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    MODES OF MECHANICAL VENTILATION

    Mazen Kherallah, MD, FCCP

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    POINTS OF DISCUSSIONS

    | Advanced Basics:

    y Flow and Time

    y Limit and cycling

    y Rise Time

    y Volume vs Pressure Control

    | Mandatory Modes of Ventilation

    y Controlled Mandatory Ventilation (CMV or IPPV)

    | Triggered Modes of Ventilation

    y Continuous Positive Airway Pressure (CPAP)y Pressure Support Ventilation (PSV)

    | Hybrid Modes of Ventilation

    y Assist Control Mode (A/C)

    y Synchronized Intermittent Mandatory Ventilation (SIMV)

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    ADVANCED BASICS

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    RESPIRATORYCYCLE

    Inspiration

    Expiration

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    ExpInsp

    RELATIONSHIP BETWEEN TIDALVOLUME,

    INSPIRATORYTIME AND FLOW

    VT 1

    Ti a

    VT 2

    VT 3

    Time

    Volume

    Flow= 30 L/min

    Flow= 15 L/min

    Flow= 37.5 L/min

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    ExpExpInspInspInsp

    RELATIONSHIP BETWEEN TIDALVOLUME,

    INSPIRATORYTIME AND FLOW

    VT 1

    Ti a

    Time

    Volume

    Ti b Ti c

    Flow= 30 L/min

    Flow= 20 L/min

    Flow= 60 L/min

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    PRESSURE LIMITED BREATH

    Time

    Volume

    Pressure Limit

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    EXPIRATORYFLOW CYCLING

    Time

    Flow

    50%

    100%

    Flow Cycling

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    RISE TIME

    Time

    Flow

    Pressure

    Volume

    TI TE

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    MANDATORY, SPONTANEOUS AND TRIGGERED

    INSPIRATORYCYCLINGM

    S

    Tsynch

    M M

    M

    MM

    M

    M

    S

    M

    Tsupp Tsupp

    Tsupp Tsupp

    Tsupp

    Tsupp

    S

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    VOLUME CONTROLLED INFLATION

    Time

    Flow

    Pressure

    Volume

    TI TE

    Tidal Volume

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    If compliance decreases the pressure increases tomaintain the same Vt

    1 2 3 4 5 6

    SEC

    1 2 3 4 5 6

    PawcmH20

    50

    -20

    120

    120

    SEC

    INSP

    EXH

    FlowL/min

    VOLUME CONTROL BREATHS

    Decreased Compliance

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    VOLUME CONTROL WITH END-INSPIRATORY

    PAUSE

    Time

    Flow

    Pressure

    Volume

    TI TE

    Tidal Volume

    End Inspiratory Pause

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    PRESSURE CONTROLLED INFLATION

    Time

    Flow

    Pressure

    Volume

    TI TE

    Tidal Volume

    Rise Time

    Peak Inspiratory Flow

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    Inspiration Expiration

    0 1

    20

    00 1 2

    3

    -3

    0

    20

    0 21

    20

    00 1 2

    3

    -3

    0

    20

    0 2

    Inspiration Expiration

    Volume/Flow Control Pressure Control

    Time (s) Time (s)

    Paw

    Paw

    Pressure

    Volume

    Flow

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    TRIGGERED MODES OF

    VENTILATIONCPAP and PSVV

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    SPONTANEOUS BREATHING

    Time (sec)

    Flow

    (L/m)

    Pressure(cm H2O)

    Volume

    (mL)

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    PRESSURE SUPPORTVENTILATION

    (PSV)

    Time (sec)

    Flow

    (L/m)

    Pressure(cm H2O)

    Volume

    (mL)

    Set PS

    Level

    Flow

    Cycling

    Better Efforts

    Longer Inspiration

    Patient Triggered, Flow Cycled, Pressure limited Mode

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    CPAP+PSV

    Time (sec)

    Flow

    (L/m)

    Pressure

    (cm H2O)

    Volume

    (mL)

    Set PS

    Level

    Flow

    Cycling

    Patient Triggered, Flow Cycled, Pressure limited Mode

    CPAP Level

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    TRIGGERED MODES OFVENTILATION

