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Biochemical Systematics and Ecology 31 (2003) 635636www.elsevier.com/locate/biochemsyseco

A rare avonol glycoside from Polygalachinensis

Menini S. Rao a,a# , P.S. Rao b , J.K. Kumar b , N.V. Raman c ,Md. Khalilullah c

a Department of Chemistry, Oakland University, Rochester, Michigan 48309, USAb Department of Chemistry, Kakatiya University, Warangal, A.P. India

c Department of Chemistry, J.N.T. UniversityKukatpally, Hyderabad, India

Received 20 September 2000; accepted 9 September 2002

Keywords: Polygala chinensis ; Polygalaceae; Whole plant; Eupalitin-3- O-- D galactoside; Flavonolglycoside

1. Subject and Source

Polygala chinensis Geissman (Polygalaceae), a herb with glabrescent leaves andyellow owers found in open places and grasslands.

The whole plant of P. chinensis was collected from Nagarjuna University Campus,Guntur, Andhra Pradesh in September 1999. the plant was identied by Prof. P.N.Rao, Department of Botany, Nagarjuna University, Guntur. A Voucher specimen of

the plant material (Np. PC-101) is preserved in the herbarium of Department of Botany, Sri Krishnadevaraya University, Anantapur, Andhrapradesh, India (SKU).

2. Previous Work

Six new lactonic lignans and avonol glycosides (Ghosal et al., 1974)

a# Corresponding author: Meneni.S.Rao, Dept. of Chemistry, Oakland University, 31950 Concord Dr.,Madison Heights, MI-48071, USA.

E-mail address: raoFms@yahoo.com (M.S. Rao).

0305-1978/02/$ - see front matter 2002 Elsevier Science Ltd. All rights reserved.doi:10.1016/S0305-1978(02)00201-6

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3. Present Study

The dried whole plant of P. chinensis was extracted with methanol (MeOH) for5-6 hrs. The concentrated extract was puri ed by column chromatography over silicagel to afford eupalitin-3-O- -D-galactoside (1). The physical (m.p., [ ]D ) and spec-tral (IR, 1 H and 13 C NMR and MS) properties of the compound were found to beidentical to those reported earlier (Smith et al., 1971). This is the rst report of theisolation of the compound from P. chinensis .

4. Chemotaxonomic Signicance

Eupalitin-3-O- -D galactoside and related avonol glycosides have previouslybeen isolated from other Polygala species (Dubois et al., 1985; Hamburger et al.,1986; Do et al., 1992; Jung et al., 1993; Wenkui et al., 1996). These avonol glycos-ides may be useful taxonomic markers within the genus.

Acknowledgements

The authors thank Prof. H. Duddeck, Institute of Organic Chemistry, HannoverUniversity, Hannover, Germany for providing Spectral data. N.V. and M.K. are

thankful to Dr. Ram Reddy, Principal and M.S.N. Raju, Head, Department of Chem-istry, J.N.T. University, Kukatpally, Hyderabad.

References

Do J.C., et al., 1992, Saemgual Jaljpejo, 23(1), 9.Dubois M.A., et al., 1985, Phytochemistry, 28(2), 3355.Ghosal, S., et al., 1974, Phytochemistry, 12 ,2281.Hamburger, M., Hostettmann, K., 1986, Journal of Natural Products, 49(3), 557.Jung, Keuh Young et al., 1993, Phytochemistry, 34(4), 1196.

Smith, D.M., et al., 1971, Phytochemistry, 10, 3115.Wenkui et al., 1996. Tiauran Chanwu Yanjiu Yu Kaifu, 8(3), 1.