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Author Index Volumes 101–108 Author Index Volumes 1–50 see Volume 50 Author Index Volumes 51–100 see Volume 100 Acker, J. P.: Biopreservation of Cells and Engineered Tissues. Vol. 103, pp. 157–187. Aerni, P.: Agricultural Biotechnology and its Contribution to the Global Knowledge Econ- omy. Vol. 107, pp. 69–96. Ahn, E. S. see Webster, T.J.: Vol. 103, pp. 275–308. Ahring, B. K. and Westermann, P.: Coproduction of Bioethanol with Other Biofuels. Vol. 108, pp. 289–302. Alapuranen, M., see Viikari, L.: Vol. 108, pp. 121–145. Andreadis S. T.: Gene-Modified Tissue-Engineered Skin: The Next Generation of Skin Substitutes. Vol. 103, pp. 241–274. Arrigo, N. see Felber, F.: Vol. 107, pp. 173–205. Babiak, P., see Reymond, J.-L.: Vol. 105, pp. 31–58. Backendorf, C. see Fischer, D. F.: Vol. 104, pp. 37–64 Bauser, H. see Schrell, A.: Vol. 107, pp. 13–39. Becker, T., Hitzmann, B., Muffler, K., Pörtner, R., Reardon, K. F., Stahl, F. and Ulber, R.: Future Aspects of Bioprocess Monitoring. Vol. 105, pp. 249–293. Beier, V., Mund, C., and Hoheisel, J. D.: Monitoring Methylation Changes in Cancer. Vol. 104, pp. 1–11. van Beilen, J. B., Poirier, Y.: Prospects for Biopolymer Production in Plants. Vol. 107, pp. 133– 151. Berlin, A., see Chandra, R.P.: Vol. 108, pp. 67–93. Berthiaume, F. see Nahmias, Y.: Vol. 103, pp. 309–329. Bhatia, S. N. see Tsang, V.L.: Vol. 103, pp. 189–205. Biener, R. see Goudar, C.: Vol. 101, pp. 99–118. Bigler, F. see Sanvido, O.: Vol. 107, pp. 235–278. Borchert, T. V., see Schäfer, T.: Vol. 105, pp. 59–131. Brunner, H. see Schrell, A.: Vol. 107, pp. 13–39. Bulyk, M. L.: Protein Binding Microarrays for the Characterization of DNA–Protein Inter- actions. Vol. 104, pp. 65–85. Bura, R., see Chandra, R.P.: Vol. 108, pp. 67–93. Chan, C. see Patil, S.: Vol. 102, pp. 139–159. Chandra, R. P., Bura, R., Mabee, W.E., Berlin, A., Pan, X. and Saddler, J. N.: Substrate Pre- treatment: The Key to Effective Enzymatic Hydrolysis of Lignocellulosics?. Vol. 108, pp. 67–93. Cherry, J., see Merino, S.T.: Vol. 108, pp. 95–120. Chuppa, S. see Konstantinov, K.: Vol. 101, pp. 75–98. van Dijken, J. P., see van Maris, A. J. A.: Vol. 108, pp. 179–204.

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Author Index Volumes 101–108

Author Index Volumes 1–50 see Volume 50Author Index Volumes 51–100 see Volume 100

Acker, J. P.: Biopreservation of Cells and Engineered Tissues. Vol. 103, pp. 157–187.Aerni, P.: Agricultural Biotechnology and its Contribution to the Global Knowledge Econ-

omy. Vol. 107, pp. 69–96.Ahn, E. S. see Webster, T. J.: Vol. 103, pp. 275–308.Ahring, B. K. and Westermann, P.: Coproduction of Bioethanol with Other Biofuels. Vol. 108,

pp. 289–302.Alapuranen, M., see Viikari, L.: Vol. 108, pp. 121–145.Andreadis S. T.: Gene-Modified Tissue-Engineered Skin: The Next Generation of Skin

Substitutes. Vol. 103, pp. 241–274.Arrigo, N. see Felber, F.: Vol. 107, pp. 173–205.

