berkeley special adverti sing supplement visionary ......building. “it takes intelligence,...

The winners (l-r):

Danielle ApplestoneOther Machine Co.

stephen isaacsAduro Biotech

emilie MazzacuratiFour Twenty Seven Climate Solutions

Berkeley

AwardsVisionary

2016

Special advertiSing SupplementSeptember 30, 2016

At Berkeley Rep

The new Peet’s Theatre at Berkeley rep is a fitting site for the presentation of the 2016 Berkeley Visionary

Awards. The Theatre represents Berkeley’s innovative culture – in the arts, science and entrepreneurship.

2 Advertising supplement berkeley | visionary awards 2016 sAn FrAncisco Business TiMes september 30, 2016 berkeley | visionary awards 2016 Advertising supplement 3

Berkeley is the place. Visionaries start here.

T he Visionary Awards give us an occasion to share why there is such energy in Berkeley these days: The people!

You feel their energy in our business accelerators, new places to work and the expanding West Berkeley research labs.

You hear their energy in the animated conversations at university incubators and tech launch pads. People are gathering in cafe, bars, and breweries to meet friends and to network and share ideas that lead to exciting ventures. You recognize it in the vitality of our arts scene.

We’ve said it before: Berkeley is brilliant and booming.

Cutting edge research Berkeley is home to UC Berkeley and the Berkeley Lab. Together they employ or

train more than 45,000 people. These researchers and students are making exciting discoveries and launching businesses across the community. Together the City of Berkeley, the Berkeley Chamber and a network of university and lab initiatives are collaborating to help these firms grow and advance here.

Superb Quality of lifeBerkeley enjoys big city amenities with all of the best parts of small town life:

Distinctive retail destinations, tree-lined streets, world-class arts, award-winning food, walkable neighborhoods, easily accessible transit– served by three BART sta-tions – and a great bike infrastructure.

We hope you share the energy these awards inspire and that even more visionar-ies make Berkeley their home.

Dee Williams-Ridley, City Manager, City of Berkeley

Welcome to the 2016 Berkeley Visionary Awards

T he Berkeley Chamber is proud to present our fourth annual Berke-ley Visionary Awards. This year we are showcasing local Berkeley businesses’ strength in biopharma, climate science and the makers movement. Our awardees are all businesses that have consciously

chosen to locate and grow in Berkeley, recognizing the wealth of talent avail-able and the visionary zeitgeist of our city.

We at the Chamber have always known that Berkeley is a place for vision-aries. We created these awards to honor entrepreneurs who want to change the world we live in and recognize that Berkeley is a great place to make it happen.

We want to recognize David Teece, professor at UC Berkeley and founder of the Berkeley Research Group, who was excited about our concept from the beginning and has generously underwritten the Visionary Awards ever since.

The Visionary Awards event, together with the innovators it honors, owes a great deal to the champions of public-private partnership whose efforts po-tentiate what Berkeley has to offer. We are proud to thank our partners at the City of Berkeley, UC Berkeley, the Lawrence Berkeley National Laboratory, as well as Wareham Development, Sutter Health Alta Bates Medical Center and the Bayer Corporation.

As the ‘Independent Voice for Business in Berkeley’, the Chamber welcomes you to the 2016 Berkeley Visionary Awards.

Polly Armstrong, CEO/Community RelationsKirsten MacDonald, CEO/Operations

Celebrating Berkeley’s innovative leaders

T he Berkeley Visionary Awards were created to honor those individuals with the imag-ination and persistence to innovate in the city of Berkeley. With the unique attributes

of the university, the national laboratory and our creative private sector, entrepreneurs are now taking advantage of these rich resources to launch innova-tive companies, create high-quality jobs and generate technologies that have global impact.

The Berkeley Chamber conceived and launched the visionary awards to recognize and honor those

entrepreneurs who have overcome barriers, pursued dramatic change and made our city, our region and hopefully the world a better place to live.

The Chamber is a partner with the City of Berke-ley, UC Berkeley and the Berkeley National Lab and together we encourage talent trained in Berkeley to stay in Berkeley, hire in Berkeley and grow their busi-nesses in Berkeley.

This year one of our awardees is transforming manufacturing through unique and accessible desk-top production tools, another is helping major cor-

porations monitor and manage risk as climate change begins to impact businesses across the globe, and a third is another UC Berkeley alumni who has brought his company public and is focusing on a breakthrough approach in cancer treatment.

We had many exciting companies from which to choose and we are proud to present these three as our 2016 winners.

Polly Armstrong, CEO/Community RelationsKirsten MacDonald, CEO/Operations

about the Berkeley Visionary awards

From Berkeley’s City managerFrom the Berkeley ChamBer

Stephen Isaacs of Aduro Biotech; Danielle Applestone ofOther Machine Co.; Kirsten MacDonald, Berkeley Chamber; Dee Williams-Ridley, Berkeley City Manager; Emilie Mazzacurati, of Four Twenty Seven Climate Solutions; and Polly Armstrong, Berkeley Chamber.

JOIN US: www.career.bayer.us

At Bayer, our focus on life sciences enables us to tackle some of the biggest challenges of our time –

in humans, animals and plants.

For over 100 years in Berkeley, we’ve been building productive and lasting partnerships to advance new and innovative

treatments and strengthen our community.

