bioinformatic tools in pheromone technology

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ROLE OF BIOINFORMATICS TOOLS IN PHEROMONE TECHNOLOGY LS 1154, M.THILAKAR, 4’th M.Sc. LIFE SCIENCES, BHARATHIDASAN UNIVERSITY, TIRUCHIRAPALLI..

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Page 1: Bioinformatic tools in Pheromone technology

ROLE OF BIOINFORMATICS TOOLS

IN PHEROMONE TECHNOLOGY

LS 1154

MTHILAKAR

4rsquoth MSc LIFE SCIENCES

BHARATHIDASAN UNIVERSITY

TIRUCHIRAPALLI

BIOINFORMATICS - INTRODUCTIONBIOLOGY + INFORMATICS = BIOINFORMATICS

Deals with Data of Biology with the aid of computers and theirprograms

The programs are specially designed for the purpose of Biologicaldata analysis

Biomolecules like Protein Nucleic acids are predominantly subjectedto analyses

462015 2LS1154 - MTHILAKAR

BIOINFORMATICS TOOLS

Tools in the sense of Software packages

Software packages are written as coding and are prepared asexecutable files

Already existing software are available through online

Programs like C C++ PERL Python etc are commonly used tocreate these software packages

462015 3LS1154 - MTHILAKAR

ABOUT UNIPROT

The mission of UniProt is to provide the scientific community with acomprehensive high quality and freely accessible resource of protein sequenceand functional information

UniProt is comprised of four components each optimized for different uses

1) The UniProt Knowledgebase (UniProtKB) is the central access point forextensive curated protein information including function classification andcross-reference

It consists of two sections

UniProtKBSwiss-Prot which is manually annotated and is reviewed and

UniProtKBTrEMBL which is automatically annotated and is not reviewed

2) The UniProt Reference Clusters (UniRef) databases provide clustered setsof sequences from the UniProtKB and selected UniProt Archive records toobtain complete coverage of sequence space at several resolutions while hidingredundant sequences

3) The UniProt Archive (UniParc) is a comprehensive repository used to keeptrack of sequences and their identifiers

4) The UniProt Metagenomic and Environmental Sequences (UniMES) databaseis a repository specifically developed for metagenomic and environmental data

462015 4LS1154 - MTHILAKAR

WHY IS UNIPROTKB COMPOSED OF 2 SECTIONSUNIPROTKBSWISS-

PROT AND UNIPROTKBTREMBL

UniProtKBSwiss-Prot

Created in 1986

Manually annotated andnon-redundant proteinsequence database

Brings together theexperimental resultscomputed features andscientific conclusions

UniProtKBTrEMBL

Created in 1996

Because of the increased dataflowwhich is resulting from HumanGenome project

Contains high quality computationallyanalyzed data and are automaticannotation with classification

Unreviewed entries kept separatedform Swiss-Prot

462015 5LS1154 - MTHILAKAR

UNIPROT ndash HOME PAGE httpwwwuniprotorg

462015 6LS1154 - MTHILAKAR

SEARCHING ON UNIPROT (ADVANCED)

462015 7LS1154 - MTHILAKAR

RESULT PAGE -COMPLETE

462015 8LS1154 - MTHILAKAR

RESULT PAGE ndash SELECTED ORGANISM MOUSE

462015 9LS1154 - MTHILAKAR

RESULTS ARE DOWNLOADABLE

462015 10LS1154 - MTHILAKAR

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

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UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

DD

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EN

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MIS

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N

KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 2: Bioinformatic tools in Pheromone technology

BIOINFORMATICS - INTRODUCTIONBIOLOGY + INFORMATICS = BIOINFORMATICS

Deals with Data of Biology with the aid of computers and theirprograms

The programs are specially designed for the purpose of Biologicaldata analysis

Biomolecules like Protein Nucleic acids are predominantly subjectedto analyses

462015 2LS1154 - MTHILAKAR

BIOINFORMATICS TOOLS

Tools in the sense of Software packages

Software packages are written as coding and are prepared asexecutable files

Already existing software are available through online

Programs like C C++ PERL Python etc are commonly used tocreate these software packages