    PRESSURE SUPPORTVENTILATION

    Control Trigger Limit Target Cycle

    Pressure Patient Pressure Flow

    Patient Triggered Flow Cycled Ventilation

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    PRESSURE ORVOLUME-TARGETED

    VENTILATION

    | Full to partial ventilatory support

    | Augments the patients spontaneous VT

    | Decreases the patients spontaneous

    respiratory rate

    | Decreases patient WOB by overcomingthe resistance of the artificial airway,

    vent circuit and demand valves

    | Allows patient control of TI, Vm I, f and

    VT

    | Set peak pressure| Prevents respiratory muscle atrophy

    | Facilitates weaning

    | Improves patient comfort and reduces

    need for sedation

    | May be applied in any mode that allows

    spontaneous breathing, e.g., VC-SIMV,

    PC-SIMV

    | Requires consistent

    spontaneous ventilation

    | Patients in stand-alone

    mode should have back-up

    ventilation| VT variable and dependant

    on lung characteristics and

    synchrony

    | Low exhaled VE

    | Fatigue and tachypnea if PS

    level is set too low

    Advantages Disadvantages

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    MANDATORY MODES OF

    VENTILATIONCMV or IPPV

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    MANDATORYMODES OFVENTILATION

    CMV

    Control Trigger Limit Target Cycle

    Pressure

    Or

    Volume

    Time Time

    Time Triggered Time Cycled Ventilation

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    CONTROL MODE

    (PRESSURE-TARGETEDVENTILATION)

    Flow

    (L/m)

    Pressure

    (cm H2O)

    Volume

    (mL)

    Time Triggered, Pressure Limited, Time Cycled Ventilation

    Time (sec)

    Time CyclingSet PC Level

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    CONTROL MODE

    (VOLUME-TARGETEDVENTILATION)

    Flow

    (L/m)

    Pressure

    (cm H2O)

    Volume

    (mL)

    Time Triggered, Flow Limited, Volume Cycled Ventilation

    Time (sec)

    Preset VTVolume Cycling

    Time Cycling

    Dependent on

    CL& Raw

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    PRESSURE ORVOLUME-TARGETED

    VENTILATION

    | Decreases the

    work of breathing

    (WOB)

    | Helps maintain a

    normal PaCO2

    | Not able to assist the

    ventilator

    Advantages Disadvantages

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    HYBRID MODES OF

    VENTILATIONSIMV and A/C

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    HYBRID MODES OFVENTILATION

    A/C

    Control Trigger Limit Target Cycle

    Pressure

    Or

    Volume

    Time

    Or

    Patient

    Time

    Time or PatientTriggered Time Cycled

    Ventilation

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    ASSISTED MODE

    (VOLUME-TARGETEDVENTILATION)

    Flow

    (L/m)

    Pressure

    (cm H2O)

    Volume

    (mL)

    Patient Triggered, Flow limited, Volume Cycled Ventilation

    Time (sec)

    Preset peak Flow

    Time Cycling

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    ASSISTED MODE

    (PRESSURE-TARGETEDVENTILATION)

    Flow

    (L/m)

    Pressure

    (cm H2O)

    Volume

    (mL)

    Patient Triggered, Pressure Limited, Time Cycled Ventilation

    Time (sec)

    Time CyclingSet PC Level

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    PRESSURE ORVOLUME-TARGETED

    VENTILATION

    | Decreases the

    work of breathing

    (WOB)

    | Allows patients to

    regulate

    respiratory rate

    | Helps maintain anormal PaCO2

    |Alveolar

    hyperventilation

    Advantages Disadvantages

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    HYBRID MODES OFVENTILATION

    SIMV/PS

    Breath

    Type

    Control Trigger Limit Cycle

    Mandatory Pressure

    Or

    Volume

    Time

    Or

    Patient

    Time

    Spontaneous Pressure Patient Pressure Flow

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    SIMV

    (VOLUME

    TARGETED

    VENTILATION

    )

    Flow

    (L/m)

    Pressure

    (cm H2O)

    Volume

    (mL)

    Spontaneous Breaths

    M M M

    Time (sec)

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    SIMV+PS

    (VOLUME

    TARGETED

    VENTILATION

    )

    Flow

    (L/m)