INNOVATION COMES FROM CHALLENGING THE WAY WE DO THINGS TODAY

StorieS by Carol PiaSente Cover Photo by Paolo veSCia PubliCation deSign by Carol Collier

paolo

vescia


A duro Biotech Inc. was pursuing the development of cancer immunotherapies far before it was in vogue. “We were in the immunotherapy field when many people were skeptical and investors in this field of re-

search were scarce,” says CEO Stephen Isaacs. “But we always believed in the potential of immunotherapies to transform the cancer care landscape, and it seems the data is now catching up to our vision.”

Products developed from Aduro’s LADD, STING Pathway Activator and B-select monoclonal antibody platforms are designed to ignite the immune system to mobilize and attack tumors.

“These last two years have been banner years for Aduro,” says Isaacs. “We completed a successful IPO where we raised approximately $125 million and have reported multiple clinical trial data.”

Fundraising strategy is very important to every biotech company, says Isaacs. “Even prior to the IPO, we were for-tunate to be backed by very supportive private investors and venture capitalists who share our vision to change the oncology landscape as immunotherapy pioneers.”

“Now that we are a publicly traded company, we continue to receive strong support from leading in-vestors who believe our science and research could really transform how cancer patients suffering from the deadliest tumors are treated.”

In addition to strong investor support, Aduro has license agreements with Janssen and a collaboration with Novartis that provide ongoing funding as specific milestones are reached. As of June, Aduro could bank on $397 million in cash and cash equivalents.

Having a strong cash position enables Aduro to move forward with the development of its potentially life-saving products to treat a variety of can-cers and other autoimmune and infectious diseases.

The partnerships with Janssen and Novartis allow Aduro’s technology to be developed in collaboration with highly expe-rienced large pharmaceutical partners. With last year’s acqui-sition of BioNovion, a privately held Dutch company, Aduro gained a unique monoclonal antibody program as well as lead-ing management who originally developed the drug Keytruda.

“We now have three innovative approaches to stimulate the immune system under one company, a fact we believe is rare and provides a distinct advantage for a biotechnology company of our size,” says Isaacs.

The growing company, which now numbers 130 employ-ees, made a conscious decision to stay in Berkeley when it became apparent they needed a larger building.

“It takes intelligence, confidence and guts to do what we do, and I can’t think of a city that better epitomizes these qualities than Berkeley. In fact, some of the research that launched my career started from some experiments that were conducted in a garage in Berkeley,” says Isaacs.

Aduro recently moved into one half of a new 110,000-square-foot building that’s part of Wareham’s 18-acre, 17-building Aquatic Park Center research cam-pus in West Berkeley. The plan is to fully occupy the en-tire property by January 2018.

“The Bay Area is a strong biotech hub,” says Isaacs. “Through our relationship with UC Berkeley, we have a tremendous pool of scientific talent from which to recruit, and through our Immunotherapeutics and Vaccines Research Initiative (IVRI) collaboration with the university, we have a direct line to the in-novative research ongoing at the school.”

“We always believed in the potential of

immunotherapies to transform the cancer care landscape, and it seems the data is now catching

up to our vision.”

Visionary award winner

aduro Biotech:Immunotherapy to fight cancer

Stephen Isaacs,CEO, Aduro

T his year’s Visionary Award winners are car-rying on Berkeley’s long tradition of putting their intellect, their passion and their willing-ness to work tackling big issues head on.

Whether it’s providing strategies for adapting to cli-mate change, laying the foundation for the next wave of manufacturing or treating cancer, this generation of Berkeley entrepreneurs is engaging with market forces to make the world a better place.

“There’s a through-line between the disruptive social change Berkeley played a role in during the last century and the ways in which we are disruptive today,” says Mi-chael Caplan, manager of the City of Berkeley’s Office of Economic Development (OED).

“Today’s students and researchers, engineers and entrepreneurs are applying outside-the-box thinking

to solving critical health problems and environmental challenges,” says Caplan. “Inspired to make the world a better place, they’re starting new companies to realize their dreams and commercialize their inventions and products.”

Rhonda Shrader, director of the Berkeley-Haas Entrepreneurship Pro-gram at UC Berkeley, agrees: “People in Berkeley want to find meaningful problems to solve, whether they’re students or entrepreneurs. It’s in their DNA. As innovators, they scratch the surface just a little deeper to find out what’s really meaningful and what will have a real, positive impact.”

Emilie Mazzacurati, founder and CEO of Four Twenty Seven, a climate research and ad-aptation firm, finds that “by tradition and culture and

because of who lives here, Berkeley startups tend to be more mission-driven with a social or environmental purpose.”

Four Twenty Seven was part of the Berkeley-Haas accelerator and Maz-zacurati likes that people in Berkeley “find it normal to be an entrepre-neur. You don’t feel like a complete alien when you talk to your friends.”

Berkeley’s entrepreneurs are bolstered by a wealth of resources for start-ups and businesses that are bit further along in their growth trajectory. UC Berkeley-backed incubators and accelerators work hand in hand with the OED to help businesses get off the ground and reach the next stage in terms of strategy, working with clients and bringing products to market.

Adity Tibrewala, a recent Cal grad and community manager of Berke-ley’s Impact Hub, says, “People in Berkeley are rebels, in the best sense of the word.”

The Impact Hub, a coworking space located downtown in the David Bower Center, just steps from the university campus and Berkeley BART, was itself an innovative social experiment.