Babiak, P., see Reymond, J.-L.: Vol. 105, pp. 31–58.Backendorf, C. see Fischer, D. F.: Vol. 104, pp. 37–64Bauser, H. see Schrell, A.: Vol. 107, pp. 13–39.Becker, T., Hitzmann, B., Muffler, K., Pörtner, R., Reardon, K. F., Stahl, F. and Ulber, R.: Future

Aspects of Bioprocess Monitoring. Vol. 105, pp. 249–293.Beier, V., Mund, C., and Hoheisel, J. D.: Monitoring Methylation Changes in Cancer. Vol. 104,

pp. 1–11.van Beilen, J. B., Poirier, Y.: Prospects for Biopolymer Production in Plants. Vol. 107, pp. 133–

151.Berlin, A., see Chandra, R. P.: Vol. 108, pp. 67–93.Berthiaume, F. see Nahmias, Y.: Vol. 103, pp. 309–329.Bhatia, S. N. see Tsang, V. L.: Vol. 103, pp. 189–205.Biener, R. see Goudar, C.: Vol. 101, pp. 99–118.Bigler, F. see Sanvido, O.: Vol. 107, pp. 235–278.Borchert, T. V., see Schäfer, T.: Vol. 105, pp. 59–131.Brunner, H. see Schrell, A.: Vol. 107, pp. 13–39.Bulyk, M. L.: Protein Binding Microarrays for the Characterization of DNA–Protein Inter-

actions. Vol. 104, pp. 65–85.Bura, R., see Chandra, R. P.: Vol. 108, pp. 67–93.

Chan, C. see Patil, S.: Vol. 102, pp. 139–159.Chandra, R. P., Bura, R., Mabee, W. E., Berlin, A., Pan, X. and Saddler, J. N.: Substrate Pre-

treatment: The Key to Effective Enzymatic Hydrolysis of Lignocellulosics?. Vol. 108,pp. 67–93.

Cherry, J., see Merino, S. T.: Vol. 108, pp. 95–120.Chuppa, S. see Konstantinov, K.: Vol. 101, pp. 75–98.

van Dijken, J. P., see van Maris, A. J. A.: Vol. 108, pp. 179–204.

360 Author Index Volumes 101–108

Dybdal Nilsson, L., see Schäfer, T.: Vol. 105, pp. 59–131.

Einsele, A.: The Gap between Science and Perception: The Case of Plant Biotechnology inEurope. Vol. 107, pp. 1–11.

Farid, S. S.: Established Bioprocesses for Producing Antibodies as a Basis for Future Plan-ning. Vol. 101, pp. 1–42.

Felber, F., Kozlowski, G., Arrigo, N., Guadagnuolo, R.: Genetic and Ecological Consequencesof Transgene Flow to the Wild Flora. Vol. 107, pp. 173–205.

Field, S., Udalova, I., and Ragoussis, J.: Accuracy and Reproducibility of Protein–DNA Mi-croarray Technology. Vol. 104, pp. 87–110.

Fischer, D. F. and Backendorf, C.: Identification of Regulatory Elements by Gene FamilyFootprinting and In Vivo Analysis. Vol. 104, pp. 37–64.

Fisher, R. J. and Peattie, R. A.: Controlling Tissue Microenvironments: Biomimetics, Trans-port Phenomena, and Reacting Systems. Vol. 103, pp. 1–73.

Fisher, R. J. see Peattie, R. A.: Vol. 103, pp. 75–156.Franco-Lara, E., see Weuster-Botz, D.: Vol. 105, pp. 205–247.

Galbe, M. and Zacchi, G.: Pretreatment of Lignocellulosic Materials for Efficient BioethanolProduction. Vol. 108, pp. 41–65.

Galbe, M., Sassner, P., Wingren, A. and Zacchi, G.: Process Engineering Economics ofBioethanol Production. Vol. 108, pp. 303–327.

