blood sugar levels homeostasis via negative feedback

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Page 1: Blood Sugar Levels Homeostasis via Negative Feedback
Page 2: Blood Sugar Levels Homeostasis via Negative Feedback

Blood Sugar LevelsHomeostasis via Negative Feedback

Page 3: Blood Sugar Levels Homeostasis via Negative Feedback

Obesity may be gene related

• Leptin leptin levels appetite - loss of body fat leptin levels and appetite

and wt gain

• potential medications for obesity

Page 4: Blood Sugar Levels Homeostasis via Negative Feedback

• An animal whose diet is missing one or more essential nutrients is said to be malnourished.

Giraffe eats bone to get phosphorus nutrient

Page 5: Blood Sugar Levels Homeostasis via Negative Feedback

• Vegetarian diet may result in protein deficiency

• Need essential amino acids– beans lysine – corn the methionine

Page 6: Blood Sugar Levels Homeostasis via Negative Feedback

• Healthy diets requires essential amino acids otherwise protein synthesis is retarded.

• Special adaptations during molting (non-feeding time)– uses their muscle proteins

as a source of amino acids to make new proteins

Page 7: Blood Sugar Levels Homeostasis via Negative Feedback

Healthy Diets Require:

• Water

• Carbs, Proteins, Lipids, Amino Acids

• Vitamins:

- water-soluble (thiamine, riboflavin, folic acid)

- fat-soluble (Vitamin A, D, E, K)

• Minerals (Fe, Ca, P, Na, K)

Page 8: Blood Sugar Levels Homeostasis via Negative Feedback

Water

• Solvent in which the chemistry of life occurs– cell chemistry occurs in an aqueous medium– water carries essential nutrients to cells– water carries metabolic wastes away from cells– hydrolysis & dehydration reaction– stabilizes body temp

Page 9: Blood Sugar Levels Homeostasis via Negative Feedback

Carbohydrates

• Energy Metabolism– catabolism of glucose during cellular

respiration yields ATP for energy-requiring activities

– glucose stored as glycogen in the liver and muscle cell fibers

– dietary fiber

Page 10: Blood Sugar Levels Homeostasis via Negative Feedback

Lipids

• Triglycerides (Fats)– energy storage molecules– protect and cushion delicate body

organs– source of the raw materials for the

construction of phospholipids– unsaturated versus saturated fats

Page 11: Blood Sugar Levels Homeostasis via Negative Feedback

Lipids

• Steroids (e.g., cholesterol)– precursor molecules for steroid

hormones, vitamin D, bile salts– fundamental component of plasma

membranes (influence membrane fluidity)– HDL-cholesterol versus LDL-cholesterol

Page 12: Blood Sugar Levels Homeostasis via Negative Feedback

Proteins

• Enzymes• Structural proteins (shape and

form of cells and tissues)• Hormones• Immunoglobulins (antibodies)

Page 13: Blood Sugar Levels Homeostasis via Negative Feedback

Vitamins

• Organic compounds needed by the body in small, but essential amounts

• Cannot be synthesized by the body in sufficient amounts

• Function in a variety of ways in metabolic reactions

• Thirteen known vitamins

Page 14: Blood Sugar Levels Homeostasis via Negative Feedback

Minerals

• Essential inorganic elements

• Involved in a variety of metabolic processes

• Major minerals versus trace minerals

Page 15: Blood Sugar Levels Homeostasis via Negative Feedback

Feeding Types:

• Herbivores

• Carnivores

• Omnivores

• Detritivores

Page 16: Blood Sugar Levels Homeostasis via Negative Feedback

Some Feeding TypesSome Feeding TypesMany species don’t fit into convenient categories

• Algal Grazers and Browsers• Suspension Feeding• Filter Feeding• Deposit Feeding• Benthic Animal Predators• Plankton Pickers• Corallivores• Piscivores• Omnivores• Detritivores• Scavengers• Parasites• Cannibals• Ontogenetic dietary shifts

Page 17: Blood Sugar Levels Homeostasis via Negative Feedback

Overview of Food Processing

The four main stages of food processing:

1. Ingestion

2. Digestion

3. Absorption

4. Elimination

Page 18: Blood Sugar Levels Homeostasis via Negative Feedback

Digestion occurs in specialized compartments

The simplest digestive compartments are food vacuoles; it is a process termed intracellular digestion

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Gastrovascular cavity

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Complete Digestive Tracts (Alimentary Canal)