Founded in 2009, following a successful launch of the model in Europe, Impact Hub Berkeley was “the American test kitchen,” says Tibrewala. “If it worked here, the concept of a shared workspace for people who had a sim-

ilar mindset toward social entrepreneurship could be expanded elsewhere.” And clearly, it did work – there are now Impact Hubs in Oakland, San

Francisco and Washington, D.C., in addition to a network of hubs in more than 81 cities across the globe serving some 15,000 members.

Businesses that got their start at Impact Hub Berkeley include Alba Light, which makes highly efficient LED lighting; Senda Athletics, maker of fair trade soccer balls; and TaroWorks™, which created a suite of mobile data collection and analytical tools designed to put data directly in the hands of users.

Impact Hub focuses on social enterprises, but impact-oriented busi-nesses can be found in each of Berkeley’s three other major cowork facili-ties (NextSpace, WeWork and Sandbox Suites).

WeWork occupies all seven floors of 2120 University Avenue and houses dozens of companies. Among them, VIA Analytics, a SkyDeck alum that works to improve public transit through innovative technology and data solutions. TrulyMad.com also operates its social startup at WeWork Berke-ley. Trulymad raises money for nonprofits by selling lifestyle brands.

Located just across the street from the Downtown Berkeley BART sta-tion, Next Space is another active cowork community that includes so-cially conscious enterprises. ProjectVision which uses behavioral analytics and mobile technology to help patients prevent obesity, is one example of their many tech and cause-related companies.

a culture of innovation with a social edge

“People in Berkeley want to find

meaningful problems to solve, whether

they’re students or entrepreneurs.

It’s in their DNA.” Rhonda Shrader,

Director, Berkeley-Haas Entrepreneurship Program,UC

Berkeley

Sharing ideas at Impact Hub Berkeley, the first U.S. location of this global network of 81 coworking spaces serving social enterprise.

Introduced by John HearstProfessor emeritus, UC Berkeley College of Chemistry

paolo vescia

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to society faster than it has been done traditionally.

Multinationals, small businesses and startups have all licensed Berkeley Lab technologies in fields ranging from biotechnology and nanotechnology to energy efficiency and semiconductor manufacturing. Companies as diverse as Exogen (2014 Berkeley Visionary), PolyPlus Batteries (2013 Berkeley Vi-sionary), Lygos and Newomics, among 40 in total, have been founded on Berkeley Lab technology.

The Berkeley Lab is even innovat-ing innovation. Cyclotron Road is the lab’s new approach to “spin in” startups. These nascent ventures have potentially

game-changing energy technologies that fall between further academic re-search funding and venture investment. Through Cyclotron Road, Berkeley Lab provides salaries to these startup found-ers and access to the lab’s research tools, expertise and networks. Cyclotron Road brings in people inventing breakthrough technology and helps them move their product to market.

“It is not spinning something out of the lab, it is spinning people into the lab,” says Director Mike Witherell about Cyclotron Road. “It is an extremely com-petitive program that attracts the best and brightest from around the nation.”

Developed first in Berkeley, other na-tional laboratories are attempting to rep-licate this powerful model.

B erkeley and the wider Bay Area are direct bene-ficiaries of the intellectual power of two of the world’s most respected research institutions: The University of California, Berkeley and the Law-

rence Berkeley National Laboratory.Not only do these two institutions attract top research,

engineering, academic and management talent from across the globe, they also drive the creation of businesses based on novel technologies. These companies are attracting investment and interest worldwide to Berkeley and the broader East Bay.

More than a third of venture funds on earth are invested in the Bay Area, according to the Berkeley-Haas Entrepre-neurship Program.

“Capital is coming to Berkeley in a very serious way. It’s an indicator of the startup opportunities here,” says Caro-line Winnett, executive director of SkyDeck, UC Berkeley’s startup accelerator.

SkyDeck success stories include Eko Devices, which sells a “smart” stethoscope that enables physicians to compare results with a huge cloud database. Jill Fuss (2015 Berke-ley Visionary), a Berkeley Lab scientist, heads CinderBIO. CinderBIO produces a new class of ultra-stable enzymes as biodegradable alternatives for harsh industrial chemicals.

These are just two recent examples of dynamic startups that are propelling Berkeley’s innovation growth.

That growth is likely to accelerate. UC Berkeley’s Office of Intellectual Property and Industry Research Alli-ances has generated more than $235 million in licensing revenue, and the campus is expanding efforts to inte-grate tech transfer into many research and educational activities.

“The advent of numerous startup resources in and around UC Berkeley and the Berkeley Lab, has catapulted the Berkeley community into the planet’s top-tier of innovation ecosys-

tems,” said Mike Cohen, director of Innovation Ecosystem Development at UC Berkeley’s Office of Technology Li-censing. “There are growing resources off campus such as The House and Tech Futures and a growing community of cowork facilities. Campus-related infrastructure now includes SkyDeck, the CITRIS Foundry and the QB3 East Bay Innovation Center.”

The QB3 East Bay Innovation Center (QB3-EBIC) in West Berkeley is a launching pad for pioneers like Cari-bou Biosciences, whose CRISPR gene-editing technology is gaining worldwide attention. Growing at a fast clip, Caribou remains in the heart of Berkeley’s bioscience cluster. While QB3-EBIC tenant Zephyrus Biosciences was acquired this year by a Minnesota biotech, most QB3-EBIC tenants choose to stay and grow in Berkeley and the East Shore research cluster where they enjoy strong sup-port and collaboration.