462015 3LS1154 - MTHILAKAR

ABOUT UNIPROT

The mission of UniProt is to provide the scientific community with acomprehensive high quality and freely accessible resource of protein sequenceand functional information

UniProt is comprised of four components each optimized for different uses

1) The UniProt Knowledgebase (UniProtKB) is the central access point forextensive curated protein information including function classification andcross-reference

It consists of two sections

UniProtKBSwiss-Prot which is manually annotated and is reviewed and

UniProtKBTrEMBL which is automatically annotated and is not reviewed

2) The UniProt Reference Clusters (UniRef) databases provide clustered setsof sequences from the UniProtKB and selected UniProt Archive records toobtain complete coverage of sequence space at several resolutions while hidingredundant sequences

3) The UniProt Archive (UniParc) is a comprehensive repository used to keeptrack of sequences and their identifiers

4) The UniProt Metagenomic and Environmental Sequences (UniMES) databaseis a repository specifically developed for metagenomic and environmental data

462015 4LS1154 - MTHILAKAR

WHY IS UNIPROTKB COMPOSED OF 2 SECTIONSUNIPROTKBSWISS-

PROT AND UNIPROTKBTREMBL

UniProtKBSwiss-Prot

Created in 1986

Manually annotated andnon-redundant proteinsequence database

Brings together theexperimental resultscomputed features andscientific conclusions

UniProtKBTrEMBL

Created in 1996

Because of the increased dataflowwhich is resulting from HumanGenome project

Contains high quality computationallyanalyzed data and are automaticannotation with classification

Unreviewed entries kept separatedform Swiss-Prot

462015 5LS1154 - MTHILAKAR

UNIPROT ndash HOME PAGE httpwwwuniprotorg

462015 6LS1154 - MTHILAKAR

SEARCHING ON UNIPROT (ADVANCED)

462015 7LS1154 - MTHILAKAR

RESULT PAGE -COMPLETE

462015 8LS1154 - MTHILAKAR

RESULT PAGE ndash SELECTED ORGANISM MOUSE

462015 9LS1154 - MTHILAKAR

RESULTS ARE DOWNLOADABLE

462015 10LS1154 - MTHILAKAR

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

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462015 LS1154 - MTHILAKAR 35

DD

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462015 LS1154 - MTHILAKAR 36

DD

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SE

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EN

CE

S

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MIS

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 3: Bioinformatic tools in Pheromone technology

BIOINFORMATICS TOOLS

Tools in the sense of Software packages

Software packages are written as coding and are prepared asexecutable files

Already existing software are available through online

Programs like C C++ PERL Python etc are commonly used tocreate these software packages

462015 3LS1154 - MTHILAKAR

ABOUT UNIPROT

The mission of UniProt is to provide the scientific community with acomprehensive high quality and freely accessible resource of protein sequenceand functional information

UniProt is comprised of four components each optimized for different uses

1) The UniProt Knowledgebase (UniProtKB) is the central access point forextensive curated protein information including function classification andcross-reference

It consists of two sections

UniProtKBSwiss-Prot which is manually annotated and is reviewed and

UniProtKBTrEMBL which is automatically annotated and is not reviewed

2) The UniProt Reference Clusters (UniRef) databases provide clustered setsof sequences from the UniProtKB and selected UniProt Archive records toobtain complete coverage of sequence space at several resolutions while hidingredundant sequences

3) The UniProt Archive (UniParc) is a comprehensive repository used to keeptrack of sequences and their identifiers

4) The UniProt Metagenomic and Environmental Sequences (UniMES) databaseis a repository specifically developed for metagenomic and environmental data

462015 4LS1154 - MTHILAKAR

WHY IS UNIPROTKB COMPOSED OF 2 SECTIONSUNIPROTKBSWISS-

PROT AND UNIPROTKBTREMBL

UniProtKBSwiss-Prot

Created in 1986

Manually annotated andnon-redundant proteinsequence database

Brings together theexperimental resultscomputed features andscientific conclusions

UniProtKBTrEMBL

Created in 1996

Because of the increased dataflowwhich is resulting from HumanGenome project

Contains high quality computationallyanalyzed data and are automaticannotation with classification