Garlick, J. A.: Engineering Skin to Study Human Disease – Tissue Models for Cancer Biologyand Wound Repair. Vol. 103, pp. 207–239.

Gessler, C., Patocchi, A.: Recombinant DNA Technology in Apple. Vol. 107, pp. 113–132.Gibson, K., see Schäfer, T.: Vol. 105, pp. 59–131.Gorwa-Grauslund, M. F., see Hahn-Hägerdal, B.: Vol. 108, pp. 147–177.Goudar, C. see Konstantinov, K.: Vol. 101, pp. 75–98.Goudar, C., Biener, R., Zhang, C., Michaels, J., Piret, J. and Konstantinov, K.: Towards In-

dustrial Application of Quasi Real-Time Metabolic Flux Analysis for Mammalian CellCulture. Vol. 101, pp. 99–118.

Grabar, T. B., see Jarboe, L. R.: Vol. 108, pp. 237–261.Guadagnuolo, R. see Felber, F.: Vol. 107, pp. 173–205.

den Haan, R., see van Zyl, W. H.: Vol. 108, pp. 205–235.Hahn-Hägerdal, B., Karhumaa, K., Jeppsson, M. and Gorwa-Grauslund, M. F.: Metabolic

Engineering for Pentose Utilization in Saccharomyces cerevisiae. Vol. 108, pp. 147–177.Hatzack, F., see Schäfer, T.: Vol. 105, pp. 59–131.Hekmat, D., see Weuster-Botz, D.: Vol. 105, pp. 205–247.Heldt-Hansen, H. P., see Schäfer, T.: Vol. 105, pp. 59–131.Hilterhaus, L. and Liese, A.: Building Blocks. Vol. 105, pp. 133–173.Hitzmann, B., see Becker, T.: Vol. 105, pp. 249–293.Hoheisel, J. D. see Beier, V.: Vol. 104, pp. 1–11Holland, T. A. and Mikos, A. G.: Review: Biodegradable Polymeric Scaffolds. Improvements

in Bone Tissue Engineering through Controlled Drug Delivery. Vol. 102, pp. 161–185.Hossler, P. see Seth, G.: Vol. 101, pp. 119–164.Høst Pedersen, H., see Schäfer, T.: Vol. 105, pp. 59–131.Hu, W.-S. see Seth, G.: Vol. 101, pp. 119–164.Hu, W.-S. see Wlaschin, K. F.: Vol. 101, pp. 43–74.

Author Index Volumes 101–108 361

Ingram, L. O., see Jarboe, L. R.: Vol. 108, pp. 237–261.

Jarboe, L. R., Grabar, T. B., Yomano, L. P., Shanmugan, K. T. and Ingram, L. O.: Developmentof Ethanologenic Bacteria. Vol. 108, pp. 237–261.

Jeon, Y. J., see Rogers, P. L.: Vol. 108, pp. 263–288.Jeppsson, M., see Hahn-Hägerdal, B.: Vol. 108, pp. 147–177.Jiang, J. see Lu, H. H.: Vol. 102, pp. 91–111.

Kamm, B. and Kamm, M.: Biorefineries—Multi Product Processes. Vol. 105, pp. 175–204.Kamm, M., see Kamm, B.: Vol. 105, pp. 175–204.Kaplan, D. see Velema, J.: Vol. 102, pp. 187–238.Karhumaa, K., see Hahn-Hägerdal, B.: Vol. 108, pp. 147–177.Kessler, F., Vidi, P.-A.: Plastoglobule Lipid Bodies: their Functions in Chloroplasts and their

Potential for Applications. Vol. 107, pp. 153–172.Konstantinov, K., Goudar, C., Ng, M., Meneses, R., Thrift, J., Chuppa, S., Matanguihan, C.,

Michaels, J. and Naveh, D.: The “Push-to-Low” Approach for Optimization of High-Density Perfusion Cultures of Animal Cells. Vol. 101, pp. 75–98.