At the Berkeley Lab, the Innovation and Partnerships Office (IPO) works to transition technologies to the mar-ketplace. IPO focuses on integrating the Berkeley Lab with local, regional and national commercialization ac-tivity – helping to drive technology solutions from the lab

Powerhouse institutions generate innovation

“UC Berkeley has the 2nd highest percentage of industry-sponsored

research when compared to other research

institutions.”

UC Berkeley’s Office of Intellectual Property & Industry

Research Alliances

Researcher Jinghua Guo at the Lawrence Berkeley National Laboratory’s Joint Center for Artificial Photosynthesis site doing battery research.

Researcher Leslie Silva studies samples in Trent Northern’s lab at the Joint Genome Institute, Lawrence Berkeley National Laboratories.

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The berkeley lab at a glance

13Nobel Prizes

13National Medal of Science recipients

$700 MContributed to the local

economy annually

3,304Number of employees

$811 MFY 2015 budget

Mike Witherell, Director, The Lawrence Berkeley National Lab; keynote speaker at the

2016 Berkeley Visionary Awards

A s a vital engine of Califor-nia’s economy, UC Berkeley has been generating start-ups at an ever-faster rate in

recent years and stimulating more and more companies and jobs, according to a study released by the Bay Area Coun-cil Economic Institute.

Counting back to 1968, the campus has spawned 260 STEM-related start-ups, 99 of which were still active as of June 2015, the study showed. About half of the active startups are in the infor-mation technology field.

Startups are important, according to the study, because in the vast ma-jority of cases they locate in California, usually close to the founding faculty member’s campus or to the campus from which the founding entrepre-neur/CEO graduated. They also tend to grow in the communities where they are founded.

“The Bay Area Council study val-idates the Berkeley startup story,” says Michael Caplan, manger of the city’s

Office of Economic Development. “We’ve worked with the university and its network of incubators and accel-erators to ensure the new companies started here have a place to continue to grow and expand in Berkeley.”

Berkeley and San Diego lead all 10 UC campuses in startup activity. Alto-gether researchers and entrepreneurs at UC have generated hundreds of new companies employing tens of thousands of Californians and contributing more than $20 billion to the state’s economy.

The study counted some 38,800 jobs in UC-affiliated companies, and found that the companies indirectly support 108,460 other jobs across a wide range of industries and incomes.

In analyzing startup formation at each campus, the study found that re-search across the university has formed the basis for the startups.

The report reflects just how essential UC Berkeley and the entire University of California system are in fueling the state’s innovation economy.

Berkeley and UC startups are vital to California’s economy

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DOWNTOWNBERKELEY.COM

A vibrant mix of culture, food, arts,and ideas where inspiration thrives

The “Independent Voice for Business,” the Berkeley Chamber supports its business mem-bers and the economy of Berkeley by provid-ing education, advocacy and connection.

A key role of the Chamber is to convene and help build relationships among business leaders, the city and the community.

While chambers of commerce are local institutions with a long history, the Berkeley Chamber is an organization, independent from the national chamber, that is reinvent-ing what it means to be a voice for business in the 21st century.

The Visionary Awards are one example of the Berkeley Chamber’s initiatives to connect its legacy of business leadership with a new generation of change makers.

about the Berkeley ChamberJoin the Chamber!

The Berkeley Chamber offers many specific benefits:

Networking: Multiple opportunities for networking with East Bay business and political leaders.Education: Seminars on current topics of interest to business.Advertising: Sophisticated print, online, e-mail and social media marketing.

Advocacy: Influence on local and regional legislation and policies that affect the business community.Find out more at berkeleychamber.com.

berkeley lab commercial

venturesFigures for 2014:

$4.07 MRoyalties received

$1.27 MRoyalties distributed

128Researchers receiving

royalties

170New inventions/software

173U.S. and foreign patent

applications

$52.23 MFunds from non-federal work

agreements

UC berkeley at a glance

#1Public university*

#2In universities producing venture capital-backed

entrepreneurs

#3Global university*

#2In social entrepreneurship

Continued on next page

Continued from previous page

* 2016 academic ranking of World universities


Four Twenty Seven:Adapting to climate change


W ith the rare exception, most people no longer deny the reality of climate change, instead they’re learning to adapt.

“The frequency and severity of extreme weather events is already increasing as global tempera-tures rise. Businesses, governments and communities are already beginning to experience the im-

pact of the changing environment,” says Jay Koh, managing director and partner at Siguler Guff & Company.“Experts like Four Twenty Seven, a climate resilience and advisory firm, provide communities, governments and

businesses with an important and practical approach to understanding and addressing the effects of a changing climate,” notes Koh, whose New York venture capital firm works closely with the Berkeley-based company.

Four Twenty Seven – named for California’s 2020 greenhouse gas emissions target – was founded in 2012 to help clients translate complex scientific data into actionable strategies.

“Telling business that it will be 2 degrees warmer is useless,” says Emilie Mazzacurati, Four Twenty Seven’s founder and CEO. “They need to understand how changes in temperature will concretely affect their operations

and the value chain.” Previously, Mazzacurati was working on policy issues designed to prevent climate

change from happening, but when Congress failed to act she switched to adaptation and resiliency issues.