    Pressure

    (cm H2O)

    Volume

    (mL)

    MTsuppTsynch

    Set PS Level

    Flow-cycled

    Time (sec)

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    SIMV + PS

    (PRESSURE

    -TARGETED

    VENTILATION

    )

    Flow

    (L/m)

    Pressure

    (cm H2O)

    Volume

    (mL)

    Tsupp

    Tsynch

    Time CycledFlow-cycled

    Tsynch

    Set PC Level Set PS Level

    Time (sec)

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    HYBRID MODEVENTILATION: SUPPRESSION

    Time (sec)

    Flow

    (L/m)

    Pres

    sure

    (cmH2O)

    Cycles

    M Tsupp MMTsupp

    M M

    Tsupp Tsupp

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    HYBRID MODEVENTILATION: SYNCHRONIZATION

    (SIMV+PSV)

    Time (sec)

    Flow

    (L/m)

    Pressure

    (cm H2O)

    Cycles

    Triggered window for

    supported breaths

    Triggered window for

    synchronized breaths

    Mandatory Cycle Time

    M Tsupp Tsynch M Tsynch Tsupp

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    SIMV

    | Maintains respiratory

    muscle strength by

    avoiding muscle

    atrophy

    | Decreases mean

    airway pressure

    | Facilitates ventilator

    discontinuation weaning!

    | When used for

    weaning, may be done

    too quickly and cause

    muscle fatigue

    | Mechanical rate and

    spontaneous rate may

    asynchronous causing

    stackingy May cause

    barotrauma or

    volutrauma

    Advantages Disadvantages

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    ALL MODES TABLES

    Mandatory Modes of Ventilations

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    Mandatory Modes of Ventilations

    Mandatory breaths

    Inspiratory cycling Time Time Time Time

    Control Volume Volume Volume (Pressure)

    Target/Limit - Pressure-limited Volume-targeted

    Feeadback - - Intra-breath Inter-breath

    Expiratory cycling Time Time Time Time

    Triggered Breaths

    Types None None None None

    Supported Breaths

    Control - - - -

    Target - - - -

    Feedback - - - -

    Expiratory Cycling - - - -

    Spontaneous Breaths

    During mandatory inspirationNot

    accommodated

    Not

    accommodated

    Not

    accommodatedAccommodated

    OtherwiseNot

    accommodatedAccommodated

    Not

    accommodatedAccommodated

    Synonyms

    IPPV (Draeger)

    ControlledMandatory

    Ventilation

    IntermittentMandatory

    Ventilation

    IPPV (Draeger):trigger off,

    autoflow off

    IPPV (Draeger):trigger off,

    autoflow on

    Triggered Modes of Ventilations

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    Triggered Modes of Ventilations

    Mandatory breaths

    Inspiratory cycling - - -

    Control - - -

    Target/Limit - - -

    Feeadback - - -

    Expiratory cycling - - -

    Triggered Breaths

    Types Supported breaths Supported breaths Supported breaths

    Supported Breaths

    Control Pressure (Pressure) (Pressure)

    Target -- Volume-targeted Flow and Volume

    Feedback -- Inter-breath Intra-breath

    Expiratory Cycling Flow Flow Flow

    Spontaneous Breaths

    During mandatory inspiration - - -

    Otherwise - - -

    Synonyms

    Assisted Spontaneus Breathing

    (Draeger)

    Spontaneous Mode (Hamilton,

    Puritan Bennet)

    Pressure Support (MaquetPressure Support Ventilation

    (Viasys)

    CPAP (Respironics)

    Volume Support

    (Maquet, Puritan-

    Bennett)

    Propotional Assist

    Ventilation,

    Proportional Pressure

    Suport (Draeger)

    Propotional AssistVentilation Plus

    (Puritan-Bennet)

    Hybrid Mode: Assist Control

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    Hybrid Mode: Assist Control

    Mandatory breaths

    Inspiratory cycling Time or trigger Time or trigger Time or trigger

    Control Volume Pressure (Pressure)