Konstantinov, K. see Goudar, C.: Vol. 101, pp. 99–118.Kozlowski, G. see Felber, F.: Vol. 107, pp. 173–205.Kuyper, M., see van Maris, A. J. A.: Vol. 108, pp. 179–204.

de Laat, W. T. A. M., see van Maris, A. J. A.: Vol. 108, pp. 179–204.Laurencin, C. T. see Nair, L. S.: Vol. 102, pp. 47–90.Lawford, H. G., see Rogers, P. L.: Vol. 108, pp. 263–288.Lee, K. J., see Rogers, P. L.: Vol. 108, pp. 263–288.Lehrach, H. see Nordhoff, E.: Vol. 104, pp. 111–195Leisola, M.: Bioscience, Bioinnovations, and Bioethics. Vol. 107, pp. 41–56.Li, Z. see Patil, S.: Vol. 102, pp. 139–159.Liese, A., see Hilterhaus, L.: Vol. 105, pp. 133–173.Lu, H. H. and Jiang, J.: Interface Tissue Engineering and the Formulation of Multiple-Tissue

Systems. Vol. 102, pp. 91–111.Lund, H., see Schäfer, T.: Vol. 105, pp. 59–131.Lynd, L. R., see van Zyl, W. H.: Vol. 108, pp. 205–235.

Mabee, W. E.: Policy Options to Support Biofuel Production. Vol. 108, pp. 329–357.Mabee, W. E., see Chandra, R. P.: Vol. 108, pp. 67–93.Majka, J. and Speck, C.: Analysis of Protein–DNA Interactions Using Surface Plasmon

Resonance. Vol. 104, pp. 13–36.Malgras, N. see Schlaich, T.: Vol. 107, pp. 97–112.van Maris, A. J. A., Winkler, A. A., Kuyper, M., de Laat, W. T. A. M., van Dijken, J. P. and Pronk,

J. T.: Development of Efficient Xylose Fermentation in Saccharomyces cerevisiae: XyloseIsomerase as a Key Component. Vol. 108, pp. 179–204.

Matanguihan, C. see Konstantinov, K.: Vol. 101, pp. 75–98.Matsumoto, T. and Mooney, D. J.: Cell Instructive Polymers. Vol. 102, pp. 113–137.McBride, J. E., see van Zyl, W. H.: Vol. 108, pp. 205–235.Meneses, R. see Konstantinov, K.: Vol. 101, pp. 75–98.Merino, S. T. and Cherry, J.: Progress and Challenges in Enzyme Development for Biomass

Utilization. Vol. 108, pp. 95–120.Michaels, J. see Goudar, C.: Vol. 101, pp. 99–118.Michaels, J. see Konstantinov, K.: Vol. 101, pp. 75–98.

362 Author Index Volumes 101–108

Mikos, A. G. see Holland, T. A.: Vol. 102, pp. 161–185.Moghe, P. V. see Semler, E. J.: Vol. 102, pp. 1–46.Mooney, D. J. see Matsumoto, T.: Vol. 102, pp. 113–137.Muffler, K., see Becker, T.: Vol. 105, pp. 249–293.Mund, C. see Beier, V.: Vol. 104, pp. 1–11

Nair, L. S. and Laurencin, C. T.: Polymers as Biomaterials for Tissue Engineering and Con-trolled Drug Delivery. Vol. 102, pp. 47–90.

Nahmias, Y., Berthiaume, F. and Yarmush, M. L.: Integration of Technologies for HepaticTissue Engineering. Vol. 103, pp. 309–329.

Naveh, D. see Konstantinov, K.: Vol. 101, pp. 75–98.Ng, M. see Konstantinov, K.: Vol. 101, pp. 75–98.Nordhoff, E. and Lehrach, H.: Identification and Characterization of DNA-Binding Proteins

by Mass Spectrometry. Vol. 104, pp. 111–195.