“We’re a climate risk analytics and market-intelligence firm,” says Mazzacurati. “We provide customized solutions that blend economic modeling with climate science to help clients quantify the risks of climate change and monetize costs.”

Risk management is a billion dollar industry in the U.S. With extreme weather events estimated to cost the U.S. economy upwards of $100 billion a year, the need for Four Twenty Seven’s services are clear – and the growth potential enormous.

Providing guidance around climate risk dis-closures is a critical step to help multinational

corporations and investors avoid being blindsided by predictable risks. What sets Four Twenty Seven apart is their focus on quantifying economic

impacts from climate change at a very fine scale.“We help businesses and public agencies understand how the changes are

going to affect what they track on a daily basis, whether it’s revenue or public health indicators,” says Mazzacurati.

For global corporations, like 3M, Four Twenty Seven has mapped the risks due to climate change on the network of industries, countries and commodities that make up the global supply chain.

“As a science-based company with diverse global operations, we appreciate their expertise in interpreting the complex re-sults of their analysis, which provides tangible value, and helps companies identify real projects to tackle the impacts of climate change on their supply chain,” says Dawn Krue-ger, sustainability supply chain manager at 3M.

Mazzacurati, who is from France, attended UC Berkeley’s Goldman School of Public Policy and chose to start her company in Berkeley because of Califor-nia’s “leadership in everything climate change.”

“We’re surrounded by local and state govern-ments that are leaders on climate issues, and we’re able to draw on the incredible intellectual resources at UC Berkeley,” says Mazzacurati. “This is where the foremost thinkers on climate issues are.”

Four Twenty Seven is currently working on a suite of products to account for how climate change can impact financial markets.

“Climate change is a major social and economic issue that businesses can no longer ignore,” says Mazzacurati.

“Telling business that it will be 2 degrees warmer is useless. They need to

understand how changes in temperature will concretely affect their operations and

the value chain.”

Emilie Mazzacurati, Founder and CEO, Four Twenty Seven

B erkeley businesses get it – they have a strong stake in helping to improve STEM (science, technology, engineering and math) education. Investing in STEM is an investment in the skill

sets their future employees will need to succeed in the new economy.

A growing public-private collaboration aimed at building a local STEM talent pipeline is designed to en-courage students to pursue STEM-related careers and inspire them to see these careers as within their grasp.

Making Science Make SenseFor Bayer, one of the largest biotech employers in

the Bay Area, getting children interested in science has been a long-term goal. Its national award-winning Making Science Make Sense program is a company-wide initiative to advance science literacy. Bayer employees take time out to visit schools and help teachers teach and students learn science the way scientists do – by doing it.

berkeley biotech PartnersSince 1993, Biotech Partners has focused on training students for

technical and higher positions in bioscience, and currently trains stu-dents at Berkeley High School and Oakland Technical High School.

The program, established by Bayer and the City of Berkeley in 1992, includes academics, personal support services and paid internships.

“It’s been such a success that Biotech Partners is now ‘scaling up’ by broadening the program to include other Bay Area companies and more schools,” says Joerg Heidrich, head of the Bayer Berkeley site. Biotech Partners is expanding to new school districts with the support of its more than 35 corporate, government, education and industry partners.

Corporate partners provide not only financial support, but serve as an advisory council. Key stakeholders – teachers, industry representa-tives and staff – ensure the training is aligned with trends in biotechnol-ogy and regional workforce development.

Biotech Partners is nationally recognized as a model for urban youth education and workforce development that includes paid internships, development of innovative curriculum and teacher training.

More than 200 students have completed their studies in the Biotech Partners program and more than 100 have secured jobs in biotech. Bayer

has provided internships to 525 Biotech Partners students and hired more than 60 graduates since the inception of the program.

In addition, Bayer partners with the Community Resources for Science program to provide teachers with training and resources to enhance hands-on science lesson.

STeM Institute at Cal State east bayBayer brought Wareham Development in to help

start the STEM Institute at Cal State East Bay to im-prove the teaching of STEM skills, while encourag-ing students to pursue careers in related fields. A key aspect of the program is to increase diversity both

in STEM education and in industry. It’s a “long-term investment,” says Heidrich. “By getting young people engaged in science and technology early on, they will hopefully want to continue along those lines.”

Rich Robbins, president of Wareham Development, agrees: “We have serious work to do that cannot wait. Wareham is committed to STEM education as one way to mitigate the enormous challenges fac-ing the Bay Area and our country – not only for the sake of our young people but for the future of the oldest and largest innovation cluster in the world.”

STeM Career Awareness DayIn April, Bayer and Wareham partnered with the STEM Institute to

host the fourth annual Career Awareness Day. More than 300 local high school students toured 25 participating STEM companies within walking distance of Wareham’s West Berkeley campus. Students enjoyed lunches with STEM professionals from another 30 science, tech and manufac-turing companies plus hands-on demonstrations to learn about the jobs awaiting them. Other key participants included the City of Berkeley, Dy-navax, Aduro Biotech, the Port of Oakland and the East Bay Economic Development Alliance.

“STEM Career Awareness Day is one component of a comprehen-sive approach that includes increasing the number of businesses engaged in direct work with students and educators, training a diverse teacher corps, and bringing hands-on science learning labs into challenged com-munities,” adds Robbins.

Berkeley business invests in STEM”Kids love science,

because it’s discovering

the world around you.”