Unreviewed entries kept separatedform Swiss-Prot

462015 5LS1154 - MTHILAKAR

UNIPROT ndash HOME PAGE httpwwwuniprotorg

462015 6LS1154 - MTHILAKAR

SEARCHING ON UNIPROT (ADVANCED)

462015 7LS1154 - MTHILAKAR

RESULT PAGE -COMPLETE

462015 8LS1154 - MTHILAKAR

RESULT PAGE ndash SELECTED ORGANISM MOUSE

462015 9LS1154 - MTHILAKAR

RESULTS ARE DOWNLOADABLE

462015 10LS1154 - MTHILAKAR

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

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EN

CE

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UB

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SIO

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462015 LS1154 - MTHILAKAR 35

DD

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SE

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SIO

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462015 LS1154 - MTHILAKAR 36

DD

BJ

SE

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EN

CE

S

UB

MIS

SIO

N

KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 4: Bioinformatic tools in Pheromone technology

ABOUT UNIPROT

The mission of UniProt is to provide the scientific community with acomprehensive high quality and freely accessible resource of protein sequenceand functional information

UniProt is comprised of four components each optimized for different uses

1) The UniProt Knowledgebase (UniProtKB) is the central access point forextensive curated protein information including function classification andcross-reference

It consists of two sections

UniProtKBSwiss-Prot which is manually annotated and is reviewed and

UniProtKBTrEMBL which is automatically annotated and is not reviewed

2) The UniProt Reference Clusters (UniRef) databases provide clustered setsof sequences from the UniProtKB and selected UniProt Archive records toobtain complete coverage of sequence space at several resolutions while hidingredundant sequences

3) The UniProt Archive (UniParc) is a comprehensive repository used to keeptrack of sequences and their identifiers

4) The UniProt Metagenomic and Environmental Sequences (UniMES) databaseis a repository specifically developed for metagenomic and environmental data

462015 4LS1154 - MTHILAKAR

WHY IS UNIPROTKB COMPOSED OF 2 SECTIONSUNIPROTKBSWISS-

PROT AND UNIPROTKBTREMBL

UniProtKBSwiss-Prot

Created in 1986

Manually annotated andnon-redundant proteinsequence database

Brings together theexperimental resultscomputed features andscientific conclusions

UniProtKBTrEMBL

Created in 1996

Because of the increased dataflowwhich is resulting from HumanGenome project

Contains high quality computationallyanalyzed data and are automaticannotation with classification

Unreviewed entries kept separatedform Swiss-Prot

462015 5LS1154 - MTHILAKAR

UNIPROT ndash HOME PAGE httpwwwuniprotorg

462015 6LS1154 - MTHILAKAR

SEARCHING ON UNIPROT (ADVANCED)

462015 7LS1154 - MTHILAKAR

RESULT PAGE -COMPLETE

462015 8LS1154 - MTHILAKAR

RESULT PAGE ndash SELECTED ORGANISM MOUSE

462015 9LS1154 - MTHILAKAR

RESULTS ARE DOWNLOADABLE

462015 10LS1154 - MTHILAKAR

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

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462015 LS1154 - MTHILAKAR 34

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 5: Bioinformatic tools in Pheromone technology

WHY IS UNIPROTKB COMPOSED OF 2 SECTIONSUNIPROTKBSWISS-

PROT AND UNIPROTKBTREMBL

UniProtKBSwiss-Prot

Created in 1986

Manually annotated andnon-redundant proteinsequence database

Brings together theexperimental resultscomputed features andscientific conclusions

UniProtKBTrEMBL

Created in 1996

Because of the increased dataflowwhich is resulting from HumanGenome project

Contains high quality computationallyanalyzed data and are automaticannotation with classification

Unreviewed entries kept separatedform Swiss-Prot

462015 5LS1154 - MTHILAKAR

UNIPROT ndash HOME PAGE httpwwwuniprotorg

462015 6LS1154 - MTHILAKAR

SEARCHING ON UNIPROT (ADVANCED)

