biology chapter 5 form 5

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    The Role of the

    Circulatory System in theBodys Defence

    Mechanism

    Subtopic 1.5

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    Bodys defence mechanism against diseases

    3 lines of defence mechanism in the body:

    First Line

    of Defense

    Second

    Line of

    Defense

    Third Line

    of Defense

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    Includingskin

    mucous membranes

    Function

    to prevent pathogens from entering the body.

    Mucous Membrane

    consists of cells lining the respiratory tract andopenings of the urinary and reproductive systems.

    The membrane secretes a protective layer ofmucus.

    Mucus

    stickyand traps pathogens and other particles

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    The Second Line Of Defence

    Deals with pathogens(microorganisms that causeddisease) that have bypassed the

    first line of defence.

    Phagocyte(phagocytic white blood

    cells) digests the pathogensbyphagocytosisin order to destroythe pathogens.

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    The Third Line Of Defence

    Lymphocytes in the bloodproduce chemicals calledantibodiesthat destroy bacteriaand viruses before they getinside the body cells.

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    Immunity

    ability of an organism to resistinfection.

    Antigen

    a foreign substance capable ofstimulating an immune response orthe formation of antibodies.

    Examples of antigens are pathogens,toxic substances, and variousharmless molecules and cells.

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    Antibodies

    proteinsthat interact with the antigens andthereby rendering them harmless. Specificantibodies interact with specific antigens.

    Immunisation

    a technique used to induce immunity to aspecific disease in humans or other animalsby exposing the individual to an antigen in

    order to stimulate the production of specificantibodies.

    achieved through injection a vaccine thatcontains killed or severely weakened antigeninto the body of an individual.

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    Antibodies

    are proteins

    are produced by lymphocytesare in response to specificantigens

    provide immunity against certainmicroorganisms or their toxins

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    HIVHuman Immunodeficiency Virus)

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    HIVvirus that attacks the human immune

    system.

    leads toAIDS(Acquired Immunodeficiency

    Syndrome).

    A person who has AIDS is vulnerable tovarious infections because the immune

    system is being destroyed progressively.

    The infected person eventually diesofsecondary infections because the immune

    system collapses and is unable to defend

    the body against pathogens.

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    There are four main ways that HIV can be

    transmitted:

    Through any form of sexual intercourse

    with an infected person.

    Through contact with blood products ofan infected person.

    Through shared needles or syringes

    that are contaminated with blood of an

    infected person.From an infected mother to child, either

    during pregnancy, birth or breast

    feeding.

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    Infection of HIV virus in the blood

    stream