Page 21: Blood Sugar Levels Homeostasis via Negative Feedback

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 41.13

Page 22: Blood Sugar Levels Homeostasis via Negative Feedback

Digestive ProcessDigestive Process

1.1. IngestionIngestion2.2. PropulsionPropulsion3.3. Mechanical DigestionMechanical Digestion

• MasticationMastication• Churning food in stomachChurning food in stomach

4.4. Chemical digestionChemical digestion5.5. AbsorptionAbsorption6.6. DefecationDefecation

Page 23: Blood Sugar Levels Homeostasis via Negative Feedback

incisors

cuspid

premolars

molars

TeethTeeth

Page 24: Blood Sugar Levels Homeostasis via Negative Feedback

enameldentinpulp cavity

root canal

bone

blood vessels

crown

neck

root

Page 25: Blood Sugar Levels Homeostasis via Negative Feedback

Salivary Glands

Salivary Glands

Page 26: Blood Sugar Levels Homeostasis via Negative Feedback

Saliva

watermucin

amylase

Page 27: Blood Sugar Levels Homeostasis via Negative Feedback

The Tongue

Page 28: Blood Sugar Levels Homeostasis via Negative Feedback

Taste Buds

papilla

taste bud

taste pore

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Page 30: Blood Sugar Levels Homeostasis via Negative Feedback
Page 31: Blood Sugar Levels Homeostasis via Negative Feedback

Peristalsis

Page 32: Blood Sugar Levels Homeostasis via Negative Feedback

The Stomach

esophaguscardiac sphincter

pyloric sphincterduodenum

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Stomach Secretions

Gastric Gland:Gastric Gland:Mucus cellsMucus cellsChief cellsChief cells

Parietal cellsParietal cells

Page 34: Blood Sugar Levels Homeostasis via Negative Feedback

Mucous neck cells- found in upper region of gastric glands produce• mucous

 Parietal cells- in gastric gland of mucosa

produce• HCl – kills most bacteria• Intrinsic factor (required for absorption of vit. B12 in sm intestine, which is needed for producing mature erythrocytes)

 Zymogenic (chief) cells-

produce• pepsinogen (inactive form of pepsin, which becomes active in presence of HCl) • rennin (milk digestion in children) protein digestion

Page 35: Blood Sugar Levels Homeostasis via Negative Feedback

 

Enteroendocrine cells in stomach mucosaproduces:

• Gastrin- regulates stomach secretions and mobility• Histamine- activates parietal cells to release HCl• Endorphins- natural opiates• Serotonin- causes contraction of stomach muscle• Cholecystokinin (CCK)- (in duodenal mucosa) many

functions and affects many organs• Somatostatin- (stomach and duodenal mucosa) -

inhibits gastrin, pancreatic secretions, inhibits GI blood flow in sm intestine…

Page 36: Blood Sugar Levels Homeostasis via Negative Feedback

Gastric ulcers: • erosion of stomach wall• pain occurs 1-3 hrs after eating• new research90% of recurrent ulcers

due to bacterial infection (Helicobacter pylori), which destroys mucous protective barrier

• use antibiotic therapy to kill bacteria

Page 37: Blood Sugar Levels Homeostasis via Negative Feedback
Page 38: Blood Sugar Levels Homeostasis via Negative Feedback

• Many of the protein-digesting enzymes, such as aminopeptidase, are secreted by the intestinal epithelium, but trypsin, chymotrypsin, and carboxypeptidase are secreted in inactive form by the pancreas.– Another intestinal enzyme,

enteropeptidase, converts inactive trypsinogen into active trypsin.

– Active trypsin then activates the other two.

Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings

Fig. 41.18

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Pancreatic Enzymestrypsin

chemotrypsin

carboxypeptidase

amylase

phospholipase

lipase

nucleases

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Page 41: Blood Sugar Levels Homeostasis via Negative Feedback
Page 42: Blood Sugar Levels Homeostasis via Negative Feedback

lumenmuscle layers

foldsvilli

Intestinal StructureIntestinal Structure

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epithelial cells

capillaries

lacteal

Intestinal VillusIntestinal Villus

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Page 45: Blood Sugar Levels Homeostasis via Negative Feedback

stomach

duodenum pancreas

pancreatic duct

common bile duct

gallbladder

liver

Page 46: Blood Sugar Levels Homeostasis via Negative Feedback

Bilebile saltsbile salts

bile pigmentsbile pigments

Page 47: Blood Sugar Levels Homeostasis via Negative Feedback

Intestinal Membrane Enzymes

disaccharidasesdisaccharidasesaminopeptidaseaminopeptidase

dipeptidasesdipeptidasesnucleotidasesnucleotidasesnucleosidasesnucleosidases

Page 48: Blood Sugar Levels Homeostasis via Negative Feedback

cecum appendix

ascending colon

transverse colon

descending

colon

sigmoidal

colon

rectum

internal anal sphincter external anal sphincter

anal canal

Page 49: Blood Sugar Levels Homeostasis via Negative Feedback

• Dentition, an animal’s assortment of teeth, is one example of structural

variation reflecting diet.

Page 50: Blood Sugar Levels Homeostasis via Negative Feedback

Deep sea gulper

Large expandable stomach

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• The length of the vertebrate digestive system is also correlated with diet.

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• Cellulose is difficult to digest• Termites have symbiotic

bacteria• Some bacteria and protists

have enzymes that hydrolyze cellulose

Symbiotic microorganisms aid in digestion

Page 53: Blood Sugar Levels Homeostasis via Negative Feedback