462015 7LS1154 - MTHILAKAR

RESULT PAGE -COMPLETE

462015 8LS1154 - MTHILAKAR

RESULT PAGE ndash SELECTED ORGANISM MOUSE

462015 9LS1154 - MTHILAKAR

RESULTS ARE DOWNLOADABLE

462015 10LS1154 - MTHILAKAR

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

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CE

S

UB

MIS

SIO

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462015 LS1154 - MTHILAKAR 34

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 6: Bioinformatic tools in Pheromone technology

UNIPROT ndash HOME PAGE httpwwwuniprotorg

462015 6LS1154 - MTHILAKAR

SEARCHING ON UNIPROT (ADVANCED)

462015 7LS1154 - MTHILAKAR

RESULT PAGE -COMPLETE

462015 8LS1154 - MTHILAKAR

RESULT PAGE ndash SELECTED ORGANISM MOUSE

462015 9LS1154 - MTHILAKAR

RESULTS ARE DOWNLOADABLE

462015 10LS1154 - MTHILAKAR

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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S

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 7: Bioinformatic tools in Pheromone technology

SEARCHING ON UNIPROT (ADVANCED)

462015 7LS1154 - MTHILAKAR

RESULT PAGE -COMPLETE

462015 8LS1154 - MTHILAKAR

RESULT PAGE ndash SELECTED ORGANISM MOUSE

462015 9LS1154 - MTHILAKAR

RESULTS ARE DOWNLOADABLE

462015 10LS1154 - MTHILAKAR

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

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SE

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462015 LS1154 - MTHILAKAR 35

DD

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462015 LS1154 - MTHILAKAR 36

DD

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CE

S

UB

MIS

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 8: Bioinformatic tools in Pheromone technology

RESULT PAGE -COMPLETE

462015 8LS1154 - MTHILAKAR

RESULT PAGE ndash SELECTED ORGANISM MOUSE

462015 9LS1154 - MTHILAKAR

RESULTS ARE DOWNLOADABLE

462015 10LS1154 - MTHILAKAR

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 35

DD

BJ

SE

QU

EN

CE

S

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SIO

N

462015 LS1154 - MTHILAKAR 36

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 9: Bioinformatic tools in Pheromone technology

RESULT PAGE ndash SELECTED ORGANISM MOUSE

462015 9LS1154 - MTHILAKAR

RESULTS ARE DOWNLOADABLE

462015 10LS1154 - MTHILAKAR

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

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UB

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SIO

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462015 LS1154 - MTHILAKAR 34

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 10: Bioinformatic tools in Pheromone technology

RESULTS ARE DOWNLOADABLE

462015 10LS1154 - MTHILAKAR

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

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UB

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SIO

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 11: Bioinformatic tools in Pheromone technology

ALIGNMENT

462015 11LS1154 - MTHILAKAR

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

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SE

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UB

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 12: Bioinformatic tools in Pheromone technology

ALIGNMENT - RESULT

462015 12LS1154 - MTHILAKAR

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

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SE

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CE

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462015 LS1154 - MTHILAKAR 35

DD

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462015 LS1154 - MTHILAKAR 36

DD

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SE

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CE

S

UB

MIS

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 13: Bioinformatic tools in Pheromone technology

ALIGNMENT - TREE RESULT

462015 13LS1154 - MTHILAKAR

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

BJ

SE

QU

EN

CE

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462015 LS1154 - MTHILAKAR 35

DD

BJ

SE

QU

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462015 LS1154 - MTHILAKAR 36

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 14: Bioinformatic tools in Pheromone technology

BLAST

462015 14LS1154 - MTHILAKAR

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 15: Bioinformatic tools in Pheromone technology

BLAST PAGE IN UNIPROT

462015 15LS1154 - MTHILAKAR

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

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CE

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UB

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SIO

N

462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 16: Bioinformatic tools in Pheromone technology

BLAST RESULTS

BLAST RESULTS

462015 16LS1154 - MTHILAKAR

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

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CE

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UB

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SIO

N

462015 LS1154 - MTHILAKAR 35

DD

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462015 LS1154 - MTHILAKAR 36