Oeschger, M. P., Silva, C. E.: Genetically Modified Organisms in the United States: Implemen-tation, Concerns, and Public Perception. Vol. 107, pp. 57–68.

Olsson, L., see Otero, J. M.: Vol. 108, pp. 1–40.Otero, J. M., Panagiotou, G. and Olsson, L.: Fueling Industrial Biotechnology Growth with

Bioethanol. Vol. 108, pp. 1–40.Oxenbøll, K. M., see Schäfer, T.: Vol. 105, pp. 59–131.

Pan, X., see Chandra, R. P.: Vol. 108, pp. 67–93.Panagiotou, G., see Otero, J. M.: Vol. 108, pp. 1–40.Patil, S., Li, Z. and Chan, C.: Cellular to Tissue Informatics: Approaches to Optimizing

Cellular Function of Engineered Tissue. Vol. 102, pp. 139–159.Patocchi, A. see Gessler, C.: Vol. 107, pp. 113–132.Peattie, R. A. and Fisher, R. J.: Perfusion Effects and Hydrodynamics. Vol. 103, pp. 75–156.Peattie, R. A. see Fisher, R. J.: Vol. 103, pp. 1–73.Pedersen, S., see Schäfer, T.: Vol. 105, pp. 59–131.Peters, D.: Raw Materials. Vol. 105, pp. 1–30.Piret, J. see Goudar, C.: Vol. 101, pp. 99–118.Plissonnier, M.-L. see Schlaich, T.: Vol. 107, pp. 97–112.Poirier, Y. see van Beilen, J. B.: Vol. 107, pp. 133–151.Pörtner, R., see Becker, T.: Vol. 105, pp. 249–293.Poulsen, P. B., see Schäfer, T.: Vol. 105, pp. 59–131.Pronk, J. T., see van Maris, A. J. A.: Vol. 108, pp. 179–204.Puranen, T., see Viikari, L.: Vol. 108, pp. 121–145.Puskeiler, R., see Weuster-Botz, D.: Vol. 105, pp. 205–247.

Ragoussis, J. see Field, S.: Vol. 104, pp. 87–110Ranucci, C. S. see Semler, E. J.: Vol. 102, pp. 1–46.Reardon, K. F., see Becker, T.: Vol. 105, pp. 249–293.Reymond, J.-L. and Babiak, P.: Screening Systems. Vol. 105, pp. 31–58.Rogers, P. L., Jeon, Y. J., Lee, K. J. and Lawford, H. G.: Zymomonas mobilis for Fuel Ethanol

and Higher Value Products. Vol. 108, pp. 263–288.Romeis, J. see Sanvido, O.: Vol. 107, pp. 235–278.

Saddler, J. N., see Chandra, R. P.: Vol. 108, pp. 67–93.Salmon, S., see Schäfer, T.: Vol. 105, pp. 59–131.

Author Index Volumes 101–108 363

Sanvido, O., Romeis, J., Bigler, F.: Ecological Impacts of Genetically Modified Crops: TenYears of Field Research and Commercial Cultivation. Vol. 107, pp. 235–278.

Sassner, P., see Galbe, M.: Vol. 108, pp. 303–327.Sautter, C. see Schlaich, T.: Vol. 107, pp. 97–112.Schäfer, T., Borchert, T. V., Skovgard Nielsen, V., Skagerlind, P., Gibson, K., Wenger, K., Hatzack,

F., Dybdal Nilsson, L., Salmon, S., Pedersen, S., Heldt-Hansen, H. P., Poulsen, P. B., Lund,H., Oxenbøll, K. M., Wu, G. F., Høst Pedersen, H. and Xu, H.: Industrial Enzymes. Vol. 105,pp. 59–131.

Schlaich, T., Urbaniak, B., Plissonnier, M.-L., Malgras, N., Sautter, C.: Exploration and SwissField-Testing of a Viral Gene for Specific Quantitative Resistance Against Smuts andBunts in Wheat. Vol. 107, pp. 97–112.