Dr. Mae C. JemisonFirst African-American woman in space and chief ambassador for Bayer’s Making Science Make

Sense initiative

Bayer’s Making Science Make Sense program is taught by Bayer employees who visit schools to help students learn through hands-on science experience.

Introduced by Michael McCormick AICP, senior planner, California Governor’s Office of Planning and Research; focus on the nexus of high-level climate change goals and

local implementation.

bayer

paolo vescia


Company, the BFF has awarded more than $1,000,000 to local filmmakers, including 30 student filmmakers. While in production and beyond, all the BFF-granted films are feeding the local work-force while employing other Bay Area industry professionals.

Abby Ginzberg, an award-win-ning documentary filmmaker and president of the BFF board sug-gests a natural link between art, science and the creative communi-ties in Berkeley and along the East Shore.

“The art of documentary film-making is actually very similar to scientific endeavor,” says Ginzberg. “Both entail research with open–mindedness to find the truth in the story or the proof in the research. Both endeavors elicit more questions as part of the journey.”

“The BFF has funded several documentaries that clearly show the creativity in science,” she adds, citing, for example: “My Love Affair with the Brain: The Life and Science of Dr. Marian Di-amond,” by Catherine Ryan and Gary Weimberg,

which follows the remarkable UCB professor, Marian Diamond.

“In ‘Inequality for All,’ by Jacob Kornbluth, for-mer Secretary of Labor Robert Reich shares the research of his UCB students and reveals the con-fluence of political science and economics in a way that has changed the discussion forever,” she adds.

Thank you, sponsors.These Berkeley businesses and institutions supported the 2016 Berkeley Visionary Awards.

PLATINUM SPONSORS

SUPPORTING SPONSORS

Past honorees of the Berkeley Visionary Awards

W hile often seen as polar oppo-sites, one driven by left-brain logic and quantitative analy-sis, the other emanating from

right-brain qualitative expressiveness, the similarities between how scientists and artists think and work are striking.

It’s a lesson learned at a young age by Susan Medak, Berkeley Repertory Theatre manag-ing director, whose scientist father would talk about his research being driven by his imagi-nation.

Medak had the connection between the arts and science reinforced on a visit to Flo-rence some years ago. After spending a morn-ing at the Uffizi, studying the magnificent art collection created by the Medicis, Medak dropped in on a museum dedicated to scien-tific discoveries that was also funded by the Medici family.

“They understood that the creative im-pulse that leads to scientific breakthroughs is the same impulse that leads great artists to make great art. It all starts with an idea.”

Taking an open-minded approach to prob-lems is also a characteristic of innovative en-trepreneurs who have the vision and drive to make something new.

This year’s celebration of the Berkeley Vi-sionary Awards takes place at the new Peet’s Theatre at Berkeley Rep, a setting emblematic of the nexus between the arts, science and tech-nology and forward-thinking entrepreneurship.

“Berkeley Rep, Peet’s and Meyer Sound all started around the same time – we’re all part of the Berkeley ethos,” says Medak. “We each imagined something new and created an au-dience for something that hadn’t been there before.”

“Alfred Peet invented coffee – artisanal and beautifully crafted – as we know it now. Meyer’s Constellation sound system, which is installed in the new theater, makes it possible to change the resonance of a room without changing the physical architecture. In our case, we created an audience for more adven-turesome, provocative work than was gener-ally available up until then.”

Rhonda Shrader, director of the UC Berke-ley-Haas Entrepreneurship Program, agrees that the meetup of arts and science is essential to what makes Berkeley such a rich environ-ment for entrepreneurship.

“I’m a huge theater and dance fan,” says Shrader. “That’s where I find inspiration, not from reading business publications. Art is the ultimate entrepreneurship. The artist is taking

nothing and making it into something.” “The willingness to share and exchange

ideas is what gives Berkeley the edge over other places,” says Shrader. “The mix makes it better for all of us – academics, scientists, art-ists and adventurous entrepreneurs.”

Saul Zaentz Center & berkeley FIlM Foundation

Berkeley’s arts scene includes the Saul Zaentz Center (SZC), a celebrated building originally designed to house Fantasy Records and the accompanying Fantasy Studios, as well as Saul Zaentz Films, creators of Oscar-win-ning films “One Flew Over the Cuckoo’s Nest,” “Amadeus” and “The English Patient.”

In 2007, Wareham Development purchased and restored the Saul Zaentz Center, which is still home to the Saul Zaentz Company,

Fantasy Studios and many of the Bay Area’s award-winning independent filmmakers; as well as home to Avid Technologies, WLC Ar-chitects, Eko Devices and others.

This fall, Fantasy Studios re-opened the building’s legendary mix theater used for post- production of over 200 films. The Fan-tasy Film Center is designed for the film, tele-vision and video game industries and features new equipment from Berkeley innovators Avid Technologies and Meyer Sound.

An innovative public-private partnership to benefit the arts, the Berkeley FILM Foun-dation (BFF), is one of the major funders of film in the Bay Area and, perhaps, the only public-private collaboration of its kind in the country.

Founded in 2009 by the City of Berkeley, Wareham Development and the Saul Zaentz

“The Bay Area is a magnet for mavericks impatient to reinvent

the world.”