DD

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CE

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UB

MIS

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 17: Bioinformatic tools in Pheromone technology

DDBJ ndash DNA DATA BANK OF JAPAN

DDBJ provides freely available nucleotide sequence data and supercomputer system (for support in the research activities in Life sciences)

DDBJ is accessing from NIG-J with endorsement of Japanese Ministry ofEducation Culture Sports Science and Technology

DNA database Advisory committee (from outside of NIG) and INSDC aresupports and reviews the DDBJ activities

Major activities of DDBJ Center are as follows

Construction and operation of INSDC rules and regulations

Providing nucleotide and amino acid sequence data that are related topatent applications

Management and operation of the NIG Supercomputer System

Providing services to search and to analyze biological data

Training course and publication

462015 18LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

BJ

SE

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CE

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UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 35

DD

BJ

SE

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CE

S

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SIO

N

462015 LS1154 - MTHILAKAR 36

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 18: Bioinformatic tools in Pheromone technology

462015 LS1154 - MTHILAKAR 19

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

BJ

SE

QU

EN

CE

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UB

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N

462015 LS1154 - MTHILAKAR 35

DD

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N

462015 LS1154 - MTHILAKAR 36

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 19: Bioinformatic tools in Pheromone technology

DDBJ HOME PAGE AT httpddbjnigacjp

462015 20LS1154 - MTHILAKAR

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

462015 LS1154 - MTHILAKAR 34

DD

BJ

SE

QU

EN

CE

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UB

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SIO

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462015 LS1154 - MTHILAKAR 35

DD

BJ

SE

QU

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CE

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SIO

N

462015 LS1154 - MTHILAKAR 36

DD

BJ

SE

QU

EN

CE

S

UB

MIS

SIO

N

KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 20: Bioinformatic tools in Pheromone technology

COLLABORATIONSDDBJ is the member of INSDC (International Nucleotide Sequence DatabaseCollaboration)

DDBJ exchanges their data with EMBL at European Bioinformatics institute andwith Genbank at National center for Biotechnology Information on Daily basis

Thus three databanks contains same data at any time

462015 21LS1154 - MTHILAKAR

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

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462015 LS1154 - MTHILAKAR 34

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 21: Bioinformatic tools in Pheromone technology

462015 LS1154 - MTHILAKAR 22

EMBL HOME PAGE AT httpwwwemblorg

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

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462015 LS1154 - MTHILAKAR 34

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462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 22: Bioinformatic tools in Pheromone technology

462015 LS1154 - MTHILAKAR 23

NCBI HOME PAGE AT httpwwwncbinlmnihgov

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

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462015 LS1154 - MTHILAKAR 34

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 23: Bioinformatic tools in Pheromone technology

462015 LS1154 - MTHILAKAR 24

DDBJ SEARCH AND ANALYSIS PAGE AT httpwwwddbjnigacjpsearches-ehtml

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

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462015 LS1154 - MTHILAKAR 34

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 24: Bioinformatic tools in Pheromone technology

462015 LS1154 - MTHILAKAR 25

DDBJ ndash ARSA SEARCH

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

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462015 LS1154 - MTHILAKAR 34

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 25: Bioinformatic tools in Pheromone technology

462015 LS1154 - MTHILAKAR 26

DDBJ ndash GETENTRY SEARCH

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

DD

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462015 LS1154 - MTHILAKAR 34

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

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S

UB

MIS

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 26: Bioinformatic tools in Pheromone technology

462015 LS1154 - MTHILAKAR 27

DDBJ ndash GETENTRY SEARCH ndash RESULT PAGE FOR Y17566

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

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462015 LS1154 - MTHILAKAR 34

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462015 LS1154 - MTHILAKAR 35

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462015 LS1154 - MTHILAKAR 36

DD

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SE

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S

UB

MIS

SIO

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 27: Bioinformatic tools in Pheromone technology

DDBJ ndash DATA SUBMISSION

462015 28LS1154 - MTHILAKAR

462015 29LS1154 - MTHILAKAR

462015 30LS1154 - MTHILAKAR

462015 31LS1154 - MTHILAKAR

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

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462015 LS1154 - MTHILAKAR 34