Schrell, A., Bauser, H., Brunner, H.: Biotechnology Patenting Policy in the European Union– as Exemplified by the Development in Germany. Vol. 107, pp. 13–39.

Semler, E. J., Ranucci, C. S. and Moghe, P. V.: Tissue Assembly Guided via Substrate Bio-physics: Applications to Hepatocellular Engineering. Vol. 102, pp. 1–46.

Seth, G., Hossler, P., Yee, J. C., Hu, W.-S.: Engineering Cells for Cell Culture Bioprocessing –Physiological Fundamentals. Vol. 101, pp. 119–164.

Shanmugan, K. T., see Jarboe, L. R.: Vol. 108, pp. 237–261.Siika-aho, M., see Viikari, L.: Vol. 108, pp. 121–145.Silva, C. E. see Oeschger, M. P.: Vol. 107, pp. 57–68.Skagerlind, P., see Schäfer, T.: Vol. 105, pp. 59–131.Skovgard Nielsen, V., see Schäfer, T.: Vol. 105, pp. 59–131.Speck, C. see Majka, J.: Vol. 104, pp. 13–36Stahl, F., see Becker, T.: Vol. 105, pp. 249–293.

Thrift, J. see Konstantinov, K.: Vol. 101, pp. 75–98.Tsang, V. L. and Bhatia, S. N.: Fabrication of Three-Dimensional Tissues. Vol. 103, pp. 189–

205.

Udalova, I. see Field, S.: Vol. 104, pp. 87–110Ulber, R., see Becker, T.: Vol. 105, pp. 249–293.Urbaniak, B. see Schlaich, T.: Vol. 107, pp. 97–112.

Vehmaanperä, J., see Viikari, L.: Vol. 108, pp. 121–145.Velema, J. and Kaplan, D.: Biopolymer-Based Biomaterials as Scaffolds for Tissue Engineer-

ing. Vol. 102, pp. 187–238.Vidi, P.-A. see Kessler, F.: Vol. 107, pp. 153–172.Viikari, L., Alapuranen, M., Puranen, T., Vehmaanperä, J. and Siika-aho, M.: Thermostable

Enzymes in Lignocellulose Hydrolysis. Vol. 108, pp. 121–145.

Webster, T. J. and Ahn, E. S.: Nanostructured Biomaterials for Tissue Engineering Bone.Vol. 103, pp. 275–308.

Wenger, K., see Schäfer, T.: Vol. 105, pp. 59–131.Westermann, P., see Ahring, B. K.: Vol. 108, pp. 289–302.Weuster-Botz, D., Hekmat, D., Puskeiler, R. and Franco-Lara, E.: Enabling Technologies:

Fermentation and Downstream Processing. Vol. 105, pp. 205–247.Widmer, F.: Assessing Effects of Transgenic Crops on Soil Microbial Communities. Vol. 107,

pp. 207–234.Wingren, A., see Galbe, M.: Vol. 108, pp. 303–327.Winkler, A. A., see van Maris, A. J. A.: Vol. 108, pp. 179–204.

364 Author Index Volumes 101–108

Wlaschin, K. F. and Hu, W.-S.: Fedbatch Culture and Dynamic Nutrient Feeding. Vol. 101,pp. 43–74.

Wu, G. F., see Schäfer, T.: Vol. 105, pp. 59–131.

Xu, H., see Schäfer, T.: Vol. 105, pp. 59–131.

Yarmush, M. L. see Nahmias, Y.: Vol. 103, pp. 309–329.Yee, J. C. see Seth, G.: Vol. 101, pp. 119–164.Yomano, L. P., see Jarboe, L. R.: Vol. 108, pp. 237–261.

