLDesirableMarginal

    HighVery High

    190 mg/dL 4.91 mmol/literx 0.02586

    Cholesterol, HDLDesirable >60 mg/dL >1.55 mmol/liter

    x 0.02586

  • 8/9/2019 ATI Khaled khalilia

    38/39

    Khaled khalilia

    38

    ModerateLow (heart risk)

    40-60 mg/dL 1.03-1.55 mmol/liter

    Cortisol: serum 0-25 g/dl (depends ontime of day)

    0-690 nmol/liter x 27.59

    Cortisol: free

    (urine)

    20-70 g/dl 55-193 nmol/24h x 2.759

    Creatine kinase W 40-150 units/liter

    M 60-400 units/liter

    W 0.67-2.50 kat/liter

    M 1.00-6.67 kat/liter

    x 0.01667

    DHEA W 130-980 ng/dlM 180-1250 ng/dl

    W 4.5-34.0 nmol/literM 6.24-43.3 nmol/liter

    x 0.03467

    DHEASulfate W Pre-menopause: 12-535 g/dlW Post-menopause: 30-260 g/dlM 10-619 g/dl

    W Pre-menopause: 120-5350 g/literW Post-menopause: 300-2600 g/literM 100-6190 g/liter

    x 10

    Eosinophils 0-8% of white blood cells 0.0-0.8 fraction of white

    blood cells

    x 0.01

    Erythrocytesedimentationrate (Sed Rate)

    W M W M Noconversion

    Folate 3.1-17.5 ng/ml 7.0-39.7 nmol/liter x 2.266

    Glucose, urine x 0.05551

    Glucose, plasma 70-110 mg/dl 3.9-6.1 mmol/liter x 0.05551

    GGT (Gammaglutamyltransferase)

    W M W M Noconversion

    Hematocrit W 36.0% - 46.0% of red

    blood cellsM 37.0% - 49.0% of redblood cells

    W 0.36-0.46 fraction of

    red blood cellsM 0.37-0.49 fraction ofred blood cells

    x 0.01

    Hemoglobin W 12.0-16.0 g/dlM 13.0-18.0 g/dl

    W 7.4-9.9 mmol/literM 8.1-11.2 mmol/liter

    x 0.6206

    LDH (Lactatedehydrogenase)(total)

    x0.016667

    Lactic acid 0.5-2.2 mmol/liter 0.5-2.2 mmol/liter Noconversion

    Leukocytes (WBC) 4.5-11.0x103/mm3 4.5-11.0x109/liter No

    conversionLymphocytes 16%-46% of white blood

    cells0.16-0.46 fraction ofwhite blood cells

    x 0.01

    Mean corpuscularhemoglobin(MCH)

    25.0-35.0 pg/cell 25.0-35.0 pg/cell Noconversion

    Mean corpuscularhemoglobin

    31.0-37.0 g/dl 310-370 g/liter x 10

    http://www.thebody.com/content/art6029.html?ic=4001http://www.thebody.com/content/art6029.html?ic=4001http://www.thebody.com/content/art6029.html?ic=4001
  • 8/9/2019 ATI Khaled khalilia

    39/39

    concentration(MCHC)

    MCV (Meancorpuscularvolume)

    W 78-102 m3M 78-100 m3

    W 78-102 flM 78-100 fl

    Noconversion

    Monocytes 4-11% of white bloodcells 0.04-0.11 fraction ofwhite blood cells x 0.01

    Neutrophils 45%-75% of white bloodcells

    0.45-0.75 fraction ofwhite blood cells

    x 0.01

    Phosphorus 2.5 4.5 mg/dL 0.81-1.45 mmol/L x 0.323

    Platelets(Thrombocytes)

    130 400 x 10 3L 130 400 x 10 9L Noconversion

    Potassium 3.4-5.0 mmol/liter 3.4-5.0 mmol/liter Noconversion

    RBC (Red bloodcell count)

    W 3.9 5.2 x 106/L3M 4.4 5.8 x 10 6/L3

    W 3.9 5.2 x 1012/LM 4.4 5.8 x 10 12/L

    Noconversion

    Sodium 135-145 mmol/liter 135-145 mmol/liter Noconversion

    Testosterone,total (morningsample)

    W 6-86 ng/dlM 270-1070 ng/dl

    W 0.21-2.98 nmol/literM 9.36-37.10 nmol/liter

    x 0.03467

    Testosterone, freeAge 20-40

    Age 41-60

    Age 61-80

    W 0.6-3.1,M 15.0-40.0 pg/mlW 0.4-2.5,M 13.0-35.0 pg/ml

    W 0.2-2.0,M 12.0-28.0 pg/ml

    W 20.8-107.5,M 520-1387 pmol/literW 13.9-86.7,M 451-1213 pmol/liter

    W 6.9-69.3,M 416-971 pmol/liter

    x 34.67

    Triglicerides(fasting)NormalBorderlineHighVery high

    40-150 mg/dl150-200 mg/dl200-500 mg/dl>500 mg/dl

    0.45-1.69 mmol/liter1.69-2.26 mmol/liter2.26-5.65 mmol/liter>5.65 mmol/liter

    x 0.01129

    Urea, plasma(BUN)

    8-25 mg/dl 2.9-8.9 mmol/liter x 0.357

    Urinalysis - pHSpecific gravity 5.0-9.01.001-1.035 5.0-9.01.001-1.035 Noconversion

    WBC (White bloodcells, leukocytes)

    4.5-11.0x10 3/mm 3 4.5-11.0x10 9liter Noconversion