Ken Goldberg, UC Berkeley professor of engineering and artist

art and science inspire Berkeley’s entrepreneurs

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Above: Peet’s Theatre at Berkeley Rep. Below: A scene from ‘My Love Affair with the Brain: The Life and Science of Dr. Marian Diamond,’ a Berkeley Film Foundation- funded documentary about UCB professor Marian Diamond.

“Berkeley Rep, Peet’s and Meyer Sound – we’re all part of the Berkeley ethos. We each imagined something new and created an audience for something that hadn’t been there before.”

Susan Medak, Berkeley Repertory Theatre managing director

The interior of the new Berkeley Art Museum/Pacific Film Archive.

2015Jill Fuss, Founder & cto/coo CinderBio

Will Wright, legendary game designer& co-founder stupid Fun Club and thred; creator of simcity

vivienne ming, Founder & executive chairsocos Learning

2014 sylvain costes, ph.d., co-founderexogen Biotechnology

chris Anderson, co-founder3D Robotics

2013patrick KennedyownerPanoramic interests

steven viscoceo and ctoPolyPlus Battery Co.


Other Machine Co.:Tools for the maker’s desktop


Danielle Applestone, CEO, Other Machine Co.

I t should come as no surprise that Danielle Applestone, CEO of Other Machine Co. (OMC), would grow up to found a business that designs and makes desktop manufacturing machines.

A self-described country girl, Applestone was expected to help out with chores and no one ever told her she shouldn’t handle a drill because she was a girl.

“I did what was needed. There were never questions about limitations,” says Applestone. “I wish more people had that experience.”

It’s the same “do what needs doing” attitude that was the impetus for Applestone founding OMC.“The company was founded out of necessity,” says Applestone. “We started as a government sponsored project to de-

velop low-cost computer numerical control (CNC) machines for schools. And then the funding dried up.”Applestone didn’t waver. With the hardware and software she and her engineering team had designed, she launched

Other Machine Co. “We’re dedicated to giving the next generation of designers and makers access to manufacturing tools,” says Applestone. OMC’s Othermill is a desktop cutter that can etch circuit boards and carve complex 3D shapes in metal, wood and

other materials. Like 3D desktop printer firms, OMC is converting an industrial technology into a tool everyone can use.

Unlike a 3D printer, which extrudes materials from a cartridge, the Othermill removes material from a block of material or circuit board to create a functional object based on a digital design.

The latest model Othermill Pro is quiet, affordable at around $3,000 and small enough to sit on a kitchen table, making it accessible to home studios and businesses – and the software makes it easy to use with minimal training.

“If we’re going to revitalize manufacturing in this country, we need to close the gap and give people access to professional tools,” says Applestone, who has a degree from MIT and a PhD from the University of Texas at Austin.

The Othermill and Othermill Pro cut out the middleman and speed up the product design process, explains Applestone.

“Prior to this, people would need years of training to use the big, complicated machines that were available – if they had access at all,” says Ap-plestone. “Even mechanical engineers had to turn their designs over to someone else to make. In today’s market, that takes too long. People are used to new products coming out at such a fast pace.”

The Othermill can be used to make prototypes and manufacture small products, from circuit boards to machine parts and jewelry.

“We’re putting tools into the hands of entrepreneurs who are creating a whole new generation of businesses, as well as enabling Fortune 100 companies who want to innovate faster,” says Applestone.

OMC is also finding new customers among schools and univer-sities.

UC Berkeley’s CITRIS Invention Lab is a good example. CIT-RIS was founded some 15 years ago when UC researchers realized real opportunities lay not just in developing new innovative tech-nologies, but in applying them.

“The machine and control software are very easy to learn, so we can train many more students to operate the machine inde-pendently themselves,” says Bjoern Hartmann, assistant profes-sor in the program.

Applestone, who started OMC in San Francisco, moved to Berkeley for the lifestyle, the broad spectrum of talent and proximity to the East Bay’s growing advanced manufactur-ing sector.

“It was impossible to find space in San Francisco,” says Applestone. “By moving to West Berkeley we more than doubled our square footage – and we have a loading dock.”

“In San Francisco, you can do only one thing: soft-ware. Here you can do everything!”

“We’re dedicated to giving the next generation of

designers and makers access to

manufacturing tools.”

Introduced by Saul GriffithInventor and MacArthur fellow; founder or co-founder of seven companies, including Otherlab, Makani Power and

Instructables

paolo vescia


[email protected] | 415-701-7000

CITYSPACES® MicroPAD™

9th & Mission, SF

Innovation in Housing the Homeless:

Come and take a tourOctober 21 - November 4

1 pm - 5 pm

“We believe our focus on creating strategic growth plans over business plans gives our participants a com-petitive edge in the marketplace.” IEL Director and business strategist, Dina Finta, on the secret to IEL participants’ success.

These innovative programs have recently evolved to be even more accessible with a hybrid format of in-person, virtual lectures and individual mentorship.

Advanced Certificate in Entrepreneurship (ACE)A five-month certificate with 13 hours of one-on-one mento-ring time making it a truly customizable experience for where you are in your business cycle. Enroll now for November 2nd. Business Growth Acceleration Program (BGAP) A six-month intensive addressing supplier diversity and the needs of minority business enterprises. New group starts January 19th, 2017.

In its �rst �ve years, the Institute of Entrepreneurial Leadership (IEL) has helped over 220 Visionary Leaders start and grow their companies, collectively generating more than $1.70 billion in revenues with 9% average growth rates and employing 4,048 people.