Zacchi, G., see Galbe, M.: Vol. 108, pp. 41–65.Zacchi, G., see Galbe, M.: Vol. 108, pp. 303–327.Zhang, C. see Goudar, C.: Vol. 101, pp. 99–118.van Zyl, W. H., Lynd, L. R., den Haan, R. and McBride, J. E.: Consolidated Bioprocessing for

Bioethanol Production Using Saccharomyces cerevisiae. Vol. 108, pp. 205–235.

Subject Index

Acetaldehyde 12Acetaldehyde dehydrogenases 26, 31Acetate 253Acetyl-CoA 24Actinobacillus succinogenes 25Alanine 255Alcohol dehydrogenase 2 (Adh2p) 26Ammonia fibre explosion (AFEX) 47, 50Ammonia recycle percolation (ARP)

method 50α-Amylases 304Anaerobiospirillum succiniciproducens 25Arabinose 147, 160Arabinose utilization, pathways 160–, S. cerevisiae 161

Baker’s yeast, CBP host 208Bio/catalytic refineries 299Biocatalysts, KO11/LY01, ethanologenic

240–, strain LY168, ethanologenic 243Bioethanol, demand 14–, production, one-step 205Bioethanol-related policy 350Biofuel production 331Biofuels 1, 329Biomass 67–, steam pretreatment 71Bioprocessing, consolidated 205Biorefineries 1, 8, 289Biotransformations, enzyme-based 281Brazil 12, 333Butanediol 25γ -Butyrolactone 25

Catalytic efficiency/productivity 106CBP yeast 228Cellobiohydrolase 121Cellobiose 46

Cellulases 67, 121–, fungal 251–, hydrolysis 84–, S. cerevisiae 211–, T. reesei 106–, thermostable 123Cellulolytic yeast 205Cellulose 67–, crystallinity 87–, enzymatic hydrolysis 122–, ethanol 10Cofactor dependence 164Corn 14Corn stover 52, 200–, hydrolysate, fed-batch fermentation

200Corynebacterium glutamicum, lysine 31

Diesters 10Differential gel-electropheresis (DiGE) 24Direct funding 329

Endoglucanase 121Energy demand 318Entner–Doudoroff pathway (EMP) pathway

28Enzymatic hydrolysis 41, 45Enzymes, cost 101–, discovery 106–, dosage 100–, mixtures, thermophilic/thermostable

131, 133–, production, economic 115–, recovery 117–, thermophilic/thermostable 121, 129Escherichia coli 237–, ethanologenic 240–, non-recombinant ethanologenic 246ETBE 10, 12

366 Subject Index

Ethanol 147, 237–, resistance 248Ethanol production 248, 263–, cellulose 10–, lignocellulosic materials 310Ethanolic fermentation, pentose-utilizing S.

cerevisiae 162Ethanologenicity,

metabolic/transcriptomic changes247

European Union 13, 337Evolutionary engineering, xylose 194Excise tax exemptions 329, 347

Fermentation 296–, trials, xyloseFine chemicals 282Fir 59Flowsheeting 309Fluxome 30Fluxomics 5, 29Formaldehyde 12Formic acid 46Forward metabolic engineering 18, 22Fuel cells 289Fumarate reductase subunit A (frdA) 25Funding programs, USA 343Fungal preparations, elevated temperatures

132Fusarium oxysporum 28

Galactose signaling pathway 26Genomics 18, 19Gluconate 281Glucose 25–, yield 61β-Glucosidase 108, 121Glutamate dehydrogenase 30Glycerol-3-phosphatase 26Glycolytic flux 169Glycose fermentation 263Glycosyl hydrolase family 61 109GRE3 deletion 165Growth media, cost effective 248

Haemophilus influenzae 19Hemicellulases, S. cerevisiae 218–, synergistic 111Hemicellulose 15, 67, 80–, content, hydrolysis 83