    Target/Limit - - Volume-targeted

    Feeadback - - Inter-breath

    Expiratory cycling Time Time Time

    Triggered Breaths

    Types Mandatory pattern Mandatory pattern Mandatory pattern

    Supported Breaths

    Control - - -

    Target - - -

    Feedback - - -

    Expiratory Cycling - - -

    Spontaneous Breaths

    During mandatory inspiration Not accommodated Accommodated Accommodated

    Otherwise - - -

    Synonyms

    IPPVASSIST (Draeger)

    Synchronized cCntrolled

    Mandatory Ventilation

    (Hamilton)

    Volume Control (Maquet)VCV-A/C (Puritan-Bennett,

    Respironics)

    Volume A/C (Viasys)

    BIPAPASSIST (Draeger)

    P-CMV (Hamilton)

    Pressure Control

    (Maquet)

    PCV-A/C (Puritan-Bennett, Respironics)

    Pressure A/C (Viasys)

    Adaptive Pressure

    Ventilation CMV

    PRVC (Maquet)

    VC+A/C (Puritan-

    Bennet)PRVC A/C (Viasys)

    IPPV Assist Autoflow

    (Draeger)

    Hybrid Mode: Synchronized Intermittent Mandatory Ventilation

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    Hybrid Mode: Synchronized Intermittent Mandatory Ventilation

    Mandatory breaths

    Inspiratory cycling Time or trigger Time or trigger Time or trigger

    Control Volume Pressure (Pressure)

    Target/Limit - - Volume-targeted

    Feeadback - - Inter-breath

    Expiratory cycling Time Time Time

    Triggered Breaths

    TypesMandatory and

    supported pattern

    Mandatory and supported

    pattern

    Mandatory and

    supported pattern

    Supported Breaths

    Control Pressure Pressure Pressure

    Target - - -

    Feedback - - -

    Expiratory Cycling Flow Flow Flow

    Spontaneous Breaths

    During mandatory inspiration Not accommodated Accommodated Accommodated

    Otherwise Only if support is off Only if support is off Only if support is off

    Synonyms

    SIMV (Draeger, Hamilton)

    SIMV (VC)+PS (Maquet)

    VCV-SIMV (Puritan-Bennett, Respironics)

    Volume SIMV (Viasys)

    P-SIMV (Hamilton)

    SIMV(PC)+PS

    (Maquet)

    PCV-SIMV (Puritan-Bennett, Respironics)

    Pressure SIMV

    (Viasys)

    SIMV+Autoflow

    Adaptive Pressure

    Ventilation SIMV

    (Hamilton)SIMV (PRVC)+PS

    (Puritan-Bennett)

    PRVC SIMV (Viasys)

    Hybrid Mode: Bi-Level Ventilatio

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    Mandatory breaths

    Inspiratory cycling Time or trigger Time or trigger Time or trigger Time or trigger

    Control Pressure Pressure Pressure Pressure

    Target/Limit - - - -

    Feeadback - - - -

    Expiratory cycling Time or trigger Time or trigger Time or trigger Time or trigger

    Triggered Breaths

    InteractionMandatory andsupported

    Mandatory pattern andsupported

    Mandatory andsupported

    Mandatory andsupported

    Supported Breaths

    Control Pressure Pressure Pressure Pressure

    Target - - - -

    Feedback - - - -

    Expiratory Cycling Flow Flow Flow Flow

    Spontaneous Breaths

    During mandatoryinspiration

    Accommodated

    Trigers suuport to PEEP+Psupport If

    this>Phigh (Hamilton DuoPAP)

    Plow+Psupport If this>Phigh (Hamilton

    APRV)

    PEEPL+PsuppIf this>PEEPH(Puritan-Bennett)

    Triggers support toPRES HIGH + PSV if

    Thigh PSV is activated

    Tigger support to

    PSV above PHigh

    Otherwise Triggers support

    Triggers support to PEEP+Psupport(Hamilton) DuoPAP)

    Plow+Psupport (Hamilton APRV)

    PEEPL+Psupp (Puritan-Bennett)

    Triggers support to

    PREDSLOW=PSV

    Triggers support to

    PSV above PEEP

    SynonymsBIPAP

    (Draeger)

    DuoPAP/APRV (Hamilton)

    BiLevel (Puritan-Bennet)

    APRV/Bi-phasic

    (Viasys)Bi-vent (Maquet)

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    THANK

    YOU