basic dermatology by dr. haseeb ahmed
TRANSCRIPT
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BASIC DERMATOLOGYBASIC DERMATOLOGYHaseeb AhmedHaseeb Ahmed
2008-982008-98
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Dermatology Dermatology Skin (Integument)Skin (Integument) Largest tissueLargest tissue Vital functionsVital functions Skin failureSkin failure Shock, collapse, deathShock, collapse, death Steven Johnson syndromeSteven Johnson syndrome Burns Burns
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SKIN STRUCTURESKIN STRUCTURE
THREE LAYERS OF SKINTHREE LAYERS OF SKIN
EPIDERMISEPIDERMIS DERMISDERMIS SUBCUTANEOUS TISSUESUBCUTANEOUS TISSUE
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EPIDERMISEPIDERMISFOUR LAYERSFOUR LAYERS
STRATUM CORNEUMSTRATUM CORNEUM STRATUM GRANULOSUMSTRATUM GRANULOSUM STRATUM SPINOSUMSTRATUM SPINOSUM STRATUM BASALESTRATUM BASALE
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EPIDERMAL CELLSEPIDERMAL CELLS KERATINOCYTESKERATINOCYTES LANGERHAN’S CELLSLANGERHAN’S CELLS MELANOCYTESMELANOCYTES NEUROCEPTERSNEUROCEPTERS
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Epidermal proteinsEpidermal proteins
KeratinKeratin FillagrinFillagrin ProfillagrinProfillagrin
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DERMOEPIDERMAL DERMOEPIDERMAL JUNCTIONJUNCTION
THROWN INTO FOLDSTHROWN INTO FOLDS
DERMAL PAPPILLAEDERMAL PAPPILLAE
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DERMISDERMIS
TWO PARTSTWO PARTS
PAPPILLARY DERMISPAPPILLARY DERMIS
RETICULAR DERMISRETICULAR DERMIS
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DERMAL ELEMENTSDERMAL ELEMENTS
FIBRESFIBRES
COLLAGENCOLLAGEN ELASTINELASTIN RETICULINRETICULIN
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DERMAL ELEMENTSDERMAL ELEMENTS
CELLSCELLS LYMPHOCYTESLYMPHOCYTES MACROPHAGESMACROPHAGES HISTIOCYTESHISTIOCYTES PLASMACELLSPLASMACELLS MAST CELLSMAST CELLS BASOPHILSBASOPHILS
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APPENDAGESAPPENDAGES
HAIR FOLLICLESHAIR FOLLICLES SEBACEOUS GLANDSSEBACEOUS GLANDS SWEAT GLANDSSWEAT GLANDS NAILSNAILS
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Pilosebaceous unitPilosebaceous unit
Hair follicles (slanting position)Hair follicles (slanting position) Sebaceous glands (sebum )Sebaceous glands (sebum )
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Sweat glandsSweat glands
Apocrine (flexures)Apocrine (flexures) Eccerine Eccerine
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Functions of skin Functions of skin
Protective barrierProtective barrier Environment Environment Temperature regulationTemperature regulation Immune functionsImmune functions First line of defence First line of defence Immune cellsImmune cells
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Excretory functionsExcretory functions Waste materials, drugs, Waste materials, drugs, Electrolyte balanceElectrolyte balance Sweat Sweat Fluid balanceFluid balance Sweat Sweat
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Metabolic functionsMetabolic functions Metabolic processesMetabolic processes Store house of caloriesStore house of calories Hormonal functionsHormonal functions Vitamin D3 (Cholecalciferol)Vitamin D3 (Cholecalciferol) Vitamin E (Tocopherol)Vitamin E (Tocopherol)
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NeuroceptionNeuroception Receptors Dermoepidermal Receptors Dermoepidermal
junctionjunction Functions of modified structures Functions of modified structures
e.g.e.g. Hair, nailsHair, nails
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MACULEMACULEAltered skin color less than Altered skin color less than 1 cm1 cm
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PATCHPATCH Altered skin color more Altered skin color more than 1 cmthan 1 cm
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PAPULEPAPULEPalpable lesion less than 1 Palpable lesion less than 1 cmcm
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PLAQUEPLAQUE Palpable lesion more than 1 Palpable lesion more than 1 cmcm
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VESICLEVESICLEWater filled lesion less than Water filled lesion less than 1 cm1 cm
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BULLAEBULLAE Water filled lesion more Water filled lesion more than 1 cmthan 1 cm
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PUSTULEPUSTULE Pus filled lesion Pus filled lesion
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NODULENODULELesion 1 cm raised 1cm Lesion 1 cm raised 1cm broad broad
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Excoriation/Scratch Excoriation/Scratch marks/Erosion marks/Erosion
Discontinuity of outer three layers Discontinuity of outer three layers of epidermis of epidermis
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EXCORIATIONEXCORIATION
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Erosion/Scratch markErosion/Scratch mark
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Ulcer Ulcer
Discontinuity of outer three layers Discontinuity of outer three layers of epidermis with breakdown of of epidermis with breakdown of Dermoepidermal junctionDermoepidermal junction
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ULCERULCER
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ANNULAR LESIONANNULAR LESIONCircular lesion skin inside Circular lesion skin inside normal normal
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LINEAR LESIONLINEAR LESIONLesions in one lineLesions in one line
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HIVES (URTICARIAHIVES (URTICARIATransient erythematous Transient erythematous weals)weals)
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ERYTHEMAERYTHEMALocalized rednessLocalized redness
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ERYTHRODERMAERYTHRODERMARedness of 90% skin surface Redness of 90% skin surface areaarea
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PURPURAPURPURABleeding into skin Bleeding into skin
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HYPOPIGMENTATIONHYPOPIGMENTATIONSkin color less Skin color less
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HYPERPIGMENTATIONHYPERPIGMENTATIONDarker colorDarker color
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DEPIGMENTATIONDEPIGMENTATIONLoss of pigmentLoss of pigment
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Lichenification Lichenification Thickening of skin with prominent Thickening of skin with prominent
skin creasesskin creases
Hstologicaly outer 3 layers Hstologicaly outer 3 layers thickened but basement thickened but basement membrane remains normalmembrane remains normal
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TELENGIECTASIATELENGIECTASIADilated visible blood Dilated visible blood vesselsvessels
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ATROPHYATROPHY
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Scabies Scabies SARCOPTES SCABEIISARCOPTES SCABEII Burrow / vesicleBurrow / vesicle Genitals / fingure webs / toe websGenitals / fingure webs / toe webs Palms / solesPalms / soles
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SCABIESSCABIES
SARCOPTES SARCOPTES SCABEIISCABEII
BURROWBURROW
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Measles Measles
VIRAL INFECTIONVIRAL INFECTION Maculopapular eruptionMaculopapular eruption TrunkTrunk Febrile Febrile
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MEASLESMEASLES
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CHICKEN POXCHICKEN POXPolymorphic rashPolymorphic rashVARICELLA ZOSTERVARICELLA ZOSTER
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SYSTEMIC LUPUS SYSTEMIC LUPUS ERYTHEMATOSUSERYTHEMATOSUSBUTTER FLY RASHBUTTER FLY RASH
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Butterfly rashButterfly rash
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Facial erythema Facial erythema
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Raynaud’s Raynaud’s phenomenonphenomenon
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Photosensitivity Photosensitivity
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Photodermatitis Photodermatitis
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Cheiltis Cheiltis
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Oral ulcersOral ulcers
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Lupus hairLupus hair
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Livedoreticularis Livedoreticularis
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Purpura Purpura
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Acne Acne MULTIMORPHIC MULTIMORPHIC
LESIONSLESIONS
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