–, –, pretreatment 81–, hydrolysate 237, 250Hydrogen 289–, production 291Hydrolysates, fermentation 172Hydrolysis 67, 121, 296Hydrothermolysis (liquid hot-water

treatment) 505-Hydroxymethylfurfural (HMF) 46

Industrial biotechnology 2Industrial systems biology 5, 17–, bioethanol 32–, X-omics 15Inhibitor tolerance 171Isotope-coded affinity tag technology

(ICAT) 24

2-Keto-3-deoxy-6-phosphogluconateadolase (Eda) 24

Kyoto Protocol 13

Lactic acid 237, 252Levulinic acid 46Lignin 15, 67, 75–, enzymatic hydrolysis 78Lignocellulose 41, 121, 147– vs. starch 322Lignocellulosic biomass 97Lignocellulosic hydrolysates 180–, inhibitors 274Lignocellulosics 263Lignol organosolv process 60LY01, ethanol resistance 248LY168, ethanol production 244Lysine, Corynebacterium glutamicum

31

Mannheimia succiniciproducens 25Market drivers 3, 8Maxifuel 292Metabolic engineering 1, 263Metabolic flux 29Metabolomics 27Metagenomics 18Methane 289–, production 291MTBE 12Multidimensional protein identification

technology (MuDPiT) 24

Subject Index 367

NADPH 24

Organic acids, metabolic engineering279

Osmolyte stress 249

Penicillin 6Pentose-fermenting strains 170Pentose pathway enzymes 164Pentose phosphate pathway 28, 166Petroleum, economics 8–, prices 9Phage shock protein A (PspA) 24Pharmaceutical intermediates 282PHB 24Phenotypic phase plane (PhPP) analysis

20Phosphoketolase pathway (PKP) 30Pichia stipitis 5, 21–, xylitol dehydrogenase (XDH) 30Pine 58Pinus radiata, softwood 58Piromyces sp., xylose isomerase 31Policy 329–, bioethanol 350Poly-amides 25PPP, oxidative 167Pretreatment 295–, assessment 44–, methods 47, 69–, selection 102–, two-stage 60Process economics 311Process integration, enzyme requirements

104Production cost 3181,3-Propanediol (PDO), from corn 10Proteomics 5, 23Pyruvate 253

Redox enzymes 168Redox metabolism, engineering 167Redox restrictions 182Refineries, bio/catalytic 299Reforming 289Renewable fuel mandates 329Reverse metabolic engineering 18, 22

Saccharomyces cerevisiae 179,205

–, CBP host 208–, lignocellulosic hydrolysates 180Separation 296Severity factor, pretreatment 44Simultaneous saccharification and

fermentation (SSF) 45Softwood 57Sorbitol 281Spruce 59Starch 322Steam pretreatment 67–, biomass 71Strain stability 171Substrate selection 101Succinate 255Succinate dehydrogenase subunit A (sdhA)

25Succinic acid 25, 27Sugar fermentation, S. cerevisiae 210Sugar transport 163Sugarcane 15Surface area 85Synergy 107Systems biology 1SZ110 244

Tax exemptions 329TCA cycle 22–, intermediates 279Tetrahydrofuran 25Transcriptome analysis 5Transcriptomics 21Transhydrogenase 168Transportation fuel alternatives 11Trichoderma reesei, cellulases 20,

106

Vitamins 6

Wastewater treatment 297Wheat straw hydrolysate, batch

fermentation 199White biotechnology 2Wood, steam-pretreated 73

XI, S. cerevisiae 158XR/XDH, S. cerevisiae 159Xylitol 254Xylitol dehydrogenase (XDH) 30,

182

368 Subject Index

Xylose 26, 147, 149, 164Xylose fermentation 179, 263Xylose isomerase 31, 179, 186–, S. cerevisiae 187Xylose reductase 30, 182Xylose utilization, metabolic engineering

192–, pathways 158Xylose-isomerase expression, S. cerevisiae

198

Xylulokinase 30, 165Xylulose 164

Yeast 147–, cellulolytic 205Yield loss 99

Zymomonas mobilis 263–, genome sequence 278–, recombinant strains 265