Blood

The different components of blood

RBC’s/ErythrocytesTransports O2 (on hemoglobin)

Transports CO2 (on hemoglobin)

LEUKOCYTE FUNCTION: SEE TALBE 21.3—GREAT FUNCTION SUMMARY

Leukocytes Functions

Lymphocyte

Basophil

Neutrophil

eosinophil

Monocyte

Leukocytes—WBC’s• Granulocytes: have

granules in cytoplasm• Agranulocytes: no

granules in cytoplasm

NeutrophilsFunction• Phagocytize pathogens

– particularly bacteria

Structure/ID• Multilobed (3-5) nucleus• Inconspicuous granules• ~2x size of rbc

EosinophilFunction• Kills/attacks parasites• Phagocytize allergens and antigen antibody complexes

– reduces inflammation and allergic rxns

Structure/ID• ~ 2x size of rbc• Very conspicuous red granules• Bilobed nucleus

BasophilFunction• produces histamine and heparin

– Promote inflamation:

Structure/ID• ~2x size of rbc• Bilobed nuclues• Very conspicuous blue granules

MonocytesFunction• Leaves vessels and then

phagocytizes microorganisms

and debri

Structure/ID• ~ 3x size of RBC/largest WBC• Lobed kidney shaped nucleus• No granules

lymphocyteFunction• Produces antibodies (specific immunity)

Structure/ID• Slightly larger then rbc• Round Nucleus fills most of cell• No granules

Comparing Leukocytes

A

D

CB

PlateletsFunction• Reduce blood loss• Platelet plug/clotting

Stucture/ID• Cell fragments• Small (much smaller then rbc),

darkish

Relative Abundance of Leukocyes

Never Let Monkeys Eat Bananas

»Nuetrophils (most common wbc)

»Lymphocytes

»Monocytes

»Eosinophils»Basophils (least common wbc)

Differential WBC countBecause:• there is a typical amount of each WBC• Each WBC has a different function• WBC respond to their specific challenges

by increasing in number

• Counting the relative abundance of each WBC (differential WBC count) can help assess what a condition/problem is

Normal WBC Frequencies

Blood Cell Normal Value

Neutophil 52-62%

Eosinophil 1-3%

Basophil Less then 1%

Lymphocyte 25-33%

Monocyte 3-9%