Created By:

ANKIT UPADHYAYA

BIOINFORMATICS

INTRODUCATION

WHAT IS BIOINFORMATICS??

AIM OF BIOINFORMATICS

USEFUL DATABASE ON BIOINFORMATICS

BIOLOGICAL DATABASES

BIOLOGICAL DATABASES: WHY?

04/12/23 06:39

• Need for storing and communicating large datasets has grown

• Make biological data available to scientists.

• To make biological data available in computer-readable form.

DIFFERENT CLASSIFICATIONS OF DATABASES

04/12/23 06:39

• Type of data

• nucleotide sequences

• protein sequences

• proteins sequence patterns or motifs

• macromolecular 3D structure

• gene expression data

• metabolic pathways

DIFFERENT CLASSIFICATIONS OF DATABASES….

04/12/23 06:39

• Primary or derived databases

• Primary databases: experimental results directly into database

• Secondary databases: results of analysis of primary databases

• Aggregate of many databases

• Links to other data items

• Combination of data

• Consolidation of data

DIFFERENT CLASSIFICATIONS OF DATABASES….

04/12/23 06:39

• Technical design

• Flat-files

• Relational database (SQL)

• Exchange/publication technologies (FTP, HTML, CORBA, XML,...)

DIFFERENT CLASSIFICATIONS OF DATABASES….

04/12/23 06:39

• Availability

• Publicly available, no restrictions

• Available, but with copyright

• Accessible, but not downloadable

• Academic, but not freely available

• Proprietary, commercial; possibly free for academics

NUCLEOTIDE SEQUENCE DATABASES

PROTEIN SEQUENCE DATABSES

STRUCTURAL DATABASES

GENBANK(WEBSITE::HTTP://WWW.NCBI.NLM.NIH.GOV/GENBANK)

EMBL(WEBSITE::HTTP://WWW.EBI.AC.UK/EMBL/)

DDBJ(WEBSITE::HTTP://WWW.DDBJ.NIG.AC.JP)

APPLICATION

DEFINITIONS