Visit jfku.edu/iel

Helping businesses start up and grow

B erkeley’s Office of Economic Development and a net-work of collaborating organizations are as entrepre-neurial and innovative as the businesses they stand ready to assist. They thrive on helping businesses at ev-

ery stage – new, old, well established or still just a brilliant idea – get started and grow.

berkeley’s Office of economicDevelopmentcityofberkeley.info/oedAssistance with commercial real estate, financing, economic data, green business, marketing – and making connections with peers and mentors.2180 Milvia St.Berkeley, CA [email protected]

berkeley Startup Clusterberkeleystartupcluster.comProvides resources for high-growth, tech-related companies.

locate in berkeleylocateinberkeley.infoListings to help business owners find the right space at the right price – from corporate headquarters to retail, restaurants, lab facilities and manufacturing.

Tech Futures Grouptechfuturesgroup.orgProvides no-cost advising in IP, fundraising, and financial planning for qualifying technology businesses.

berkeley loan fundcityofberkeley.info/loanfund Access to capital for qualifying businesses.

UC berkeley InnovatorsInnovators.berkeley.eduOffers a portal into innovation resources across the UC Berkeley campus serving entrepreneurs, investors and industry.

UC berkeley Vice Chancellor for researchvcresearch.berkeley.edu/innovation/programsProvides extensive listings of programs from industry partnerships to entrepreneurial support to alumni engagement.

lawrence berkeley lab’s Innovation & Partnerships Officeipo.lbl.govMoves technologies from the lab to the marketplace through partnerships in the private and public sectors.

Cyclotron roadcyclotronroad.comTrains qualifying energy innovators to drive commercial impact.

Founder Martin Zemitis of SlingFin Inc. poses with the company’s Alpine Zone Kahiltna Dome Tents, designed to withstand condi-tions at the Mt. Everest base camp. SlingFin has been a participant in the City of Berkeley’s Revolving Loan Fund portfolio since 2015.

EVERYONE’S A LITTLE BERKELEY

In our city overlooking the San Francisco Bay, we’re backyard artists and world-class creators. We’re the capital of culinary and the hub of homegrown. We’re a city of people who are never done asking, and we’re inventors whose whole world is our lab. We invite you to enjoy our locally-sourced inspiration in all its forms: our scenic parks, our famous stages, our distinguished university, our renowned restaurants. Come mix flavors, change tempos, and break molds. Go ahead, be bold. Be a little Berkeley.

Visitor Information Center, 2030 Addison Street, #102(800) 847-4823visitberkeley.com

16 Advertising supplement berkeley | visionary awards 2016 sAn FrAncisco Business TiMes

West Berkeley mavericks all.

Aduro BiotechAnven BiosciencesAlturas FilmsAmir SolantiAvid TechnologiesBAE Urban EconomicsBay Area Film CompanyBayer HealthcareBerkeley FILM FoundationBerkeley East Bay Humane SocietyBerkeley Sound ArtistsBerkeley Media, LLCBeyond the ArcBriaCell TherapeuticsBuddhist Film SocietyCaribou BiosciencesCA Dept. of Toxic Substances ControlCMC BiologicsCinder BiologicsClarity FilmsColumbus ITCPI InternationalCyperus MediaDynavaxDysonics, Inc.Eko DevicesEyefull Tower FilmsFantasy Film CenterFantasy StudiosFarallon FilmsFrame of Mind Films

HJ Science & TechnologyInternational Buddhist Film FestivalInterfaze Educational ProductionsIP FolioJason Cohen ProductionsJed Riffe FilmsK. Ford & AssociatesKovno CommunicationsKUKU StudiosThe Law Office of David A. LermanLaw Office of John McArthurLawrence Berkeley National LaboratoryLigandal, Inc.Light Sail EnergyMichael Romanowski MasteringMint LeafMoly Lab, Inc.Montell AssociatesNanotech BiomachinesNew Images ProductionsNorthstarr Media GroupNuRealityODMROne to One BoxOriel TherapeuticsParadigm ProductionsPictureStartEditPivotPixar Child Development CenterPro PublicaQB3 East Bay Innovation Center

Quest ProductionsQuestion Why FilmsR3 Consulting GroupReel Youth ProductionsRegimmuneRiva CucinaRL & AssociatesRodan & FieldsSandra Horwich & Assoc.Saratoga Energy ResearchSiemens Healthcare Molecular TherapeuticsSilicon BiodevicesSnitow Kaufman ProductionsSocial Action Media Small Change ProductionsSmilablesStephen Kong ConsultingSwan EntertainmentTexas Saratoga ManagementTavistock Restaurant Group Thin-Thick ProductionsWLC ArchitectsUrban AdamahValitor, Inc.Wells Fargo BankXomaYoung People’s Symphony OrchestraZamacona ProductionZD FilmsThe Saul Zaentz CompanyZamacona Productions

Emeryville · Berkeley · Richmond · Marin County · Palo Alto · Sun Valley, ID · 415 457 4964 · www.warehamdevelopment.com

Distinguished buildings for noble and Nobel innovators since 1977.

From international corporations to small startups, tenants at our Aquatic Park Center and Saul Zaentz Center campuses in West Berkeley are among the most creative innovators in research, tech, documentary and independent film, and music. We are proud of all they bring to Berkeley and to the world.

berkeley special adverti sing supplement visionary ......building. “it takes intelligence,...

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