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 28: Bioinformatic tools in Pheromone technology

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DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 29: Bioinformatic tools in Pheromone technology

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 30: Bioinformatic tools in Pheromone technology

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DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 31: Bioinformatic tools in Pheromone technology

462015 32LS1154 - MTHILAKAR

DDBJ SEQUENCE SUBMISSION PAGE httpddbjnigacjpsubmission

462015 LS1154 - MTHILAKAR 33

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 32: Bioinformatic tools in Pheromone technology

462015 LS1154 - MTHILAKAR 33

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 33: Bioinformatic tools in Pheromone technology

462015 LS1154 - MTHILAKAR 34

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 34: Bioinformatic tools in Pheromone technology

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 35: Bioinformatic tools in Pheromone technology

462015 LS1154 - MTHILAKAR 36

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KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 36: Bioinformatic tools in Pheromone technology

KEGG - INTRODUCTION

KEGG (Kyoto Encyclopedia of Genes and Genomes)

It is a database resource that integrates Genomic Chemical and Systemicfunctional informations

Manually creates a knowledge base for Bio-systemic function by capturing andorganizing Experimental knowledge in Computable forms

Such as KEGG pathway maps BRITE functional hierarchies and KEGG modules

It is a computer representation of Biological system consisting of MolecularBuilding blocks of Genes and Proteins (Genomic information) and Chemicalsubstances (Chemical information) that are integrated with the knowledge onMolecular Wiring Diagrams of interactions Reactions and Relation networks

It also contains the Disease and Drug information to the biological system

KEGG is widely used as reference knowledge base for integration of Largerdatasets generated by Genome sequencing and other High throughputexperiments

KEGG is developed by Kanehisa Laboratories (Minoru Kanehisa)462015 LS1154 - MTHILAKAR 38

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 37: Bioinformatic tools in Pheromone technology

462015 39LS1154 - MTHILAKAR

KEGG HOME PAGE AT httpwwwgenomejpkegg

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 38: Bioinformatic tools in Pheromone technology

462015 40LS1154 - MTHILAKAR

SEARCHING IN KEGG

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 39: Bioinformatic tools in Pheromone technology

462015 41LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 40: Bioinformatic tools in Pheromone technology

462015 42LS1154 - MTHILAKAR

SEARCH RESULTS IN KEGG

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 41: Bioinformatic tools in Pheromone technology

462015 43LS1154 - MTHILAKAR

KEGG SIGNALING PATHWAY IN YEAST

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 42: Bioinformatic tools in Pheromone technology

PYMOLOpen source User sponsored Molecular visualization systemcreated by Warren Lyfor DeLano and Commercialization initialized byDeLano Scientific LLC (A private software company)

It is currently commercialized by Schroumldinger Inc

PyMOL can produce High quality 3D images of small molecules andbiological macromolecules such as proteins

According to the original author of PyMOL almost frac14 of images ofproteins are published as identified

Accessible at httppymolorg

462015 LS1154 - MTHILAKAR 45

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 43: Bioinformatic tools in Pheromone technology

PYMOL HOME PAGE AT httppymolorg

462015 46LS1154 - MTHILAKAR

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 44: Bioinformatic tools in Pheromone technology

PYMOL SOFTWARE INSTALLED ON THIS WINDOWS

462015 47LS1154 - MTHILAKAR

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 45: Bioinformatic tools in Pheromone technology

462015 48LS1154 - MTHILAKAR

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 46: Bioinformatic tools in Pheromone technology

REFERENCEShttpwwwuniprotorg

httpwwwinsdcorg

httpwwwddbjnigacjp

httpwwwgenomejpkeggkegg1html

httpspymolorg

httpwwwncbinlmnihgov

httpwwwemblorg

httpenwikipediaorgwikiDNA_Data_Bank_of_Japan

KEGG databases for pathway prediction by Susumu Goto Presented at COSBi Seminar 2010

Introduction to KEGG by Susumu Goto Presented at Systems biology and Osmics cascade 2008

462015 LS1154 - MTHILAKAR 50

Page 47: Bioinformatic tools in Pheromone technology