automated segmentation and motion correction of the fetal brain

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Automated segmentation and motion correction of the fetal brain Kevin Keraudren Imperial College London December 6 th , 2013

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These slides are associated with the following NeuroImage publication: Keraudren, K., Kuklisova-Murgasova, M., Kyriakopoulou, V., Malamateniou, C., Rutherford, M.A., Kainz, B., Hajnal, J.V., Rueckert, D., Automated Fetal Brain Segmentation from 2D MRI Slices for Motion Correction, NeuroImage (2014), doi: 10.1016/j.neuroimage.2014.07.023 http://www.sciencedirect.com/science/article/pii/S1053811914005953 For more details on using an XKCD style for latex beamer, visit: http://kevin-keraudren.blogspot.co.uk/2014/03/xkcd-style-beamer-presentation-latex.html

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Automated segmentation and motioncorrection of the fetal brain

Kevin KeraudrenImperial College London

December 6th, 2013

Problem

As the fetuse moves

the data is acquired as stacks of misaligned 2D slices

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Problemorthogonal

stacks of 2D slices3D volume

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Definitions

recall=Volume of correctly classified voxels

Ground truth volume of the brain

recall=TP

TP + FN

precision=Volume of correctly classified voxels

Detected volume of the brain

precision=TP

TP + FP

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Idea

99%

91%

96%

93%

Box detection

RF/CRF segmentation

Enlarged segmentation

Final segmentation

0

20

40

60

80

100

recallprecision

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Box detection

MSERSize

filteringBag-of-SIFT RANSAC

MSER regions Filtering by size andBag-of-Words

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Box detection

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Brain extractionRandom Forest classifier

and Conditional Random Field

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Motion correction

Acquisition ofsnapshot images

Automatedmasking

Volumeregistration

Slice to volumeregistration

Update slicessegmentation

Robust statisticsand superresolution

Reconstructedvolume

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Motion correction

Conditional Random Field

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Result

Tighter mask, less artifactsand brain already extracted

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Acknowledgements

Collaborators:Maria Murgasova, Vanessa Kyriakopoulou,Christina Malamateniou, Mary Rutherford,Bernhard Kainz, Jo Hajnal & Daniel Rueckert

XKCD for Matplotlib, Latex and Tikz:Jake Vanderplas, Damon McDougall, JohannesBuchner, percusse

www.doc.ic.ac.uk/~kpk09/

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